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Article

iSuRe-HadCre is an essential tool for effective conditional genetics.
Garcia-Gonzalez, I., Rocha, S.F., Hamidi, A., Garcia-Ortega, L., Regano, A., Sanchez-Muñoz, M.S., Lytvyn, M., Garcia-Cabero, A., Roig-Soucase, S., Schoofs, H., Castro, M., Sabata, H., Potente, M., Graupera, M., Makinen, T. and Benedito, R.
Nucleic Acids Research : gkae472. 8 June 2024 (In Press)

PI3K-C2β limits mTORC1 signaling and angiogenic growth.
Kobialka, P., Llena, J., Deleyto-Seldas, N., Munar-Gelabert, M., Dengra, J.A., Villacampa, P., Albinyà-Pedrós, A., Muixi, L., Andrade, J., van Splunder, H., Angulo-Urarte, A., Potente, M., Grego-Bessa, J., Castillo, S.D., Vanhaesebroeck, B., Efeyan, A. and Graupera, M.
Science Signaling 16 (813): eadg1913. November 2023

Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Li, X., Wu, F., Günther, S., Looso, M., Kuenne, C., Zhang, T., Wiesnet, M., Klatt, S., Zukunft, S., Fleming, I., Poschet, G., Wietelmann, A., Atzberger, A., Potente, M., Yuan, X. and Braun, T.
Nature 622 (7983): 619-626. 19 October 2023

Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2.
Li, R., Shao, J., Jin, Y.J., Kawase, H., Ong, Y.T., Troidl, K., Quan, Q., Wang, L., Bonnavion, R., Wietelmann, A., Helmbacher, F., Potente, M., Graumann, J., Wettschureck, N. and Offermanns, S.
Nature Communications 14 (1): 1980. 8 April 2023

Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine.
Wu, F., Li, X., Looso, M., Liu, H., Ding, D., Günther, S., Kuenne, C., Liu, S., Weissmann, N., Boettger, T., Atzberger, A., Kolahian, S., Renz, H., Offermanns, S., Gärtner, U., Potente, M., Zhou, Y., Yuan, X. and Braun, T.
Nature Genetics 55 (1): 100-111. January 2023

Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics.
Ferrante, F., Giaimo, B.D., Friedrich, T., Sugino, T., Mertens, D., Kugler, S., Gahr, B.M., Just, S., Pan, L., Bartkuhn, M., Potente, M., Oswald, F. and Borggrefe, T.
Cell Death & Disease 13 (7): 600. 12 July 2022

A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth.
Ong, Y.T., Andrade, J., Armbruster, M., Shi, C., Castro, M., Costa, A.S.H., Sugino, T., Eelen, G., Zimmermann, B., Wilhelm, K., Lim, J., Watanabe, S., Guenther, S., Schneider, A., Zanconato, F., Kaulich, M., Pan, D., Braun, T., Gerhardt, H., Efeyan, A., Carmeliet, P., Piccolo, S., Grosso, A.R. and Potente, M.
Nature Metabolism 4 (6): 672-682. June 2022

Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load.
Kaneshige, A., Kaji, T., Zhang, L., Saito, H., Nakamura, A., Kurosawa, T., Ikemoto-Uezumi, M., Tsujikawa, K., Seno, S., Hori, M., Saito, Y., Matozaki, T., Maehara, K., Ohkawa, Y., Potente, M., Watanabe, S., Braun, T., Uezumi, A. and Fukada, S.I.
Cell Stem Cell 29 (2): 265-280. 3 February 2022

Locus-conserved circular RNA cZNF292 controls endothelial cell flow responses.
Heumüller, A.W., Jones, A. N., Mourão, A., Klangwart, M., Shi, C., Wittig, I., Fischer, A., Muhly Reinholz, M., Buchmann, G.K., Dieterich, C., Potente, M., Braun, T., Grote, P., Jaé, N., Sattler, M. and Dimmeler, S.
Circulation Research 130 (1): 67-79. 7 January 2022

Regional specialization and fate specification of bone stromal cells in skeletal development.
Sivaraj, K.K., Jeong, H.W., Dharmalingam, B., Zeuschner, D., Adams, S., Potente, M. and Adams, R.H.
Cell Reports 36 (2): 109352. 13 July 2021

Post-myocardial infarction heart failure dysregulates the bone vascular niche.
Hoffmann, J., Luxán, G., Abplanalp, W.T., Glaser, S.F., Rasper, T., Fischer, A., Muhly-Reinholz, M., Potente, M., Assmus, B., John, D., Zeiher, A.M. and Dimmeler, S.
Nature Communications 12 (1): 3964. 25 June 2021

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren, A.A., Snellings, D.A., Su, Y.S., Hong, C.C., Castro, M., Tang, A.T., Detter, M.R., Hobson, N., Girard, R., Romanos, S., Lightle, R., Moore, T., Shenkar, R., Benavides, C., Beaman, M.M., Mueller-Fielitz, H., Chen, M., Mericko, P., Yang, J., Sung, D.C., Lawton, M.T., Ruppert, M., Schwaninger, M., Körbelin, J., Potente, M., Awad, I.A., Marchuk, D.A. and Kahn, M.L.
Nature 594 (7862): :271-276. 10 June 2021

Control of endothelial quiescence by FOXO-regulated metabolites.
Andrade, J., Shi, C., Costa, A.S.H., Choi, J., Kim, J., Doddaballapur, A., Sugino, T., Ong, Y.T., Castro, M., Zimmermann, B., Kaulich, M., Guenther, S., Wilhelm, K., Kubota, Y., Braun, T., Koh, G.Y., Grosso, A.R., Frezza, C. and Potente, M.
Nature Cell Biology 23 : 413-423. April 2021

Arterialization requires the timely suppression of cell growth.
Luo, W., Garcia-Gonzalez, I., Fernández-Chacón, M., Casquero-Garcia, V., Sanchez-Muñoz, M.S., Mühleder, S., Garcia-Ortega, L., Andrade, J., Potente, M. and Benedito, R.
Nature 589 (7842): 437-441. 21 January 2021

11,12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by down-regulating p27(Kip1).
Potente, M., Fisslthaler, B., Busse, R. and Fleming, I.
Journal of Biological Chemistry 278 (32): 29619-29625. 4 January 2021

Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1.
Potente, M., Michaelis, U.R., Fisslthaler, B., Busse, R. and Fleming, I.
Journal of Biological Chemistry 277 (18): 15671-15676. 4 January 2021

YAP and TAZ protect against white adipocyte cell death during obesity.
Wang, L., Wang, S.P., Shi, Y., Li, R., Günther, S., Ong, Y.T., Potente, M., Yuan, Z., Liu, E. and Offermanns, S.
Nature Communications 11 (1): 5455. 28 October 2020

Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state.
Helker, C.S.M., Eberlein, J., Wilhelm, K., Sugino, T., Malchow, J., Schuermann, A., Baumeister, S., Kwon, H.B., Maischein, H.M., Potente, M., Herzog, W. and Stainier, D.Y.R.
eLife 9 : e55589. 21 September 2020

Metabolic modulation regulates cardiac wall morphogenesis in zebrafish.
Fukuda, R., Aharonov, A., Ong, Y.T., Stone, O.A., El-Brolosy, M., Maischein, H.M., Potente, M., Tzahor, El. and Stainier, D.Y.R.
eLife 8 23 December 2019

Deubiquitinase USP10 regulates Notch signaling in the endothelium.
Lim, R., Sugino, T., Nolte, H., Andrade, J., Zimmermann, B., Shi, C., Doddaballapur, A., Ong, Y.T., Wilhelm, K., Fasse, J.W.D., Ernst, A., Kaulich, M., Husnjak, K., Boettger, T., Guenther, S., Braun, T., Krüger, M., Benedito, R., Dikic, I. and Potente, M.
Science 364 (6436): 188-193. 12 April 2019

aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability.
Riddell, M., Nakayama, A., Hikita, T., Mirzapourshafiyi, F., Kawamura, T., Pasha, A., Li, M., Masuzawa, M., Looso, M., Steinbacher, T., Ebnet, K., Potente, M., Hirose, T., Ohno, S., Fleming, I., Gattenlöhner, S., Aung, P.P., Phung, T., Yamasaki, O., Yanagi, T., Umemura, H. and Nakayama, M.
Nature Communications 9 (1): 5357. 17 December 2018

Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.
Stone, O.A., El-Brolosy, M., Wilhelm, K., Liu, X., Romão, A.M., Grillo, E., Lai, J.K.H., Günther, S., Jeratsch, S., Kuenne, C., Lee, I.C., Braun, T., Santoro, M.M., Locasale, J.W., Potente, M. and Stainier, D.Y.R.
Nature Communications 9 (1): 4077. 9 October 2018

Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system.
Herz, K., Becker, A., Shi, C., Ema, M., Takahashi, S., Potente, M., Hesse, M., Fleischmann, B.K. and Wenzel, D.
Angiogenesis 21 (2): 349-361. May 2018

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development.
Neto, F., Klaus-Bergmann, A., Ong, Y.T., Alt, S., Vion, A.C., Szymborska, A., Carvalho, J.R., Hollfinger, I., Bartels-Klein, E., Franco, C.A., Potente, M. and Gerhardt, H.
eLife 7 : e31037. 5 February 2018

FGF-dependent metabolic control of vascular development.
Yu, P., Wilhelm, K., Dubrac, A., Tung, J.K., Alves, T.C., Fang, J.S., Xie, Y., Zhu, Ji., Chen, Z., De Smet, F., Zhang, J., Jin, S.W., Sun, L., Sun, H., Kibbey, R.G., Hirschi, K.K., Hay, N., Carmeliet, P., Chittenden, T.W., Eichmann, A., Potente, M. and Simons, M.
Nature 545 (7653): 224-228. 11 May 2017

Metabolische Regulation des Blutgefäßwachstums [Metabolic regulation of blood vessel growth].
Wilhelm, K. and Potente, M.
BIOspektrum 22 (6): 597-599. 2 October 2016

FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M.F., Lim, R., Zimmermann, B., Aspalter, I.M., Franco, C.A., Boettger, T., Braun, T., Fruttiger, M., Rajewsky, K., Keller, C., Brüning, J.C., Gerhardt, H., Carmeliet, P. and Potente, M.
Nature 529 (7585): 216-220. 14 January 2016

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Serra, H., Chivite, I., Angulo-Urarte, A., Soler, A., Sutherland, J.D., Arruabarrena-Aristorena, A., Ragab, A., Lim, R., Malumbres, M., Fruttiger, M., Potente, M., Serrano, M., Fabra, A., Vinals, F., Casanovas, O., Pandolfi, P.P., Bigas, A., Carracedo, A., Gerhardt, H. and Graupera, M.
Nature Communications 6 : 7935. 31 July 2015

Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy.
Domigan, C.K., Warren, C.M., Antanesian, V., Happel, K., Ziyad, S., Lee, S., Krall, A., Duan, L., Torres-Collado, A.X., Castellani, L.W., Elashoff, D., Christofk, H.R., van der Bliek, A.M., Potente, M. and Iruela-Arispe, M.L.
Journal of Cell Science 128 (12): 2236-2248. 15 June 2015

Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3.
Doddaballapur, A., Michalik, K.M., Manavski, Y., Lucas, T., Houtkooper, R.H., You, X., Chen, W., Zeiher, A.M., Potente, M., Dimmeler, S. and Boon, R.A.
Arteriosclerosis Thrombosis and Vascular Biology 35 (1): 137-145. January 2015

PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7.
Martin, M., Geudens, I., Bruyr, J., Potente, M., Bleuart, A., Lebrun, M., Simonis, N., Deroanne, C., Twizere, J.C., Soubeyran, P., Peixoto, P., Mottet, D., Janssens, V., Hofmann, W.K., Claes, F., Carmeliet, P., Kettmann, R., Gerhardt, H. and Dequiedt, F.
EMBO Journal 32 (18): 2491-2503. 11 September 2013

The polarity protein Scrib is essential for directed endothelial cell migration.
Michaelis, U.R., Chavakis, E., Kruse, C., Jungblut, B., Kaluza, D., Wandzioch, K., Manavski, Y., Heide, H., Santoni, M.J., Potente, M., Eble, J.A., Borg, J.P. and Brandes, R.P.
Circulation Research 112 (6): 924-934. 15 March 2013

MicroRNA-34a regulates cardiac ageing and function.
Boon, R.A., Iekushi, K., Lechner, S., Seeger, T., Fischer, A., Heydt, S., Kaluza, D., Tréguer, K., Carmona, G., Bonauer, A., Horrevoets, A.J.G., Didier, N., Girmatsion, Z., Biliczki, P., Ehrlich, J.R., Katus, H.A., Müller, O.J., Potente, M., Zeiher, A.M., Hermeking, H. and Dimmeler, S.
Nature 495 (7439): 107-110. 7 March 2013

Venoarterielle ECMO als "bridge to recovery": Kardiogener Schock und Verdacht auf Myokarditis bei einer 37-Jährigen [Veno-arterial ECMO as bridge to recovery. Cardiogenic shock and suspected myocarditis in a 37-year-old patient].
Fox, H., Seeger, F.H., Schmitt, J., Potente, M., Dzemali, O., Fichtlscherer, S. and Ehrlich, J.R.
Medizinische Klinik, Intensivmedizin und Notfallmedizin 107 (3): 206-212. April 2012

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase.
Guarani, V., Deflorian, G., Franco, C.A., Krüger, M., Phng, L.K., Bentley, K., Toussaint, L., Dequiedt, F., Mostoslavsky, R., Schmidt, M.H.H., Zimmermann, B., Brandes, R.P., Mione, M., Westphal, C.H., Braun, T., Zeiher, A.M., Gerhardt, H., Dimmeler, S. and Potente, M.
Nature 473 (7346): 234-238. 12 May 2011

MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice.
Bonauer, A., Carmona, G., Iwasaki, M., Mione, M., Koyanagi, M., Fischer, A., Burchfield, J., Fox, H., Doebele, C., Ohtani, K., Chavakis, E., Potente, M., Tjwa, M., Urbich, C., Zeiher, A.M. and Dimmeler, S.
Science 324 (5935): 1710-1713. 26 June 2009

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.
Urbich, C., Rössig, L., Kaluza, D., Potente, M., Boeckel, J.N., Knau, A., Diehl, F., Geng, J.G., Hofmann, W.K., Zeiher, A.M. and Dimmeler, S.
Blood 113 (22): 5669-5679. 28 May 2009

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.
Phng, L.K., Potente, M., Leslie, J.D., Babbage, J., Nyqvist, D., Lobov, I., Ondr, J.K., Rao, S., Lang, R.A., Thurston, G. and Gerhardt, H.
Developmental Cell 16 (1): 70-82. 20 January 2009

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.
Taddei, A., Giampietro, C., Conti, A., Orsenigo, F., Breviario, F., Pirazzoli, V., Potente, M., Daly, C., Dimmeler, S. and Dejana, E.
Nature Cell Biology 10 (8): 923-934. August 2008

Emerging roles of SIRT1 in vascular endothelial homeostasis.
Potente, M. and Dimmeler, S.
Cell Cycle 7 (14): 2117-2122. 15 July 2008

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis.
Martin, M., Potente, M., Janssens, V., Vertommen, D., Twizere, J.C., Rider, M.H., Goris, J., Dimmeler, S., Kettmann, R. and Dequiedt, F.
Proceedings of the National Academy of Sciences of the United States of America 105 (12): 4727-4732. 25 March 2008

SIRT1 controls endothelial angiogenic functions during vascular growth.
Potente, M., Ghaeni, L., Baldessari, D., Mostoslavsky, R., Rossig, L., Dequiedt, F., Haendeler, J., Mione, M., Dejana, E., Alt, F.W., Zeiher, A.M. and Dimmeler, S.
Genes & Development 21 (20): 2644-2658. 15 October 2007

Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization.
Potente, M., Urbich, C., Sasaki, K.I., Hofmann, W.K., Heeschen, C., Aicher, A., Kollipara, R., DePinho, R.A., Zeiher, A.M. and Dimmeler, S.
Journal of Clinical Investigation 115 (9): 2382-2392. 1 September 2005

Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells.
Rössig, L., Urbich, C., Brühl, T., Dernbach, E., Heeschen, C., Chavakis, E., Sasaki, K.I., Aicher, D., Diehl, F., Seeger, F., Potente, M., Aicher, A., Zanetta, L., Dejana, E., Zeiher, A.M. and Dimmeler, S.
Journal of Experimental Medicine 201 (11): 1825-35. 6 June 2005

FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells.
Urbich, C., Knau, A., Fichtlscherer, S., Walter, D.H., Brühl, T., Potente, M., Hofmann, W.K., de Vos, S., Zeiher, A.M. and Dimmeler, S.
FASEB Journal 19 (8): 974-976. June 2005

Cytochrome P450 2C is an EDHF synthase in coronary arteries.
Fisslthaler, B., Popp, R., Kiss, L., Potente, M., Harder, D.R., Fleming, I. and Busse, R.
Nature 401 (6752): 493-497. 30 September 1999

Review

Vascular heterogeneity and specialization in development and disease.
Potente, M. and Mäkinen, T.
Nature Reviews Molecular Cell Biology 18 (8): 477-494. August 2017

The link between angiogenesis and endothelial metabolism.
Potente, M. and Carmeliet, P.
Annual Review of Physiology 79 : 43-66. 10 February 2017

Regulation of angiogenesis by PI3K signaling networks.
Graupera, M. and Potente, M.
Experimental Cell Research 319 (9): 1348-1355. 15 May 2013

FOXOs and sirtuins in vascular growth, maintenance, and aging.
Oellerich, M.F. and Potente, M.
Circulation Research 110 (9): 1238-51. 27 April 2012

Basic and therapeutic aspects of angiogenesis.
Potente, M., Gerhardt, H. and Carmeliet, P.
Cell 146 (6): 873-887. 16 September 2011

SIRT1 - a metabolic sensor that controls blood vessel growth.
Guarani, V. and Potente, M.
Current Opinion in Pharmacology 10 (2): 139-145. April 2010

Editorial

The blood-brain barrier-a metabolic ecosystem.
Castro, M. and Potente, M.
EMBO Journal 41 (9): e111189. 2 May 2022

Endothelial cells don't waste: endothelial-derived lactate boosts muscle regeneration.
Castro, M., Andrade, J. and Potente, M.
Developmental Cell 54 (2): 137-139. 20 July 2020

Top-NOTCH regulation of cardiac metabolism.
Lim, R. and Potente, M.
Circulation 137 (24): 2609-2612. 12 June 2018

New Q(ues) to keep blood vessels growing.
Andrade, J. and Potente, M.
EMBO Journal 36 (16): 2315-2317. 15 August 2017

An energy-sensor network takes center stage during endothelial aging.
Potente, M.
Circulation Research 106 (8): 1316-1318. 30 April 2010

NO targets SIRT1: a novel signaling network in endothelial senescence.
Potente, M. and Dimmeler, S.
Arteriosclerosis Thrombosis and Vascular Biology 28 (9): 1577-1579. September 2008

Comment

Endothelial metabolism - more complex (III) than previously thought.
Andrade, J. and Potente, M.
Nature Metabolism 1 (1): 14-15. January 2019

This list was generated on Wed Jul 17 18:08:43 2024 UTC.
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