Browse by Research Team

2021

Overcoming barriers to the adoption of locating technologies in dementia care: a multi-stakeholder focus group study.
Freiesleben, S.D. and Megges, H. and Herrmann, C. and Wessel, L. and Peters, O.
BMC Geriatrics 21 (1): 378. 21 June 2021

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
de Rojas, I. and Moreno-Grau, S. and Tesi, N. and Grenier-Boley, B. and Andrade, V. and Jansen, I.E. and Pedersen, N.L. and Stringa, N. and Zettergren, A. and Hernández, I. and Montrreal, L. and Antúnez, C. and Antonell, A. and Tankard, R.M. and Bis, J.C. and Sims, R. and Bellenguez, C. and Quintela, I. and González-Perez, A. and Calero, M. and Franco-Macías, E. and Macías, J. and Blesa, R. and Cervera-Carles, L. and Menéndez-González, M. and Frank-García, A. and Royo, J.L. and Moreno, F. and Huerto Vilas, R. and Baquero, M. and Diez-Fairen, M. and Lage, C. and García-Madrona, S. and García-González, P. and Alarcón-Martín, E. and Valero, S. and Sotolongo-Grau, O. and Ullgren, A. and Naj, A.C. and Lemstra, A.W. and Benaque, A. and Pérez-Cordón, A. and Benussi, A. and Rábano, A. and Padovani, A. and Squassina, A. and de Mendonça, A. and Arias Pastor, A. and Kok, A.A.L. and Meggy, A. and Pastor, A.B. and Espinosa, A. and Corma-Gómez, A. and Martín Montes, A. and Sanabria, Á. and DeStefano, A.L. and Schneider, A. and Haapasalo, A. and Kinhult Ståhlbom, A. and Tybjærg-Hansen, A. and Hartmann, A.M. and Spottke, A. and Corbatón-Anchuelo, A. and Rongve, A. and Borroni, B. and Arosio, B. and Nacmias, B. and Nordestgaard, B.G. and Kunkle, B.W. and Charbonnier, C. and Abdelnour, C. and Masullo, C. and Martínez Rodríguez, C. and Muñoz-Fernandez, C. and Dufouil, C. and Graff, C. and Ferreira, C.B. and Chillotti, C. and Reynolds, C.A. and Fenoglio, C. and Van Broeckhoven, C. and Clark, C. and Pisanu, C. and Satizabal, C.L. and Holmes, C. and Buiza-Rueda, D. and Aarsland, D. and Rujescu, D. and Alcolea, D. and Galimberti, D. and Wallon, D. and Seripa, D. and Grünblatt, E. and Dardiotis, E. and Düzel, E. and Scarpini, E. and Conti, E. and Rubino, E. and Gelpi, E. and Rodriguez-Rodriguez, E. and Duron, E. and Boerwinkle, E. and Ferri, E. and Tagliavini, F. and Küçükali, F. and Pasquier, F. and Sanchez-Garcia, F. and Mangialasche, F. and Jessen, F. and Nicolas, G. and Selbæk, G. and Ortega, G. and Chêne, G. and Hadjigeorgiou, G. and Rossi, G. and Spalletta, G. and Giaccone, G. and Grande, G. and Binetti, G. and Papenberg, G. and Hampel, H. and Bailly, H. and Zetterberg, H. and Soininen, H. and Karlsson, I.K. and Alvarez, I. and Appollonio, I. and Giegling, I. and Skoog, I. and Saltvedt, I. and Rainero, I. and Rosas Allende, I. and Hort, J. and Diehl-Schmid, J. and Van Dongen, J. and Vidal, J.S. and Lehtisalo, J. and Wiltfang, J. and Thomassen, J.Q. and Kornhuber, J. and Haines, J.L. and Vogelgsang, J. and Pineda, J.A. and Fortea, J. and Popp, J. and Deckert, J. and Buerger, K. and Morgan, K. and Fließbach, K. and Sleegers, K. and Molina-Porcel, L. and Kilander, L. and Weinhold, L. and Farrer, L.A. and Wang, L.S. and Kleineidam, L. and Farotti, L. and Parnetti, L. and Tremolizzo, L. and Hausner, L. and Benussi, L. and Froelich, L. and Ikram, M.A. and Deniz-Naranjo, M.C. and Tsolaki, M. and Rosende-Roca, M. and Löwenmark, M. and Hulsman, M. and Spallazzi, M. and Pericak-Vance, M.A. and Esiri, M. and Bernal Sánchez-Arjona, M. and Dalmasso, M.C. and Martínez-Larrad, M.T. and Arcaro, M. and Nöthen, M.M. and Fernández-Fuertes, M. and Dichgans, M. and Ingelsson, M. and Herrmann, M.J. and Scherer, M. and Vyhnalek, M. and Kosmidis, M.H. and Yannakoulia, M. and Schmid, M. and Ewers, M. and Heneka, M.T. and Wagner, M. and Scamosci, M. and Kivipelto, M. and Hiltunen, M. and Zulaica, M. and Alegret, M. and Fornage, M. and Roberto, N. and van Schoor, N.M. and Seidu, N.M. and Banaj, N. and Armstrong, N.J. and Scarmeas, N. and Scherbaum, N. and Goldhardt, O. and Hanon, O. and Peters, O. and Skrobot, O.A. and Quenez, O. and Lerch, O. and Bossù, P. and Caffarra, P. and Dionigi Rossi, P. and Sakka, P. and Mecocci, P. and Hoffmann, P. and Holmans, P.A. and Fischer, P. and Riederer, P. and Yang, Q. and Marshall, R. and Kalaria, R.N. and Mayeux, R. and Vandenberghe, R. and Cecchetti, R. and Ghidoni, R. and Frikke-Schmidt, R. and Sorbi, S. and Hägg, S. and Engelborghs, S. and Helisalmi, S. and Botne Sando, S. and Kern, S. and Archetti, S. and Boschi, S. and Fostinelli, S. and Gil, S. and Mendoza, S. and Mead, S. and Ciccone, S. and Djurovic, S. and Heilmann-Heimbach, S. and Riedel-Heller, S. and Kuulasmaa, T. and Del Ser, T. and Lebouvier, T. and Polak, T. and Ngandu, T. and Grimmer, T. and Bessi, V. and Escott-Price, V. and Giedraitis, V. and Deramecourt, Vi. and Maier, W. and Jian, X. and Pijnenburg, Y.A.L. and Kehoe, P.G. and Garcia-Ribas, G. and Sánchez-Juan, P. and Pastor, P. and Pérez-Tur, J. and Piñol-Ripoll, G. and Lopez de Munain, A. and García-Alberca, J.M. and Bullido, M.J. and Álvarez, V. and Lleó, A. and Real, L.M. and Mir, P. and Medina, M. and Scheltens, P. and Holstege, H. and Marquié, M. and Sáez, M.E. and Carracedo, Á. and Amouyel, P. and Schellenberg, G.D. and Williams, J. and Seshadri, S. and van Duijn, C.M. and Mather, K.A. and Sánchez-Valle, R. and Serrano-Ríos, M. and Orellana, A. and Tárraga, L. and Blennow, K. and Huisman, M. and Andreassen, O.A. and Posthuma, D. and Clarimón, J. and Boada, M. and van der Flier, W.M. and Ramirez, A. and Lambert, J.C. and van der Lee, S.J. and Ruiz, A.
Nature Communications 12 (1): 3417. 7 June 2021

2020

Value of neuropsychological tests to identify patients with depressive symptoms on the Alzheimer's disease continuum.
Menne, F. and Schipke, C.G. and Klostermann, A. and Fuentes-Casañ, M. and Freiesleben, S.D. and Bauer, C. and Peters, O.
Journal of Alzheimer's Disease 78 (2): 819-826. 10 November 2020

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P. and Newman, A.G. and Singh, M. and Hinz, M. and Szczepek, M. and Krüger, C. and Adalbert, R. and Dzaye, O. and Trimbuch, T. and Wallach, T. and Kleinau, G. and Derkow, K. and Richard, B.C. and Schipke, C. and Scheidereit, C. and Stachelscheid, H. and Golenbock, D. and Peters, O. and Coleman, M. and Heppner, F.L. and Scheerer, P. and Tarabykin, V. and Ruprecht, K. and Izsvák, Z. and Mayer, J. and Lehnardt, S.
JCI Insight 5 (7): e131093. 9 April 2020

2019

A combined miRNA-piRNA signature to detect Alzheimer's disease.
Jain, G. and Stuendl, A. and Rao, P. and Berulava, T. and Pena Centeno, T. and Kaurani, L. and Burkhardt, S. and Delalle, I. and Kornhuber, J. and Hüll, M. and Maier, W. and Peters, O. and Esselmann, H. and Schulte, C. and Deuschle, C. and Synofzik, M. and Wiltfang, J. and Mollenhauer, B. and Maetzler, W. and Schneider, A. and Fischer, A.
Translational Psychiatry 9 (1): 250. 7 October 2019

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P. and Newman, A.G. and Singh, M. and Hinz, M. and Szczepek, M. and Krüger, C. and Adalbert, R. and al-Dzaye, O. and Trimbuch, T. and Wallach, T. and Kleinau, G. and Derkow, K. and Richard, B.C. and Schipke, C. and Scheidereit, C. and Golenbock, D. and Peters, O. and Coleman, M. and Heppner, F.L. and Scheerer, P. and Tarabykin, V. and Ruprecht, K. and Izsvák, Z. and Mayer, J. and Lehnardt, S.
bioRxiv : 721241. 1 August 2019

2018

User experience and clinical effectiveness with two wearable global positioning system devices in home dementia care.
Megges, H. and Freiesleben, S.D. and Rösch, C. and Knoll, N. and Wessel, L. and Peters, O.
Alzheimer's and Dementia: Translational Research and Clinical Interventions 4 : 636-644. 9 November 2018

Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease.
Kork, F. and Jankowski, J. and Goswami, A. and Weis, J. and Brook, G. and Yamoah, A. and Anink, J. and Aronica, E. and Fritz, S. and Huck, C. and Schipke, C. and Peters, O. and Tepel, M. and Noels, H. and Jankowski, V.
Neurology 91 (19): e1799-e1808. 6 November 2018

2017

Correlation of florbetaben PET imaging and the amyloid peptide Aβ42 in cerebrospinal fluid.
Schipke, C.G. and Koglin, N. and Bullich, S. and Joachim, L.K. and Haas, B. and Seibyl, J. and Barthel, H. and Sabri, O. and Peters, O.
Psychiatry Research 265 : 98-101. 30 July 2017

2015

Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naive patients with mild-to-moderate Alzheimer's disease.
Peters, O. and Fuentes, M. and Joachim, L.K. and Jessen, F. and Luckhaus, C. and Kornhuber, J. and Pantel, J. and Huell, M. and Schmidtke, K. and Ruether, E. and Moeller, H.J. and Kurz, A. and Wiltfang, J. and Maier, W. and Wiese, B. and Froelich, L. and Heuser, I.
Alzheimer's and Dementia 1 (3): 198-204. November 2015

Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood.
Memczak, S. and Papavasileiou, P. and Peters, O. and Rajewsky, N.
PLoS ONE 10 (10): e0141214. 20 October 2015

The latent dementia phenotype δ is associated with cerebrospinal fluid biomarkers of Alzheimer's disease and predicts conversion to dementia in subjects with mild cognitive impairment.
Koppara, A. and Wolfsgruber, S. and Kleineidam, L. and Schmidtke, K. and Froelich, L. and Kurz, A. and Schulz, S. and Hampel, H. and Heuser, I. and Peters, O. and Reischies, F.M. and Jahn, H. and Luckhaus, C. and Huell, M. and Gertz, H.J. and Schroeder, J. and Pantel, J. and Rienhoff, O. and Ruether, E. and Henn, F. and Wiltfang, J. and Maier, W. and Jessen, F. and Kornhuber, J. and Wagner, M.
Journal of Alzheimer's Disease 49 (2): 547-560. 17 October 2015

Validation of the Erlangen score algorithm for the prediction of the development of dementia due to Alzheimer's disease in pre-dementia subjects.
Lewczuk, P. and Kornhuber, J. and Toledo, J.B. and Trojanowski, J.Q. and Knapik-Czajka, M. and Peters, O. and Wiltfang, J. and Shaw, L.M.
Journal of Alzheimer's Disease 48 (2): 433-441. 9 September 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.
Jansen, W.J. and Ossenkoppele, R. and Knol, D.L. and Tijms, B.M. and Scheltens, P. and Verhey, F.R.J. and Visser, P.J.
JAMA: Journal of the American Medical Association 313 (19): 1924-1938. 19 May 2015

Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study.
Morgen, K. and Schneider, M. and Frölich, L. and Tost, H. and Plichta, M.M. and Kölsch, H. and Rakebrandt, F. and Rienhoff, O. and Jessen, F. and Peters, O. and Jahn, H. and Luckhaus, C. and Hüll, M. and Gertz, H.J. and Schröder, J. and Hampel, H. and Teipel, S.J. and Pantel, J. and Heuser, I. and Wiltfang, J. and Rüther, E. and Kornhuber, J. and Maier, W. and Meyer-Lindenberg, A.
Alzheimer's Research & Therapy 7 (1): 27. 15 May 2015

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage.
Vos, S.J.B. and Verhey, F. and Froelich, L. and Kornhuber, J. and Wiltfang, J. and Maier, W. and Peters, O. and Ruether, E. and Nobili, F. and Morbelli, S. and Frisoni, G.B. and Drzezga, A. and Didic, M. and van Berckel, B.N.M. and Simmons, A. and Soininen, H. and Kloszewska, I. and Mecocci, P. and Tsolaki, M. and Vellas, B. and Lovestone, S. and Muscio, C. and Herukka, S.K. and Salmon, E. and Bastin, C. and Wallin, A. and Nordlund, A. and de Mendonca, A. and Silva, D. and Santana, I. and Lemos, R. and Engelborghs, S. and Van der Mussele, S. and Freund-Levi, Y. and Wallin, A.K. and Hampel, H. and van der Flier, W. and Scheltens, P. and Visser, P.J.
Brain 138 (Pt 5): 1327-1338. May 2015

PLD3 in non-familial Alzheimer's disease.
Heilmann, S. and Drichel, D. and Clarimon, J. and Fernández, V. and Lacour, A. and Wagner, H. and Thelen, M. and Hernández, I. and Fortea, J. and Alegret, M. and Blesa, R. and Mauleón, A. and Roca, M.R. and Kornhuber, J. and Peters, O. and Heun, R. and Frölich, L. and Hüll, M. and Heneka, M.T. and Rüther, E. and Riedel-Heller, S. and Scherer, M. and Wiltfang, J. and Jessen, F. and Becker, T. and Tárraga, L. and Boada, M. and Maier, W. and Lleó, A. and Ruiz, A. and Nöthen, M.M. and Ramirez, A.
Nature 520 (7545): E3-E5. 2 April 2015

Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI.
Wolfsgruber, S. and Jessen, F. and Koppara, A. and Kleineidam, L. and Schmidtke, K. and Froelich, L. and Kurz, A. and Schulz, S. and Hampel, H. and Heuser, I. and Peters, O. and Reischies, F.M. and Jahn, H. and Luckhaus, C. and Huell, M. and Gertz, H.J. and Schroeder, J. and Pantel, J. and Rienhoff, O. and Ruether, E. and Henn, F. and Wiltfang, J. and Maier, W. and Kornhuber, J. and Wagner, M.
Neurology 84 (12): 1261-1268. 24 March 2015

The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease.
Louwersheimer, E. and Ramirez, A. and Cruchaga, C. and Becker, T. and Kornhuber, J. and Peters, O. and Heilmann, S. and Wiltfang, J. and Jessen, F. and Visser, P.J. and Scheltens, P. and Pijnenburg, Y.A.L. and Teunissen, C.E. and Barkhof, F. and van Swieten, J.C. and Holstege, H. and van der Flier, W.M.
Neurobiology of Aging 36 (3): 1605.e13-1605.e20. March 2015

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type.
Popp, J. and Wolfsgruber, S. and Heuser, I. and Peters, O. and Huell, M. and Schroeder, J. and Moeller, H.J. and Lewczuk, P. and Schneider, A. and Jahn, H. and Luckhaus, C. and Perneczky, R. and Froelich, L. and Wagner, M. and Maier, W. and Wiltfang, J. and Kornhuber, J. and Jessen, F.
Neurobiology of Aging 36 (2): 601-607. February 2015

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey.
Bocchetta, M. and Galluzzi, S. and Kehoe, P.G. and Aguera, E. and Bernabei, R. and Bullock, R. and Ceccaldi, M. and Dartigues, J.F. and de Mendonca, A. and Didic, M. and Eriksdotter, M. and Felician, O. and Froelich, L. and Gertz, H.J. and Hallikainen, M. and Hasselbalch, S.G. and Hausner, L. and Heuser, I. and Jessen, F. and Jones, R.W. and Kurz, A. and Lawlor, B. and Lleo, A. and Martinez-Lage, P. and Mecocci, P. and Mehrabian, S. and Monsch, A. and Nobili, F. and Nordberg, A. and Rikkert, M.O. and Orgogozo, J.M. and Pasquier, F. and Peters, O. and Salmon, E. and Sanchez-Castellano, C. and Santana, I. and Sarazin, M. and Traykov, L. and Tsolaki, M. and Visser, P.J. and Wallin, A.K. and Wilcock, G. and Wilkinson, D. and Wolf, H. and Yener, G. and Zekry, D. and Frisoni, G.B.
Alzheimer's & Dementia 11 (2): 195-206. February 2015

Alzheimer amyloid Peptide aβ42 regulates gene expression of transcription and growth factors.
Barucker, C. and Sommer, A. and Beckmann, G. and Eravci, M. and Harmeier, A. and Schipke, C.G. and Brockschnieder, D. and Dyrks, T. and Althoff, V. and Fraser, P.E. and Hazrati, L.N. and St George-Hyslop, P. and Breitner, J.C.S. and Peters, O. and Multhaup, G.
Journal of Alzheimer's Disease 44 (2): 613-624. 1 January 2015

2014

SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
Ramirez, A. and van der Flier, W.M. and Herold, C. and Ramonet, D. and Heilmann, S. and Lewczuk, P. and Popp, J. and Lacour, A. and Drichel, D. and Louwersheimer, E. and Kummer, M.P. and Cruchaga, C. and Hoffmann, P. and Teunissen, C. and Holstege, H. and Kornhuber, J. and Peters, O. and Naj, A.C. and Chouraki, V. and Bellenguez, C. and Gerrish, A. and Heun, R. and Froelich, L. and Huell, M. and Buscemi, L. and Herms, S. and Koelsch, H. and Scheltens, P. and Breteler, M.M. and Ruether, E. and Wiltfang, J. and Goate, A. and Jessen, F. and Maier, W. and Heneka, M.T. and Becker, T. and Noethen, M.M.
Human Molecular Genetics 23 (24): 6644-6658. 15 December 2014

Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes.
Thelen, M. and Razquin, C. and Hernandez, I. and Gorostidi, A. and Sanchez-Valle, R. and Ortega-Cubero, S. and Wolfsgruber, S. and Drichel, D. and Fliessbach, K. and Duenkel, T. and Damian, M. and Heilmann, S. and Slotosch, A. and Lennarz, M. and Seijo-Martinez, M. and Rene, R. and Kornhuber, J. and Peters, O. and Luckhaus, C. and Jahn, H. and Huell, M. and Ruether, E. and Wiltfang, J. and Lorenzo, E. and Gascon, J. and Lleo, A. and Llado, A. and Campdelacreu, J. and Moreno, F. and Ahmadzadehfar, H. and Fortea, J. and Indakoetxea, B. and Heneka, M.T. and Wetter, A. and Pastor, M.A. and Riverol, M. and Becker, T. and Froelich, L. and Tarraga, L. and Boada, M. and Wagner, M. and Jessen, F. and Maier, W. and Clarimon, J. and Lopez de Munain, A. and Ruiz, A. and Pastor, P. and Ramirez, A.
Neurobiology of Aging 35 (11): 2657.e13-2657.e19. November 2014

The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.
Hooli, B.V. and Parrado, A.R. and Mullin, K. and Yip, W.K. and Liu, T. and Roehr, J.T. and Qiao, D. and Jessen, F. and Peters, O. and Becker, T. and Ramirez, A. and Lange, C. and Bertram, L. and Tanzi, R.E.
Neurology 83 (15): 1353-1358. 7 October 2014

Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease.
Morgen, K. and Ramirez, A. and Froelich, L. and Tost, H. and Plichta, M.M. and Koelsch, H. and Rakebrandt, F. and Rienhoff, O. and Jessen, F. and Peters, O. and Jahn, H. and Luckhaus, C. and Huell, M. and Gertz, H.J. and Schroeder, J. and Hampel, H. and Teipel, S.J. and Pantel, J. and Heuser, I. and Wiltfang, J. and Ruether, E. and Kornhuber, J. and Maier, W. and Meyer-Lindenberg, A.
Alzheimer's & Dementia 10 (5 Suppl): S269-S276. October 2014

Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment.
Wolfsgruber, S. and Wagner, M. and Schmidtke, K. and Froelich, L. and Kurz, A. and Schulz, S. and Hampel, H. and Heuser, I. and Peters, O. and Reischies, F.M. and Jahn, H. and Luckhaus, C. and Huell, M. and Gertz, H.J. and Schroeder, J. and Pantel, J and Rienhoff, O. and Ruether, E. and Henn, F. and Wiltfang, J. and Maier, W. and Kornhuber, J. and Jessen, F.
PLoS ONE 9 (7): e100812. 14 July 2014

2013

Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism.
de Souza Silva, M.A. and Lenz, B. and Rotter, A. and Biermann, T. and Peters, O. and Ramirez, A. and Jessen, F. and Maier, W. and Huell, M. and Schroeder, J. and Froelich, L. and Teipel, S. and Gruber, O. and Kornhuber, J. and Huston, J.P. and Mueller, C.P. and Schaeble, S.
Proceedings of the National Academy of Sciences of the United States of America 110 (37): 15097-15102. 10 September 2013

APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease.
Morgen, K. and Froelich, L. and Tost, H. and Plichta, M.M. and Koelsch, H. and Rakebrandt, F. and Rienhoff, O. and Jessen, F. and Peters, O. and Jahn, H. and Luckhaus, C. and Huell, M. and Gertz, H.J. and Schroeder, J. and Hampel, H. and Teipel, S.J. and Pantel, J. and Heuser, I. and Wiltfang, J. and Ruether, E. and Kornhuber, J. and Maier, W. and Meyer-Lindenberg, A.
Journal of Alzheimer's Disease 37 (2): 389-401. 3 July 2013

Liquordiagnostik bei Demenzen [CSF biomarkers in dementia].
Peters, O. and Schipke, C.G.
Nervenheilkunde 32 (10): 733-736. 2013

2012

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline.
Vom Berg, J. and Prokop, S. and Miller, K.R. and Obst, J. and Kaelin, R.E. and Lopategui-Cabezas, I. and Wegner, A. and Mair, F. and Schipke, C.G. and Peters, O. and Winter, Y. and Becher, B. and Heppner, F.L.
Nature Medicine 18 (12): 1812-1819. December 2012

Morbus Alzheimer: Sind nicht-steroidale Antiphlogistika und Steroide wirksam? [Alzheimer's disease: are non-steroidal anti-inflammatory drugs effective?].
Peters, O.
Deutsche Medizinische Wochenschrift 137 (50): 2627. December 2012

A polymorphic microsatellite repeat within the ECE-1c promoter is involved in transcriptional start site determination, human evolution, and Alzheimer's disease.
Li, Y. and Seidel, K. and Marschall, P. and Klein, M. and Hope, A. and Schacherl, J. and Schmitz, J. and Menk, M. and Schefe, J.H. and Reinemund, J. and Hugel, R. and Walden, P. and Schlosser, A. and Volkmer, R. and Schimkus, J. and Koelsch, H. and Maier, W. and Kornhuber, J. and Froelich, L. and Klare, S. and Kirsch, S. and Schmerbach, K. and Scheele, S. and Grittner, U. and Zollmann, F. and Goldin-Lang, P. and Peters, O. and Kintscher, U. and Unger, T. and Funke-Kaiser, H.
Journal of Neuroscience 32 (47): 16807-16820. 21 November 2012

Impact of beta-amyloid-specific florbetaben PET imaging on confidence in early diagnosis of Alzheimer's disease.
Schipke, C.G. and Peters, O. and Heuser, I. and Grimmer, T. and Sabbagh, M.N. and Sabri, O. and Hock, C. and Kunz, M. and Kuhlmann, J. and Reininger, C. and Blankenburg, M.
Dementia and Geriatric Cognitive Disorders 33 (6): 416-422. August 2012

A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI.
Peters, O. and Lorenz, D. and Fesche, A. and Schmidtke, K. and Hull, M. and Perneczky, R. and Ruether, E. and Moeller, H.J. and Jessen, F. and Maier, W. and Kornhuber, J. and Jahn, H. and Luckhaus, C. and Gertz, H.J. and Schroeder, J. and Pantel, J. and Teipel, S. and Wellek, S. and Froelich, L. and Heuser, I.
Journal of Nutrition Health & Aging 16 (6): 544-548. June 2012

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann, S.M. and Krueger, C. and Park, B. and Derkow, K. and Rosenberger, K. and Baumgart, J. and Trimbuch, T. and Eom, G. and Hinz, M. and Kaul, D. and Habbel, P. and Kaelin, R. and Franzoni, E. and Rybak, A. and Nguyen, D. and Veh, R. and Ninnemann, O. and Peters, O. and Nitsch, R. and Heppner, F.L. and Golenbock, D. and Schott, E. and Ploegh, H.L. and Wulczyn, F.G. and Lehnardt, S.
Nature Neuroscience 15 (6): 827-835. June 2012

Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease.
Wagner, M. and Wolf, S. and Reischies, F.M. and Daerr, M. and Wolfsgruber, S. and Jessen, F. and Popp, J. and Maier, W. and Huell, M. and Froelich, L. and Hampel, H. and Perneczky, R. and Peters, O. and Jahn, H. and Luckhaus, C. and Gertz, H.J. and Schroeder, J. and Pantel, J. and Lewczuk, P. and Kornhuber, J. and Wiltfang, J.
Neurology 78 (6): 379-386. 7 February 2012

Genome-wide association study of vascular dementia.
Schrijvers, E.M. and Schuermann, B. and Koudstaal, P.J. and van den Bussche, H. and Van Duijn, C.M. and Hentschel, F. and Heun, R. and Hofman, A. and Jessen, F. and Koelsch, H. and Kornhuber, J. and Peters, O. and Rivadeneira, F. and Ruether, E. and Uitterlinden, A.G. and Riedel-Heller, S. and Dichgans, M. and Wiltfang, J. and Maier, W. and Breteler, M.M.B. and Ikram, M.A.
Stroke 43 (2): 315-319. February 2012

2011

Left anterior temporal lobe sustains naming in Alzheimer's dementia and mild cognitive impairment.
Frings, L. and Kloeppel, S. and Teipel, S. and Peters, O. and Froelich, L. and Pantel, J. and Schroeder, J. and Gertz, H.J. and Arlt, S. and Heuser, I. and Kornhuber, J. and Wiltfang, J. and Maier, W. and Jessen, F. and Hampel, H. and Huell, M.
Current Alzheimer Research 8 (8): 893-901. December 2011

Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: effect of different processing and analysis approaches on sample sizes.
Teipel, S.J. and Peters, O. and Heuser, I. and Jessen, F. and Maier, W. and Froelich, L. and Arlt, S. and Huell, M. and Gertz, H.J. and Kornhuber, J. and Wiltfang, J. and Thome, J. and Rienhoff, O. and Meindl, T. and Hampel, H. and Grothe, M.
World Journal of Biological Psychiatry 12 (Suppl 1): 109-113. September 2011

Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study.
Barthel, H. and Gertz, H.J. and Dresel, S. and Peters, O. and Bartenstein, P. and Buerger, K. and Hiemeyer, F. and Wittemer-Rump, S.M. and Seibyl, J. and Reininger, C. and Sabri, O.
Lancet Neurology 10 (5): 424-435. May 2011

Comparison of immunosorbent assays for the quantification of biomarkers for Alzheimer's disease in human cerebrospinal fluid.
Schipke, C.G. and Prokop, S. and Heppner, F.L. and Heuser, I. and Peters, O.
Dementia and Geriatric Cognitive Disorders 31 (2): 139-145. March 2011

Antidepressants act on glial cells: SSRIs and serotonin elicit astrocyte calcium signaling in the mouse prefrontal cortex.
Schipke, C.G. and Heuser, I. and Peters, O.
Journal of Psychiatric Research 45 (2): 242-248. February 2011

Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia.
Jessen, F. and Lewczuk, P. and Guer, O. and Block, W. and Ende, G. and Froelich, L. and Hammen, T. and Arlt, S. and Kornhuber, J. and Kucinski, T. and Popp, J. and Peters, O. and Maier, W. and Traeber, F. and Wiltfang, J.
Journal of Alzheimer's Disease 27 (2): 393-399. 2011

Long-term stability of Alzheimer's disease biomarker proteins in cerebrospinal fluid.
Schipke, C.G. and Jessen, F. and Teipel, S. and Luckhaus, C. and Wiltfang, J. and Esselmann, H. and Froelich, L. and Maier, W. and Ruether, E. and Heppner, F.L. and Prokop, S. and Heuser, I. and Peters, O.
Journal of Alzheimer's Disease 26 (2): 255-262. 2011

2010

A novel MRI-biomarker candidate for Alzheimer's disease composed of regional brain volume and perfusion variables.
Luckhaus, C. and Jaenner, M. and Cohnen, M. and Fluess, M.O. and Teipel, S.J. and Grothe, M. and Hampel, H. and Kornhuber, J. and Ruether, E. and Peters, O. and Supprian, T. and Gaebel, W. and Moedder, U. and Wittsack, H.J.
European Journal of Neurology 17 (12): 1437-1444. December 2010

The relation of regional cerebral perfusion and atrophy in mild cognitive impairment (MCI) and early Alzheimer's dementia.
Luckhaus, C. and Cohnen, M. and Fluess, M.O. and Jaenner, M. and Grass-Kapanke, B. and Teipel, S.J. and Grothe, M. and Hampel, H. and Peters, O. and Kornhuber, J. and Maier, W. and Supprian, T. and Gaebel, W. and Moedder, U. and Wittsack, H.J.
Psychiatry Research 183 (1): 44-51. 30 July 2010

Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease.
Teipel, S.J. and Ewers, M. and Wolf, S. and Jessen, F. and Koelsch, H. and Arlt, S. and Luckhaus, C. and Schoenknecht, P. and Schmidtke, K. and Heuser, I. and Froelich, L. and Ende, G. and Pantel, J. and Wiltfang, J. and Rakebrandt, F. and Peters, O. and Born, C. and Kornhuber, J. and Hampel, H.
Psychiatry Research 182 (3): 244-250. 30 June 2010

Amyloid beta peptides in plasma in early diagnosis of Alzheimer's disease: a multicenter study with multiplexing.
Lewczuk, P. and Kornhuber, J. and Vanmechelen, E. and Peters, O. and Heuser, I. and Maier, W. and Jessen, F. and Buerger, K. and Hampel, H. and Froelich, L. and Henn, F. and Falkai, P. and Ruether, E. and Jahn, H. and Luckhaus, C. and Perneczky, R. and Schmidtke, K. and Schroeder, J. and Kessler, H. and Pantel, J. and Gertz, H.J. and Vanderstichele, H. and de Meyer, G. and Shapiro, F. and Wolf, S. and Bibl, M. and Wiltfang, J.
Experimental Neurology 223 (2): 366-370. June 2010

Neuropsychologische Therapie. Grundlagen und Praxis der Behandlung kognitiver Stoerungen bei neurologischen Erkrankungen [Neuropsychological therapy. Fundamentals and practice of the treatments on cognitive disorders in neurological disease].
Beinhoff, U. and Buhrsch, N. and Peters, O.
Neuroforum 16 (2): 205-206. June 2010

Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study.
Lewczuk, P. and Kamrowski-Kruck, H. and Peters, O. and Heuser, I. and Jessen, F. and Popp, J. and Buerger, K. and Hampel, H. and Froelich, L. and Wolf, S. and Prinz, B. and Jahn, H. and Luckhaus, C. and Perneczky, R. and Huell, M. and Schroeder, J. and Kessler, H. and Pantel, J. and Gertz, H.J. and Klafki, H.W. and Koelsch, H. and Reulbach, U. and Esselmann, H. and Maler, J.M. and Bibl, M. and Kornhuber, J. and Wiltfang, J.
Molecular Psychiatry 15 (2): 138-145. February 2010

2009

A possible new diagnostic biomarker in early diagnosis of Alzheimer's disease.
Kork, F. and Holthues, J. and Hellweg, R. and Jankowski, V. and Tepel, M. and Ohring, R. and Heuser, I. and Bierbrauer, J. and Peters, O. and Schlattmann, P. and Zidek, W. and Jankowski, J.
Current Alzheimer Research 6 (6): 519-524. December 2009

Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network.
Kornhuber, J. and Schmidtke, K. and Froelich, L. and Perneczky, R. and Wolf, S. and Hampel, H. and Jessen, F. and Heuser, I. and Peters, O. and Weih, M. and Jahn, H. and Luckhaus, C. and Huell, M. and Gertz, H.J. and Schroeder, J. and Pantel, J. and Rienhoff, O. and Seuchter, S.A. and Ruether, E. and Henn, F. and Maier, W. and Wiltfang, J.
Dementia and Geriatric Cognitive Disorders 27 (5): 404-417. June 2009

Association of SORL1 gene variants with Alzheimer's disease.
Koelsch, H. and Jessen, F. and Wiltfang, J. and Lewczuk, P. and Dichgans, M. and Teipel, S.J. and Kornhuber, J. and Froelich, L. and Heuser, I. and Peters, O. and Wiese, B. and Kaduszkiewicz, H. and van den Bussche, H. and Huell, M. and Kurz, A. and Ruether, E. and Henn, F.A. and Maier, W.
Brain Research 1264 : 1-6. 6 April 2009

Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia.
Alexopoulos, P. and Guenther, F. and Popp, J. and Jessen, F. and Peters, O. and Wolf, S. and Kneib, T. and Kurz, A. and Richter-Schmidinger, T. and Lewczuk, P. and Bleich, S. and Wiltfang, J. and Kornhuber, J.
Journal of the American Geriatrics Society 57 (4): 737-739. April 2009

Astrocyte function is modified by Alzheimer's disease-like pathology in aged mice.
Peters, O. and Schipke, C.G. and Philipps, A. and Haas, B. and Pannasch, U. and Wang, L.P. and Benedetti, B. and Kingston, A.E. and Kettenmann, H.
Journal of Alzheimer's Disease 18 (1): 177-189. 2009

Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form.
Klafki, H.W. and Lewczuk, P. and Kamrowski-Kruck, H. and Maler, J.M. and Mueller, K. and Peters, O. and Heuser, I. and Jessen, F. and Popp, J. and Froelich, L. and Wolf, S. and Prinz, B. and Luckhaus, C. and Schroeder, J. and Pantel, J. and Gertz, H.J. and Koelsch, H. and Mueller, B.W. and Esselmann, H. and Bibl, M. and Kornhuber, J. and Wiltfang, J.
Journal of Alzheimer's Disease 18 (3): 613-622. 2009

2008

Influence of SORL1 gene variants: association with CSF amyloid-β products in probable Alzheimer's disease.
Koelsch, H. and Jessen, F. and Wiltfang, J. and Lewczuk, P. and Dichgans, M. and Kornhuber, J. and Froelich, L. and Heuser, I. and Peters, O. and Schulz, J.B. and Schwab, S.G. and Maier, W.
Neuroscience Letters 440 (1): 68-71. 25 July 2008

Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study.
Lewczuk, P. and Kornhuber, J. and Vanderstichele, H. and Vanmechelen, E. and Esselmann, H. and Bibl, M. and Wolf, S. and Otto, M. and Reulbach, U. and Koelsch, H. and Jessen, F. and Schroeder, J. and Schoenknecht, P. and Hampel, H. and Peters, O. and Weimer, E. and Perneczky, R. and Jahn, H. and Luckhaus, C. and Lamla, U. and Supprian, T. and Maler, J.M. and Wiltfang, J.
Neurobiology of Aging 29 (6): 812-818. June 2008

Temperature and nitric oxide control spontaneous calcium transients in astrocytes.
Schipke, C.G. and Heidemann, A. and Skupin, A. and Peters, O. and Falcke, M. and Kettenmann, H.
Cell Calcium 43 (3): 285-295. March 2008

2007

Amyloidβ peptide ratio 42/40 but not Aβ42 correlates with phospho-Tau in patients with low- and high-CSF Aβ40 load.
Wiltfang, J. and Esselmann, H. and Bibl, M. and Huell, M. and Hampel, H. and Kessler, H. and Froelich, L. and Schroeder, J. and Peters, O. and Jessen, F. and Luckhaus, C. and Perneczky, R. and Jahn, H. and Fiszer, M. and Maler, J.M. and Zimmermann, R. and Bruckmoser, R. and Kornhuber, J. and Lewczuk, P.
Journal of Neurochemistry 101 (4): 1053-1059. May 2007

2006

Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves.
Haas, B. and Schipke, C.G. and Peters, O. and Soehl, G. and Willecke, K. and Kettenmann, H.
Cerebral Cortex 16 (2): 237-246. February 2006

2005

Increased extracellular K+ concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression-like depolarizations and spreading ischemia.
Petzold, G.C. and Windmueller, O. and Haack, S. and Major, S. and Buchheim, K. and Megow, D. and Gabriel, S. and Lehmann, T.N. and Drenckhahn, C. and Peters, O. and Meierkord, H. and Heinemann, U. and Dirnagl, U. and Dreier, J.P.
Stroke 36 (6): 1270-1277. June 2005

Zinc ions are endogenous modulators of neurotransmitter-stimulated capacitative Ca2+ entry in both cultured and in situ mouse astrocytes.
Kresse, W. and Sekler, I. and Hoffmann, A. and Peters, O. and Nolte, C. and Moran, A. and Kettenmann, H.
European Journal of Neuroscience 21 (6): 1626-1634. 1 January 2005

Combination therapy in dementia [Antidementive kombinationstherapie].
Peters, O. and Froelich, L. and Heuser, I.
Nervenheilkunde 24 (6): 476-482. 2005

2004

Impaired synaptic plasticity in the surround of perinatally acquired dysplasia in rat cerebral cortex.
Peters, O. and Redecker, C. and Hagemann, G. and Bruehl, C. and Luhmann, H.J. and Witte, O.W.
Cerebral Cortex 14 (10): 1081-1087. October 2004

2003

Different mechanisms promote astrocyte Ca2+ waves and spreading depression in the mouse neocortex.
Peters, O. and Schipke, C.G. and Hashimoto, Y. and Kettenmann, H.
Journal of Neuroscience 23 (30): 9888-9896. 29 October 2003

2001

Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain.
Jander, S. and Schroeter, M. and Peters, O. and Witte, O.W. and Stoll, G.
Journal of Cerebral Blood Flow and Metabolism 21 (3): 218-225. March 2001

1998

Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat.
Peters, O. and Back, T. and Lindauer, U. and Busch, C. and Megow, D. and Dreier, J. and Dirnagl, U.
Journal of Cerebral Blood Flow and Metabolism 18 (2): 196-205. February 1998