Browse by Research Team

Advanced Functional Materials

Electroconductive biohybrid hydrogel for enhanced maturation and beating properties of engineered cardiac tissues.
Roshanbinfar, K. and Vogt, L. and Greber, B. and Diecke, S. and Boccaccini, A.R. and Scheibel, T. and Engel, F.B.
Advanced Functional Materials 28 (42): 1803951. October 2018

Arthritis Research & Therapy

Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis.
Lee, J. and Kim, Y. and Yi, H. and Diecke, S. and Kim, J. and Jung, H. and Rim, Y.A. and Jung, S.M. and Kim, M. and Kim, Y.G. and Park, S.H. and Kim, H.Y. and Ju, J.H.
Arthritis Research & Therapy 16 (1): R41. 4 February 2014

Biomedicines

Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E. and Escobar, H. and Sunaga-Franze, D.Y. and Sauer, S. and Diecke, S. and Spuler, S.
Biomedicines 10 (5): 1204. 23 May 2022

Cell

The translational landscape of the human heart.
van Heesch, S. and Witte, F. and Schneider-Lunitz, V. and Schulz, J.F. and Adami, E. and Faber, A. and Kirchner, M. and Maatz, H. and Blachut, S. and Sandmann, C.L. and Kanda, M. and Worth, C.L. and Schafer, S. and Calviello, L. and Merriott, R. and Patone, G. and Hummel, O. and Wyler, E. and Obermayer, B. and Mücke, M. and Lindberg, E.L. and Trnka, F. and Memczak, S. and Schilling, M. and Felkin, L.E. and Barton, P.J.R. and Quaife, N.M. and Vanezis, K. and Diecke, S. and Mukai, M. and Mah, N. and Oh, S.J. and Kurtz, A. and Schramm, C. and Schwinge, D. and Sebode, M. and Harakalova, M. and Asselbergs, F.W. and Vink, A. and de Weger, R.A. and Viswanathan, S. and Widjaja, A.A. and Gärtner-Rommel, A. and Milting, H. and Dos Remedios, C. and Knosalla, C. and Mertins, P. and Landthaler, M. and Vingron, M. and Linke, W.A. and Seidman, J.G. and Seidman, C.E. and Rajewsky, N. and Ohler, U. and Cook, S.A. and Hubner, N.
Cell 178 (1): 242-260. 27 June 2019

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. and Kirchner, M. and Uyar, B. and Cheng, J.Y. and Russo, G. and Hernandez-Miranda, L.R. and Szymborska, A. and Zauber, H. and Rudolph, I.M. and Willnow, T.E. and Akalin, A. and Haucke, V. and Gerhardt, H. and Birchmeier, C. and Kühn, R. and Krauss, M. and Diecke, S. and Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

Cell Reports

Alloimmune responses of humanized mice to human pluripotent stem cell therapeutics.
Kooreman, N.G. and de Almeida, P.E. and Stack, J.P. and Nelakanti, R.V. and Diecke, S. and Shao, N.Y. and Swijnenburg, R.J. and Sanchez-Freire, V. and Matsa, E. and Liu, C. and Connolly, A.J. and Hamming, J.F. and Quax, P.H.A. and Brehm, M.A. and Greiner, D.L. and Shultz, L.D. and Wu, J.C.
Cell Reports 20 (8): 1978-1990. 22 August 2017

Cell Stem Cell

A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals.
Lázaro, J. and Costanzo, M. and Sanaki-Matsumiya, M. and Girardot, C. and Hayashi, M. and Hayashi, K. and Diecke, S. and Hildebrandt, T.B. and Lazzari, G. and Wu, J. and Petkov, S. and Behr, R. and Trivedi, V. and Matsuda, M. and Ebisuya, M.
Cell Stem Cell 30 (7): 938-949.e7. 6 July 2023

Autologous iPSC-based vaccines elicit anti-tumor responses in vivo.
Kooreman, N.G. and Kim, Y. and de Almeida, P.E. and Termglinchan, V. and Diecke, S. and Shao, N.Y. and Wei, T.T. and Yi, H. and Dey, De. and Nelakanti, R. and Brouwer, T.P. and Paik, D.T. and Sagiv-Barfi, I. and Han, A. and Quax, P.H.A. and Hamming, J.F. and Levy, R. and Davis, M.M. and Wu, J.C.
Cell Stem Cell 22 (4): 501-513. 5 April 2018

Cellular Signalling

Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine.
Schwab, K. and Chasapopoulou, Z. and Frahm, S. and Magbagbeolu, M. and Cranston, A. and Harrington, C.R. and Wischik, C.M. and Theuring, F. and Riedel, G.
Cellular Signalling 97 : 110386. September 2022

Circulation

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M. and Mücke, M.B. and Pallien, T. and Markó, L. and Sholokh, A. and Schächterle, C. and Aydin, A. and Kidd, A. and Walter, S. and Esmati, Y. and McMurray, B.J. and Lato, D.F. and Sunaga-Franze, D.Y. and Dierks, P.H. and Flores, B.I.M. and Walker-Gray, R. and Gong, M. and Merticariu, C. and Zühlke, K. and Russwurm, M. and Liu, T. and Batolomaeus, T.U.P. and Pautz, S. and Schelenz, S. and Taube, M. and Napieczynska, H. and Heuser, A. and Eichhorst, J. and Lehmann, M. and Miller, D.C. and Diecke, S. and Qadri, F. and Popova, E. and Langanki, R. and Movsesian, M.A. and Herberg, F.W. and Forslund, S.K. and Müller, D.N. and Borodina, T. and Maass, P.G. and Bähring, S. and Hübner, N. and Bader, M. and Klussmann, E.
Circulation 146 (23): 1758-1778. 6 December 2022

Intronic CRISPR repair in a preclinical model of Noonan syndrome-associated cardiomyopathy.
Hanses, U. and Kleinsorge, M. and Roos, L. and Yigit, G. and Li, Y. and Barbarics, B. and El-Battrawy, I. and Lan, H. and Tiburcy, M. and Hindmarsh, R. and Lenz, C. and Salinas, G. and Diecke, S. and Müller, C. and Adham, I. and Altmüller, J. and Nürnberg, P. and Paul, T. and Zimmermann, W.H. and Hasenfuss, G. and Wollnik, B. and Cyganek, L.
Circulation 142 (11): 1059-1076. 15 September 2020

Microfluidic single-cell analysis of transplanted human induced pluripotent stem cell-derived cardiomyocytes after acute myocardial infarction.
Ong, S.G. and Huber, B.C. and Lee, W.H. and Kodo, K. and Ebert, A.D. and Ma, Y. and Nguyen, P.K. and Diecke, S. and Chen, W.Y. and Wu, J.C.
Circulation 132 (8): 762-771. 25 August 2015

Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
Liang, P. and Lan, F. and Lee, A.S. and Gong, T. and Sanchez-Freire, V. and Wang, Y. and Diecke, S. and Sallam, K. and Knowles, J.W. and Wang, P.J. and Nguyen, P.K. and Bers, D.M. and Robbins, R.C. and Wu, J.C.
Circulation 127 (16): 1677-91. 23 April 2013

Circulation Research

A comprehensive TALEN-based knockout library for generating human induced pluripotent stem cell-based models for cardiovascular diseases.
Karakikes, I. and Termglinchan, V. and Cepeda, D.A. and Lee, J. and Diecke, S. and Hendel, A. and Itzhaki, I. and Ameen, M. and Shrestha, R. and Wu, H. and Ma, N. and Shao, N.Y. and Seeger, T. and Woo, N.A. and Wilson, K.D. and Matsa, E. and Porteus, M.H. and Sebastiano, V. and Wu, J.C.
Circulation Research 120 (10): 1561-1571. 12 May 2017

Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform.
Sharma, A. and Marceau, C. and Hamaguchi, R. and Burridge, P.W. and Rajarajan, K. and Churko, J.M. and Wu, H. and Sallam, K.I. and Matsa, E. and Sturzu, A.C. and Che, Y. and Ebert, A. and Diecke, S. and Liang, P. and Red-Horse, K. and Carette, J.E. and Wu, S.M. and Wu, J.C.
Circulation Research 115 (6): 556-66. 29 August 2014

Clinical Hemorheology and Microcirculation

Human and equine endothelial cells in a live cell imaging scratch assay in vitro.
Rieger, J. and Hopperdietzel, C. and Kaessmeyer, S. and Slosarek, I. and Diecke, S. and Richardson, K. and Plendl, J.
Clinical Hemorheology and Microcirculation 70 (4): 495-509. 2018

Clinical and Translational Medicine

Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyocytes and preclinical drug screening.
El-Battrawy, I. and Lan, H. and Cyganek, L. and Maywald, L. and Zhong, R. and Zhang, F. and Xu, Q. and Lee, J. and Duperrex, E. and Hierlemann, A. and Saguner, A.M. and Duru, F. and Kovacs, B. and Huang, M. and Liao, Z. and Albers, S. and Müller, J. and Dinkel, H. and Rose, L. and Hohn, A. and Yang, Z. and Qiao, L. and Li, Y. and Lang, S. and Kleinsorge, M. and Mügge, A. and Aweimer, A. and Fan, X. and Diecke, S. and Akin, I. and Li, G. and Zhou, X.
Clinical and Translational Medicine 11 (12): e646. 26 December 2021

Current Protocols in Stem Cell Biology

Methods for automated single cell isolation and sub-cloning of human pluripotent stem cells.
Vallone, V.F. and Telugu, N.S. and Fischer, I. and Miller, D. and Schommer, S. and Diecke, S. and Stachelscheid, H.
Current Protocols in Stem Cell Biology 55 (1): e123. December 2020

Simple workflow and comparison of media for hPSC-cardiomyocyte cryopreservation and recovery.
Miller, D.C. and Genehr, C. and Telugu, N.S. and Kurths, S. and Diecke, S.
Current Protocols in Stem Cell Biology 55 (1): e125. December 2020

Developmental Cell

Endogenous retrovirus-derived lncRNA BANCR promotes cardiomyocyte migration in humans and non-human primates.
Wilson, K.D. and Ameen, M. and Guo, H. and Abilez, O.J. and Tian, L. and Mumbach, M.R. and Diecke, S. and Qin, X. and Liu, Y. and Yang, H. and Ma, N. and Gaddam, S. and Cunningham, N.J. and Gu, M. and Neofytou, E. and Prado, M. and Hildebrandt, T.B. and Karakikes, I. and Chang, H.Y. and Wu, J.C.
Developmental Cell 54 (6): 694-709. 28 September 2020

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. and Ofenbauer, A. and Bulut, S.I. and Uyar, B. and Baytek, G. and Sommermeier, A. and Seelk, S. and He, M. and Hirsekorn, A. and Vucicevic, D. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

Disease Models & Mechanisms

Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia.
Kuhrt, L.D. and Motta, E. and Elmadany, N. and Weidling, H. and Fritsche-Guenther, R. and Efe, I.E. and Cobb, O. and Chatterjee, J. and Boggs, L.G. and Schnauß, M. and Diecke, S. and Semtner, M. and Anastasaki, C. and Gutmann, D.H. and Kettenmann, H.
Disease Models & Mechanisms 16 (12): dmm049861. December 2023

EMBO Molecular Medicine

Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?
Ebert, A.D. and Diecke, S. and Chen, I.Y. and Wu, J.C.
EMBO Molecular Medicine 7 (9): 1090-1103. 16 July 2015

Europace

A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes.
El-Battrawy, I. and Albers, S. and Cyganek, L. and Zhao, Z. and Lan, H. and Li, X. and Xu, Q. and Kleinsorge, M. and Huang, M. and Liao, Z. and Zhong, R. and Rudic, B. and Müller, J. and Dinkel, H. and Lang, S. and Diecke, S. and Zimmermann, W.H. and Utikal, J. and Wieland, T. and Borggrefe, M. and Zhou, X. and Akin, I.
Europace 21 (9): 1410-1421. September 2019

European Heart Journal

Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Perea-Gil, I. and Seeger, T. and Bruyneel, A.A.N. and Termglinchan, V. and Monte, E. and Lim, E.W. and Vadgama, N. and Furihata, T. and Gavidia, A.A. and Arthur Ataam, J. and Bharucha, N. and Martinez-Amador, N. and Ameen, M. and Nair, P. and Serrano, R. and Kaur, B. and Feyen, D.A.M. and Diecke, S. and Snyder, M.P. and Metallo, C.M. and Mercola, M. and Karakikes, I.
European Heart Journal 43 (36): 3477-3489. 21 September 2022

Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.
Gu, M. and Mordwinkin, N.M. and Kooreman, N.G. and Lee, J. and Wu, H. and Hu, S. and Churko, J.M. and Diecke, S. and Burridge, P.W. and He, C. and Barron, F.E. and Ong, S.G. and Gold, J.D. and Wu, J.C
European Heart Journal 36 (13): 806-16. 1 April 2015

European Journal of Human Genetics

Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.
Rydzanicz, M. and Wachowska, M. and Cook, E.C. and Lisowski, P. and Kuźniewska, B. and Szymańska, K. and Diecke, S. and Prigione, A. and Szczałuba, K. and Szybińska, A. and Koppolu, A. and Murcia Pienkowski, V. and Kosińska, J. and Wiweger, M. and Kostrzewa, G. and Brzozowska, M. and Domańska-Pakieła, D. and Jurkiewicz, E. and Stawiński, P. and Gromadka, A. and Zielenkiewicz, P. and Demkow, U. and Dziembowska, M. and Kuźnicki, J. and Creamer, T.P. and Płoski, R.
European Journal of Human Genetics 27 (1): 61-69. January 2019

Frontiers in Cell and Developmental Biology

Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay.
Zink, A. and Conrad, J. and Telugu, N.S. and Diecke, S. and Heinz, A. and Wanker, E. and Priller, J. and Prigione, A.
Frontiers in Cell and Developmental Biology 8 : 590540. 5 November 2020

Studying Brugada syndrome with an SCN1B variants in human-induced pluripotent stem cell-derived cardiomyocytes.
El-Battrawy, I. and Müller, J. and Zhao, Z. and Cyganek, L. and Zhong, R. and Zhang, F. and Kleinsorge, M. and Lan, H. and Li, X. and Xu, Q. and Huang, M. and Liao, Z. and Moscu-Gregor, A. and Albers, S. and Dinkel, H. and Lang, S. and Diecke, S. and Zimmermann, W.H. and Utikal, J. and Wieland, T. and Borggrefe, M. and Zhou, X. and Akin, I.
Frontiers in Cell and Developmental Biology 7 : 261. 1 November 2019

Human Gene Therapy

Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of adeno-associated virus vectors.
Westhaus, A. and Cabanes Creus, M. and Dilworth, K.L. and Zhu, E. and Salas, D. and Navarro, R.G. and Amaya, A.K. and Scott, A. and Kwiatek, M. and McCorkindale, A.L. and Hayman, T.E. and Frahm, A. and Perocheau, D. and Tran, B.M. and Vincan, E. and Wong, S.L. and Waters, S.A. and Riddiough, G.E. and Perini, M.V. and Wilson, L.O.W. and Baruteau, J. and Diecke, S. and Gonzalez-Aseguinolaza, G. and Santilli, G. and Thrasher, A.J. and Alexander, I.E. and Lisowski, L.
Human Gene Therapy 34 (7-8): 273-288. April 2023

International Journal of Molecular Sciences

Fluorescence spectroscopy of low-level endogenous ß-adrenergic receptor expression at the plasma membrane of differentiating human iPSC-derived cardiomyocytes.
Gmach, P. and Bathe-Peters, M. and Telugu, N. and Miller, D.C. and Annibale, P.
International Journal of Molecular Sciences 23 (18): 10405. 8 September 2022

A preclinical study on brugada syndrome with a CACNB2 variant using human cardiomyocytes from induced pluripotent stem cells.
Zhong, R. and Schimanski, T. and Zhang, F. and Lan, H. and Hohn, A. and Xu, Q. and Huang, M. and Liao, Z. and Qiao, L. and Yang, Z. and Li, Y. and Zhao, Z. and Li, X. and Rose, L. and Albers, S. and Maywald, L. and Müller, J. and Dinkel, H. and Saguner, A. and Janssen, J.W.G. and Telugu, N.S. and Xi, Y. and Lang, S. and Kleinsorge, M. and Duru, F. and Zhou, X. and Diecke, S. and Cyganek, L. and Akin, I. and El-Battrawy, I.
International Journal of Molecular Sciences 23 (15): 8313. 1 August 2022

Journal of Applied Animal Ethics Research

Conservation research in times of COVID-19 - the rescue of the northern white rhino.
Hildebrandt, T.B. and Holtze, S. and Biasetti, P. and Colleoni, S. and de Mori, B. and Diecke, S. and Göritz, F. and Hayashi, K. and Hayashi, M. and Hermes, R. and Kariuki, L. and Lazzari, G. and Mijele, D. and Mutisya, S. and Ndeereh, D. and Ngulu, S. and Seet, S. and Zwilling, J. and Zywitza, V. and Stejskal, J. and Galli, C.
Journal of Applied Animal Ethics Research 3 (1): 16-37. May 2021

Journal of Biological Chemistry

The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells.
Sharma, A. and Diecke, S. and Zhang, W.Y. and Lan, F. and He, C. and Mordwinkin, N.M. and Chua, K.F. and Wu, J.C.
Journal of Biological Chemistry 288 (25): 18439-47. 21 June 2013

Journal of Clinical Investigation

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J. and Muinjonov, B. and Rosiewicz, K.S. and Diecke, S. and Biese, C. and Schiweck, J. and Chien, C. and Zocholl, D. and Conrad, T. and Paul, F. and Alisch, M. and Siffrin, V.
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

Kidney International

Induced pluripotent stem cell-based disease modeling identifies ligand-induced decay of megalin as a cause of Donnai-Barrow syndrome.
Flemming, J. and Marczenke, M. and Rudolph, I.M. and Nielsen, R. and Storm, T. and Ilsoe Christensen, E. and Diecke, S. and Emma, F. and Willnow, T.E.
Kidney International 98 (1): 159-167. July 2020

Korean Journal of Internal Medicine

Recent technological updates and clinical applications of induced pluripotent stem cells.
Diecke, S. and Jung, S.M. and Lee, J. and Ju, J.H.
Korean Journal of Internal Medicine 29 (5): 547-57. September 2014

Methods in Molecular Biology

Disruptors of AKAP-dependent protein-protein interactions.
Walker-Gray, R. and Pallien, T. and Miller, D.C. and Oder, A. and Neuenschwander, M. and von Kries, J.P. and Diecke, S. and Klussmann, E.
Methods in Molecular Biology 2483 : 117-139. 2022

Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes.
Burridge, P.W. and Diecke, S. and Matsa, E. and Sharma, A. and Wu, H. and Wu, J.C.
Methods in Molecular Biology 1353 : 119-130. 2016

Second generation codon optimized minicircle (CoMiC) for nonviral reprogramming of human adult fibroblasts.
Diecke, S. and Lisowski, L. and Kooreman, N.G. and Wu, J.C.
Methods in Molecular Biology 1181 : 1-13. 1 January 2014

Nature

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.
Lee, J. and Termglinchan, V. and Diecke, S. and Itzhaki, I. and Lam, C.K. and Garg, P. and Lau, E. and Greenhaw, M. and Seeger, T. and Wu, H. and Zhang, J.Z and Chen, X. and Gil, I.P. and Ameen, M. and Sallam, K. and Rhee, J.W. and Churko, J.M. and Chaudhary, R. and Chour, T. and Wang, P.J. and Snyder, M.P. and Chang, H.Y. and Karakikes, I. and Wu, J.C.
Nature 572 (7769): 335-340. 15 August 2019

Nature Biomedical Engineering

Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods.
Churko, J.M. and Lee, J. and Ameen, M. and Gu, M. and Venkatasubramanian, M. and Diecke, S. and Sallam, K. and Im, H. and Wang, G. and Gold, J.D. and Salomonis, N. and Snyder, M.P. and Wu, J.C.
Nature Biomedical Engineering 1 (10): 826-837. October 2017

Nature Communications

Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A. and Lahmann, I. and Nguyen, L.V.N. and Rost, B.R. and García-Pérez, A. and Lelievre, N. and Merritt-Garza, M.E. and Phan, H.C and Bassell, G.J. and Rossoll, W. and Diecke, S. and Kunz, S. and Schmitz, D. and Gouti, M.
Nature Communications 14 (1): 8043. 19 December 2023

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Pentimalli, T.M. and Jüttner, R. and Glažar, P. and Uppal, K. and Bottani, E. and Brunetti, D. and Secker, C. and Zink, A. and Meierhofer, D. and Henke, M.T. and Dey, M. and Ciptasari, U. and Mlody, B. and Hahn, T. and Berruezo-Llacuna, M. and Karaiskos, N. and Di Virgilio, M. and Mayr, J.A. and Wortmann, S.B. and Priller, J. and Gotthardt, M. and Jones, D.P. and Mayatepek, E. and Stenzel, W. and Diecke, S. and Kühn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
Nature Communications 12 (1): 1929. 26 March 2021

Embryos and embryonic stem cells from the white rhinoceros.
Hildebrandt, T.B. and Hermes, R. and Colleoni, S. and Diecke, S. and Holtze, S. and Renfree, M.B. and Stejskal, J. and Hayashi, K. and Drukker, M. and Loi, P. and Göritz, F. and Lazzari, G. and Galli, C.
Nature Communications 9 (1): 2589. 4 July 2018

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.
de Almeida, P.E. and Meyer, E.H. and Kooreman, N.G. and Diecke, S. and Dey, D. and Sanchez-Freire, V. and Hu, S. and Ebert, A. and Odegaard, J. and Mordwinkin, N.M. and Brouwer, T.P. and Lo, D. and Montoro, D.T. and Longaker, M.T. and Negrin, R.S. and Wu, J.C.
Nature Communications 5 : 3903. 30 May 2014

Nature Methods

Chemically defined generation of human cardiomyocytes.
Burridge, P.W. and Matsa, E. and Shukla, P. and Lin, Z.C. and Churko, J.M. and Ebert, A.D. and Lan, F. and Diecke, S. and Huber, B. and Mordwinkin, N.M. and Plews, J.R. and Abilez, O.J. and Cui, B. and Gold, J.D. and Wu, J.C.
Nature Methods 11 (8): 855-60. August 2014

Reproduction

In vitro fertilization program in white rhinoceros.
Hildebrandt, T.B. and Holtze, S. and Colleoni, S. and Hermes, R. and Stejskal, J. and Lekolool, I. and Ndereeh, D. and Omondi, P. and Kariuki, L. and Mijele, D. and Mutisya, S. and Ngulu, S. and Diecke, S. and Hayashi, K. and Lazzari, G. and de Mori, B. and Biasetti, P. and Quaggio, A. and Galli, C. and Goeritz, F.
Reproduction 166 (6): 383-399. 25 October 2023

Reproduction Fertility and Development

Artificially produced gametes in mice, humans and other species.
Hayashi, K. and Galli, C. and Diecke, S. and Hildebrandt, T.B.
Reproduction Fertility and Development 33 (2): 91-101. 8 January 2021

STAR Protocols

ASSURED-optimized CRISPR protocol for knockout/SNP knockin in hiPSCs.
Ludwik, K.A. and Telugu, N. and Schommer, S. and Stachelscheid, H. and Diecke, S.
STAR Protocols 4 (3): 102406. 15 September 2023

High-content analysis of neuronal morphology in human iPSC-derived neurons.
Lickfett, S. and Menacho, C. and Zink, A. and Telugu, N.S. and Beller, M. and Diecke, S. and Cambridge, S. and Prigione, A.
STAR Protocols 3 (3): 101567. 16 September 2022

Science

Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly.
Rizalar, F.S. and Lucht, M.T. and Petzoldt, A. and Kong, S. and Sun, J. and Vines, J.H. and Telugu, N.S. and Diecke, S. and Kaas, T. and Bullmann, T. and Schmied, C. and Löwe, D. and King, J.S. and Cho, W. and Hallermann, S. and Puchkov, D. and Sigrist, S.J. and Haucke, V.
Science 382 (6667): 223-230. 12 October 2023

Science Advances

Robust induction of primordial germ cells of white rhinoceros on the brink of extinction.
Hayashi, M. and Zywitza, V. and Naitou, Y. and Hamazaki, N. and Goeritz, F. and Hermes, R. and Holtze, S. and Lazzari, G. and Galli, C. and Stejskal, J. and Diecke, S. and Hildebrandt, T.B. and Hayashi, K.
Science Advances 8 (49): eabp9683. 9 December 2022

Science Translational Medicine

Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system.
Ebert, A.D. and Kodo, K. and Liang, P. and Wu, H. and Huber, B.C. and Riegler, J. and Churko, J. and Lee, J. and de Almeida, P. and Lan, F. and Diecke, S. and Burridge, P.W. and Gold, J.D. and Mochly-Rosen, D. and Wu, J.C.
Science Translational Medicine 6 (255): 255ra130. 24 September 2014

Scientific Reports

Effects of separated pair housing of female C57BL/6JRj mice on well-being.
Hohlbaum, K. and Merle, R. and Frahm, S. and Rex, A. and Palme, R. and Thöne-Reineke, C. and Ullmann, K.
Scientific Reports 12 (1): 8819. 25 May 2022

Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction.
Zywitza, V. and Rusha, E. and Shaposhnikov, D. and Ruiz-Orera, J. and Telugu, N. and Rishko, V. and Hayashi, M. and Michel, G. and Wittler, L. and Stejskal, J. and Holtze, S. and Göritz, F. and Hermes, R. and Wang, J. and Izsvák, Z. and Colleoni, S. and Lazzari, G. and Galli, C. and Hildebrandt, T.B. and Hayashi, K. and Diecke, S. and Drukker, M.
Scientific Reports 12 (1): 3100. 8 March 2022

Generation of functional cardiomyocytes from the synoviocytes of patients with rheumatoid arthritis via induced pluripotent stem cells.
Lee, J. and Jung, S.M. and Ebert, A.D. and Wu, H. and Diecke, S. and Kim, Y. and Yi, H. and Park, S.H. and Ju, J.H.
Scientific Reports 6 : 32669. 9 September 2016

Stem Cell Research

Generation of an NCS1 gene knockout human induced pluripotent stem cell line using CRISPR/Cas9.
Maierhof, S.K. and Schinke, C. and Cernoch, J. and Hew, L. and Bruske, L.P. and Fernandez Vallone, V. and Fischer, K. and Stachelscheid, H. and Huehnchen, P. and Endres, M. and Diecke, S. and Telugu, N.S. and Boehmerle, W.
Stem Cell Research 73 : 103253. December 2023

Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence.
Miller, D.C. and Lisowski, P. and Genehr, C. and Wanker, E.E. and Priller, J. and Prigione, A. and Diecke, S.
Stem Cell Research 68 : 103056. April 2023

Generation of two mother-child pairs of iPSCs from maternally inherited Leigh syndrome patients with m.8993 T > G and m.9176 T > G MT-ATP6 mutations.
Henke, M.T. and Zink, A. and Diecke, S. and Prigione, A. and Schuelke, M.
Stem Cell Research 67 : 103030. March 2023

Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C. and Lisowski, P. and Lickfett, S. and Mlody, B. and Bünning, M. and Genehr, C. and Ulrich, C. and Wanker, E.E. and Diecke, S. and Priller, J. and Prigione, A.
Stem Cell Research 65 : 102976. December 2022

Generation of 20 human induced pluripotent stem cell lines from patients with focal segmental glomerulosclerosis (FSGS).
Cernoch, J. and Fisch, T. and Fischer, I. and Fischer, K. and Iwanska, A. and Krüger, N. and Küchler, J. and Schaar, C. and Schommer, S. and Telugu, N. and Miller, D. and Fernández Vallone, V. and Kurtz, A. and Reinke, P. and Diecke, S. and Stachelscheid, H.
Stem Cell Research 54 : 102406. July 2021

Cores laboratories: organization for stem cell technology advancement.
Dahéron, L. and Diecke, S. and Healy, L. and D'Souza, S.
Stem Cell Research 53 : 102266. May 2021

Generation of three age and gender matched pairs of human induced pluripotent stem cells derived from myoblasts (MDCi011-A, MDCi012-A, MDCi013-A) and from peripheral blood mononuclear cells (MDCi011-B, MDCi012-B, MDCi013-B) from the same donor.
Metzler, E. and Telugu, N. and Diecke, S. and Spuler, S. and Escobar, H.
Stem Cell Research 48 : 101987. October 2020

Generation of two human induced Pluripotent Stem Cell lines derived from myoblasts (MDCi014-A) and from peripheral blood mononuclear cells (MDCi014-B) from the same donor.
Metzler, E. and Telugu, N. and Diecke, S. and Spuler, S. and Escobar, H.
Stem Cell Research 48 : 101998. October 2020

Stem Cell Reviews and Reports

Improved approach for chondrogenic differentiation of human induced pluripotent stem cells.
Nejadnik, H. and Diecke, S. and Lenkov, O.D. and Chapelin, F. and Donig, J. and Tong, X. and Derugin, N. and Chan, R.C.F. and Gaur, A. and Yang, F. and Wu, J.C. and Daldrup-Link, H.E.
Stem Cell Reviews and Reports 11 (2): 242-253. April 2015

Stem Cells

Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation.
Huber, B.C. and Ransohoff, J.D. and Ransohoff, K.J. and Riegler, J. and Ebert, A. and Kodo, K. and Gong, Y. and Sanchez-Freire, V. and Dey, D. and Kooreman, N.G. and Diecke, S. and Zhang, W.Y. and Odegaard, J. and Hu, S. and Gold, J.D. and Robbins, R.C. and Wu, J.C.
Stem Cells 31 (11): 2354-63. November 2013

Theriogenology

The ART of bringing extinction to a freeze - history and future of species conservation, exemplified by rhinos.
Hildebrandt, T.B. and Hermes, R. and Goeritz, F. and Appeltant, R. and Colleoni, S. and de Mori, B. and Diecke, S. and Drukker, M. and Galli, C. and Hayashi, K. and Lazzari, G. and Loi, P. and Payne, J. and Renfree, M. and Seet, S. and Stejskal, J. and Swegen, A. and Williams, S.A. and Zainuddin, Z.Z. and Holtze, S.
Theriogenology 169 : 76-88. 15 July 2021

Zoo Biology

Rewinding the process of mammalian extinction.
Saragusty, J. and Diecke, S. and Drukker, M. and Durrant, B. and Friedrich Ben-Nun, I. and Galli, C. and Goeritz, F. and Hayashi, K. and Hermes, R. and Holtze, S. and Johnson, S. and Lazzari, G. and Loi, P. and Loring, J.F. and Okita, K. and Renfree, M.B. and Seet, S. and Voracek, T. and Stejskal, J. and Ryder, O.A. and Hildebrandt, T.B.
Zoo Biology 35 (4): 280-292. July 2016

bioRxiv

One gene - two proteins: the C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria.
Fasciani, I. and Petragnano, F. and Wang, Z. and Edwards, R. and Telugu, N. and Pietrantoni, I. and Zauber, H. and Rossi, M. and Zabel, U. and Grieben, M. and Terzenidou, M.E. and Di Gregorio, J. and Pellegrini, C. and Santini, S. and Taddei, A.R. and Poehl, B. and Aringhieri, S. and Aloisi, G. and Marampon, F. and Roman, A. and Diecke, S. and Flati, V. and Giorgi, F. and Amicarelli, F. and Tobin, A.B. and Scarselli, M. and Tokatlidis, K. and Lohse, M.J. and Maggio, R. and Annibale, P.
bioRxiv : 2021.04.13.438299. 26 February 2022

Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay.
Zink, A. and Conrad, J. and Telugu, N.S. and Diecke, S. and Heinz, A. and Wanker, E.E. and Priller, J. and Prigione, A.
bioRxiv : 2020.08.12.237461. 12 August 2020

SURF1 mutations causative of Leigh syndrome impair human neurogenesis.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Juettner, R. and Zink, A. and Mlody, B. and Glazar, P. and Secker, C. and Ciptasari, U.H. and Stenzel, W. and Hahn, T. and Diecke, S. and Priller, J. and Gotthardt, M. and Kuehn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
bioRxiv : 551390. 20 February 2019

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
Kolundzic, E. and Ofenbauer, A. and Uyar, B. and Sommermeier, A. and Seelk, S. and He, M. and Baytek, G. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
bioRxiv : 185116. 6 September 2017

eLife

The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation towards the kidney lineage.
Mansour, F. and Hinze, C. and Telugu, N.S. and Kresoja, J. and Shaheed, I.B. and Mosimann, C. and Diecke, S. and Schmidt-Ott, K.M.
eLife 11 : e80165. 12 October 2022

iScience

Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros.
Zywitza, V. and Frahm, S. and Krüger, N. and Weise, A. and Göritz, F. and Hermes, R. and Holtze, S. and Colleoni, S. and Galli, C. and Drukker, M. and Hildebrandt, T.B. and Diecke, S.
iScience 25 (11): 105414. 18 November 2022