Article
Kommentar zu den Leitlinien 2023 der ESC zum Management von Kardiomyopathien.
Meder, B., Eckardt, L., Falk, V., Klaassen, S., Klingenheben, T., Knebel, F., Schulze-Bahr, E. and Schulz-Menger, J.
Kardiologie
9 April 2024
Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch, J., Theisen, S., Dartsch, J., Fritsche-Guenther, R., Kirchner, M., Obermayer, B., Bauer, A., Kahlert, A.K., Rothe, M., Beule, D., Heuser, A., Mertins, P., Kirwan, J.A., Berndt, N., MacRae, C.A., Hubner, N. and Klaassen, S.
Cardiovascular Research 119
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December 2023
Linee guida ESC 2023 per il trattamento delle cardiomiopatie [2023 ESC Guidelines for the management of cardiomyopathies].
Arbelo, E., Protonotarios, A., Gimeno, J.R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C.R., Biagini, E., Blom, N.A., de Boer, R.A., De Winter, T., Elliott, P.M., Flather, M., Garcia-Pavia, P., Haugaa, K.H., Ingles, J., Jurcut, R.O., Klaassen, S., Limongelli, G., Loeys, B., Mogensen, J., Olivotto, I., Pantazis, A., Sharma, S., Van Tintelen, J.P., Ware, J.S. and Kaski, J.P.
Giornale Italiano di Cardiologia 24
(11): 1e-127e.
November 2023
2023 ESC Guidelines for the management of cardiomyopathies: developed by the task force on the management of cardiomyopathies of the European Society of Cardiology (ESC).
Arbelo, E., Protonotarios, A., Gimeno, J.R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C.R., Biagini, E., Blom, N.A., de Boer, R.A., De Winter, T., Elliott, P.M., Flather, M., Garcia-Pavia, P., Haugaa, K.H., Ingles, J., Jurcut, R.O., Klaassen, S., Limongelli, G., Loeys, B., Mogensen, J., Olivotto, I., Pantazis, A., Sharma, S., Van Tintelen, J.P., Ware, J.S. and Kaski, J.P.
European Heart Journal 44
(37): 3503-3626.
1 October 2023
Myocarditis and sports in the young: data from a nationwide registry on myocarditis - "MYKKE-Sport".
Schöffl, I., Holler, S., Dittrich, S., Pickardt, T., Opgen-Rhein, B., Boehne, M., Wannenmacher, B., Reineke, K., Wiegand, G., Hecht, T., Kaestner, M., Messroghli, D., Schubert, S., Seidel, F. and Weigelt, A.
Frontiers in Sports and Active Living 5
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26 June 2023
Indications and management of implantable cardioverter-defibrillator therapy in childhood hypertrophic cardiomyopathy.
Kaski, J.P., Kammeraad, J.A.E., Blom, N.A., Happonen, J.M., Janousek, J., Klaassen, S., Limongelli, G., Östman-Smith, I., Sarquella Brugada, G. and Ziolkowska, L.
Cardiology in the Young 33
(5): 681-698.
May 2023
Cardiovascular magnetic resonance in children with suspected myocarditis: current practice and applicability of adult protocols.
Pitak, B., Opgen-Rhein, B., Schubert, S., Reineker, K., Wiegand, G., Boecker, D., Rentzsch, A., Ruf, B., Özcan, S., Wannenmacher, B., Pickardt, T., Seidel, F. and Messroghli, D.
Cardiology in the Young 32
(12): 1957-1965.
December 2022
Acute myocarditis associated with desmosomal gene variants.
Ammirati, E., Raimondi, F., Piriou, N., Sardo Infirri, L., Mohiddin, S.A., Mazzanti, A., Shenoy, C., Cavallari, U.A., Imazio, M., Aquaro, G.D., Olivotto, I., Pedrotti, P., Sekhri, N., Van de Heyning, C.M., Broeckx, G., Peretto, G., Guttmann, O., Dellegrottaglie, S., Scatteia, A., Gentile, P., Merlo, M., Goldberg, R.I., Reyentovich, A., Sciamanna, C., Klaassen, S., Poller, W., Trankle, C.R., Abbate, A., Keren, A., Horowitz-Cederboim, S., Cadrin-Tourigny, J., Tadros, R., Annoni, G.A., Bonoldi, E., Toquet, C., Marteau, L., Probst, V., Trochu, J.N., Kissopoulou, A., Grosu, A., Kukavica, D., Trancuccio, A., Gil, C., Tini, G., Pedrazzini, M., Torchio, M., Sinagra, G., Gimeno, J.R., Bernasconi, D., Valsecchi, M.G., Klingel, K., Adler, E.D., Camici, P.G. and Cooper, L.T.
JACC Heart Fail 10
(10): 714-727.
October 2022
Kardiomyopathie im Neugeborenenalter: Forschungsfortschritte eröffnen neue diagnostische Möglichkeiten [Cardiomyopathy in neonatal age: advances in research open up new diagnostic possibilities].
Frenzel, M., Klaassen, S., Klingel, K., Knirsch, W., Kretschmar, O., Kühnisch, J. and Oxenius, A.
Monatsschrift Kinderheilkunde 170
: 912–916.
October 2022
Pathogenic variants in cardiomyopathy disorder genes underlie pediatric myocarditis - Further impact of heterozygous immune disorder gene variants?
Seidel, F., Laser, K.T., Klingel, K., Dartsch, J., Theisen, S., Pickardt, T., Holtgrewe, M., Gärtner, A., Berger, F., Beule, D., Milting, H., Schubert, S., Klaassen, S. and Kühnisch, J.
Journal of Cardiovascular Development and Disease 9
(7): 216.
5 July 2022
Clinical characteristics and outcome of biopsy-proven myocarditis in children - Results of the German prospective multicentre registry "MYKKE".
Seidel, F., Opgen-Rhein, B., Rentzsch, A., Boehne, M., Wannenmacher, B., Boecker, D., Reineker, K., Grafmann, M., Wiegand, G., Hecht, T., Kiski, D., Fischer, M., Papakostas, K., Ruf, B., Kramp, J., Khalil, M., Kaestner, M., Steinmetz, M., Fischer, G., Özcan, S., Freudenthal, N., Schweigmann, U., Hellwig, R., Pickardt, T., Klingel, K., Messroghli, D. and Schubert, S.
International Journal of Cardiology 357
: 95-104.
15 June 2022
Disease relevance of rare VPS13B missense variants for neurodevelopmental Cohen syndrome.
Zorn, M., Kühnisch, J., Bachmann, S. and Seifert, W.
Scientific Reports 12
(1): 9686.
11 June 2022
Clinical features and natural history of preadolescent nonsyndromic hypertrophic cardiomyopathy.
Norrish, G., Cleary, A., Field, E., Cervi, E., Boleti, O., Ziółkowska, L., Olivotto, I., Khraiche, D., Limongelli, G., Anastasakis, A., Weintraub, R., Biagini, E., Ragni, L., Prendiville, T., Duignan, S., McLeod, K., Ilina, M., Fernandez, A., Marrone, C., Bökenkamp, R., Baban, A., Kubus, P., Daubeney, P.E.F., Sarquella-Brugada, G., Cesar, S., Klaassen, S., Ojala, T.H., Bhole, V., Medrano, C., Uzun, O., Brown, E., Gran, F., Sinagra, G., Castro, F.J., Stuart, G., Yamazawa, H., Barriales-Villa, R., Garcia-Guereta, L., Adwani, S., Linter, K., Bharucha, T., Gonzales-Lopez, E., Siles, A., Rasmussen, T.B., Calcagnino, M., Jones, C.B., De Wilde, H., Kubo, T., Felice, T., Popoiu, A., Mogensen, J., Mathur, S., Centeno, F., Reinhardt, Z., Schouvey, S., Elliott, P.M. and Kaski, J.P.
Journal of the American College of Cardiology 79
(20): 1986-1997.
24 May 2022
Relationship between maximal left ventricular wall thickness and sudden cardiac death in childhood onset hypertrophic cardiomyopathy.
Norrish, G., Ding, T., Field, E., Cervi, E., Ziółkowska, L., Olivotto, I., Khraiche, D., Limongelli, G., Anastasakis, A., Weintraub, R., Biagini, E., Ragni, L., Prendiville, T., Duignan, S., McLeod, K., Ilina, M., Fernandez, A., Marrone, C., Bökenkamp, R., Baban, A., Kubus, P., Daubeney, P.E.F., Sarquella-Brugada, G., Cesar, S., Klaassen, S., Ojala, T.H., Bhole, V., Medrano, C., Uzun, O., Brown, E., Gran, F., Sinagra, G., Castro, F.J., Stuart, G., Vignati, G., Yamazawa, H., Barriales-Villa, R., Garcia-Guereta, L., Adwani, S., Linter, K., Bharucha, T., Garcia-Pavia, P., Siles, A., Rasmussen, T.B., Calcagnino, M., Jones, C.B., De Wilde, H., Kubo, T., Felice, T., Popoiu, A., Mogensen, J., Mathur, S., Centeno, F., Reinhardt, Z., Schouvey, S., O'Mahony, C., Omar, R.Z., Elliott, P.M. and Kaski, J.P.
Circulation Arrhythmia and Electrophysiology 15
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May 2022
Compensatory upregulation of anti-beta-adrenergic receptor antibody levels might prevent heart failure presentation in pediatric myocarditis.
Seidel, F., Scheibenbogen, C., Heidecke, H., Opgen-Rhein, B., Pickardt, T., Klingel, K., Berger, F., Messroghli, D. and Schubert, S.
Frontiers in Pediatrics 10
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28 April 2022
External validation of the HCM Risk-Kids model for predicting sudden cardiac death in childhood hypertrophic cardiomyopathy.
Norrish, G., Qu, C., Field, E., Cervi, E., Khraiche, D., Klaassen, S., Ojala, T.H., Sinagra, G., Yamazawa, H., Marrone, C., Popoiu, A., Centeno, F., Schouvey, S., Olivotto, I., Day, S.M., Colan, S., Rossano, J., Wittekind, S.G., Saberi, S., Russell, M., Helms, A., Ingles, J., Semsarian, C., Elliott, P.M., Ho, C.Y., Omar, R.Z. and Kaski, J.P.
European Journal of Preventive Cardiology 29
(4): 678-686.
30 March 2022
Missense variant E1295K of sodium channel SCN5A associated with recurrent ventricular fibrillation and myocardial inflammation.
Poller, W., Escher, F., Haas, J., Heidecker, B., Schultheiss, H.P., Attanasio, P., Skurk, C., Haghikia, A., Meder, B. and Klaassen, S.
JACC: Case Reports 4
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2 March 2022
Nationwide registry-based analysis of infective endocarditis risk after pulmonary valve replacement.
Stammnitz, Clara, Huscher, Dörte, Bauer, Ulrike M M, Urban, Aleksandra, Nordmeyer, Johannes, Schubert, Stephan, Photiadis, Joachim, Berger, Felix and Klaassen, S.
Journal of the American Heart Association 11
(5): e022231.
18 February 2022
Midwall fibrosis and cardiac mechanics: rigid body rotation is a novel marker of disease severity in pediatric primary dilated cardiomyopathy.
Al-Wakeel-Marquard, N., Seidel, F., Kühnisch, J., Kuehne, T., Berger, F., Messroghli, D.R. and Klaassen, S.
Frontiers in Cardiovascular Medicine 8
: 810005.
17 February 2022
Reduced systolic function and not genetic variants determine outcome in pediatric and adult left ventricular noncompaction cardiomyopathy.
Schultze-Berndt, A., Kühnisch, J., Herbst, C., Seidel, F., Al-Wakeel-Marquard, N., Dartsch, J., Theisen, S., Knirsch, W., Jenni, R., Greutmann, M., Oechslin, E., Berger, F. and Klaassen, S.
Frontiers in Pediatrics 9
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September 2021
Pathogenic variants associated with dilated cardiomyopathy predict outcome in pediatric myocarditis.
Seidel, F., Holtgrewe, M., Al-Wakeel-Marquard, N., Opgen-Rhein, B., Dartsch, J., Herbst, C., Beule, D., Pickardt, T., Klingel, K., Messroghli, D., Berger, F., Schubert, S., Kühnisch, J. and Klaassen, S.
Circulation Genomic and Precision Medicine 14
(4): e003250.
4 August 2021
Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy.
Warnecke, N., Ulmer, B.M., Laufer, S.D., Shibamiya, A., Krämer, E., Neuber, C., Hanke, S., Behrens, C., Loos, M., Münch, J., Kühnisch, J., Klaassen, S., Eschenhagen, T., Patten-Hamel, M., Carrier, L. and Mearini, G.
Stem Cell Research 55
: 102489.
August 2021
Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease.
Audain, E., Wilsdon, A., Breckpot, J., Izarzugaza, J.M., Fitzgerald, T.W., Kahlert, A.K., Sifrim, A., Wünnemann, F., Perez-Riverol, Y., Abdul-Khaliq, H., Bak, M., Bassett, A.S., Benson, W.D., Berger, F., Daehnert, I., Devriendt, K., Dittrich, S., Daubeney, P.E., Garg, V., Hackmann, K., Hoff, K., Hofmann, P., Dombrowsky, G., Pickardt, T., Bauer, U., Keavney, B.D., Klaassen, S., Kramer, H.H., Marshall, C.R., Milewicz, D.M., Lemaire, S., Coselli, J.S., Mitchell, M.E., Tomita-Mitchell, A., Prakash, S.K., Stamm, K., Stewart, A.F.R., Silversides, C.K., Siebert, R., Stiller, B., Rosenfeld, J.A., Vater, I., Postma, A.V., Caliebe, A., Brook, J.D., Andelfinger, G., Hurles, M.E., Thienpont, B., Larsen, L.A. and Hitz, M.P.
PLoS Genetics 17
(7): e1009679.
29 July 2021
Diffuse myocardial fibrosis by T1 mapping is associated with heart failure in pediatric primary dilated cardiomyopathy.
Al-Wakeel-Marquard, N., Seidel, F., Herbst, C., Kühnisch, J., Kuehne, T., Berger, F., Klaassen, S. and Messroghli, D.R.
International Journal of Cardiology 333
: 219-225.
15 June 2021
Association for European Paediatric and Congenital Cardiology recommendations for basic training in paediatric and congenital cardiology 2020.
Heying, R., Albert, D.C., Voges, I., Sendzikaite, S., Sarquella-Brugada, G., Pluchinotta, F., Brzezinska-Rajszys, G., Stein, J.I. and Milanesi, O.
Cardiology in the Young 30
(11): 1572-1587.
November 2020
Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease.
Izarzugaza, J.M.G., Ellesøe, S.G., Doganli, C., Ehlers, N.S., Dalgaard, M.D., Audain, E., Dombrowsky, G., Banasik, K., Sifrim, A., Wilsdon, A., Thienpont, B., Breckpot, J., Gewillig, M., Brook, J.D., Hitz, M.P., Larsen, L.A. and Brunak, S.
Genome Medicine 12
(1): 76.
28 August 2020
Familial recurrent myocarditis triggered by exercise in patients with a truncating variant of the desmoplakin gene.
Poller, W., Haas, J., Klingel, K., Kühnisch, J., Gast, M., Kaya, Z., Escher, F., Kayvanpour, E., Degener, F., Opgen-Rhein, B., Berger, F., Mochmann, H.C., Skurk, C., Heidecker, B., Schultheiss, H.P., Monserrat, L., Meder, B., Landmesser, U. and Klaassen, S.
Journal of the American Heart Association 9
(10): e015289.
18 May 2020
Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3.
Kühnisch, J., Herbst, C., Al-Wakeel-Marquard, N., Dartsch, J., Holtgrewe, M., Baban, A., Mearini, G., Hardt, J., Kolokotronis, K., Gerull, B., Carrier, L., Beule, D., Schubert, S., Messroghli, D., Degener, F., Berger, F. and Klaassen, S.
Clinical Genetics 96
(6): 549-559.
December 2019
Severe heart failure and the need for mechanical circulatory support and heart transplantation in pediatric patients with myocarditis: results from the prospective multicenter registry "MYKKE".
Schubert, S., Opgen‐Rhein, B., Boehne, M., Weigelt, A., Wagner, R., Müller, G., Rentzsch, A., zu Knyphausen, E., Fischer, M., Papakostas, K., Wiegand, G., Ruf, B., Hannes, T., Reineker, K., Kiski, D., Khalil, M., Steinmetz, M., Fischer, G., Pickardt, T., Klingel, K., Messroghli, D.R. and Degener, F.
Pediatric Transplantation 23
(7): e13548.
November 2019
RIKADA study reveals risk factors in pediatric primary cardiomyopathy.
Al-Wakeel-Marquard, N., Degener, F., Herbst, C., Kühnisch, J., Dartsch, J., Schmitt, B., Kuehne, T., Messroghli, D., Berger, F. and Klaassen, S.
Journal of the American Heart Association 8
(15): e012531.
6 August 2019
Biallelic mutation in MYH7 and MYBPC3 leads to severe cardiomyopathy with left ventricular noncompaction phenotype.
Kolokotronis, K., Kühnisch, J., Klopocki, E., Dartsch, J., Rost, S., Huculak, C., Mearini, G., Störk, S., Carrier, L., Klaassen, S. and Gerull, B.
Human Mutation 40
(8): 1101-1114.
August 2019
Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation.
Geissler, S., Textor, M., Stumpp, S., Seitz, S., Lekaj, A., Brunk, S., Klaassen, S., Schinke, T., Klein, C., Mundlos, S., Kornak, U. and Kühnisch, J.
PLoS ONE 13
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7 June 2018
Myokarditis im Kindes- und Jugendalter.
Schubert, S., Messroghli, D., Klaassen, S. and Berger, F.
Kardiologie up2date 13
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2017
The progressive ankyloses protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface.
Seifert, W., Posor, Y., Schu, P., Stenbeck, G., Mundlos, S., Klaassen, S., Nürnberg, P., Haucke, V., Kornak, U. and Kühnisch, J.
Human Molecular Genetics 25
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1 September 2016
Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing.
Sifrim, A., Hitz, M.P., Wilsdon, A., Breckpot, J., Turki, S.H.A., Thienpont, B., McRae, J., Fitzgerald, T.W., Singh, T., Swaminathan, G.J., Prigmore, E., Rajan, D., Abdul-Khaliq, H., Banka, S., Bauer, U.M.M., Bentham, J., Berger, F., Bhattacharya, S., Bu'Lock, F., Canham, N., Colgiu, I.G., Cosgrove, C., Cox, H., Daehnert, I., Daly, A., Danesh, J., Fryer, A., Gewillig, M., Hobson, E., Hoff, K., Homfray, T., Kahlert, A.K., Ketley, A., Kramer, H.H., Lachlan, K., Lampe, A.K., Louw, J.J., Manickara, A.K., Manase, D., McCarthy, K.P., Metcalfe, K., Moore, C., Newbury-Ecob, R., Omer, S.O., Ouwehand, W.H., Park, S.M., Parker, M.J., Pickardt, T., Pollard, M.O., Robert, L., Roberts, D.J., Sambrook, J., Setchfield, K., Stiller, B., Thornborough, C., Toka, O., Watkins, H., Williams, D., Wright, M., Mital, S., Daubeney, P.E.F., Keavney, B., Goodship, J., Abu-Sulaiman, R.M., Klaassen, S., Wright, C.F., Firth, H.V., Barrett, J.C., Devriendt, K., FitzPatrick, D.R., Brook, J.D. and Hurles, M.E.
Nature Genetics 48
(9): 1060-1065.
1 August 2016
Gendiagnostik bei kardiovaskulären Erkrankungen: Positionspapier der Deutschen Gesellschaft für Kardiologie (DGK) und der Deutschen Gesellschaft für Pädiatrische Kardiologie (DGPK) [Molecular diagnostics of cardiovascular diseases: Expert consensus statement by the German Cardiac Society (DGK) and the German Society of Pediatric Cardiology (DGPK)].
Schulze-Bahr, E., Klaassen, S., Abdul-Khaliq, H. and Schunkert, H.
Kardiologe 9
(3): 213-243.
June 2015
Rare variants in NR2F2 cause congenital heart defects in humans.
Al Turki, S., Manickaraj, A.K., Mercer, C.L., Gerety, S.S., Hitz, M.P., Lindsay, S., D'Alessandro, L.C.A., Swaminathan, G.J., Bentham, J., Arndt, A.K., Low, J., Breckpot, J., Gewillig, M., Thienpont, B., Abdul-Khaliq, H., Harnack, C., Hoff, K., Kramer, H.H., Schubert, S., Siebert, R., Toka, O., Cosgrove, C., Watkins, H., Lucassen, A.M., O'Kelly, I.M., Salmon, A.P., Bu'Lock, F.A., Granados-Riveron, J., Setchfield, K., Thornborough, C., Brook, J.D., Mulder, B., Klaassen, S., Bhattacharya, S., Devriendt, K., Fitzpatrick, D.F., Wilson, D.I., Mital, S. and Hurles, M.E.
American Journal of Human Genetics 94
(4): 574-585.
3 April 2014
Outlier-based identification of copy number variations using targeted resequencing in a small cohort of patients with tetralogy of fallot.
Bansal, V., Dorn, C., Grunert, M., Klaassen, S., Hetzer, R., Berger, F. and Sperling, S.R.
PLoS ONE 9
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6 January 2014
Left ventricular non-compaction: prevalence in congenital heart disease.
Stähli, B.E., Gebhard, C., Biaggi, P., Klaassen, S., Valsangiacomo Buechel, E., Attenhofer Jost, C.H., Jenni, R., Tanner, F.C. and Greutmann, M.
International Journal of Cardiology 167
(6): 2477-2481.
1 September 2013
Ebstein anomaly associated with left ventricular noncompaction: an autosomal dominant condition that can be caused by mutations in MYH7.
Vermeer, A.M., van Engelen, K., Postma, A.V., Baars, M.J., Christiaans, I., De Haij, S., Klaassen, S., Mulder, B.J. and Keavney, B.
American Journal of Medical Genetics C 163
(3): 178-184.
August 2013
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.
Arndt, A.K., Schaefer, S., Drenckhahn, J.D., Sabeh, M.K., Plovie, E.R., Caliebe, A., Klopocki, E., Musso, G., Werdich, A.A., Kalwa, H., Heinig, M., Padera, R.F., Wassilew, K., Bluhm, J., Harnack, C., Martitz, J., Barton, P.J., Greutmann, M., Berger, F., Huebner, N., Siebert, R., Kramer, H.H., Cook, S.A., Macrae, C.A. and Klaassen, S.
American Journal of Human Genetics 93
(1): 67-77.
11 July 2013
Value of cardiovascular MR in diagnosing left ventricular non-compaction cardiomyopathy and in discriminating between other cardiomyopathies.
Grothoff, M., Pachowsky, M., Hoffmann, J., Posch, M., Klaassen, S., Lehmkuhl, L. and Gutberlet, M.
European Radiology 22
(12): 2699-2709.
December 2012
Rare copy number variants contribute to congenital left-sided heart disease.
Hitz, M.P., Lemieux-Perreault, L.P., Marshall, C., Feroz-Zada, Y., Davies, R., Yang, S.W., Lionel, A.C., D'Amours, G., Lemyre, E., Cullum, R., Bigras, J.L., Thibeault, M., Chetaille, P., Montpetit, A., Khairy, P., Overduin, B., Klaassen, S., Hoodless, P., Awadalla, P., Hussin, J., Idaghdour, Y., Nemer, M., Stewart, A.F., Boerkoel, C., Scherer, S.W., Richter, A., Dube, M.P. and Andelfinger, G.
PLoS Genetics 8
(9): e1002903.
6 September 2012
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.
Guo, W., Schafer, S., Greaser, M.L., Radke, M.H., Liss, M., Govindarajan, T., Maatz, H., Schulz, H., Lincoln, S.E., Parrish, A.M., Dauksaite, V., Vakeel, P., Klaassen, S., Gerull, B., Thierfelder, L., Regitz-Zagrosek, V., Hacker, T.A., Saupe, K.W., Dec, G.W., Ellinor, P.T., MacRae, C.A., Spallek, B., Fischer, R., Perrot, A., Ozcelik, C., Saar, K., Hubner, N. and Gotthardt, M.
Nature Medicine 18
(5): 766-773.
May 2012
Predictors of adverse outcome in adolescents and adults with isolated left ventricular noncompaction.
Greutmann, M., Mah, M.L., Silversides, C.K., Klaassen, S., Attenhofer Jost, C.H., Jenni, R. and Oechslin, E.N.
American Journal of Cardiology 109
(2): 276-281.
15 January 2012
Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype.
Probst, S., Oechslin, E., Schuler, P., Greutmann, M., Boye, P., Knirsch, W., Berger, F., Thierfelder, L., Jenni, R. and Klaassen, S.
Circulation Cardiovascular Genetics 4
(4): 367-374.
1 August 2011
Mutations in the sarcomere protein gene MYH7 in Ebstein's anomaly.
Postma, A.V., van Engelen, K., van de Meerakker, J., Rahman, T., Probst, S., Baars, M.J., Bauer, U., Pickardt, T., Sperling, S.R., Berger, F., Moorman, A.F., Mulder, B.J., Thierfelder, L., Keavney, B., Goodship, J. and Klaassen, S.
Circulation Cardiovascular Genetics 4
(1): 43-50.
February 2011
Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease.
Gramlich, M., Michely, B., Krohne, C., Heuser, A., Erdmann, B., Klaassen, S., Hudson, B., Magarin, M., Kirchner, F., Todiras, M., Granzier, H., Labeit, S., Thierfelder, L. and Gerull, B.
Journal of Molecular and Cellular Cardiology 47
(3): 352-358.
September 2009
Mutations in sarcomere protein genes in left ventricular noncompaction.
Klaassen, S., Probst, S., Oechslin, E., Gerull, B., Krings, G., Schuler, P., Greutmann, M., Huerlimann, D., Yegitbasi, M., Pons, L., Gramlich, M., Drenckhahn, J.D., Heuser, A., Berger, F., Jenni, R. and Thierfelder, L.
Circulation 117
(22): 2893-2901.
3 June 2008
Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy.
Heuser, A., Plovie, E.R., Ellinor, P.T., Grossmann, K.S., Shin, J.T., Wichter, T., Basson, C.T., Lerman, B.B., Sasse-Klaassen, S., Thierfelder, L., MacRae, C.A. and Gerull, B.
American Journal of Human Genetics 79
(6): 1081-1088.
December 2006
A novel locus for dilated cardiomyopathy, diffuse myocardial fibrosis, and sudden death on chromosome 10q25-26.
Ellinor, P.T., Sasse-Klaassen, S., Probst, S., Gerull, B., Shin, J.T., Toeppel, A., Heuser, A., Michely, B., Yoerger, D.M., Song, B.S., Pilz, B., Krings, G., Coplin, B., Lange, P.E., Dec, G.W., Hennies, H.C., Thierfelder, L. and MacRae, C.A.
Journal of the American College of Cardiology 48
(1): 106-111.
4 July 2006
Identification of a novel frameshift mutation in the giant muscle filament titin in a large Australian family with dilated cardiomyopathy.
Gerull, B., Atherton, J., Geupel, A., Sasse-Klaassen, S., Heuser, A., Frenneaux, M., McNabb, M., Granzier, H., Labeit, S. and Thierfelder, L.
Journal of Molecular Medicine 84
(6): 478-483.
June 2006
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B., Heuser, A., Wichter, T., Paul, M., Basson, C.T., McDermott, D.A., Lerman, B.B., Markowitz, S.M., Ellinor, P.T., MacRae, C.A., Peters, S., Grossmann, K.S., Drenckhahn, J., Michely, B., Sasse-Klaassen, S., Birchmeier, W., Dietz, R., Breithardt, G., Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36
(11): 1162-1164.
November 2004
Novel gene locus for autosomal dominant left ventricular noncompaction maps to chromosome 11p15.
Sasse-Klaassen, S., Probst, S., Gerull, B., Oechslin, E., Nuernberg, P., Heuser, A., Jenni, R., Hennies, H.C. and Thierfelder, L.
Circulation 109
(22): 2720-2723.
8 June 2004
Isolated noncompaction of the left ventricular myocardium in the adult is an autosomal dominant disorder in the majority of patients.
Sasse-Klaassen, S., Gerull, B., Oechslin, E., Jenni, R. and Thierfelder, L.
American Journal of Medical Genetics A 119A
(2): 162-167.
1 June 2003
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.
Gerull, B., Gramlich, M., Atherton, J., McNabb, M., Trombitas, K., Sasse-Klaassen, S., Seidman, J.G., Seidman, C., Granzier, H., Labeit, S., Frenneaux, M. and Thierfelder, L.
Nature Genetics 30
(2): 201-204.
February 2002
Book Section
Infectious cardiac diseases in children.
Klaassen, S., Seidel, F., Dalinghaus, M., Salaets, T. and Heying, R.
In:
Pediatric cardiology: fetal, pediatric, and adult congenital heart diseases.
Springer, Cham, 1-31.
ISBN 978-3-030-42937-9
30 September 2023
Infectious cardiac diseases in children; Sabine Klaassen, Franziska Seidel, Michiel Dalinghaus, Thomas Salaets, Ruth Heying.
Klaassen, S., Seidel, F., Dalinghaus, M., Salaets, T. and Heying, R.
In:
Pediatric cardiology : fetal, pediatric, and adult congenital heart diseases.
Springer, Cham.
ISBN 978-3-030-42937-9
21 July 2023
The genetic landscape of cardiomyopathies.
Gerull, B., Klaassen, S. and Brodehl, A.
In:
Genetic Causes of Cardiac Disease.
Cardiac and Vascular Biology, 7
(7).
Springer, Cham, 45-91.
ISBN 978-3-030-27370-5
28 November 2019
Left ventricular noncompaction.
Hoedemaekers, Y.M. and Klaassen, S.
In:
Clinical Cardiogenetics.
Springer, Cham, 113-135.
ISBN 978-3-319-44202-0
2 December 2016
Focused Review: Ventricular noncompaction: an update.
Klaassen, S.
In:
Braunwald's Heart Disease: a textbook of cardiovascular medicine.
Saunders, Philadelphia, Pa., Chapter 65.
ISBN 978-1-416-04104-7
2008
Review
Gendiagnostik bei kardiovaskulären Erkrankungen.
Schulze-Bahr, E., Klaassen, S., Gerull, B., von Kodolitsch, Y., Landmesser, U., Rieß, O., Meder, B. and Schunkert, H.
Kardiologie 17
: 300-349.
September 2023
Left ventricular noncompaction in children: the role of genetics, morphology, and function for outcome.
Klaassen, S., Kühnisch, J., Schultze-Berndt, A. and Seidel, F.
Journal of Cardiovascular Development and Disease 9
(7): 206.
30 June 2022
Ebstein's anomaly may be caused by mutations in the sarcomere protein gene MYH7.
van Engelen, K., Postma, A.V., van de Meerakker, J.B.A., Roos-Hesselink, J.W., Helderman-van den Enden, A.T.J.M., Vliegen, H.W., Rahman, T., Baars, M.J.H., Sels, J.W., Bauer, U., Pickardt, T., Sperling, S.R., Moorman, A.F.M., Keavney, B., Goodship, J., Klaassen, S. and Mulder, B.J.
Netherlands Heart Journal 21
(3): 113-117.
March 2013
Letter
Severe heart failure in the setting of inflammatory cardiomyopathy with likely pathogenic titin variant.
Mueller, M., Zwinger, L., Klaassen, S., Poller, W., Monserrat Iglesias, L., Pablo Ochoa, J., Klingel, K., Landmesser, U. and Heidecker, B.
International Journal of Cardiology (IJC) Heart & Vasculature 39
: 100969.
April 2022
Editorial
Left ventricular noncompaction is a myocardial phenotype: cardiomyopathy - yes or no?
Oechslin, E., Jenni, R. and Klaassen, S.
Canadian Journal of Cardiology 37
(3): 366-369.
March 2021
Left ventricular noncompaction: phenotype in an integrated model of cardiomyopathy?
Oechslin, E. and Klaassen, S.
Journal of the American College of Cardiology 73
(13): 1612-1615.
1 April 2019
Positionspapier Kardiovaskulaere Erkrankungen: Gendiagnostik bei kardiovaskulaeren Erkrankungen [Position paper of cardiovascular disease : genetic diagnostics in cardiovascular diseases].
Schulze-Bahr, E., Klaassen, S., Abdul-Khaliq, H. and Schunkert, H.
Deutsche Medizinische Wochenschrift 140
(20): 1538.
October 2015
Malformations of the left ventricle: what comes first: form or function?
Klaassen, S.
Circulation Cardiovascular Genetics 8
(4): 537-540.
August 2015
This list was generated on Sat Dec 21 12:45:09 2024 UTC.