2024
Cell states in cancer: drivers, passengers, and trailers.
Gargiulo, G., Serresi, M. and Marine, J.C.
Cancer Discovery 14
(4): 610-614.
4 April 2024
Clonal dominance defines metastatic dissemination in pancreatic cancer.
Ho, I.L., Li, C.Y., Wang, F., Zhao, L., Liu, J., Yen, E.Y., Dyke, C.A., Shah, R., Liu, Z., Çetin, A.O., Chu, Y., Citron, F., Attanasio, S., Corti, D., Darbaniyan, F., Del Poggetto, E., Loponte, S., Liu, J., Soeung, M., Chen, Z., Jiang, S., Jiang, H., Inoue, A., Gao, S., Deem, A., Feng, N., Ying, H., Kim, M., Giuliani, V., Genovese, G., Zhang, J., Futreal, A., Maitra, A., Heffernan, T., Wang, L., Do, K.A., Gargiulo, G., Draetta, G., Carugo, A., Lin, R. and Viale, A.
Science Advances 10
(11): eadd9342.
15 March 2024
Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes.
Company, C., Schmitt, M.J., Dramaretska, Y., Serresi, M., Kertalli, S., Jiang, B., Yin, J.A., Aguzzi, A., Barozzi, I. and Gargiulo, G.
Nature Communications 15
(1): 897.
5 February 2024
2023
Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses.
Jiang, B., Schmitt, M.J., Rand, U., Company, C., Dramaretska, Y., Grossmann, M., Serresi, M., Cicin-Sain, L. and Gargiulo, G.
Science Advances 9
(25): eadf4975.
23 June 2023
2022
Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S., Company, C., Song, K., Lowenstein, E.D., Riedel, L., Birchmeier, C., Gargiulo, G. and Zampieri, N.
Nature Communications 13
(1): 6867.
11 November 2022
Optimization of synthetic molecular reporters for a mesenchymal glioblastoma transcriptional program by integer programming.
Breitenbach, T., Schmitt, M.J. and Dandekar, T.
Bioinformatics 38
(17): 4162-4171.
1 September 2022
2021
Cannabidiol converts NF(κ)B into a tumor suppressor in glioblastoma with defined antioxidative properties.
Volmar, M.N.M., Cheng, J., Alenezi, H., Richter, S., Haug, A., Hassan, Z., Goldberg, M., Li, Y., Hou, M., Herold-Mende, C., Maire, C.L., Lamszus, K., Flüh, C., Held-Feindt, J., Gargiulo, G., Topping, G.J., Schilling, F., Saur, D., Schneider, G., Synowitz, M., Schick, J.A., Kälin, R.E. and Glass, R.
Neuro-Oncology 23
(11): 1898-1910.
November 2021
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1.
Marques, C., Unterkircher, T., Kroon, P., Oldrini, B., Izzo, A., Dramaretska, Y., Ferrarese, R., Kling, E., Schnell, O., Nelander, S., Wagner, E.F., Bakiri, L., Gargiulo, G., Carro, M.S. and Squatrito, M.
eLife 10
: e64846.
17 August 2021
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.
Ho, J.S., Di Tullio, F., Schwarz, M., Low, D., Incarnato, D., Gay, F., Tabaglio, T., Zhang, J.X., Wollmann, H., Chen, L., An, O., Chan, T.H.M., Hall Hickman, A., Zheng, S., Roudko, V., Chen, S., Karz, A., Ahmed, M., He, H.H., Greenbaum, B.D., Oliviero, S., Serresi, M., Gargiulo, G., Mann, K.M., Hernando, E., Mulholland, D., Marazzi, I., Wee, D.K.B. and Guccione, E.
eLife 10
: e59654.
2 June 2021
Phenotypic mapping of pathologic cross-talk between glioblastoma and innate immune cells by synthetic genetic tracing.
Schmitt, M.J., Company, C., Dramaretska, Y., Barozzi, I., Göhrig, A., Kertalli, S., Großmann, M., Naumann, H., Sánchez-Bailón, M.P., Hulsman, D., Glass, R., Squatrito, M., Serresi, M. and Gargiulo, G.
Cancer Discovery 11
(3): 754-777.
March 2021
Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition.
Serresi, M., Kertalli, S., Li, L., Schmitt, M.J., Dramaretska, Y., Wierikx, J., Hulsman, D. and Gargiulo, G.
Science Advances 7
(9): eabd7974.
24 February 2021
The relevance of the SH2 domain for c-Src functionality in triple-negative breast cancer cells.
Mayoral-Varo, V., Sánchez-Bailón, M.P., Calcabrini, A., García-Hernández, M., Frezza, V., Martín, M.E., González, V.M. and Martín-Pérez, J.
Cancers 13
(3): 462.
26 January 2021
2020
USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells.
van den Berk, P., Lancini, C., Company, C., Serresi, M., Sanchez-Bailon, M.P., Hulsman, D., Pritchard, C., Song, J.Y., Schmitt, M.J., Tanger, E., Popp, O., Mertins, P., Huijbers, I.J., Jacobs, H., van Lohuizen, M., Gargiulo, G. and Citterio, E.
Cell Reports 33
(13): 108533.
29 December 2020
2019
Targeting APLN/APLNR improves antiangiogenic efficiency and blunts proinvasive side effects of VEGFA/VEGFR2 blockade in glioblastoma.
Mastrella, G., Hou, M., Li, M., Stoecklein, V.M., Zdouc, N., Volmar, M.N.M., Miletic, H., Reinhard, S., Herold-Mende, C.C., Kleber, S., Eisenhut, K., Gargiulo, G., Synowitz, M., Vescovi, A.L., Harter, P.N., Penninger, J.M., Wagner, E., Mittelbronn, M., Bjerkvig, R., Hambardzumyan, D., Schüller, U., Tonn, J.C., Radke, J., Glass, R. and Kälin, R.E.
Cancer Research 79
(9): 2298-2313.
May 2019
2018
Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Serresi, M., Siteur, B., Hulsman, D., Company, C., Schmitt, M.J., Lieftink, C., Morris, B., Cesaroni, M., Proost, N., Beijersbergen, R.L., van Lohuizen, M. and Gargiulo, G.
Journal of Experimental Medicine 215
(12): 3115.
3 December 2018
Next-generation in vivo modeling of human cancers.
Gargiulo, G.
Frontiers in Oncology 8
: 429.
October 2018
2016
SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin.
Ferone, G., Song, J.Y., Sutherland, K.D., Bhaskaran, R., Monkhorst, K., Lambooij, J.P., Proost, N., Gargiulo, G. and Berns, A.
Cancer Cell 30
(4): 519-532.
10 October 2016
Polycomb and lung cancer: when the dosage makes the (kind of) poison.
Gargiulo, G., Citterio, E. and Serresi, M.
Molecular & Cellular Oncology 3
(3): e1152345.
May 2016
Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epithelial-mesenchymal transition in non-small-cell lung cancer.
Serresi, M., Gargiulo, G., Proost, N., Siteur, B., Cesaroni, M., Koppens, M., Xie, H., Sutherland, K.D., Hulsman, D., Citterio, E., Orkin, S., Berns, A. and van Lohuizen, M.
Cancer Cell 29
(1): 17-31.
11 January 2016
2014
In vivo shRNA screens in solid tumors.
Gargiulo, G., Serresi, M., Cesaroni, M., Hulsman, D. and van Lohuizen, M.
Nature Protocols 9
(12): 2880-2902.
December 2014
Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.
Lancini, C., van den Berk, P.C.M., Vissers, J.H.A., Gargiulo, G., Song, J.Y., Hulsman, D., Serresi, M., Tanger, E., Blom, M., Vens, C., van Lohuizen, M., Jacobs, H. and Citterio, E.
Journal of Experimental Medicine 211
(9): 1759-1777.
25 August 2014
2013
The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.
Sparmann, A., Xie, Y., Verhoeven, E., Vermeulen, M., Lancini, C., Gargiulo, G., Hulsman, D., Mann, M., Knoblich, J.A. and van Lohuizen, M.
EMBO Journal 32
(11): 1598-1612.
29 May 2013
In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.
Gargiulo, G., Cesaroni, M., Serresi, M., de Vries, N., Hulsman, D., Bruggeman, S.W., Lancini, C. and van Lohuizen, M.
Cancer Cell 23
(5): 660-676.
13 May 2013
2011
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.
Di Micco, R., Sulli, G., Dobreva, M., Liontos, M., Botrugno, O.A., Gargiulo, G., dal Zuffu, R., Matti, V., d'Ario, G., Montani, E., Mercurio, C., Hahn, W.C., Gorgoulis, V., Minucci, S. and d'Adda di Fagagna, F.
Nature Cell Biology 13
(3): 292-302.
March 2011
2009
NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation.
Gargiulo, G., Levy, S., Bucci, G., Romanenghi, M., Fornasari, L., Beeson, K.Y., Goldberg, S.M., Cesaroni, M., Ballarini, M., Santoro, F., Bezman, N., Frige, G., Gregory, P.D., Holmes, M.C., Strausberg, R.L., Pelicci, P.G., Urnov, F.D. and Minucci, S.
Developmental Cell 16
(3): 466-481.
17 March 2009
Epigenomic profiling of cancer cells.
Gargiulo, G. and Minucci, S.
International Journal of Biochemistry and Cell Biology 41
(1): 127-135.
January 2009
2007
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Bracken, A.P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Moench, K., Minucci, S., Porse, B.T., Marine, J.-C., Hansen, K.H. and Helin, K.
Genes & Development 21
(5): 525-530.
1 March 2007
This list was generated on Sat Dec 21 18:53:57 2024 UTC.