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IFT88 maintains sensory function by localising signalling proteins along Drosophila cilia.
Werner, S. and Okenve-Ramos, P. and Hehlert, P. and Zitouni, S. and Priya, P. and Mendonça, S. and Sporbert, A. and Spalthoff, C. and Göpfert, M.C. and Jana, S.C. and Bettencourt-Dias, M.
Life Science Alliance 7 (5): e202302289. May 2024

Mice with renal-specific alterations 1 of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors.
Myszczyszyn, A. and Popp, O. and Kunz, S. and Sporbert, A. and Jung, S. and Penning, L.C. and Fendler, A. and Mertins, P. and Birchmeier, W.
PLoS ONE 19 (3): e0282938. 21 March 2024

Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer.
Bei, Y. and Brame, Luca and Kirchner, M. and Fritsche-Guenther, R. and Kunz, S. and Bhattacharya, A. and Rusu, M.C. and Gürgen, D. and Dubois, F.P.B. and Köppke, J.K.C. and Proba, J. and Wittstruck, N. and Sidorova, O.A. and Chamorro González, R. and Dorado Garcia, H. and Brückner, L. and Xu, R. and Giurgiu, M. and Rodriguez-Fos, E. and Yu, Q. and Spanjaard, B. and Koche, R.P, and Schmitt, C.A. and Schulte, J.H. and Eggert, A. and Haase, K. and Kirwan, J. and Hagemann, A.I. and Mertins, P. and Dörr, J.R. and Henssen, A.G.
Cancer Discovery 14 (3): 492-507. 1 March 2024

In vitro production of naked mole-rats' blastocysts from non-breeding females using in vitro maturation and intracytoplasmic sperm injection.
Simone, R. and Čižmár, D. and Holtze, S. and Michel, G. and Sporbert, A. and Okolo, C. and Hildebrandt, T.B.
Scientific Reports 13 (1): 22355. 15 December 2023

A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A. and Haenig, C. and Neuendorf, N. and Blanc, E. and Ivanov, A. and Kirchner, M. and Schleumann, P. and Bayraktaroğlu, I. and Richter, M. and Molenda, C.M. and Sporbert, A. and Zenkner, M. and Schnoegl, S. and Suenkel, C. and Schneider, L.S. and Rybak-Wolf, A. and Kochnowsky, B. and Byrne, L.M. and Wild, E.J. and Nielsen, J.E. and Dittmar, G. and Peters, O. and Beule, D. and Wanker, E.E.
Genome Medicine 15 (1): 50. 20 July 2023

LRP2 contributes to planar cell polarity-dependent coordination of motile cilia function.
Bunatyan, L. and Margineanu, A. and Boutin, C. and Montcouquiol, M. and Bachmann, S. and Christensen, E.I. and Willnow, T.E. and Christ, A.
Cell and Tissue Research 392 (2): 535-551. May 2023

Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function.
Geng, S. and Paul, F. and Kowalczyk, I. and Raimundo, S. and Sporbert, A. and Mamo, T.M. and Hammes, A.
Frontiers in Cell and Developmental Biology 11 : 1173688. 7 April 2023

IFNγ binding to extracellular matrix prevents fatal systemic toxicity.
Kemna, J. and Gout, E. and Daniau, L. and Lao, J. and Weißert, K. and Ammann, S. and Kühn, R. and Richter, M. and Molenda, C. and Sporbert, A. and Zocholl, D. and Klopfleisch, R. and Schütz, A. and Lortat-Jacob, H. and Aichele, P. and Kammertoens, T. and Blankenstein, T.
Nature Immunology 24 (3): 414-422. March 2023

15-keto-Prostaglandin E(2) exhibits bioactive role by modulating glomerular cytoarchitecture through EP2/EP4 receptors.
Kourpa, A. and Kaiser-Graf, D. and Sporbert, A. and Philippe, A. and Catar, R. and Rothe, M. and Mangelsen, E. and Schulz, A. and Bolbrinker, J. and Kreutz, R. and Panáková, D.
Life Sciences 310 : 121114. 1 December 2022

TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation.
Tufan, A.B. and Lazarow, K. and Kolesnichenko, M. and Sporbert, A. and von Kries, J.P. and Scheidereit, C.
EMBO Journal 41 (21): e110372. 2 November 2022

A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts.
Jäger, K. and Mensch, J. and Grimmig, M.E. and Neuner, B. and Gorzelniak, K. and Türkmen, S. and Demuth, I. and Hartmann, A. and Hartmann, C. and Wittig, F. and Sporbert, A. and Hermann, A. and Fuellen, G. and Möller, S. and Walter, M.
Science Advances 8 (33): eabk2814. August 2022

Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H. and Dauksaite, V. and Sporbert, A. and Gotthardt, M. and Selbach, M.
Molecular Cell 82 (11): 2069-2083. 2 June 2022

Microglia sense neuronal activity via GABA in the early postnatal hippocampus.
Logiacco, F. and Xia, P. and Georgiev, S.V. and Franconi, C. and Chang, Y.J. and Ugursu, B. and Sporbert, A. and Kühn, R. and Kettenmann, H. and Semtner, M.
Cell Reports 37 (13): 110128. 28 December 2021

An expanded polyproline domain maintains mutant huntingtin soluble in vivo and during aging.
Pigazzini, M.L. and Lawrenz, M. and Margineanu, A. and Kaminski Schierle, G.S. and Kirstein, J.
Frontiers in Molecular Neuroscience 14 : 721749. 15 October 2021

Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Willnow, D. and Benary, U. and Margineanu, A. and Vignola, M.L. and Konrath, F. and Pongrac, I.M. and Karimaddini, Z. and Vigilante, A. and Wolf, J. and Spagnoli, F.M.
Nature 597 (7874): 87-91. 2 September 2021

Identification of disease-relevant modulators of the SHH pathway in the developing brain.
Mecklenburg, N. and Kowalczyk, I. and Witte, F. and Görne, J. and Laier, A. and Mamo, T.M. and Gonschior, H. and Lehmann, M. and Richter, M. and Sporbert, A. and Purfürst, B. and Hübner, N. and Hammes, A.
Development 148 (17): dev199307. September 2021

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. and Grinat, J. and Kosel, F. and Liu, L. and Kunz, S. and Vidal, R.O. and Keil, M. and Haybaeck, J. and Robine, S. and Louvard, D. and Regenbrecht, C. and Sporbert, A. and Sauer, S. and von Eyss, B. and Sigal, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari, F. and Dahlmann, M. and Sporbert, A. and Ciolli Mattioli, C. and Mari, T. and Scholz, F. and Timm, L. and Twamley, S. and Migotti, R. and Walther, W. and Dittmar, G. and Rehm, A. and Stein, U.
Cellular and Molecular Life Sciences 78 (7): 3525-3542. April 2021

Photocaged Hoechst enables subnuclear visualization and cell selective staining of DNA in vivo.
Lämmle, C.A. and Varady, A. and Müller, T.G. and Sturtzel, C. and Riepl, M. and Mathes, B. and Eichhorst, J. and Sporbert, A. and Lehmann, M. and Kräusslich, H.G. and Distel, M. and Broichhagen, J.
ChemBioChem 22 (3): 548-556. 2 February 2021

Collagen organization within the cartilage of TRPV4(-/-) mice studied with two-photon microscopy and polarized second harmonic generation.
Servin-Vences, M.R. and Poole, K. and Sporbert, A. and Lewin, G.R. and Margineanu, A.
Cytometry Part A 97 (5): 504-514. May 2020

Tight junction proteins at the blood-brain barrier: far more than claudin-5.
Berndt, P. and Winkler, L. and Cording, J. and Breitkreuz-Korff, O. and Rex, A. and Dithmer, S. and Rausch, V. and Blasig, R. and Richter, M. and Sporbert, A. and Wolburg, H. and Blasig, I.E. and Haseloff, R.F.
Cellular and Molecular Life Sciences 76 (10): 1987-2002. May 2019

Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage.
Schulz, A. and Müller, N.V. and van de Lest, N.A. and Eisenreich, A. and Schmidbauer, M. and Barysenka, A. and Purfürst, B. and Sporbert, A. and Lorenzen, T. and Meyer, A.M. and Herlan, L. and Witten, A. and Rühle, F. and Zhou, W. and de Heer, E. and Scharpfenecker, M. and Panáková, D. and Stoll, M. and Kreutz, R.
eLife 8 : e42068. 22 March 2019

A new fate mapping system reveals context-dependent random or clonal expansion of microglia.
Tay, T.L. and Mai, D. and Dautzenberg, J. and Fernández-Klett, F. and Lin, G. and Sagar, D.M. and Datta, M. and Drougard, A. and Stempfl, T. and Ardura-Fabregat, A. and Staszewski, O. and Margineanu, A. and Sporbert, A. and Steinmetz, L.M. and Pospisilik, J.A. and Jung, S. and Priller, J. and Grün, D. and Ronneberger, O. and Prinz, M.
Nature Neuroscience 20 (6): 793-803. June 2017

Nuclear translocation of the cardiac L-type calcium channel C-terminus is regulated by sex and 17β-estradiol.
Mahmoodzadeh, S. and Haase, H. and Sporbert, A. and Rharass, T. and Panáková, D. and Morano, I.
Journal of Molecular and Cellular Cardiology 97 : 226-234. August 2016

PCNA appears in two populations of slow and fast diffusion with a constant ratio throughout S-phase in replicating mammalian cells.
Zessin, P.J.M. and Sporbert, A. and Heilemann, M.
Scientific Reports 6 : 18779. 13 January 2016

Automated quantification of hematopoietic cell - stromal cell interactions in histological images of undecalcified bone.
Zehentmeier, S. and Cseresnyes, Z. and Escribano Navarro, J. and Niesner, R.A. and Hauser, A.E.
Journal of Visualized Experiments (98) 8 April 2015

Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
Heinig, K. and Gätjen, M. and Grau, M. and Stache, V. and Anagnostopoulos, I. and Gerlach, K. and Niesner, R.A. and Cseresnyes, Z. and Hauser, A.E. and Lenz, P. and Hehlgans, T. and Brink, R. and Westermann, J. and Dörken, B. and Lipp, M. and Lenz, G. and Rehm, A. and Höpken, U.E.
Cancer Discovery 4 : 1448-1465. December 2014

Highly resolved intravital striped-illumination microscopy of germinal centers.
Cseresnyes, Z. and Oehme, L. and Andresen, V. and Sporbert, A. and Hauser, A.E. and Niesner, R.
Journal of Visualized Experiments (86): e51135. 9 April 2014

Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots.
Sporbert, A. and Cseresnyes, Z. and Heidbreder, M. and Domaing, P. and Hauser, S. and Kaltschmidt, B. and Kaltschmidt, C. and Heilemann, M. and Widera, D.
PLoS ONE 8 (5): e64023. 21 May 2013

Unilateral dampening of Bmp activity by Nodal generates cardiac left-right asymmetry.
Veerkamp, J. and Rudolph, F. and Cseresnyes, Z. and Priller, F. and Otten, C. and Renz, M. and Schaefer, L. and Abdelilah-Seyfried, S.
Developmental Cell 24 (6): 660-667. 25 March 2013

High-resolution intravital microscopy.
Andresen, V. and Pollok, K. and Rinnenthal, J.L. and Oehme, L. and Guenther, R. and Spiecker, H. and Radbruch, H. and Gerhard, J. and Sporbert, A. and Cseresnyes, Z. and Hauser, A.E. and Niesner, R.
PLoS ONE 7 (12): e50915. 14 December 2012

Cell tracking using photoconvertible proteins during zebrafish development.
Lombardo, V.A. and Sporbert, A. and Abdelilah-Seyfried, S.
Journal of Visualized Experiments (67): e4350. 28 September 2012

Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation.
Jerke, U. and Rolle, S. and Dittmar, G. and Bayat, B. and Santoso, S. and Sporbert, A. and Luft, F.C. and Kettritz, R.
Journal of Biological Chemistry 286 (9): 7070-7081. 4 March 2011

Uncoupling the replication machinery: Replication fork progression in the absence of processive DNA synthesis.
Goerisch, S.M. and Sporbert, A. and Stear, J.H. and Grunewald, I. and Nowak, D. and Warbrick, E. and Leonhardt, H. and Cardoso, M.C.
Cell Cycle 7 (13): 1983-1990. 1 July 2008

Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis.
Rohe, M. and Carlo, A.S. and Breyhan, H. and Sporbert, A. and Militz, D. and Schmidt, V. and Wozny, C. and Harmeier, A. and Erdmann, B. and Bales, K.R. and Wolf, S.A. and Kempermann, G. and Paul, S.M. and Schmitz, D. and Bayer, T.A. and Willnow, T.E. and Andersen, O.M.
Journal of Biological Chemistry 283 (21): 14826-14834. 23 May 2008

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1.
Schmidt, V. and Sporbert, A. and Rohe, M. and Reimer, T. and Rehm, A. and Andersen, O.M. and Willnow, T.E.
Journal of Biological Chemistry 282 (45): 32956-32964. 9 November 2007

PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins.
Sporbert, A. and Domaing, P. and Leonhardt, H. and Cardoso, M.C.
Nucleic Acids Research 33 (11): 3521-3528. 21 June 2005

DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters.
Sporbert, A. and Gahl, A. and Ankerhold, R. and Leonhardt, H. and Cardoso, M.C.
Molecular Cell 10 (6): 1355-1365. December 2002

(NO)-N-center dot and oxyradical metabolism in new cell lines of rat brain capillary endothelial cells forming the blood-brain barrier.
Blasig, I.E. and Giese, H. and Schroeter, M.L. and Sporbert, A. and Utepbergenov, D.I. and Buchwalow, I.B. and Neubert, K. and Schoenfelder, G. and Freyer, D. and Schimke, I. and Siems, W.E. and Paul, M. and Haseloff, R.F. and Blasig, R.
Microvascular Research 62 (2): 114-127. 1 January 2001

Dynamics of DNA replication factories in living cells.
Leonhardt, H. and Rahn, H.P. and Weinzierl, P. and Sporbert, A. and Cremer, T. and Zink, D. and Cardoso, M.C.
Journal of Cell Biology 149 (2): 271-279. 17 April 2000

Targeting regulatory factors to intranuclear replication sites.
Leonhardt, H. and Sporbert, A. and Cardoso, M.C.
Critical Reviews in Eukaryotic Gene Expression 10 : 127-133. 1 January 2000

Structure and function in the nucleus: Subnuclear trafficking of DNA replication factors.
Cardoso, M.C. and Sporbert, A. and Leonhardt, H.
Journal of Cellular Biochemistry Suppl. 32-33 : 15-23. 1 January 1999


Advanced light microscopy core facilities: Balancing service, science and career.
Ferrando-May, E. and Hartmann, H. and Reymann, J. and Ansari, N. and Utz, N. and Fried, H.U. and Kukat, C. and Peychl, J. and Liebig, C. and Terjung, S. and Laketa, V. and Sporbert, A. and Weidtkamp-Peters, S. and Schauss, A. and Zuschratter, W. and Avilov, S.
Microscopy Research and Technique 79 (6): 463-479. June 2016


IFT88 transports Gucy2d, a guanylyl cyclase, to maintain sensory cilia function in Drosophila.
Werner, S. and Zitouni, S. and Okenve-Ramos, P. and Mendonça, S. and Sporbert, A. and Spalthoff, C. and Göpfert, M.C. and Jana, S.C. and Bettencourt-Dias, M.
bioRxiv : 2020.12.15.417840. 15 December 2020

Identification of novel disease relevant genetic modifiers affecting the SHH pathway in the developing brain.
Mecklenburg, N. and Kowalczyk, I. and Witte, F. and Görne, J. and Laier, A. and Gonschior, H. and Lehmann, M. and Richter, M. and Sporbert, A. and Purfürst, B. and Hübner, N. and Hammes, A.
bioRxiv : 2020.11.03.366302. 3 November 2020

Quantitative lineage analysis identifies a long-term progenitor niche for the hepato-pancreato-biliary organ system.
Willnow, D. and Benary, U. and Margineanu, A. and Vignola, M.L. and Pongrac, I.M. and Karimaddini, Z. and Vigilante, A. and Wolf, J. and Spagnoli, F.M.
bioRxiv : 2020.08.06.240176. 6 August 2020

This list was generated on Tue May 21 02:24:25 2024 CEST.
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