Article

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. ORCID: https://orcid.org/0000-0002-7027-0298, Xie, G. ORCID: https://orcid.org/0000-0002-8286-2987, Singh, M. ORCID: https://orcid.org/0000-0002-8626-5418, Ghanbarian, A.T., Raskó, T., Szvetnik, A., Cai, H., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952, Fuchs, N.V. ORCID: https://orcid.org/0000-0003-4175-0740, Schumann, G.G., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Lorincz, M.C., Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658, Hurst, L.D. and Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384
Nature 516 (7531): 405-409. 18 December 2014

Replicative aging and differentiation potential of human adipose tissue-derived mesenchymal stromal cells expanded in pooled human or fetal bovine serum.
Bieback, K., Hecker, A., Schlechter, T., Hofmann, I., Brousos, N., Redmer, T. ORCID: https://orcid.org/0000-0002-0050-9478, Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Klueter, H., Mueller, A.M. and Becker, M.
Cytotherapy 14 (5): 570-583. May 2012

E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
Redmer, T. ORCID: https://orcid.org/0000-0002-0050-9478, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Grigoryan, T., Quiroga-Negreira, A., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624
EMBO Reports 12 (7): 720-726. 1 July 2011

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R., Sternjak, A., Wend, P., Momma, S., Campos, B., Herrmann, I.M., Graf, D., Mitsiadis, T., Herold-Mende, C., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Synowitz, M., Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V., Durrieu-Gaillard, S., Dumay-Odelot, H., Da Silva, D., Rey, C., Prochazkova, M., Roeder, R.G., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624 and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107 (9): 4176-4181. 2 March 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Paul, F.E. ORCID: https://orcid.org/0000-0001-5181-3122, Cheret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Zurborg, S., Feinberg, K., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Schulz, H. ORCID: https://orcid.org/0000-0002-0226-964X, Peles, E., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J., Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Budczies, J., Kosel, F., Brembeck, F.H., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X, Fichtner, I., Schlag, P.M. and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Gastroenterology 137 (11): 165-175. July 2009

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.
Kaufman, W.L., Kocman, I., Agrawal, V., Rahn, H.P. ORCID: https://orcid.org/0000-0002-5233-3937, Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624 and Gossen, M. ORCID: https://orcid.org/0000-0002-1761-4063
Nucleic Acids Research 36 (17): e111. October 2008

FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells.
Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Quiroga-Negreira, A., Redmer, T. ORCID: https://orcid.org/0000-0002-0050-9478 and Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624
Cells Tissues Organs 188 (1-2): 52-61. July 2008

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells.
James, D., Levine, A.J., Besser, D. and Hemmati-Brivanlou, A.
Development 132 (6): 1273-1282. March 2005

Expression of nodal, lefty-A, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.
Besser, D.
Journal of Biological Chemistry 279 (43): 45076-45084. 1 January 2004

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.
Wolfrum, C., Besser, D., Luca, E. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (20): 11624-11629. 30 September 2003

Independent and cooperative activation of chromosomal c-fos promoter by STAT3.
Yang, E., Lerner, L., Besser, D. and Darnell, J.E.
Journal of Biological Chemistry 278 (18): 15794-15799. 2 May 2003

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Su, F., Overholtzer, M., Besser, D. and Levine, A.J.
Genes & Development 16 (1): 46-57. 2002

Protein kinase B beta/Akt2 plays a specific role in muscle differentiation.
Vandromme, M., Rochat, A., Meier, R., Carnac, G., Besser, D., Hemmings, B.A., Fernandez, A. and Lamb, N.J.
Journal of Biological Chemistry 276 (11): 8173-8179. 16 March 2001

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src.
Wong, B.R., Besser, D., Kim, N., Arron, J.R., Vologodskaia, M., Hanafusa, H. and Choi, Y.
Molecular Cell 4 (6): 1041-1049. December 1999

Transcriptional regulation of the murine urokinase-type plasminogen activator gene in skeletal myoblasts.
Miralles, F., Ibanez-Tallon, I., Parra, M., Crippa, M., Blasi, F., Besser, D., Nagamine, Y. and Munoz-Canoves, P.
Thrombosis and Haemostasis 81 (5): 767-774. May 1999

A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.
Besser, D., Bromberg, J.F., Darnell, J.E. and Hanafusa, H.
Molecular and Cellular Biology 19 (2): 1401-1409. February 1999

Stat3 activation is required for cellular transformation by v-src.
Bromberg, J.F., Horvath, C.M., Besser, D., Lathem, W.W. and Darnell, J.E.
Molecular and Cellular Biology 18 (5): 2553-2558. May 1998

12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells.
El-Shemerly, M.Y., Besser, D., Nagasawa, M. and Nagamine, Y.
Journal of Biological Chemistry 272 (49): 30599-30602. 5 December 1997

Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2.
D'Orazio, D., Besser, D., Marksitzer, R., Kunz, C., Hume, D.A., Kiefer, B. and Nagamine, Y.
Gene 201 (1-2): 179-187. 12 November 1997

Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
Besser, D., Bardelli, A., Didichenko, S., Thelen, M., Comoglio, P.M., Ponzetto, C. and Nagamine, Y.
Oncogene 14 (6): 705-711. 13 February 1997

Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway.
Irigoyen, J.P., Besser, D. and Nagamine, Y.
Journal of Biological Chemistry 272 (3): 1904-1909. 17 January 1997

Signal transduction and the u-PA/u-PAR system.
Besser, D., Verde, P., Nagamine, Y. and Blasi, F.
Fibrinolysis 10 (4): 215-237. July 1996

Activation and nuclear translocation of mitogen-activated protein kinases by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase.
Urich, M., el Shemerly, M.Y., Besser, D., Nagamine, Y. and Ballmer-Hofer, K.
Journal of Biological Chemistry 270 (49): 29286-29292. 8 December 1995

Urokinase-type plasminogen activator gene regulation by polyomavirus middle-T antigen.
Besser, D., Urich, M., Sakaue, M., Messerschmitt, A., Ballmer-Hofer, K. and Nagamine, Y.
Oncogene 11 (11): 2383-2391. 7 December 1995

Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts.
Besser, D., Presta, M. and Nagamine, Y.
Cell Growth & Differentiation 6 (8): 1009-1017. August 1995

DNA methylation inhibits transcription by RNA polymerase III of a tRNA gene, but not of a 5S rRNA gene.
Besser, D., Goetz, F., Schulze-Forster, K., Wagner, H., Kroeger, H. and Simon, D.
FEBS Letters 269 (2): 358-362. 3 September 1990

Review

Mesenchymal stromal cells (MSCs): science and f(r)iction.
Bieback, K., Wuchter, P., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Franke, W., Becker, M., Ott, M., Pacher, M., Ma, N., Stamm, C., Klueter, H., Mueller, A. and Ho, A.D.
Journal of Molecular Medicine 90 (7): 773-782. July 2012

SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction.
Birge, R.B., Knudsen, B.S., Besser, D. and Hanafusa, H.
Genes to Cells 1 (7): 595-613. July 1996

Editorial

Stem cell biology-from basic research to regenerative medicine.
Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624
Journal of Molecular Medicine 90 (7): 731-733. July 2012

Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M. ORCID: https://orcid.org/0000-0001-7094-8188, Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624 and Benitah, S.A.
EMBO Reports 13 (1): 9-11. January 2012