Browse by Research Team

2023

Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J., Sundaravinayagam, D., Blume, A., Marg, A., Grunwald, S., Metzler, E., Escobar, H., Müthel, S., Wang, H., Wollersheim, T., Weber-Carstens, S., Akalin, A., Di Virgilio, M., Tursun, B. and Spuler, S.
International Journal of Molecular Sciences 24 (3): 2772. 1 February 2023

2022

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G., Blume, A., Demirel, F.G., Bulut, S., Popp, O., Mertins, P. and Tursun, B.
Biotechniques 73 (1): 5-17. June 2022

Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G., Popp, O., Mertins, P. and Tursun, B.
Biotechniques 72 (5): 175-184. May 2022

2021

Induced neurons from germ cells in Caenorhabditis elegans.
Marchal, I. and Tursun, B.
Frontiers in Neuroscience 15 : 771687. 3 December 2021

The C. elegans pseudogene sspt-16 (F55A3.7) is required to safeguard germ cells against reprogramming.
Ofenbauer, A., Kraus, C.M. and Tursun, B.
microPublication Biology 2021 18 May 2021

The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M., Farré i Díaz, C., Ofenbauer, A., Herzog, S. and Tursun, B.
Nucleic Acids Research 49 (4): e22. 26 February 2021

2020

Conversion of germ cells to somatic cell types in C. elegans.
ul Fatima, N. and Tursun, B.
Journal of Developmental Biology 8 (4): 24. December 2020

The CONDOR pipeline for simultaneous knockdown of multiple genes identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M., Díaz, C.F., Ofenbauer, A. and Tursun, B.
bioRxiv : 2020.09.01.276972. 1 September 2020

Epigenetic chaperoning of aging.
Müthel, S. and Tursun, B.
Aging 12 (2): 1044-1046. 31 January 2020

2019

Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A., Sengul, T.G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M.H., Ofenbauer, A., Gesell-Salazar, M., Balogh, A., Kempa, S., Tursun, B., Robbins, C.T., Völker, U., Chen, W., Nelson, L. and Gotthardt, M.
Scientific Reports 9 (1): 19976. 27 December 2019

Strategies for in vivo reprogramming.
Ofenbauer, A. and Tursun, B.
Current Opinion in Cell Biology 61 : 9-15. December 2019

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S., Uyar, B., He, M., Krause, A., Vitrinel, B., Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S., Akalin, A. and Tursun, B.
Aging Cell 18 (6): e13012. December 2019

CRISPR-activation-based screen reveals neuronal fate promotion by polycomb repressive complex 2 during direct reprogramming.
Wolfram, T. and Tursun, B.
Stem Cell Investigation 6 : 32. September 2019

HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K., Franke, V., Uyar, B., Wurmus, R., Bulut, S., Tursun, B. and Akalin, A.
Nucleic Acids Research : gkz460. 20 June 2019

Caenorhabditis elegans and systems biology - it is 'systems' all the way down!
Dupuy, D. and Tursun, B.
Current Opinion in Systems Biology 13 : iv-vi. February 2019

MRG-1/MRG15 is a barrier for germ cell to neuron reprogramming in Caenorhabditis elegans.
Hajduskova, M., Baytek, G., Kolundzic, E., Gosdschan, A., Kazmierczak, M., Ofenbauer, A., Beato del Rosal, M.L., Herzog, S., ul Fatima, N., Mertins, P., Seelk-Müthel, S. and Tursun, B.
Genetics 211 (1): 121-139. 1 January 2019

2018

Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M., Karabacak, A., Glahs, A., Kolundzic, E., Hirsekorn, A., Carda, A., Tursun, B., Zinzen, R.P., Lacadie, S.A. and Ohler, U.
Nature Communications 9 (1): 4472. 26 October 2018

Transdifferentiation: do transition states lie on the path of development?
Reid, A. and Tursun, B.
Current Opinion in Systems Biology 11 : 18-23. October 2018

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E., Ofenbauer, A., Bulut, S.I., Uyar, B., Baytek, G., Sommermeier, A., Seelk, S., He, M., Hirsekorn, A., Vucicevic, D., Akalin, A., Diecke, S., Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

The UNC-83/UNC-84 LINC members are required for body wall muscle nuclei positioning in C. elegans.
Ofenbauer, A. and Tursun, B.
Matters Select 31 May 2018

Application of RNAi and heat-shock-induced transcription factor expression to reprogram germ cells to neurons in C. elegans.
Kolundzic, E., Seelk, S. and Tursun, B.
Journal of Visualized Experiments (131): e56889. 1 January 2018

2017

Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans.
Wilhelm, T., Byrne, J., Medina, R., Kolundžić, E., Geisinger, J., Hajduskova, M., Tursun, B. and Richly, H.
Genes & Development 31 (15): 1561-1572. 1 August 2017

PcG proteins in caenorhabditis elegans.
Tursun, B.
In: Polycomb Group Proteins. Translational Epigenetics Series . Elsevier / Academic Press, Amsterdam, 289-315. ISBN 978-0-12-809737-3 6 January 2017

2016

G-quadruplex prediction in E. coli genome reveals a conserved putative G-quadruplex-hairpin-duplex switch.
Kaplan, O.I., Berber, B., Hekim, N. and Doluca, O.
Nucleic Acids Research 44 (19): 9083-9095. 2 November 2016

Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons.
Seelk, S., Adrian-Kalchhauser, I., Hargitai, B., Hajduskova, M., Gutnik, S., Tursun, B. and Ciosk, R.
eLife 5 : e15477. 7 September 2016

A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large.
Waaijers, S., Muñoz, J., Berends, C., Ramalho, J.J., Goerdayal, S.S., Low, T.Y., Zoumaro-Djayoon, A.D., Hoffmann, M., Koorman, T., Tas, R.P., Harterink, M., Seelk, S., Kerver, J., Hoogenraad, C.C., Bossinger, O., Tursun, B., van den Heuvel, S., Heck, A.J.R. and Boxem, M.
BMC Biology 14 (1): 66. 9 August 2016

2014

Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1.
Cochella, L., Tursun, B., Hsieh, Y.W., Galindo, S., Johnston, R.J., Chuang, C.F. and Hobert, O.
Genes & Development 28 (1): 34-43. 1 January 2014

2013

Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain.
Cevik, S., Sanders, A.A.W.M., Van Wijk, E., Boldt, K., Clarke, L., van Reeuwijk, J., Hori, Y., Horn, N., Hetterschijt, L., Wdowicz, A., Mullins, A., Kida, K., Kaplan, O.I., van Beersum, S.E.C., Man Wu, K., Letteboer, S.J.F., Mans, D.A., Katada, T., Kontani, K., Ueffing, M., Roepman, R., Kremer, H. and Blacque, O.E.
PLoS Genetics 9 (12): e1003977. December 2013

ECM modulated early kidney development in embryonic organ culture.
Sebinger, D.D., Ofenbauer, A., Gruber, P., Malik, S. and Werner, C.
Biomaterials 34 (28): 6670-6682. September 2013

2012

Removal of polycomb repressive complex 2 makes C. elegans germ cells susceptible to direct conversion into specific somatic cell types.
Patel, T., Tursun, B., Rahe, D.P. and Hobert, O.
Cell Reports 2 (5): 1178-1186. 29 November 2012

Cellular reprogramming processes in Drosophila and C. elegans.
Tursun, B.
Current Opinion in Genetics & Development 22 (5): 475-484. October 2012

2011

Direct conversion of C. elegans germ cells into specific neuron types.
Tursun, B., Patel, T., Kratsios, P. and Hobert, O.
Science 331 (6015): 304-308. 21 January 2011

2010

The Groucho ortholog UNC-37 interacts with the short Groucho-like protein LSY-22 to control developmental decisions in C. elegans.
Flowers, E.B., Poole, R.J., Tursun, B., Bashllari, E., Pe'er, I. and Hobert, O.
Development 137 (11): 1799-1805. June 2010

Neuron-type specific regulation of a 3'UTR through redundant and combinatorially acting cis-regulatory elements.
Didiano, D., Cochella, L., Tursun, B. and Hobert, O.
RNA 16 (2): 349-363. February 2010

2009

The C. elegans Tailless/TLX transcription factor nhr-67 controls neuronal identity and left/right asymmetric fate diversification.
Sarin, S., Antonio, C., Tursun, B. and Hobert, O.
Development 136 (17): 2933-2944. September 2009

A toolkit and robust pipeline for the generation of fosmid-based reporter genes in C. elegans.
Tursun, B., Cochella, L., Carrera, I. and Hobert, O.
PLoS ONE 4 (3): e4625. 4 March 2009

Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer.
Johnsen, S.A., Guengoer, C., Prenzel, T., Riethdorf, S., Riethdorf, L., Taniguchi-Ishigaki, N., Rau, T., Tursun, B., Furlow, J.D., Sauter, G., Scheffner, M., Pantel, K., Gannon, F. and Bach, I.
Cancer Research 69 (1): 128-136. 1 January 2009

2007

Proteasomal selection of multiprotein complexes recruited by LIM homeodomain transcription factors.
Guengoer, C., Taniguchi-Ishigaki, N., Ma, H., Drung, A., Tursun, B., Ostendorff, H.P., Bossenz, M., Becker, C.G., Becker, T. and Bach, I.
Proceedings of the National Academy of Sciences of the United States of America 104 (38): 15000-15005. 18 September 2007

2006

Dynamic expression of LIM cofactors in the developing mouse neural tube.
Ostendorff, H.P., Tursun, B., Cornils, K., Schlueter, A., Drung, A., Guengoer, C. and Bach, I.
Developmental Dynamics 235 (3): 786-791. March 2006

2005

The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.
Tursun, B., Schlueter, A., Peters, M.A., Viehweger, B., Ostendorff, H.P., Soosairajah, J., Drung, A., Bossenz, M., Johnsen, S.A., Schweizer, M., Bernard, O. and Bach, I.
Genes & Development 19 (19): 2307-2319. 1 October 2005

Mitochondrial signal peptidases of yeast: the rhomboid peptidase Pcp1 and its substrate cytochrome C peroxidase.
Michaelis, G., Esser, K., Tursun, B., Stohn, J.P., Hanson, S. and Pratje, E.
Gene 354 : 58-63. 18 July 2005

2003

Comparing protein stabilities during zebrafish embryogenesis.
Becker, T., Bossenz, M., Tursun, B., Schlueter, A., Peters, M.A., Becker, C.G., Ostendorff, H.P. and Bach, I.
Methods in Cell Science 25 (1-2): 85-89. 2003

2002

A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1.
Esser, K., Tursun, B., Ingenhoven, M., Michaelis, G. and Pratje, E.
Journal of Molecular Biology 323 (5): 835-843. 8 November 2002