Browse by Journal Title

2023

PI3K-C2β limits mTORC1 signaling and angiogenic growth.
Kobialka, P. and Llena, J. and Deleyto-Seldas, N. and Munar-Gelabert, M. and Dengra, J.A. and Villacampa, P. and Albinyà-Pedrós, A. and Muixi, L. and Andrade, J. and van Splunder, H. and Angulo-Urarte, A. and Potente, M. and Grego-Bessa, J. and Castillo, S.D. and Vanhaesebroeck, B. and Efeyan, A. and Graupera, M.
Science Signaling 16 (813): eadg1913. November 2023

2021

Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1.
Lo, A. and Holmes, K. and Kamlapurkar, S. and Mundt, F. and Moorthi, S. and Fung, I. and Fereshetian, S. and Watson, J. and Carr, S.A. and Mertins, P. and Berger, A.H.
Science Signaling 14 (711): eabc4520. 30 November 2021

2019

Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells.
Fischer, C. and Metsger, M. and Bauch, S. and Vidal, R. and Böttcher, M. and Grote, P. and Kliem, M. and Sauer, S.
Science Signaling 12 (581): eaao5820. 14 May 2019

2018

G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
Pusapati, G.V. and Kong, J.H. and Patel, B.B. and Gouti, M. and Sagner, A. and Sircar, R. and Luchetti, G. and Ingham, P.W. and Briscoe, J. and Rohatgi, R.
Science Signaling 11 (516): eaao5749. 6 February 2018

2017

Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Frischauf, I. and Litviňuková, M. and Schober, R. and Zayats, V. and Svobodova, B. and Bonhenry, D. and Lunz, V. and Cappello, S. and Tociu, L. and Reha, D. and Stallinger, A. and Hochreiter, A. and Pammer, T. and Butorac, C. and Muik, M. and Groschner, K. and Bogeski, I. and Ettrich, R.H. and Romanin, C. and Schindl, R.
Science Signaling 10 (507): eaao0358. 28 November 2017

Degrons in cancer.
Meszaros, B. and Kumar, M. and Gibson, T.J. and Uyar, B. and Dosztanyi, Z.
Science Signaling 10 (470): eaak9982. 14 March 2017

2014

ALK pERKs up MYCN in neuroblastoma.
Lindner, S. and Henssen, A. and Astrahantseff, K. and Schulte, J.H.
Science Signaling 7 (349): pe27. 28 October 2014

Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes.
Thurley, K. and Tovey, S.C. and Moenke, G. and Prince, V.L. and Meena, A. and Thomas, A.P. and Skupin, A. and Taylor, C.W. and Falcke, M.
Science Signaling 7 (331): ra59. 24 June 2014

KCNQ1, KCNE2, and Na(+)-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability.
Abbott, G.W and Tai, K.K. and Neverisky, D.L. and Hansler, A. and Hu, Z. and Roepke, T.K. and Lerner, D.J. and Chen, Q. and Liu, L. and Zupan, B. and Toth, M. and Haynes, R. and Huang, X. and Demirbas, D. and Buccafusca, R. and Gross, S.S. and Kanda, V.A. and Berry, G.T.
Science Signaling 7 (315): ra22. 4 March 2014

ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics.
Norton, M. and Ng, A.C. and Baird, S. and Dumoulin, A. and Shutt, T. and Mah, N. and Andrade-Navarro, M.A. and McBride, H.M. and Screaton, R.A.
Science Signaling 7 (310): ra10. 28 January 2014

2012

Direct binding between Orai1 and AC8 mediates dynamic interplay between Ca2+ and cAMP signaling.
Willoughby, D. and Everett, K.L. and Halls, M.L. and Pacheco, J. and Skroblin, P. and Vaca, L. and Klussmann, E. and Cooper, D.M.
Science Signaling 5 (219): ra29. 10 April 2012

2011

A directed protein interaction network for investigating intracellular signal transduction.
Vinayagam, A. and Stelzl, U. and Foulle, R. and Plassmann, S. and Zenkner, M. and Timm, J. and Assmus, H.E. and Andrade-Navarro, M.A. and Wanker, E.E.
Science Signaling 4 (189): rs8. 6 September 2011

2010

Regulation of Ras localization by acylation enables a mode of intracellular signal propagation.
Lorentzen, A. and Kinkhabwala, A. and Rocks, O. and Vartak, N. and Bastiaens, P.I.
Science Signaling 3 (140): ra68. 21 September 2010

2008

Linear motif atlas for phosphorylation-dependent signaling.
Miller, M.L. and Jensen, L.J. and Diella, F. and Jorgensen, C. and Tinti, M. and Li, L. and Hsiung, M. and Parker, S.A. and Bordeaux, J. and Sicheritz-Ponten, T. and Olhovsky, M. and Pasculescu, A. and Alexander, J. and Knapp, S. and Blom, N. and Bork, P. and Li, S. and Cesareni, G. and Pawson, T. and Turk, B.E. and Yaffe, M.B. and Brunak, S. and Linding, R.
Science Signaling 1 (35): ra2. 2 September 2008

Geranylgeranylation but not GTP-loading of Rho GTPases determines T cell function.
Waiczies, S. and Bendix, I. and Zipp, F.
Science Signaling 1 (12): pt3. 25 March 2008