Article

Enhancing maturation of human neuromuscular organoids via electrical stimulation.
Moysidou, Chrysanthi-Maria ORCID: https://orcid.org/0000-0001-9809-2764, Afonso Martins, Inês ORCID: https://orcid.org/0009-0007-6147-2975, El-Shimy, Ismail Amr ORCID: https://orcid.org/0000-0003-0587-5140, Bicci, Iacopo ORCID: https://orcid.org/0000-0001-6994-3857, Cea, Donatella, Bukas, Christina, Mekki, Isra, Rusu, Mara-Camelia ORCID: https://orcid.org/0000-0002-8369-3580, Nebol, Aylin ORCID: https://orcid.org/0000-0002-2962-9836, Lahmann, Ines ORCID: https://orcid.org/0000-0003-0640-4519, Piraud, Marie, Klotzsch, Enrico ORCID: https://orcid.org/0000-0002-7577-9042 and Gouti, Mina ORCID: https://orcid.org/0000-0001-7422-1605
Advanced Science : e22762. 22 June 2026 (In Press)

Direct specification of lymphatic endothelium from mesenchymal progenitors.
Lupu, I.E. ORCID: https://orcid.org/0000-0002-0869-8525, Grainger, D.E. ORCID: https://orcid.org/0000-0003-2277-9089, Kirschnick, N., Weischer, S. ORCID: https://orcid.org/0000-0001-7292-8308, Zhao, E., Martinez-Corral, I., Schoofs, H. ORCID: https://orcid.org/0000-0003-3429-912X, Vanhollebeke, M., Jones, G., Godwin, J., Forrow, A., Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Riley, P.R. ORCID: https://orcid.org/0000-0002-9862-7332, Zobel, T. ORCID: https://orcid.org/0000-0002-2101-8416, Alitalo, K. ORCID: https://orcid.org/0000-0002-7331-0902, Mäkinen, T. ORCID: https://orcid.org/0000-0002-9338-1257, Kiefer, F. ORCID: https://orcid.org/0000-0002-3002-8237 and Stone, O.A. ORCID: https://orcid.org/0000-0002-4695-4569
Nature Cardiovascular Research 4 (1): 45-63. January 2025

Sensor macrophages derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs.
Abdin, S.M. ORCID: https://orcid.org/0009-0003-2534-5726, Mansel, F., Rafiei Hashtchin, A. ORCID: https://orcid.org/0000-0002-6917-2519, Ackermann, M., Hansen, G., Becker, B., Kick, B., Pham, N., Dietz, H., Schaniel, C., Martin, U., Spreitzer, I. and Lachmann, N.
Biofabrication 16 (3): 035017. July 2024

Canonical and non-canonical integrin-based adhesions dynamically interconvert.
Lukas, F., Matthaeus, C., López-Hernández, T., Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Schultz, N., Lehmann, M. ORCID: https://orcid.org/0000-0002-8370-6353, Puchkov, D. ORCID: https://orcid.org/0000-0001-8341-4847, Pielage, J. ORCID: https://orcid.org/0000-0002-5115-5884, Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993 and Maritzen, T. ORCID: https://orcid.org/0000-0003-4993-0340
Nature Communications 15 (1): 2093. 7 March 2024

Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A., Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Nguyen, L.V.N., Rost, B.R. ORCID: https://orcid.org/0000-0003-1906-0081, García-Pérez, A. ORCID: https://orcid.org/0000-0002-2168-5542, Lelievre, N., Merritt-Garza, M.E., Phan, H.C, Bassell, G.J. ORCID: https://orcid.org/0000-0003-2622-0127, Rossoll, W. ORCID: https://orcid.org/0000-0002-9622-541X, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Schmitz, D. ORCID: https://orcid.org/0000-0003-2741-5241 and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
Nature Communications 14 (1): 8043. 19 December 2023

Organoids as tools for fundamental discovery and translation - a Keystone Symposia report.
Cable, J., Lutolf, M.P., Fu, J., Park, S.E., Apostolou, A., Chen, S., Song, C.J., Spence, J.R., Liberali, P., Lancaster, M., Meier, A.B., Pek, N.M.Q., Wells, J.M., Capeling, M.M., Uzquiano, A., Musah, S., Huch, M., Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Hombrink, P., Quadrato, G. and Urenda, J.P.
Annals of the New York Academy of Sciences 1518 (1): 196-208. December 2022

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation.
Blassberg, R. ORCID: https://orcid.org/0000-0001-8577-3544, Patel, H. ORCID: https://orcid.org/0000-0003-2707-7940, Watson, T., Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Metzis, V., Delás, M.J. ORCID: https://orcid.org/0000-0001-9727-9068 and Briscoe, J. ORCID: https://orcid.org/0000-0002-1020-5240
Nature Cell Biology 24 (5): 633-644. May 2022

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Urzi, A., Vidal, R. ORCID: https://orcid.org/0000-0003-4217-2014, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Kabuss, L., Hube, I., Gazzerro, E. ORCID: https://orcid.org/0000-0003-2428-0302, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693 and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
Cell Stem Cell 26 (2): 172-186. 6 February 2020

Nervous system regionalization entails axial allocation before neural differentiation.
Metzis, V., Steinhauser, S., Pakanavicius, E., Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Stamataki, D., Ivanovitch, K., Watson, T., Rayon, T., Mousavy Gharavy, S.N., Lovell-Badge, R., Luscombe, N.M. and Briscoe, J.
Cell 175 (4): 1105-1118. 1 November 2018

Human axial progenitors generate trunk neural crest cells in vitro.
Frith, T.J.R. ORCID: https://orcid.org/0000-0002-6078-5466, Granata, I., Wind, M., Stout, E., Thompson, O., Neumann, K., Stavish, D., Heath, P.R., Ortmann, D., Hackland, J.O.S. ORCID: https://orcid.org/0000-0001-7087-9995, Anastassiadis, K. ORCID: https://orcid.org/0000-0002-9814-0559, Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Briscoe, J. ORCID: https://orcid.org/0000-0002-1020-5240, Wilson, V. ORCID: https://orcid.org/0000-0003-4182-5159, Johnson, S.L., Placzek, M., Guarracino, M.R., Andrews, P.W. and Tsakiridis, A. ORCID: https://orcid.org/0000-0002-2184-2990
eLife 7 : e35786. 10 August 2018

G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
Pusapati, G.V., Kong, J.H., Patel, B.B., Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Sagner, A., Sircar, R., Luchetti, G., Ingham, P.W., Briscoe, J. and Rohatgi, R.
Science Signaling 11 (516): eaao5749. 6 February 2018

A gene regulatory network balances neural and mesoderm specification during vertebrate trunk development.
Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Delile, J., Stamataki, D., Wymeersch, F.J., Huang, Y., Kleinjung, J., Wilson, V. and Briscoe, J.
Developmental Cell 41 (3): 243-261. 8 May 2017

Neural progenitors adopt specific identities by directly repressing all alternative progenitor transcriptional programs.
Kutejova, E., Sasai, N., Shah, A., Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605 and Briscoe, J.
Developmental Cell 36 (6): 639-653. 21 March 2016

In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Tsakiridis, A., Wymeersch, F.J., Huang, Y., Kleinjung, J., Wilson, V. and Briscoe, J.
PLoS Biology 12 (8): e1001937. 26 August 2014

Directed neural differentiation of mouse embryonic stem cells is a sensitive system for the identification of novel Hox gene effectors.
Bami, M., Episkopou, V., Gavalas, A. and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
PLoS ONE 6 (5): e20197. 26 May 2011

Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates.
Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Briscoe, J. and Gavalas, A.
Stem Cells 29 (5): 858-870. May 2011

Hoxb1 controls cell fate specification and proliferative capacity of neural stem and progenitor cells.
Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605 and Gavalas, A.
Stem Cells 26 (8): 1985-1997. August 2008

Novel effectors of directed and Ngn3-mediated differentiation of mouse embryonic stem cells into endocrine pancreas progenitors.
Serafimidis, I., Rakatzi, I., Episkopou, V., Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605 and Gavalas, A.
Stem Cells 26 (1): 3-16. January 2008

Chromatin signatures of pluripotent cell lines.
Azuara, V., Perry, P., Sauer, S., Spivakov, M., Jorgensen, H.F., John, R.M., Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Casanova, M., Warnes, G., Merkenschlager, M. and Fisher, A.G.
Nature Cell Biology 8 (5): 532-538. May 2006

Book Section

Hox genes and stem cells.
Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605 and Gavalas, A.
In: HOX Gene Expression. Springer, 111-120. ISBN 978-0-387-68989-0 2007

Review

A new era in neuromuscular junction research: current advances in self-organized and assembled in vitro models.
Nebol, A. ORCID: https://orcid.org/0000-0002-2962-9836 and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
Current Opinion in Genetics & Development 87 : 102229. August 2024

Once upon a dish: the next frontier in engineering multicellular systems.
Huch, M. ORCID: https://orcid.org/0000-0002-1545-5265 and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
Development 149 (20): dev200744. 15 October 2022

Humane neuromuskuläre Organoide - Anwendung und Perspektive [Human neuromuscular organoids - Application and perspective].
Faustino Martins, J.M., Nguyen, L.V.N. and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
BIOspektrum 27 (2): 135-138. March 2021

The route to spinal cord cell types: a tale of signals and switches.
Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605, Metzis, V. and Briscoe, J.
Trends in Genetics 31 (6): 282-289. June 2015

Preprint

Guided maturation of human neuromuscular organoids via electrical stimulation.
Moysidou, Chrysanthi-Maria ORCID: https://orcid.org/0000-0001-9809-2764, Afonso Martins, Inês ORCID: https://orcid.org/0009-0007-6147-2975, El-Shimy, Ismail Amr ORCID: https://orcid.org/0000-0003-0587-5140, Cea, Donatella, Bukas, Christina, Mekki, Isra, Lahmann, Ines ORCID: https://orcid.org/0000-0003-0640-4519, Piraud, Marie, Klotzsch, Enrico and Gouti, Mina ORCID: https://orcid.org/0000-0001-7422-1605
bioRxiv : 2025.10.30.685366. 31 October 2025

Dataset

Bidirectional editing unveils gene interactions in human brain evolution.
Vitriolo, Alessandro ORCID: https://orcid.org/0000-0002-1462-8064 and Skaros, Adrianos ORCID: https://orcid.org/0000-0001-7261-3162
[Dataset] 31 December 2025