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2018

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D. and Schön, C. and Loddenkemper, C. and Lohneis, P. and Kühl, A.A. and Sommermann, T. and Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

Postnatal DNA demethylation and its role in tissue maturation.
Reizel, Y. and Sabag, O. and Skversky, Y. and Spiro, A. and Steinberg, B. and Bernstein, D. and Wang, A. and Kieckhaefer, J. and Li, C. and Pikarsky, E. and Levin-Klein, R. and Goren, A. and Rajewsky, K. and Kaestner, K.H. and Cedar, H.
Nature Communications 9 (1): 2040. 23 May 2018

Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
Choi, I.K. and Wang, Z. and Ke, Q. and Hong, M. and Qian, Y. and Zhao, X. and Liu, Y. and Kim, H.J. and Ritz, J. and Cantor, H. and Rajewsky, K. and Wucherpfennig, K.W. and Zhang, B.
Proceedings of the National Academy of Sciences of the United States of America 115 (4): E686-E695. January 2018

2017

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
Wong, J.B. and Hewitt, S.L. and Heltemes-Harris, L.M. and Mandal, M. and Johnson, K. and Rajewsky, K. and Koralov, S.B. and Clark, M.R. and Farrar, M.A. and Skok, J.A.
bioRxiv : 214908. 13 November 2017

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.
Varano, G. and Raffel, S. and Sormani, M. and Zanardi, F. and Lonardi, S. and Zasada, C. and Perucho, L. and Petrocelli, V. and Haake, A. and Lee, A.K. and Bugatti, M. and Paul, U. and Van Anken, E. and Pasqualucci, L. and Rabadan, R. and Siebert, R. and Kempa, S. and Ponzoni, M. and Facchetti, F. and Rajewsky, K. and Casola, S.
Nature 546 (7657): 302-306. 8 June 2017

George Klein: 1925-2016.
Rajewsky, K.
National Academy of Sciences (U.S.A.). 28 March 2017

EBI2 is highly expressed in multiple sclerosis lesions and promotes early CNS migration of encephalitogenic CD4 T cells.
Wanke, F. and Moos, S. and Croxford, A.L. and Heinen, A.P. and Gräf, S. and Kalt, B. and Tischner, D. and Zhang, J. and Christen, I. and Bruttger, J. and Yogev, N. and Tang, Y. and Zayoud, M. and Israel, N. and Karram, K. and Reißig, S. and Lacher, S.M. and Reichhold, C. and Mufazalov, I.A. and Ben-Nun, A. and Kuhlmann, T. and Wettschureck, N. and Sailer, A.W. and Rajewsky, K. and Casola, S. and Waisman, A. and Kurschus, F.C.
Cell Reports 18 (5): 1270-1284. 31 January 2017

CRISPR/Cas9-mediated in vitro mutagenesis in GC-like B cells.
Chu, V.T. and Graf, R. and Rajewsky, K.
Methods in Molecular Biology 1623 : 135-145. 2017

Development of mouse model systems of germinal center lymphomas.
Kabrani, E. and Sander, S.
Methods in Molecular Biology 1623 : 233-242. 2017

2016

Mouse model for acute Epstein-Barr virus infection.
Wirtz, T. and Weber, T. and Kracker, S. and Sommermann, T. and Rajewsky, K. and Yasuda, T.
Proceedings of the National Academy of Sciences of the United States of America 113 (48): 13821-13826. 29 November 2016

miRNAs are essential for the regulation of the PI3K/AKT/FOXO pathway and receptor editing during B cell maturation.
Coffre, M. and Benhamou, D. and Riess, D. and Blumenberg, L. and Snetkova, V. and Hines, M.J. and Chakraborty, T. and Bajwa, S. and Jensen, K. and Chong, M.M.W. and Getu, L. and Silverman, G.J. and Blelloch, R. and Littman, D.R. and Calado, D. and Melamed, D. and Skok, J.A. and Rajewsky, K. and Koralov, S.B.
Cell Reports 17 (9): 2271-2285. 22 November 2016

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T. and Graf, R. and Wirtz, T. and Weber, T. and Favret, J. and Li, X. and Petsch, K. and Tran, N.T. and Sieweke, M.H. and Berek, C. and Kühn, R. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (44): 12514-12519. 1 November 2016

TAK1 adaptor proteins TAB2 and TAB3 link the signalosome to B cell receptor-induced IKK activation.
Shinohara, H. and Yasuda, T. and Kurosaki, T.
FEBS Letters 590 (18): 3264-3269. September 2016

A c-Myc/miR17-92/Pten axis controls PI3K-mediated positive and negative selection in B cell development and reconstitutes CD19 deficiency.
Benhamou, D. and Labi, V. and Novak, R. and Dai, I. and Shafir-Alon, S. and Weiss, A. and Gaujoux, R. and Arnold, R. and Shen-Orr, S.S. and Rajewsky, K. and Melamed, D.
Cell Reports 16 (2): 419-431. 12 July 2016

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E. and Herzog, S. and Labi, V. and Yasuda, T. and Köchert, K. and Janz, M. and Villunger, A. and Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5065-5070. 3 May 2016

Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.
Orlanski, S. and Labi, V. and Reizel, Y. and Spiro, A. and Lichtenstein, M. and Levin-Klein, R. and Koralov, S.B. and Skversky, Y. and Rajewsky, K. and Cedar, H. and Bergman, Y.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5018-5023. 3 May 2016

Survival of Igα-deficient mature B cells requires BAFF-R function.
Levit-Zerdoun, E. and Becker, M. and Pohlmeyer, R. and Wilhelm, I. and Maity, P.C. and Rajewsky, K. and Reth, M. and Hobeika, E.
Journal of Immunology 196 (5): 2348-2360. 1 March 2016

miR-23~27~24 clusters control effector T cell differentiation and function.
Cho, S. and Wu, C.J. and Yasuda, T. and Cruz, L.O. and Khan, A.A. and Lin, L.L. and Nguyen, D.T. and Miller, M. and Lee, H.M. and Kuo, M.L. and Broide, D.H. and Rajewsky, K. and Rudensky, A.Y. and Lu, L.F.
Journal of Experimental Medicine 213 (2): 235-249. 8 February 2016

Immunological memory: lessons from the past and a look to the future.
Farber, D.L. and Netea, M.G. and Radbruch, A. and Rajewsky, K. and Zinkernagel, R.M.
Nature Reviews Immunology 16 (2): 124-128. February 2016

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.
Chu, V.T. and Weber, T. and Graf, R. and Sommermann, T. and Petsch, K. and Sack, U. and Volchkov, P. and Rajewsky, K. and Kühn, R.
BMC Biotechnology 16 (1): 4. 16 January 2016

FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm, K. and Happel, K. and Eelen, G. and Schoors, S. and Oellerich, M.F. and Lim, R. and Zimmermann, B. and Aspalter, I.M. and Franco, C.A. and Boettger, T. and Braun, T. and Fruttiger, M. and Rajewsky, K. and Keller, C. and Brüning, J.C. and Gerhardt, H. and Carmeliet, P. and Potente, M.
Nature 529 (7585): 216-220. 14 January 2016

Isolation of eosinophils from the lamina propria of the murine small intestine.
Berek, C. and Beller, A. and Chu, V.T.
Methods in Molecular Biology 1422 : 213-221. 2016

MAP kinase cascades in antigen receptor signaling and physiology.
Yasuda, T.
Current Topics in Microbiology and Immunology 393 : 211-231. 2016

2015

PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones.
Sander, S. and Chu, V.T. and Yasuda, T. and Franklin, A. and Graf, R. and Calado, D.P. and Li, S. and Imami, K. and Selbach, M. and Di Virgilio, M. and Bullinger, L. and Rajewsky, K.
Immunity 43 (6): 1075-1086. 15 December 2015

Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Finkin, S. and Yuan, D. and Stein, I. and Taniguchi, K. and Weber, A. and Unger, K. and Browning, J.L. and Goossens, N. and Nakagawa, S. and Gunasekaran, G. and Schwartz, M.E. and Kobayashi, M. and Kumada, H. and Berger, M. and Pappo, O. and Rajewsky, K. and Hoshida, Y. and Karin, M. and Heikenwalder, M. and Ben-Neriah, Y. and Pikarsky, E.
Nature Immunology 16 (12): 1235-1244. December 2015

The Herzenberg lecture: how to make a B-1 cell?
Rajewsky, K.
Annals of the New York Academy of Sciences 1362 (1): 6-7. December 2015

Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9.
Kühn, R. and Chu, V.T.
Genome Biology 16 (1): 244. 10 November 2015

Gab1 and Mapk signaling are essential in the hair cycle and hair follicle stem cell quiescence.
Akilli Öztürk, Ö. and Pakula, H. and Chmielowiec, J. and Qi, J. and Stein, S. and Lan, L. and Sasaki, Y. and Rajewsky, K. and Birchmeier, W.
Cell Reports 13 (3): 561-572. 20 October 2015

The B-cell antigen receptor integrates adaptive and innate immune signals.
Otipoby, K.L. and Waisman, A. and Derudder, E. and Srinivasan, L. and Franklin, A. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 112 (39): 12145-12150. 29 September 2015

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.
Murakawa, Y. and Hinz, M. and Mothes, J. and Schuetz, A. and Uhl, M. and Wyler, E. and Yasuda, T. and Mastrobuoni, G. and Friedel, C.C. and Dölken, L. and Kempa, S. and Schmidt-Supprian, M. and Blüthgen, N. and Backofen, R. and Heinemann, U. and Wolf, J. and Scheidereit, C. and Landthaler, M.
Nature Communications 6 : 7367. 14 July 2015

A rapid embryonic stem cell-based mouse model for B-cell lymphomas driven by Epstein-Barr virus protein LMP1.
Ba, Z. and Meng, F.L. and Gostissa, M. and Huang, P.Y. and Ke, Q. and Wang, Z. and Dao, M.N. and Fujiwara, Y. and Rajewsky, K. and Zhang, B. and Alt, F.W.
Cancer Immunology Research 3 (6): 641-649. June 2015

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression.
Zhang, B. and Calado, D.P. and Wang, Z. and Froehler, S. and Koechert, K. and Qian, Y. and Koralov, S.B. and Schmidt-Supprian, M. and Sasaki, Y. and Unitt, C. and Rodig, S. and Chen, W. and Dalla-Favera, R. and Alt, F.W. and Pasqualucci, L. and Rajewsky, K.
Cell Reports 11 (5): 715-726. 5 May 2015

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu, V.T. and Weber, T. and Wefers, B. and Wurst, W. and Sander, S. and Rajewsky, K. and Kühn, R.
Nature Biotechnology 33 (5): 543-548. May 2015

How cell death shapes cancer.
Labi, V. and Erlacher, M.
Cell Death & Disease 6 : e1675. 5 March 2015

The DNA deamination model of somatic antibody diversification.
Rajewsky, K.
Journal of Immunology 194 (5): 2041-2042. 1 March 2015

VH replacement in primary immunoglobulin repertoire diversification.
Sun, A. and Novobrantseva, T.I. and Coffre, M. and Hewitt, S.L. and Jensen, K. and Skok, J.A. and Rajewsky, K. and Koralov, S.B.
Proceedings of the National Academy of Sciences of the United States of America 112 (5): E458-E466. 3 February 2015

TET proteins and 5-methylcytosine oxidation in hematological cancers.
Ko, M. and An, J. and Pastor, W.A. and Koralov, S.B. and Rajewsky, K. and Rao, A.
Immunological Reviews 263 (1): 6-21. January 2015

Roles of MicroRNAs in B lymphocyte physiology and oncogenesis.
Muljo, S.A. and Rajewsky, K.
In: Molecular Biology of B Cells. Academic Press, 65-73. ISBN 978-0-12-397933-9 2015

2014

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S. and Bouhlel, M.A. and Cauchy, P. and Lamprecht, B. and Li, S. and Grau, M. and Hummel, F. and Köchert, K. and Anagnostopoulos, I. and Jöhrens, K. and Hummel, M. and Hiscott, J. and Wenzel, S.S. and Lenz, P. and Schneider, M. and Küppers, R. and Scheidereit, C. and Giefing, M. and Siebert, R. and Rajewsky, K. and Lenz, G. and Cockerill, P.N. and Janz, M. and Dörken, B. and Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111 (42): E4513-E4522. 21 October 2014

IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors.
Authier, H. and Billot, K. and Derudder, E. and Bordereaux, D. and Riviere, P. and Rodrigues-Ferreira, S. and Nahmias, C. and Baud, V.
Proceedings of the National Academy of Sciences of the United States of America 111 (41): 14794-14799. 14 October 2014

STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis.
Backert, I. and Koralov, S.B. and Wirtz, S. and Kitowski, V. and Billmeier, U. and Martini, E. and Hofmann, K. and Hildner, K. and Wittkopf, N. and Brecht, K. and Waldner, M. and Rajewsky, K. and Neurath, M.F. and Becker, C. and Neufert, C.
Journal of Immunology 193 (7): 3779-3791. 1 October 2014

B cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.
Hojer, C. and Frankenberger, S. and Strobl, L.J. and Feicht, S. and Djermanovic, K. and Jagdhuber, F. and Hömig-Hölzel, C. and Ferch, U. and Ruland, J. and Rajewsky, K. and Zimber-Strobl, U.
Cancer Research 74 (16): 4318-4328. 15 August 2014

Generation of memory B cells inside and outside germinal centers.
Takemori, T. and Kaji, T. and Takahashi, Y. and Shimoda, M. and Rajewsky, K.
European Journal of Immunology 44 (5): 1258-1264. May 2014

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J. and Kosel, F. and Qi, J. and Grossmann, K.S. and Rajewsky, K. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 111 (9): 3472-3477. 4 March 2014

Michael S. Neuberger 1953-2013.
Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 111 (8): 2862-2863. 25 February 2014

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E. and McShane, E. and Cheret, C. and Walcher, J. and Müller, T. and Wulf-Goldenberg, A. and Hoelper, S. and Garratt, A.N. and Krüger, M. and Rajewsky, K. and Meijer, D. and Birchmeier, W. and Lewin, G.R. and Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

2013

Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice.
Yasuda, T. and Wirtz, T. and Zhang, B. and Wunderlich, T. and Schmidt-Supprian, M. and Sommermann, T. and Rajewsky, K.
Cold Spring Harbor Symposia on Quantitative Biology 78 : 259-263. 15 November 2013

T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia.
Fogli, L.K. and Sundrud, M.S. and Goel, S. and Bajwa, S. and Jensen, K. and Derudder, E. and Sun, A. and Coffre, M. and Uyttenhove, C. and Van Snick, J. and Schmidt-Supprian, M. and Rao, A. and Grunig, G. and Durbin, J. and Casola, S.S. and Rajewsky, K. and Koralov, S.B.
Journal of Immunology 191 (6): 3100-3111. 15 September 2013

Inflammation in mice ectopically expressing human PAPA syndrome-associated PSTPIP1 A230T mutant proteins.
Wang, D. and Höing, S. and Patterson, H.C. and Ahmad, U.M. and Rathinam, V.A.K. and Rajewsky, K. and Fitzgerald, K.A. and Golenbock, D.T.
Journal of Biological Chemistry 288 (7): 4594-4601. 15 February 2013

2012

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P. and Sasaki, Y. and Godinho, S.A. and Pellerin, A. and Koechert, K. and Sleckman, B.P. and de Alboran, I.M. and Janz, M. and Rodig, S. and Rajewsky, K.
Nature Immunology 13 (11): 1092-1100. November 2012

Burkitt lymphomagenesis linked to MYC plus PI3K in germinal center B cells.
Sander, S. and Rajewsky, K.
Oncotarget 3 (10): 1066-1067. 28 October 2012

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
Kaji, T. and Ishige, A. and Hikida, M. and Taka, J. and Hijikata, A. and Kubo, M. and Nagashima, T. and Takahashi, Y. and Kurosaki, T. and Okada, M. and Ohara, O. and Rajewsky, K. and Takemori, T.
Journal of Experimental Medicine 209 (11): 2079-2097. 22 October 2012

Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.
Sander, S. and Calado, D.P. and Srinivasan, L. and Koechert, K. and Zhang, B. and Rosolowski, M. and Rodig, S.J. and Holzmann, K. and Stilgenbauer, S. and Siebert, R. and Bullinger, L. and Rajewsky, K.
Cancer Cell 22 (2): 167-179. 14 August 2012

Immune surveillance and therapy of lymphomas driven by Epstein-Barr-Virus protein LMP1 in a mouse model.
Zhang, B. and Kracker, S. and Yasuda, T. and Casola, S. and Vannemann, M. and Hoemig-Hoeltzel, C. and Wang, Z. and Derudder, E. and Li, S. and Chakraborty, T. and Cotter, S.E. and Koyama, S. and Currie, T. and Freeman, G.J. and Kutok, J.L. and Rodig, S.J. and Dranoff, G. and Rajewsky, K.
Cell 148 (4): 739-751. 17 February 2012

2011

Efficient generation of B lymphocytes by recognition of self-antigens.
Eschbach, C. and Bach, M.P. and Fidler, I. and Pelanda, R. and Koehler, F. and Rajewsky, K. and Jumaa, H.
European Journal of Immunology 41 (8): 2397-2403. August 2011

2010

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma.
Calado, D.P. and Zhang, B. and Srinivasan, L. and Sasaki, Y. and Seagal, J. and Unitt, C. and Rodig, S. and Kutok, J. and Tarakhovsky, A. and Schmidt-Supprian, M. and Rajewsky, K.
Cancer Cell 18 (6): 580-589. 14 December 2010

Regulation of microRNA expression and abundance during lymphopoiesis.
Kuchen, S. and Resch, W. and Yamane, A. and Kuo, N. and Li, Z. and Chakraborty, T. and Wei, L. and Laurence, A. and Yasuda, T. and Peng, S. and Hu-Li, J. and Lu, K. and Dubois, W. and Kitamura, Y. and Charles, N. and Sun, H.W. and Muljo, S. and Schwartzberg, P.L. and Paul, W.E. and O'Shea, J. and Rajewsky, K. and Casellas, R.
Immunity 32 (6): 828-839. 25 June 2010

2009

PI3 kinase signals BCR-dependent mature B cell survival.
Srinivasan, L. and Sasaki, Y. and Calado, D.P. and Zhang, B. and Paik, J.H. and DePinho, R.A. and Kutok, J.L. and Kearney, J.F. and Otipoby, K.L. and Rajewsky, K.
Cell 139 (3): 573-586. 30 October 2009

MicroRNA control in the immune system: basic principles.
Xiao, C. and Rajewsky, K.
Cell 136 (1): 26-36. 9 January 2009

This list was generated on Sat Sep 22 02:22:08 2018 CEST.
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