Browse by Research Team

2023

Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J. and Sundaravinayagam, D. and Blume, A. and Marg, A. and Grunwald, S. and Metzler, E. and Escobar, H. and Müthel, S. and Wang, H. and Wollersheim, T. and Weber-Carstens, S. and Akalin, A. and Di Virgilio, M. and Tursun, B. and Spuler, S.
International Journal of Molecular Sciences 24 (3): 2772. 1 February 2023

2022

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G. and Blume, A. and Demirel, F.G. and Bulut, S. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 73 (1): 5-17. June 2022

Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 72 (5): 175-184. May 2022

2021

Induced neurons from germ cells in Caenorhabditis elegans.
Marchal, I. and Tursun, B.
Frontiers in Neuroscience 15 : 771687. 3 December 2021

The C. elegans pseudogene sspt-16 (F55A3.7) is required to safeguard germ cells against reprogramming.
Ofenbauer, A. and Kraus, C.M. and Tursun, B.
microPublication Biology 2021 18 May 2021

The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M. and Farré i Díaz, C. and Ofenbauer, A. and Herzog, S. and Tursun, B.
Nucleic Acids Research 49 (4): e22. 26 February 2021

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G. and Blume, A. and Gerceker Demirel, F. and Bulut, S. and Mertins, P. and Tursun, B.
bioRxiv : 2021.02.14.431134. 14 February 2021

2020

Conversion of germ cells to somatic cell types in C. elegans.
Ul Fatima, N. and Tursun, B.
Journal of Developmental Biology 8 (4): 24. December 2020

The CONDOR pipeline for simultaneous knockdown of multiple genes identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M. and Díaz, C.F. and Ofenbauer, A. and Tursun, B.
bioRxiv : 2020.09.01.276972. 1 September 2020

Epigenetic chaperoning of aging.
Müthel, S. and Tursun, B.
Aging 12 (2): 1044-1046. 31 January 2020

2019

Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A. and Sengul, T.G. and You, X. and Wang, Y. and Steil, L. and Bergmann, N. and Radke, M.H. and Ofenbauer, A. and Gesell-Salazar, M. and Balogh, A. and Kempa, S. and Tursun, B. and Robbins, C.T. and Völker, U. and Chen, W. and Nelson, L. and Gotthardt, M.
Scientific Reports 9 (1): 19976. 27 December 2019

Strategies for in vivo reprogramming.
Ofenbauer, A. and Tursun, B.
Current Opinion in Cell Biology 61 : 9-15. December 2019

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S. and Uyar, B. and He, M. and Krause, A. and Vitrinel, B. and Bulut, S. and Vasiljevic, D. and Marchal, I. and Kempa, S. and Akalin, A. and Tursun, B.
Aging Cell 18 (6): e13012. December 2019

CRISPR-activation-based screen reveals neuronal fate promotion by polycomb repressive complex 2 during direct reprogramming.
Wolfram, T. and Tursun, B.
Stem Cell Investigation 6 : 32. September 2019

HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K. and Franke, V. and Uyar, B. and Wurmus, R. and Bulut, S. and Tursun, B. and Akalin, A.
Nucleic Acids Research : gkz460. 20 June 2019

The conserved histone chaperone LIN-53 links lifespan and healthspan regulation in C. elegans.
Müthel, S. and Uyar, B. and He, M. and Krause, A. and Vitrinel, B. and Bulut, S. and Vasiljevic, D. and Akalin, A. and Kempa, S. and Tursun, B.
bioRxiv : 539015. 2 February 2019

Caenorhabditis elegans and systems biology - it is 'systems' all the way down!
Dupuy, D. and Tursun, B.
Current Opinion in Systems Biology 13 : iv-vi. February 2019

MRG-1/MRG15 is a barrier for germ cell to neuron reprogramming in Caenorhabditis elegans.
Hajduskova, M. and Baytek, G. and Kolundzic, E. and Gosdschan, A. and Kazmierczak, M. and Ofenbauer, A. and Beato del Rosal, M.L. and Herzog, S. and ul Fatima, N. and Mertins, P. and Seelk-Müthel, S. and Tursun, B.
Genetics 211 (1): 121-139. 1 January 2019

2018

Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
Nature Communications 9 (1): 4472. 26 October 2018

Transdifferentiation: do transition states lie on the path of development?
Reid, A. and Tursun, B.
Current Opinion in Systems Biology 11 : 18-23. October 2018

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. and Ofenbauer, A. and Bulut, S.I. and Uyar, B. and Baytek, G. and Sommermeier, A. and Seelk, S. and He, M. and Hirsekorn, A. and Vucicevic, D. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

The UNC-83/UNC-84 LINC members are required for body wall muscle nuclei positioning in C. elegans.
Ofenbauer, A. and Tursun, B.
Matters Select 31 May 2018

Application of RNAi and heat-shock-induced transcription factor expression to reprogram germ cells to neurons in C. elegans.
Kolundzic, E. and Seelk, S. and Tursun, B.
Journal of Visualized Experiments (131): e56889. 1 January 2018

2017

Determinants of transcription initiation directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
bioRxiv : 224642. 24 November 2017

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
Kolundzic, E. and Ofenbauer, A. and Uyar, B. and Sommermeier, A. and Seelk, S. and He, M. and Baytek, G. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
bioRxiv : 185116. 6 September 2017

Strategies for analyzing bisulfite sequencing data.
Wreczycka, K. and Gosdschan, A. and Yusuf, D. and Gruening, B. and Assenov, Y. and Akalin, A.
bioRxiv : 109512. 9 August 2017

Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans.
Wilhelm, T. and Byrne, J. and Medina, R. and Kolundžić, E. and Geisinger, J. and Hajduskova, M. and Tursun, B. and Richly, H.
Genes & Development 31 (15): 1561-1572. 1 August 2017

Neuronal inhibition of the autophagy nucleation complex extends lifespan in post-reproductive C. elegans.
Wilhelm, T. and Byrne, J. and Medina, R. and Kolundzic, E. and Geisinger, J. and Hajduskova, M. and Tursun, B. and Richly, H.
bioRxiv : 135178. 8 May 2017

PcG proteins in caenorhabditis elegans.
Tursun, B.
In: Polycomb Group Proteins. Translational Epigenetics Series . Elsevier / Academic Press, Amsterdam, 289-315. ISBN 978-0-12-809737-3 6 January 2017

2016

G-quadruplex prediction in E. coli genome reveals a conserved putative G-quadruplex-hairpin-duplex switch.
Kaplan, O.I. and Berber, B. and Hekim, N. and Doluca, O.
Nucleic Acids Research 44 (19): 9083-9095. 2 November 2016

Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons.
Seelk, S. and Adrian-Kalchhauser, I. and Hargitai, B. and Hajduskova, M. and Gutnik, S. and Tursun, B. and Ciosk, R.
eLife 5 : e15477. 7 September 2016

A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large.
Waaijers, S. and Muñoz, J. and Berends, C. and Ramalho, J.J. and Goerdayal, S.S. and Low, T.Y. and Zoumaro-Djayoon, A.D. and Hoffmann, M. and Koorman, T. and Tas, R.P. and Harterink, M. and Seelk, S. and Kerver, J. and Hoogenraad, C.C. and Bossinger, O. and Tursun, B. and van den Heuvel, S. and Heck, A.J.R. and Boxem, M.
BMC Biology 14 (1): 66. 9 August 2016

2015

G-quadruplex prediction in E.coli genome reveals a conserved putative G-quadruplex-hairpin-duplex switch.
Doluca, O. and Kaplan, O.I. and Berber, B. and Hekim, N.
bioRxiv : 032615. 24 November 2015

2014

Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1.
Cochella, L. and Tursun, B. and Hsieh, Y.W. and Galindo, S. and Johnston, R.J. and Chuang, C.F. and Hobert, O.
Genes & Development 28 (1): 34-43. 1 January 2014

2013

Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain.
Cevik, S. and Sanders, A.A.W.M. and Van Wijk, E. and Boldt, K. and Clarke, L. and van Reeuwijk, J. and Hori, Y. and Horn, N. and Hetterschijt, L. and Wdowicz, A. and Mullins, A. and Kida, K. and Kaplan, O.I. and van Beersum, S.E.C. and Man Wu, K. and Letteboer, S.J.F. and Mans, D.A. and Katada, T. and Kontani, K. and Ueffing, M. and Roepman, R. and Kremer, H. and Blacque, O.E.
PLoS Genetics 9 (12): e1003977. December 2013

ECM modulated early kidney development in embryonic organ culture.
Sebinger, D.D. and Ofenbauer, A. and Gruber, P. and Malik, S. and Werner, C.
Biomaterials 34 (28): 6670-6682. September 2013

2012

Removal of polycomb repressive complex 2 makes C. elegans germ cells susceptible to direct conversion into specific somatic cell types.
Patel, T. and Tursun, B. and Rahe, D.P. and Hobert, O.
Cell Reports 2 (5): 1178-1186. 29 November 2012

Cellular reprogramming processes in Drosophila and C. elegans.
Tursun, B.
Current Opinion in Genetics & Development 22 (5): 475-484. October 2012

2011

Direct conversion of C. elegans germ cells into specific neuron types.
Tursun, B. and Patel, T. and Kratsios, P. and Hobert, O.
Science 331 (6015): 304-308. 21 January 2011

2010

The Groucho ortholog UNC-37 interacts with the short Groucho-like protein LSY-22 to control developmental decisions in C. elegans.
Flowers, E.B. and Poole, R.J. and Tursun, B. and Bashllari, E. and Pe'er, I. and Hobert, O.
Development 137 (11): 1799-1805. June 2010

Neuron-type specific regulation of a 3'UTR through redundant and combinatorially acting cis-regulatory elements.
Didiano, D. and Cochella, L. and Tursun, B. and Hobert, O.
RNA 16 (2): 349-363. February 2010

2009

The C. elegans Tailless/TLX transcription factor nhr-67 controls neuronal identity and left/right asymmetric fate diversification.
Sarin, S. and Antonio, C. and Tursun, B. and Hobert, O.
Development 136 (17): 2933-2944. September 2009

A toolkit and robust pipeline for the generation of fosmid-based reporter genes in C. elegans.
Tursun, B. and Cochella, L. and Carrera, I. and Hobert, O.
PLoS ONE 4 (3): e4625. 4 March 2009

Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer.
Johnsen, S.A. and Guengoer, C. and Prenzel, T. and Riethdorf, S. and Riethdorf, L. and Taniguchi-Ishigaki, N. and Rau, T. and Tursun, B. and Furlow, J.D. and Sauter, G. and Scheffner, M. and Pantel, K. and Gannon, F. and Bach, I.
Cancer Research 69 (1): 128-136. 1 January 2009

2007

Proteasomal selection of multiprotein complexes recruited by LIM homeodomain transcription factors.
Guengoer, C. and Taniguchi-Ishigaki, N. and Ma, H. and Drung, A. and Tursun, B. and Ostendorff, H.P. and Bossenz, M. and Becker, C.G. and Becker, T. and Bach, I.
Proceedings of the National Academy of Sciences of the United States of America 104 (38): 15000-15005. 18 September 2007

2006

Dynamic expression of LIM cofactors in the developing mouse neural tube.
Ostendorff, H.P. and Tursun, B. and Cornils, K. and Schlueter, A. and Drung, A. and Guengoer, C. and Bach, I.
Developmental Dynamics 235 (3): 786-791. March 2006

2005

The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.
Tursun, B. and Schlueter, A. and Peters, M.A. and Viehweger, B. and Ostendorff, H.P. and Soosairajah, J. and Drung, A. and Bossenz, M. and Johnsen, S.A. and Schweizer, M. and Bernard, O. and Bach, I.
Genes & Development 19 (19): 2307-2319. 1 October 2005

Mitochondrial signal peptidases of yeast: the rhomboid peptidase Pcp1 and its substrate cytochrome C peroxidase.
Michaelis, G. and Esser, K. and Tursun, B. and Stohn, J.P. and Hanson, S. and Pratje, E.
Gene 354 : 58-63. 18 July 2005

2003

Comparing protein stabilities during zebrafish embryogenesis.
Becker, T. and Bossenz, M. and Tursun, B. and Schlueter, A. and Peters, M.A. and Becker, C.G. and Ostendorff, H.P. and Bach, I.
Methods in Cell Science 25 (1-2): 85-89. 2003

2002

A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1.
Esser, K. and Tursun, B. and Ingenhoven, M. and Michaelis, G. and Pratje, E.
Journal of Molecular Biology 323 (5): 835-843. 8 November 2002