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2018

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V. and Rosen, D.B. and Wang, Q. and Gazumyan, A. and Pai, J.A. and Oliveira, T.Y. and Sundaravinayagam, D. and Zhang, W. and Andreani, M. and Keller, L. and Kieffer-Kwon, K.R. and Pękowska, A. and Jung, S. and Driesner, M. and Subbotin, R.I. and Casellas, R. and Chait, B.T. and Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 4 October 2018 (In Press)

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K. and Kranz, A. and Fohgrub, J. and Jolly, A. and Bledau, A.S. and Di Virgilio, M. and Lesche, M. and Dahl, A. and Höfer, T. and Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018

2017

A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y. and Malehmir, M. and Healy, M.E. and Bettermann, K. and Lorentzen, A. and Vucur, M. and Ahuja, A.K. and Böhm, F. and Mertens, J.C. and Shimizu, Y. and Frick, L. and Remouchamps, C. and Mutreja, K. and Kähne, T. and Sundaravinayagam, D. and Wolf, M.J. and Rehrauer, H. and Koppe, C. and Speicher, T. and Padrissa-Altés, S. and Maire, R. and Schattenberg, J.M. and Jeong, J.S. and Liu, Lei and Zwirner, S. and Boger, R. and Hüser, N. and Davis, R.J. and Müllhaupt, B. and Moch, H. and Schulze-Bergkamen, H. and Clavien, P.A. and Werner, S. and Borsig, L. and Luther, S.A. and Jost, P.J. and Weinlich, R. and Unger, K. and Behrens, A. and Hillert, L. and Dillon, C. and Di Virgilio, M. and Wallach, D. and Dejardin, E. and Zender, L. and Naumann, M. and Walczak, H. and Green, D.R. and Lopes, M. and Lavrik, I. and Luedde, T. and Heikenwalder, M. and Weber, A.
Cancer Cell 32 (3): 342-359. 11 September 2017

MAD2L2 promotes open chromatin in embryonic stem cells and derepresses the Dppa3 locus.
Rahjouei, A. and Pirouz, M. and Di Virgilio, M. and Kamin, D. and Kessel, M.
Stem Cell Reports 8 (4): 813-821. 11 April 2017

2015

DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Volk, T. and Pannicke, U. and Reisli, I. and Bulashevska, A. and Ritter, J. and Björkman, A. and Schäffer, A.A. and Fliegauf, M. and Sayar, E.H. and Salzer, U. and Fisch, P. and Pfeifer, D. and Di Virgilio, M. and Cao, H. and Yang, F. and Zimmermann, K. and Keles, S. and Caliskaner, Z. and Güner, S.Ü. and Schindler, D. and Hammarström, L. and Rizzi, M. and Hummel, M. and Pan-Hammarstroem, Q. and Schwarz, K. and Grimbacher, B.
Human Molecular Genetics 24 (25): 7361-7372. 20 December 2015

PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones.
Sander, S. and Chu, V.T. and Yasuda, T. and Franklin, A. and Graf, R. and Calado, D.P. and Li, S. and Imami, K. and Selbach, M. and Di Virgilio, M. and Bullinger, L. and Rajewsky, K.
Immunity 43 (6): 1075-1086. 15 December 2015

An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex.
Kracker, S. and Di Virgilio, M. and Schwartzentruber, J. and Cuenin, C. and Forveille, M. and Deau, M.C. and McBride, K.M. and Majewski, J. and Gazumyan, A. and Seneviratne, S. and Grimbacher, B. and Kutukculer, N. and Herceg, Z. and Cavazzana, M. and Jabado, N. and Nussenzweig, M.C. and Fischer, A. and Durandy, A.
Journal of Allergy and Clinical Immunology 135 (4): 998-1007. April 2015

2013

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Callen, E. and Di Virgilio, M. and Kruhlak, M.J. and Nieto-Soler, M. and Wong, N. and Chen, H.T. and Faryabi, R.B. and Polato, F. and Santos, M. and Starnes, L.M. and Wesemann, D.R. and Lee, J.E. and Tubbs, A. and Sleckman, B.P. and Daniel, J.A. and Ge, K. and Alt, F.W. and Fernandez-Capetillo, O. and Nussenzweig, M.C. and Nussenzweig, A.
Cell 153 (6): 1266-1280. 6 June 2013

Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Di Virgilio, M. and Callen, E. and Yamane, A. and Zhang, W. and Jankovic, M. and Gitlin, A.D. and Feldhahn, N. and Resch, W. and Oliveira, T.Y. and Chait, B.T. and Nussenzweig, A. and Casellas, R. and Robbiani, D.F. and Nussenzweig, M.C.
Science 339 (6120): 711-715. 8 February 2013

2011

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.
Klein, I.A. and Resch, W. and Jankovic, M. and Oliveira, T. and Yamane, A. and Nakahashi, H. and Di Virgilio, M. and Bothmer, A. and Nussenzweig, A. and Robbiani, D.F. and Casellas, R. and Nussenzweig, M.C.
Cell 147 (1): 95-106. 30 September 2011

Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Bothmer, A. and Robbiani, D.F. and Di Virgilio, M. and Bunting, S.F. and Klein, I.A. and Feldhahn, N. and Barlow, J. and Chen, H.T. and Bosque, D. and Callen, E. and Nussenzweig, A. and Nussenzweig, M.C.
Molecular Cell 42 (3): 319-329. 6 May 2011

Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.
Gazumyan, A. and Timachova, K. and Yuen, G. and Siden, E. and Di Virgilio, M. and Woo, E.M. and Chait, B.T. and Reina San-Martin, B. and Nussenzweig, M.C. and McBride, K.M.
Molecular and Cellular Biology 31 (3): 442-429. February 2011

2010

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.
Pavri, R. and Gazumyan, A. and Jankovic, M. and Di Virgilio, M. and Klein, I. and Ansarah-Sobrinho, C. and Resch, W. and Yamane, A. and Reina San-Martin, B. and Barreto, V. and Nieland, T.J. and Root, D.E. and Casellas, R. and Nussenzweig, M.C.
Cell 143 (1): 122-133. 1 October 2010

2009

PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin.
Di Virgilio, M. and Ying, C.Y. and Gautier, J.
DNA Repair 8 (11): 1311-1320. 2 November 2009

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Callen, E. and Jankovic, M. and Wong, N. and Zha, S. and Chen, H.T. and Difilippantonio, S. and Di Virgilio, M. and Heidkamp, G. and Alt, F.W. and Nussenzweig, A. and Nussenzweig, M.
Molecular Cell 34 (3): 285-297. 15 May 2009

2008

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.
Dorsett, Y. and McBride, K.M. and Jankovic, M. and Gazumyan, A. and Thai, T.H. and Robbiani, D.F. and Di Virgilio, M. and Reina San-Martin, B. and Heidkamp, G. and Schwickert, T.A. and Eisenreich, T. and Rajewsky, K. and Nussenzweig, M.C.
Immunity 28 (5): 630-638. 16 May 2008

2005

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11.
Di Virgilio, M. and Gautier, J.
Journal of Cell Biology 171 (5): 765-771. 5 December 2005

2002

Novel pathogenic mechanisms of congenital insensitivity to pain with anhidrosis genetic disorder unveiled by functional analysis of neurotrophic tyrosine receptor kinase type 1/nerve growth factor receptor mutations.
Miranda, C. and Di Virgilio, M. and Selleri, S. and Zanotti, G. and Pagliardini, S. and Pierotti, M.A. and Greco, A.
Journal of Biological Chemistry 277 (8): 6455-6462. 22 February 2002

This list was generated on Wed Nov 14 02:19:37 2018 CET.
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