Browse by Research Team

2025

Direct specification of lymphatic endothelium from mesenchymal progenitors.
Lupu, I.E., Grainger, D.E., Kirschnick, N., Weischer, S., Zhao, E., Martinez-Corral, I., Schoofs, H., Vanhollebeke, M., Jones, G., Godwin, J., Forrow, A., Lahmann, I., Riley, P.R., Zobel, T., Alitalo, K., Mäkinen, T., Kiefer, F. and Stone, O.A.
Nature Cardiovascular Research 4 (1): 45-63. January 2025

2024

A new era in neuromuscular junction research: current advances in self-organized and assembled in vitro models.
Nebol, A. and Gouti, M.
Current Opinion in Genetics & Development 87 : 102229. August 2024

Sensor macrophages derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs.
Abdin, S.M., Mansel, F., Rafiei Hashtchin, A., Ackermann, M., Hansen, G., Becker, B., Kick, B., Pham, N., Dietz, H., Schaniel, C., Martin, U., Spreitzer, I. and Lachmann, N.
Biofabrication 16 (3): 035017. July 2024

Canonical and non-canonical integrin-based adhesions dynamically interconvert.
Lukas, F., Matthaeus, C., López-Hernández, T., Lahmann, I., Schultz, N., Lehmann, M., Puchkov, D., Pielage, J., Haucke, V. and Maritzen, T.
Nature Communications 15 (1): 2093. 7 March 2024

2023

Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A., Lahmann, I., Nguyen, L.V.N., Rost, B.R., García-Pérez, A., Lelievre, N., Merritt-Garza, M.E., Phan, H.C, Bassell, G.J., Rossoll, W., Diecke, S., Kunz, S., Schmitz, D. and Gouti, M.
Nature Communications 14 (1): 8043. 19 December 2023

2022

Organoids as tools for fundamental discovery and translation - a Keystone Symposia report.
Cable, J., Lutolf, M.P., Fu, J., Park, S.E., Apostolou, A., Chen, S., Song, C.J., Spence, J.R., Liberali, P., Lancaster, M., Meier, A.B., Pek, N.M.Q., Wells, J.M., Capeling, M.M., Uzquiano, A., Musah, S., Huch, M., Gouti, M., Hombrink, P., Quadrato, G. and Urenda, J.P.
Annals of the New York Academy of Sciences 1518 (1): 196-208. December 2022

Once upon a dish: the next frontier in engineering multicellular systems.
Huch, M. and Gouti, M.
Development 149 (20): dev200744. 15 October 2022

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation.
Blassberg, R., Patel, H., Watson, T., Gouti, M., Metzis, V., Delás, M.J. and Briscoe, J.
Nature Cell Biology 24 (5): 633-644. May 2022

2021

Humane neuromuskuläre Organoide - Anwendung und Perspektive [Human neuromuscular organoids - Application and perspective].
Faustino Martins, J.M., Nguyen, L.V.N. and Gouti, M.
BIOspektrum 27 (2): 135-138. March 2021

2020

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C., Urzi, A., Vidal, R., Kunz, S., Ruffault, P.L., Kabuss, L., Hube, I., Gazzerro, E., Birchmeier, C., Spuler, S., Sauer, S. and Gouti, M.
Cell Stem Cell 26 (2): 172-186. 6 February 2020

2018

Nervous system regionalization entails axial allocation before neural differentiation.
Metzis, V., Steinhauser, S., Pakanavicius, E., Gouti, M., Stamataki, D., Ivanovitch, K., Watson, T., Rayon, T., Mousavy Gharavy, S.N., Lovell-Badge, R., Luscombe, N.M. and Briscoe, J.
Cell 175 (4): 1105-1118. 1 November 2018

Human axial progenitors generate trunk neural crest cells in vitro.
Frith, T.J.R., Granata, I., Wind, M., Stout, E., Thompson, O., Neumann, K., Stavish, D., Heath, P.R., Ortmann, D., Hackland, J.O.S., Anastassiadis, K., Gouti, M., Briscoe, J., Wilson, V., Johnson, S.L., Placzek, M., Guarracino, M.R., Andrews, P.W. and Tsakiridis, A.
eLife 7 : e35786. 10 August 2018

G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
Pusapati, G.V., Kong, J.H., Patel, B.B., Gouti, M., Sagner, A., Sircar, R., Luchetti, G., Ingham, P.W., Briscoe, J. and Rohatgi, R.
Science Signaling 11 (516): eaao5749. 6 February 2018

2017

A gene regulatory network balances neural and mesoderm specification during vertebrate trunk development.
Gouti, M., Delile, J., Stamataki, D., Wymeersch, F.J., Huang, Y., Kleinjung, J., Wilson, V. and Briscoe, J.
Developmental Cell 41 (3): 243-261. 8 May 2017

2016

Neural progenitors adopt specific identities by directly repressing all alternative progenitor transcriptional programs.
Kutejova, E., Sasai, N., Shah, A., Gouti, M. and Briscoe, J.
Developmental Cell 36 (6): 639-653. 21 March 2016

2015

The route to spinal cord cell types: a tale of signals and switches.
Gouti, M., Metzis, V. and Briscoe, J.
Trends in Genetics 31 (6): 282-289. June 2015

2014

In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
Gouti, M., Tsakiridis, A., Wymeersch, F.J., Huang, Y., Kleinjung, J., Wilson, V. and Briscoe, J.
PLoS Biology 12 (8): e1001937. 26 August 2014

2011

Directed neural differentiation of mouse embryonic stem cells is a sensitive system for the identification of novel Hox gene effectors.
Bami, M., Episkopou, V., Gavalas, A. and Gouti, M.
PLoS ONE 6 (5): e20197. 26 May 2011

Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates.
Gouti, M., Briscoe, J. and Gavalas, A.
Stem Cells 29 (5): 858-870. May 2011

2008

Hoxb1 controls cell fate specification and proliferative capacity of neural stem and progenitor cells.
Gouti, M. and Gavalas, A.
Stem Cells 26 (8): 1985-1997. August 2008

Novel effectors of directed and Ngn3-mediated differentiation of mouse embryonic stem cells into endocrine pancreas progenitors.
Serafimidis, I., Rakatzi, I., Episkopou, V., Gouti, M. and Gavalas, A.
Stem Cells 26 (1): 3-16. January 2008

2007

Hox genes and stem cells.
Gouti, M. and Gavalas, A.
In: HOX Gene Expression. Springer, 111-120. ISBN 978-0-387-68989-0 2007

2006

Chromatin signatures of pluripotent cell lines.
Azuara, V., Perry, P., Sauer, S., Spivakov, M., Jorgensen, H.F., John, R.M., Gouti, M., Casanova, M., Warnes, G., Merkenschlager, M. and Fisher, A.G.
Nature Cell Biology 8 (5): 532-538. May 2006