Browse by Journal Title

2024

Soluble ACE2 correlates with severe COVID-19 and can impair antibody responses.
Lebedin, M. and Ratswohl, C. and Garg, A. and Schips, M. and Vazquez Garcia, C. and Spatt, L. and Thibeault, C. and Obermayer, B. and Weiner, J. and Moreno Velásquez, I. and Gerhard, C. and Stubbemann, P. and Hanitsch, L.G. and Pischon, T. and Witzenrath, M. and Sander, L.E. and Kurth, F. and Meyer-Hermann, M. and de la Rosa, K.
iScience 27 (3): 109330. 15 March 2024

SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells.
Kalnytska, O. and Qvist, P. and Kunz, S. and Conrad, T. and Willnow, T.E. and Schmidt, V.
iScience 27 (1): 108725. 19 January 2024

2023

Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain.
Alves-Silva, T. and Húngaro, T.G.R. and Freitas-Lima, L.C. and de Melo Arthur, G. and Arruda, A.C. and Santos, R.B. and Oyama, L.M. and Mori, M.A.S. and Bader, M. and Araujo, R.C.
iScience 26 (12): 108409. 15 December 2023

A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1.
Konrath, F. and Willenbrock, M. and Busse, D. and Scheidereit, C. and Wolf, J.
iScience 26 (10): 107917. 20 October 2023

Similar neural pathways link psychological stress and brain-age in health and multiple sclerosis.
Schulz, M.A. and Hetzer, S. and Eitel, F. and Asseyer, S. and Meyer-Arndt, L. and Schmitz-Hübsch, T. and Bellmann-Strobl, J. and Cole, J.H. and Gold, S.M. and Paul, F. and Ritter, K. and Weygandt, M.
iScience 26 (9): 107679. 15 September 2023

Ablation of collagen XII disturbs joint extracellular matrix organization and causes patellar subluxation.
Zhu, M. and Metzen, F. and Hopkinson, M. and Betz, J. and Heilig, J. and Sodhi, J. and Imhof, T. and Niehoff, A. and Birk, D.E. and Izu, Y. and Krüger, M. and Pitsillides, A. A. and Altmüller, J. and van Osch, G.J.V.M. and Straub, V. and Schreiber, G. and Paulsson, M. and Koch, M. and Brachvogel, B.
iScience 26 (7): 107225. 21 July 2023

Preclinical safety and efficacy of a therapeutic antibody that targets SARS-CoV-2 at the sotrovimab face but is escaped by Omicron.
Kreye, J. and Reincke, S.M. and Edelburg, S. and Jeworowski, L.M. and Kornau, H.C. and Trimpert, J. and Hombach, P. and Halbe, S. and Nölle, V. and Meyer, M. and Kattenbach, S. and Sánchez-Sendin, E. and Schmidt, M.L. and Schwarz, T. and Rose, R. and Krumbholz, A. and Merz, S. and Adler, J.M. and Eschke, K. and Abdelgawad, A. and Schmitz, D. and Sander, L.E. and Janssen, U. and Corman, V.M. and Prüss, H.
iScience 26 (4): 106323. 21 April 2023

Constitutive depletion of brain serotonin differentially affects rats’ social and cognitive abilities.
Alonso, L. and Peeva, P. and Stasko, S. and Bader, M. and Alenina, N. and Winter, Y. and Rivalan, M.
iScience 26 (2): 105998. 17 February 2023

Rapid nuclear deadenylation of mammalian messenger RNA.
Alles, J. and Legnini, I. and Pacelli, M. and Rajewsky, N.
iScience 26 (1): 105878. 20 January 2023

2022

Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros.
Zywitza, V. and Frahm, S. and Krüger, N. and Weise, A. and Göritz, F. and Hermes, R. and Holtze, S. and Colleoni, S. and Galli, C. and Drukker, M. and Hildebrandt, T.B. and Diecke, S.
iScience 25 (11): 105414. 18 November 2022

4-phenylbutyrate restores localization and membrane repair to human dysferlin mutations.
Tominaga, K. and Tominaga, N. and Williams, E.O. and Rufibach, L. and Schöwel, V. and Spuler, S. and Viswanathan, M. and Guarente, L.P.
iScience 25 (1): 103667. 21 January 2022

2021

Reduced mitochondrial respiration in T cells of patients with major depressive disorder.
Gamradt, S. and Hasselmann, H. and Taenzer, A. and Brasanac, J. and Stiglbauer, V. and Sattler, A. and Sajitz-Hermstein, M. and Kierszniowska, S. and Ramien, C. and Nowacki, J. and Mascarell-Maricic, L. and Wingenfeld, K. and Piber, D. and Ströhle, A. and Kotsch, K. and Paul, F. and Otte, C. and Gold, S.M.
iScience 24 (11): 103312. 19 November 2021

Depletion of cardiac cardiolipin synthase alters systolic and diastolic function.
Smeir, E. and Leberer, S. and Blumrich, A. and Vogler, G. and Vasiliades, A. and Dresen, S. and Jaeger, C. and Gloaguen, Y. and Klose, C. and Beule, D. and Schulze, P.C. and Bodmer, R. and Foryst-Ludwig, A. and Kintscher, U.
iScience 24 (11): 103314. 19 November 2021

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.
Ramberger, E. and Sapozhnikova, V. and Kowenz-Leutz, E. and Zimmermann, K. and Nicot, N. and Nazarov, P.V. and Perez-Hernandez, D. and Reimer, U. and Mertins, P. and Dittmar, G. and Leutz, A.
iScience 24 (6): 102686. 25 June 2021

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E. and Mösbauer, K. and Franke, V. and Diag, A. and Gottula, L.T. and Arsiè, R. and Klironomos, F. and Koppstein, D. and Hönzke, K. and Ayoub, S. and Buccitelli, C. and Hoffmann, K. and Richter, A. and Legnini, I. and Ivanov, A. and Mari, T. and Del Giudice, S. and Papies, J. and Praktiknjo, S. and Meyer, T.F. and Müller, M.A. and Niemeyer, D. and Hocke, A. and Selbach, M. and Akalin, A. and Rajewsky, N. and Drosten, C. and Landthaler, M.
iScience 24 (3): 102151. 19 March 2021

Single synapse glutamate imaging reveals multiple levels of release mode regulation in mammalian synapses.
Farsi, Z. and Walde, M. and Klementowicz, A.E. and Paraskevopoulou, F. and Woehler, A.
iScience 24 (1): 101909. 22 January 2021

2020

Divergent transcription of the Nkx2-5 locus generates two enhancer RNAs with opposing functions.
Salamon, I. and Serio, S. and Bianco, S. and Pagiatakis, C. and Crasto, S. and Chiariello, A.M. and Conte, M. and Cattaneo, P. and Fiorillo, L. and Felicetta, A. and di Pasquale, E. and Kunderfranco, P. and Nicodemi, M. and Papait, R. and Condorelli, G.
iScience 23 (9): 101539. 25 September 2020

2019

A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells.
Jin, W. and Mulas, F. and Gaertner, B. and Sui, Y. and Wang, J. and Matta, I. and Zeng, C. and Vinckier, N. and Wang, A. and Nguyen-Ngoc, K.V. and Chiou, J. and Kaestner, K.H. and Frazer, K.A. and Carrano, A.C. and Shih, H.P. and Sander, M.
iScience 21 : 681-694. 22 November 2019

Quantitative proteome landscape of the NCI-60 cancer cell lines.
Guo, T. and Luna, A. and Rajapakse, V.N. and Koh, C.C. and Wu, Z. and Liu, W. and Sun, Y. and Gao, H. and Menden, M.P. and Xu, C. and Calzone, L. and Martignetti, L. and Auwerx, C. and Buljan, M. and Banaei-Esfahani, A. and Ori, A. and Iskar, M. and Gillet, L. and Bi, R. and Zhang, J. and Zhang, H. and Yu, C. and Zhong, Q. and Varma, S. and Schmitt, U. and Qiu, P. and Zhang, Q. and Zhu, Y. and Wild, P.J. and Garnett, M.J. and Bork, P. and Beck, M. and Liu, K. and Saez-Rodriguez, J. and Elloumi, F. and Reinhold, W.C. and Sander, C. and Pommier, Y. and Aebersold, R.
iScience 21 : 664-680. 31 October 2019

Long and repeat-rich intronic sequences favor circular RNA formation under conditions of reduced spliceosome activity.
Wang, M. and Hou, J. and Müller-McNicoll, M. and Chen, W. and Schuman, E.M.
iScience 20 : 237-247. 25 October 2019

PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
Dittmar, G. and Perez Hernandez, D. and Kowenz-Leutz, E. and Kirchner, M. and Kahlert, G. and Wesolowski, R. and Baum, K. and Knoblich, M. and Hofstätter, M. and Muller, A. and Wolf, J. and Reimer, U. and Leutz, A.
iScience 13 : 351-370. 29 March 2019