Browse by Research Team

Advances in Experimental Medicine and Biology

Thomsen-Friedenreich antigen: the "hidden" tumor antigen.
Goletz, S., Cao, Y., Danielczyk, A., Ravn, P., Schoeber, U. and Karsten, U.
Advances in Experimental Medicine and Biology 535 : 147-162. 1 January 2003

Alcohol

Impaired immunoglobulin M production by incubation of hybridoma cells with ethanol.
Muehlbauer, E., Karsten, U., Rottmann, M. and Rommelspacher, H.
Alcohol 24 (3): 179-187. 1 January 2001

Anticancer Research

Development of monoclonal and polyclonal antibodies and an ELISA for the determination of glycodelin in human serum, amniotic fluid and cystic fluid of benign and malignant ovarian tumors.
Jeschke, U., Bischof, A., Speer, R., Briese, V., Richter, D.U., Bergemann, C., Mylonas, I., Shabani, N., Friese, K. and Karsten, U.
Anticancer Research 25 (3): 1581-1589. 1 January 2005

Expression of the Thomsen-Friedenreich (TF) tumor antigen in human abort placentas.
Richter, D.U., Jeschke, U., Bergemann, C., Makovitzky, J., Luthen, F., Karsten, U. and Briese, V.
Anticancer Research 25 (3 A): 1675-1678. 1 January 2005

Archives of Gynecology and Obstetrics

Glycodelin A and differentiation of first trimester trophoblast cells in vitro.
Jeschke, U., Richter, D.U., Reimer, T., Bergemann, C., Briese, V., Karsten, U., Mylonas, I., Kupka, M.S., Wiest, I. and Friese, K.
Archives of Gynecology and Obstetrics 272 (2): 151-159. 1 August 2005

Biochemistry

Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability.
Waseem, A., Karsten, U., Leigh, I.M., Purkis, P., Waseem, N.H. and Lane, E.B.
Biochemistry 43 (5): 1283-1295. 1 January 2004

Breast Cancer Research and Treatment

Prognostic impact of Thomsen-Friedenreich tumor antigen and disseminated tumor cells in the bone marrow of breast cancer patients.
Schindlbeck, C., Jeschke, U., Schulze, S., Karsten, U., Janni, W., Rack, B., Krajewski, S., Sommer, H. and Friese, K.
Breast Cancer Research and Treatment 101 (1): 17-25. January 2007

Cancer Immunology Immunotherapy

The Thomsen-Friedenreich disaccharide as antigen for in vivo tumor targeting with multivalent scFvs.
Ravn, P., Stahn, R., Danielczyk, A., Faulstich, D., Karsten, U. and Goletz, S.
Cancer Immunology Immunotherapy 56 (9): 1345-1357. September 2007

PankoMab: a potent new generation anti-tumour MUC1 antibody.
Danielczyk, A., Stahn, R., Faulstich, D., Loeffler, A., Maerten, A., Karsten, U. and Goletz, S.
Cancer Immunology Immunotherapy 55 (11): 1337-1347. November 2006

Cancer Research

Enhanced binding of antibodies to the DTR motif of MUC1 tandem repeat peptide is mediated by site-specific glycosylation.
Karsten, U., Diotel, C., Klich, G., Paulsen, H., Goletz, S., Mueller, S. and Hanisch, F.G.
Cancer Research 58 (12): 2541-2549. 15 June 1998

Clinical and Experimental Metastasis

Immunomagnetic enrichment of disseminated tumor cells in bone marrow and blood of breast cancer patients by the Thomsen-Friedenreich-Antigen.
Schindlbeck, C., Stellwagen, J., Jeschke, U., Karsten, U., Rack, B., Janni, W., Jueckstock, J., Tulusan, A., Sommer, H. and Friese, K.
Clinical and Experimental Metastasis 25 (3): 233-240. May 2008

European Journal of Cell Biology

Involvement of the Gal β1 - 3GalNAcβ structure in the recognition of apoptotic bodies by THP-1 cells.
Rapoport, E., Khaidukov, S., Baidina, O., Bojenko, V., Moiseeva, E., Pasynina, G., Karsten, U., Nifantev, N., LePendu, J. and Bovin, N.
European Journal of Cell Biology 82 (6): 295-302. June 2003

Genes Chromosomes & Cancer

Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.
Seitz, S., Wassmuth, P., Plaschke, J., Schackert, H.K., Karsten, U., Santibanez-Koref, M.F., Schlag, P.M. and Scherneck, S.
Genes Chromosomes & Cancer 37 (1): 29-35. May 2003

Glycobiology

Binding patterns of DTR-specific antibodies reveal a glycosylation-conditioned tumor-specific epitope of the epithelial mucin (MUC1).
Karsten, U., Serttas, N., Paulsen, H., Danielczyk, A. and Goletz, S.
Glycobiology 14 (8): 681-692. 1 August 2004

The fucosylated histo-blood group antigens H type 2 (blood group O, CD173) and Lewis Y (CD174) are expressed on CD34+ hematopoietic progenitors but absent on mature lymphocytes.
Cao, Y., Merling, A., Karsten, U. and Schwartz-Albiez, R.
Glycobiology 11 (8): 677-683. 1 January 2001

A sequencing strategy for the localization of O-glycosylation sites of MUC1 tandem repeats by PSD-MALDI mass spectrometry.
Goletz, S., Thiede, B., Hanisch, F.G., Schultz, M., Mueller, S., Peter-Katalinic, J., Seitz, O. and Karsten, U.
Glycobiology 7 : 881-896. 1 January 1997

Histochemistry and Cell Biology

Binding of galectin-1 (gal-1) to the Thomsen-Friedenreich (TF) antigen on trophoblast cells and inhibition of proliferation of trophoblast tumor cells in vitro by gal-1 or an anti-TF antibody.
Jeschke, U., Karsten, U., Wiest, I., Schulze, S., Kuhn, C., Friese, K. and Walzel, H.
Histochemistry and Cell Biology 126 (4): 437-444. October 2006

Characterisation of disseminated tumor cells in the bone marrow of breast cancer patients by the Thomsen-Friedenreich tumor antigen.
Schindlbeck, C., Jeschke, U., Schulze, S., Karsten, U., Janni, W., Rack, B., Sommer, H. and Friese, K.
Histochemistry and Cell Biology 123 (6): 631-637. 1 January 2005

Expression of the Thomsen-Friedenreich antigen and of its putative carrier protein mucin 1 in the human placenta and in trophoblast cells in vitro.
Jeschke, U., Richter, D.U., Hammer, A., Briese, V., Friese, K. and Karsten, U.
Histochemistry and Cell Biology 117 (3): 219-226. 1 January 2002

Binding patterns of 51 monoclonal antibodies to peptide and carbohydrate epitopes of the epithelial mucin (MUC1) on tissue sections of adenolymphomas of the parotid (Warthin's tumours): role of epitope masking by glycans.
Cao, Y. and Karsten, U.
Histochemistry and Cell Biology 115 (4): 349-356. 1 January 2001

Thomsen-Friedenreich-related carbohydrate antigens in normal adult human tissues: a systematic and comparative study.
Cao, Y., Stosiek, P., Springer, G.F. and Karsten, U.
Histochemistry and Cell Biology 106 (2): 197-207. 1 August 1996

International Immunopharmacology

Detection, isolation and partial characterization of an immunostimulating glycoprotein from Rhodococcus fascians.
Butschak, G., Karsten, U., Schelhaas, U., Ott, H., Emmendoerffer, A., Niemeyer, B., Helmholz, H. and Goletz, S.
International Immunopharmacology 6 (9): 1441-1450. September 2006

International Journal of Cancer

Expression of CD175 (Tn), CD175s (sialosyl-Tn) and CD176 (Thomsen-Friedenreich antigen) on malignant human hematopoietic cells.
Cao, Y., Merling, A., Karsten, U., Goletz, S., Punzel, M., Kraft, R., Butschak, G. and Schwartz-Albiez, R.
International Journal of Cancer 123 (1): 89-99. 1 July 2008

Journal of Molecular Biology

Multivalent scFv display of phagemid repertoires for the selection of carbohydrate-specific antibodies and its application to the Thomsen-Friedenreich antigen.
Ravn, P., Danielczyk, A., Jensen, K.B., Kristensen, P., Christensen, P.A., Larsen, M., Karsten, U. and Goletz, S.
Journal of Molecular Biology 343 (4): 985-996. 29 October 2004

Selection of large diversities of antiidiotypic antibody fragments by phage display.
Goletz, S., Christensen, P.A., Kristensen, P., Blohm, D., Tomlinson, I., Winter, G. and Karsten, U.
Journal of Molecular Biology 315 (5): 1087-1097. 1 January 2002

Journal of Perinatal Medicine

Stimulation of hCG protein and mRNA in first trimester villous cytotrophoblast cells in vitro by glycodelin A.
Jeschke, U., Karsten, U., Reimer, T., Richter, D.U., Bergemann, C., Briese, V., Mylonas, L. and Friese, K.
Journal of Perinatal Medicine 33 (3): 212-218. 1 January 2005

Oncology

Immunoreactivity of monoclonal antibody BW835 represents a marker of progression and prognosis in early gastric cancer.
Baldus, S.E., Zirbes, T., Glossmann, J., Fromm, S., Hanisch, F.G., Moenig, S.P., Schroeder, W., Schneider, P.M., Flucke, U., Karsten, U., Thiele, J., Hoelscher, A.H. and Dienes, H.P.
Oncology 61 (2): 147-155. 1 January 2001

Tumor Biology

What makes MUC1 a tumor antigen?
Karsten, U., von Mensdorff-Pouilly, S. and Goletz, S.
Tumor Biology 26 (4): 217-220. 6 July 2005

Isolation and characterization of Thomsen-Friedenreich-specific antibodies from human serum.
Butschak, G. and Karsten, U.
Tumor Biology 23 (3): 113-122. May 2002

Inhibition of liver metastases from neuraminidase-treated colon 26 cells by an anti-thomsen-friedenreich-specific monoclonal antibody.
Shigeoka, H., Karsten, U. and Okuno, K.
Tumor Biology 20 : 139-146. 1 January 1999

Immunohistochemical characterization of a panel of 56 antibodies with normal human small intestine, colon, and breast tissues.
Cao, Y., Karsten, U. and Hilgers, J.
Tumor Biology 19 (suppl 1) : 88-99. 1 January 1998

Virchows Archiv

Fast and sensitive immunodetection of carcinoma cells in sentinel nodes.
Karsten, U. and Stosiek, P.
Virchows Archiv 440 (3): 325-329. 1 January 2002