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2019

Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils.
Fischer, J. and Walter, C. and Tönges, A. and Aleth, H. and Costa Jordão, M.J. and Leddin, M. and Gröning, V. and Erdmann, T. and Lenz, G. and Roth, J. and Vogl, T. and Prinz, M. and Dugas, M. and Jacobsen, I.D. and Rosenbauer, F.
Nature Immunology 20 (5): 546-558. May 2019

2013

PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.
Schönheit, J. and Kuhl, C. and Gebhardt, M.L. and Klett, F.F. and Riemke, P. and Scheller, M. and Huang, G. and Naumann, R. and Leutz, A. and Stocking, C. and Priller, J. and Andrade-Navarro, M.A. and Rosenbauer, F.
Cell Reports 3 (5): 1617-1628. 30 May 2013

Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Staber, P.B. and Zhang, P. and Ye, M. and Welner, R.S. and Nombela-Arrieta, C. and Bach, C. and Kerenyi, M. and Bartholdy, B.A. and Zhang, H. and Alberich-Jorda, M. and Lee, S. and Yang, H. and Ng, F. and Zhang, J. and Leddin, M. and Silberstein, L.E. and Hoefler, G. and Orkin, S.H. and Goettgens, B. and Rosenbauer, F. and Huang, G. and Tenen, D.G.
Molecular Cell 49 (5): 934-946. 7 March 2013

2011

Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S. and Riemke, P. and Schoenheit, J. and Lenze, D. and Stumm, J. and Hoogenkamp, M. and Lagendijk, A. and Heinz, S. and Bonifer, C. and Bakkers, J. and Abdelilah-Seyfried, S. and Hummel, M. and Rosenbauer, F.
Blood 118 (8): 2275-2284. 25 August 2011

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M. and Perrod, C. and Hoogenkamp, M. and Ghani, S. and Assi, S. and Heinz, S. and Wilson, N.K. and Follows, G. and Schoenheit, J. and Vockentanz, L. and Mosamam, A. and Chen, W. and Tenen, D.G. and Westhead, D.R. and Goettgens, B. and Bonifer, C. and Rosenbauer, F.
Blood 117 (10): 2827-2838. 10 March 2011

2010

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.
Werth, M. and Walentin, K. and Aue, A. and Schoenheit, J. and Wuebken, A. and Pode-Shakked, N. and Vilianovitch, L. and Erdmann, B. and Dekel, B. and Bader, M. and Barasch, J. and Rosenbauer, F. and Luft, F.C. and Schmidt-Ott, K.M.
Development 137 (22): 3835-3845. November 2010

Uncovering a unique role for DNA methylation in hematopoietic and leukemic stem cells.
Vockentanz, L. and Broeske, A.M. and Rosenbauer, F.
Cell Cycle 9 (4): 640-641. February 2010

2009

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, A.M. and Vockentanz, L. and Kharazi, S. and Huska, M.R. and Mancini, E. and Scheller, M. and Kuhl, C. and Enns, A. and Prinz, M. and Jaenisch, R. and Nerlov, C. and Leutz, A. and Andrade-Navarro, M.A. and Jacobsen, S.E. and Rosenbauer, F.
Nature Genetics 41 (11): 1207-1215. November 2009

2008

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Ebralidze, A.K. and Guibal, F.C. and Steidl, U. and Zhang, P. and Lee, S. and Bartholdy, B. and Jorda, M.A. and Petkova, V. and Rosenbauer, F. and Huang, G. and Dayaram, T. and Klupp, J. and O'Brien, K.B. and Will, B. and Hoogenkamp, M. and Borden, K.L. and Bonifer, C. and Tenen, D.G.
Genes & Development 22 (15): 2085-2092. 1 August 2008

2007

The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation.
Feinberg, M.W. and Wara, A.K. and Cao, Z. and Lebedeva, M.A. and Rosenbauer, F. and Iwasaki, H. and Hirai, H. and Katz, J.P. and Haspel, R. and Gray, S. and Akashi, K. and Segre, J. and Kaestner, K.H. and Tenen, D.G. and Jain, M.K.
EMBO Journal 26 (18): 4138-4148. 19 September 2007

A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.
Steidl, U. and Steidl, C. and Ebralidze, A. and Chapuy, B. and Han, H.J. and Will, B. and Rosenbauer, F. and Becker, A. and Wagner, K. and Koschmieder, S. and Kobayashi, S. and Costa, D.B. and Schulz, T. and OBrien, K.B. and Verhaak, R.G.W. and Delwel, R. and Haase, D. and Truemper, L. and Krauter, J. and Kohwi-Shigematsu, T. and Griesinger, F. and Tenen, D.G.
Journal of Clinical Investigation 117 (9): 2611-2620. 4 September 2007

Transcription factors in myeloid development: balancing differentiation with transformation.
Rosenbauer, F. and Tenen, D.G.
Nature Reviews Immunology 7 (2): 105-117. February 2007

2006

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.
Steidl, U. and Rosenbauer, F. and Verhaak, R.G.W. and Gu, X. and Ebralidze, A. and Otu, H.H. and Klippel, S. and Steidl, C. and Bruns, I. and Costa, D.B. and Wagner, K. and Aivado, M. and Kobbe, G. and Valk, P.J.M. and Passegue, E. and Libermann, T.A. and Delwel, R. and Tenen, D.G.
Nature Genetics 38 (11): 1269-1277. November 2006

Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
Scheller, M. and Huelsken, J. and Rosenbauer, F. and Taketo, M.M. and Birchmeier, W. and Tenen, D.G. and Leutz, A.
Nature Immunology 7 (10): 1037-1047. October 2006

Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
Wagner, K. and Zhang, P. and Rosenbauer, F. and Drescher, B. and Kobayashi, S. and Radomska, H.S. and Kutok, J.L. and Gilliland, D.G. and Krauter, J. and Tenen, D.G.
Proceedings of the National Academy of Sciences of the United States of America 103 (16): 6338-6343. 18 April 2006

Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
Rosenbauer, F. and Owens, B.M. and Yu, L. and Tumang, J.R. and Steidl, U. and Kutok, J.L. and Clayton, L.K. and Wagner, K. and Scheller, M. and Iwasaki, H. and Liu, C. and Hackanson, B. and Akashi, K. and Leutz, A. and Rothstein, T.L. and Plass, C. and Tenen, D.G.
Nature Genetics 38 (1): 27-37. January 2006

2005

Effect of transcription-factor concentrations on leukemic stem cells.
Rosenbauer, F. and Koschmieder, S. and Steidl, U. and Tenen, D.G.
Blood 106 : 1519-1524. 1 September 2005

Role of transcription factors C/EBPalpha and PU.1 in normal hematopoiesis and leukemia.
Koschmieder, S. and Rosenbauer, F. and Steidl, U. and Owens, B.M. and Tenen, D.G.
International Journal of Hematology 81 : 368-377. 1 June 2005

Potential autoregulation of transcription factor PU.1 by an upstream regulatory element.
Okuno, Y. and Huang, G. and Rosenbauer, F. and Evans, E.K. and Radomska, H.S. and Iwasaki, H. and Akashi, K. and Moreau-Gachelin, F. and Li, Y. and Zhang, P. and Goettgens, B. and Tenen, D.G.
Molecular and Cellular Biology 25 : 2832-2845. 1 April 2005

2004

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.
Rosenbauer, F. and Wagner, K. and Kutok, J.L. and Iwasaki, H. and Le Beau, M.M. and Okuno, Y. and Akashi, K. and Fiering, S. and Tenen, D.G.
Nature Genetics 36 : 624-630. 1 June 2004

pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1.
Rosenbauer, F. and Wagner, K. and Zhang, P. and Knobeloch, K.P. and Iwama, A. and Tenen, D.G.
Blood 103 : 4294-4301. 1 June 2004

This list was generated on Mon Apr 15 02:23:15 2024 CEST.
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