Browse by Research Team

2008

Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
Gratze, P., Dechend, R., Stocker, C., Park, J.K., Feldt, S., Shagdarsuren, E., Wellner, M., Gueler, F., Rong, S., Gross, V., Obst, M., Plehm, R., Alenina, N., Zenclussen, A., Titze, J., Small, K., Yokota, Y., Zenke, M., Luft, F.C. and Mueller, D.N.
Circulation 117 (20): 2645-2656. 20 May 2008

2005

GandrKB - ontological microarray annotation and visualization.
Schober, D., Leser, U., Zenke, M. and Reich, J.
Bioinformatics 21 (11): 2785-2786. 1 January 2005

Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R., Janz, M., Mapara, M.Y., Lemke, B., Stirling, D., Doerken, B., Zenke, M. and Lentzsch, S.
Blood 105 (10): 3833-3840. 1 January 2005

Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration.
Prechtel, A.T., Turza, N.M., Kobelt, D.J., Eisemann, J.I., Coffin, R.S., McGrath, Y., Hacker, C., Ju, X.S., Zenke, M. and Steinkasserer, A.
Journal of General Virology 86 (6): 1645-1657. 1 January 2005

Membrane proteinase 3 expression in patients with Wegener's granulomatosis and in human hematopoietic stem cell-derived neutrophils.
Schreiber, A., Otto, B., Ju, X., Zenke, M., Goebel, U., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 16 : 2216-2224. 1 January 2005

Progressive and controlled development of mouse dendritic cells from Flt3+ CD11b+ progenitors in vitro.
Hieronymus, T., Gust, T.C., Kirsch, R.D., Jorgas, T., Blendinger, G., Goncharenko, M., Supplitt, K., Rose-John, S., Mueller, A.M. and Zenke, M.
Journal of Immunology 174 (5): 2552-2562. 1 January 2005

2004

Immunoglobulin-like transcripts ILT2, ILT3 and ILT7 are expressed by human dendritic cells and down-regulated following activation.
Ju, X.S., Hacker, C., Scherer, B., Redecke, V., Berger, T., Schuler, G., Wagner, H., Lipford, G.B. and Zenke, M.
Gene 331 (1-2): 159-164. 28 April 2004

RNA-containing adenovirus/polyethylenimine transfer complexes effectively transduce dendritic cells and induce antigen-specific T cell responses.
Gust, T.C., Diebold, S.S., Cotten, M. and Zenke, M.
Journal of Gene Medicine 6 (4): 464-470. 1 April 2004

2003

Therapeutics and diagnostics for disorders of erythropoiesis.
Lemke, B., Zenke, M., Hacker, C., Brissette, W.H., Zagouras, P. and Neote, K.S.
WO03038130 ; US2004014064 ; EP1446507. 8 May 2003

Mittel zur Behandlung von leukaemischen Erkrankungen.
Zenke, M., Bartunek, P., Madruga, J. and Koritschoner, N.P.
DE10150183A1. 24 April 2003

TR4, TR4 activators, TR4 inhibitors or TR4-associated molecules for treating leukaemic diseases [TR4, TR4-Aktivatoren, TR4-Inhibitoren oder TR4-assoziierten Molekuelen zur Behandlung von leukaemischen Erkrankungen].
Zenke, M., Bartunek, P., Madruga, J. and Koritschoner, M.P.
WO0333529. 24 April 2003

GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter.
Bartunek, P., Kralova, J., Blendinger, G., Dvorak, M. and Zenke, M.
Oncogene 22 (13): 1927-1935. 3 April 2003

Transcriptional profiling identifies Id2 function in dendritic cell development.
Hacker, C., Kirsch, R.D., Ju, X.S., Hieronymus, T., Gust, T.C., Kuhl, C., Jorgas, T., Kurz, S.M., Rose-John, S., Yokota, Y. and Zenke, M.
Nature Immunology 4 (4): 380-386. April 2003

Cryopreservation of mature monocyte-derived human dendritic cells for vaccination: influence on phenotype and functional properties.
Westermann, J., Koerner, I.J., Kopp, J., Kurz, S., Zenke, M., Doerken, B. and Pezzutto, A.
Cancer Immunology Immunotherapy 52 (3): 194-198. March 2003

Methods and compositions relating to plasmacytoid dendritic cells.
Lipford, G.B., Wagner, H. and Zenke, M.
WO0312061 ; US2003148316. 13 February 2003

Towards determining the differentiation program of antigen-presenting dentritic cells by transcriptional profiling.
Ju, X.S., Hacker, C., Kurz, S.M., Knespel, S., Blendinger, G., Rose-John, S. and Zenke, M.
European Journal of Cell Biology 82 (2): 75-86. February 2003

Differentiation of human antigen-presenting dendritic cells from CD34+ hematopoietic stem cells in vitro.
Ju, X.S. and Zenke, M.
Methods in Molecular Biology 215 : 399-407. 2003

2002

Immunosuppressive treatment protects against angiotensin II-induced renal damage.
Muller, D.N., Shagdarsuren, E., Park, J.K., Dechend, R., Mervaala, E., Hampich, F., Fiebeler, A., Ju, X., Finckenberg, P., Theuer, J., Viedt, C., Kreuzer, J., Heidecke, H., Haller, H., Zenke, M. and Luft, F.C.
American Journal of Pathology 161 (5): 1679-1693. November 2002

Mannose receptor-mediated gene delivery into antigen presenting dendritic cells.
Diebold, S.S., Plank, C., Cotten, M., Wagner, E. and Zenke, M.
Somatic Cell and Molecular Genetics 27 (1-6): 65-74. November 2002

Myb-transformierte Blutzellen und ihre Verwendung zum Wirkstoffscreening [MYB-transformed blood cells and their use for active ingredient screening].
Bartunek, P., Dvorak, M., Zenke, M. and Karafiat, V.
DE10112360A1 ; WO02072116 ; CZ20032431 ; EP1365783. 12 September 2002

Transformierte Blutzellen und ihre Verwendung zum Wirkstoffscreening.
Bartunek, P., Dvorak, M., Zenke, M. and Karafiat, V.
DE10112360A1. 12 September 2002

Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M., Lemke, P., Anagnostopoulos, I., Hacker, C., Krappmann, D., Mathas, S., Doerken, B., Zenke, M., Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196 (5): 605-617. 2 September 2002

[Regulation of bone mass for skeletal loading] [Article in Japanese].
Sakai, A., Tanaka, S., Sakata, T., Watanuki, M., Zenke, M. and Nakamura, T.
Journal of UOEH 24 : 281-287. 1 September 2002

Receptor-mediated gene delivery.
Gust, T.C. and Zenke, M.
ScientificWorldJournal 2 : 224-229. 24 January 2002

bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors.
Bartunek, P., Pajer, P., Karafiat, V., Blendinger, G., Dvorak, M. and Zenke, M.
Oncogene 21 (3): 400-410. 17 January 2002

The impact of c-met/scatter factor receptor on dendritic cell migration.
Kurz, S.M., Diebold, S.S., Hieronymus, T., Gust, T.C., Bartunek, P., Sachs, M., Birchmeier, W. and Zenke, M.
European Journal of Immunology 32 (7): 1832-1838. 1 January 2002

2001

MHC class II presentation of endogenously expressed antigens by transfected dendritic cells.
Diebold, S.S., Cotten, M., Koch, N. and Zenke, M.
Gene Therapy 8 (6): 487-493. 1 January 2001

Molecular cloning, expression and regulation of the avian tubby-like protein 1 (tulp1) gene.
Heikenwaelder, M.F., Koritschoner, N.P., Pajer, P., Chaboissier, M.C., Kurz, S.M., Briegel, K.J., Bartunek, P. and Zenke, M.
Gene 273 (1): 131-139. 1 January 2001

The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors.
Karafiat, V., Dvorakova, M., Pajer, P., Kralova, J., Horejsi, Z., Cermak, V., Bartunek, P., Zenke, M. and Dvorak, M.
Blood 98 (13): 3668-3676. 1 January 2001

The nuclear orphan receptor TR4 promotes proliferation of myeloid progenitor cells.
Koritschoner, N.P., Madruga, J., Knespel, S., Blendinger, G., Anzinger, B., Otto, A., Zenke, M. and Bartunek, P.
Cell Growth and Differentiation 12 (11): 563-572. 1 January 2001

Thyroid hormone regulates the obesity gene tub.
Koritschoner, N.P., Alvarez-Dolado, M., Kurz, S.M., Heikenwaelder, M.F., Hacker, C., Vogel, F., Munoz, A. and Zenke, M.
EMBO Reports 2 (6): 499-504. 1 January 2001

2000

Dendritic cells conditionally transformed by v-relER oncogene express lymphoid marker genes.
Madruga, J., Briegel, K., Diebold, S., Boehmelt, G., Vogel, F. and Zenke, M.
Immunobiology 202 (4): 394-407. 1 November 2000

1999

Identification of a mammalian homologue of the fungal Tom70 mitochondrial precursor protein import receptor as a thyroid hormone-regulated gene in specific brain regions.
Alvarez-Dolado, M., Gonzalez-Moreno, M., Valencia, A., Zenke, M., Bernal, J. and Munoz, A.
Journal of Neurochemistry 73 (6): 2240-2249. December 1999

The fibroblast growth factor receptor FGFR-4 acts as a ligand dependent modulator of erythroid cell proliferation.
Koritschoner, N.P., Bartunek, P., Knespel, S., Blendinger, G. and Zenke, M.
Oncogene 18 (43): 5904-5914. 21 October 1999

Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells.
Diebold, S.S., Kursa, P., Wagner, E., Cotten, M. and Zenke, M.
Journal of Biological Chemistry 274 : 19087-19094. 2 July 1999

Molecular cloning, expression and evolutionary analysis of the avian tyrosine kinase JAK1.
Bartunek, P., Koritschoner, N.P., Brett, D. and Zenke, M.
Gene 230 : 129-136. 16 April 1999

Efficient gene delivery into human dendritic cells by adenovirus polyethylenimine and mannose polyethylenimine transfection.
Diebold, S.S., Lehrmann, H., Kursa, M., Wagner, E., Cotten, M. and Zenke, M.
Human Gene Therapy 10 : 775-786. 20 March 1999

Polarised expression pattern of focal contact proteins in highly motile antigen presenting dendritic cells.
Madruga, J., Koritschoner, N.P., Diebold, S.S., Kurz, S.M. and Zenke, M.
Journal of Cell Science 112 : 1685-1696. 1 January 1999

1998

Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro.
Panzenboeck, B., Bartunek, P., Mapara, M.Y. and Zenke, M.
Blood 92 (10): 3658-3668. 15 November 1998

Retinoid X receptor and c-erbA/ thyroid hormone receptor regulate erythroid cell growth and differentiation.
Bartunek, P. and Zenke, M.
Molecular Endocrinology 12 (9): 1269-1279. September 1998

Assignment of the gene encoding the core promoter element binding protein (COPEB) to human chromosome 10p15 by somatic hybrid analysis and fluorescence in situ hybridization.
Onyango, P., Koritschoner, N.P., Patrito, L.C., Zenke, M. and Weith, A.
Genomics 48 : 143-144. 1 January 1998

Gene-modified dendritic cells by receptor-mediated transfection.
Diebold, S.S., Cotten, M., Wagner, E. and Zenke, M.
Advances in Experimental Medicine and Biology 451 : 449-455. 1 January 1998

1997

The Myb leucine zipper is essential for leukemogenicity of the v-Myb protein.
Bartunek, P., Karafiat, V., Dvorakova, M., Zahorova, V., Mandikova, S., Zenke, M. and Dvorak, M.
Oncogene 15 (24): 2939-2949. 11 December 1997

Insulin-like growth factor type I (IGF-I) supports growth of V-relER dendritic cell progenitors.
Madruga, J., Koritschoner, N., Stengl, G., Knespel, S., Bartunek, P. and Zenke, M.
Advances in Experimental Medicine and Biology 417 : 461-465. 1 January 1997

1996

Regulation and function of transcription factor GATA-1 during red blood cell differentiation.
Briegel, K., Bartunek, P., Stengl, G., Lim, K.C., Beug, H., Engel, J.D. and Zenke, M.
Development 122 (12): 3839-3850. December 1996

Avian stem cell factor (SCF): production and characterization of the recombinant His- tagged SCF of chicken and its neutralizing antibody.
Bartunek, P., Pichlikova, L., Stengl, G., Boehmelt, G., Martin, F.H., Beug, H., Dvorak, M. and Zenke, M.
Cytokine 8 (1): 14-20. 1 January 1996

1995

Dendritic cell progenitor is transformed by a conditional v-rel estrogen receptor fusion v-relER.
Boehmelt, G., Madruga, J., Doerfler, P., Briegel, K., Schwarz, H., Enrietto, P. and Zenke, M.
Cell 80 (2): 341-352. 27 January 1995

Generation of cell lines from embryonic quail retina capable of mature neuronal differentiation.
Pollerberg, G.E., Kuschel, C. and Zenke, M.
Journal of Neuroscience Research 41 : 427-442. 1 January 1995

1994

Structure and expression of the chicken retinoblastoma gene.
Boehmelt, G., Ulrich, E., Kurzbauer, R., Mellitzer, G., Bird, A. and Zenke, M.
Cell Growth and Differentiation 5 : 221-230. 1 January 1994

1993

A conserved C-terminal sequence that is deleted in v-erbA is essential for the biological activities of c-erbA (the thyroid hormone receptor).
Saatcioglu, F., Bartunek, P., Deng, T., Zenke, M. and Karin, M.
Molecular and Cellular Biology 13 (6): 3675-3685. June 1993

Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.
Barettino, D., Bugge, T.H., Bartunek, P., Vivanco Ruiz, M.D., Sonntag-Buck, V., Beug, H., Zenke, M. and Stunnenberg, H.G.
EMBO Journal 12 (4): 1343-1354. April 1993

Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.
Briegel, K., Lim, K.C., Plank, C., Beug, H., Engel, J.D. and Zenke, M.
Genes & Development 7 : 1097-1109. 1 January 1993

1992

Hormone-regulated v-rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression.
Boehmelt, G., Walker, A., Kabrun, N., Mellitzer, G., Beug, H., Zenke, M. and Enrietto, P.J.
EMBO Journal 11 (12): 4641-4652. December 1992

Modulation of normal erythroid differentiation by the endogenous thyroid hormone and retinoic acid receptors: a possible target for v-erbA oncogene action.
Schroeder, C., Gibson, L., Zenke, M. and Beug, H.
Oncogene 7 (2): 217-227. 1 February 1992

Cis and transregulation of issue-specific transcription.
Engel, J.D., Beug, H., LaVail, J.H., Zenke, M., Mayo, K., Leonard, M.W., Foley, K.P., Yang, Z., Kornhauser, J.M., Ko, L.J., Lim, K.C., George, K.M. and Briegel, K.
Journal of Cell Science 16 : 21-31. 1 January 1992

Constitutive myc expression impairs hypertrophy and calcification in cartilage.
Quarto, R., Dozin, B., Tacchetti, C., Robino, G., Zenke, M., Campanile, G. and Cancedda, R.
Developmental Biology 149 (1): 168-176. 1 January 1992