Browse by Journal Title

2022

EBAG9 controls CD8(+) T cell memory formation responding to tumor challenge in mice.
Rehm, A., Wirges, A., Hoser, D., Fischer, C., Herda, S., Gerlach, K., Sauer, S., Willimsky, G. and Hoepken, U.E.
JCI Insight 7 (11): e155534. 8 June 2022

2021

Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.
Kaiser, R., Leunig, A., Pekayvaz, K., Popp, O., Joppich, M., Polewka, V., Escaig, R., Anjum, A., Hoffknecht, M.L., Gold, C., Brambs, S., Engel, A., Stockhausen, S., Knottenberg, V., Titova, A., Haji, M., Scherer, C., Muenchhoff, M., Hellmuth, J.C., Saar, K., Schubert, B., Hilgendorff, A., Schulz, C., Kääb, S., Zimmer, R., Hübner, N., Massberg, S., Mertins, P., Nicolai, L. and Stark, K.
JCI Insight 6 (18): e150862. 22 September 2021

Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis.
Cruz-Herranz, A., Oertel, F.C., Kim, K., Cantó, E., Timmons, G., Sin, J.H., Devereux, M., Baker, N., Michel, B., Schubert, R.D., Rani, L., Cordano, C., Baranzini, S.E. and Green, A.J.
JCI Insight 6 (11): e149228. 8 June 2021

Base editing repairs an SGCA mutation in human primary muscle stem cells.
Escobar, H., Krause, A., Keiper, S., Kieshauer, J., Müthel, S., García de Paredes, M., Metzler, E., Kühn, R., Heyd, F. and Spuler, S.
JCI Insight 6 (10): e145994. 24 May 2021

The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
Willmes, D.M., Daniels, M., Kurzbach, A., Lieske, S., Bechmann, N., Schumann, T., Henke, C., El-Agroudy, N.N., Da Costa Goncalves, A.C., Peitzsch, M., Hofmann, A., Kanczkowski, W., Kräker, K., Müller, D.N., Morawietz, H., Deussen, A., Wagner, M., El-Armouche, A., Helfand, S.L., Bornstein, S.R., de Cabo, R., Bernier, M., Eisenhofer, G., Tank, J., Jordan, J. and Birkenfeld, A.L.
JCI Insight 6 (2): 136083. 25 January 2021

2020

Transient enlargement of brain ventricles during relapsing-remitting multiple sclerosis and experimental autoimmune encephalomyelitis.
Millward, J.M., Delgado, P.R., Smorodchenko, A., Boehmert, L., Periquito, J., Reimann, H.M., Prinz, C., Els, A., Scheel, M., Bellmann-Strobl, J., Waiczies, H., Wuerfel, J., Infante-Duarte, C., Chien, C., Kuchling, J., Pohlmann, A., Zipp, F., Paul, F., Niendorf, T. and Waiczies, S.
JCI Insight 5 (21): e140040. 5 November 2020

Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements.
Wang, H., Georgakopoulou, A., Li, C., Liu, Z., Gil, S., Bashyam, A., Yannaki, E., Anagnostopoulos, A., Pande, A., Izsvák, Z., Papayannopoulou, T. and Lieber, A.
JCI Insight 5 (16): e139538. 20 August 2020

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P., Newman, A.G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., Kleinau, G., Derkow, K., Richard, B.C., Schipke, C., Scheidereit, C., Stachelscheid, H., Golenbock, D., Peters, O., Coleman, M., Heppner, F.L., Scheerer, P., Tarabykin, V., Ruprecht, K., Izsvák, Z., Mayer, J. and Lehnardt, S.
JCI Insight 5 (7): e131093. 9 April 2020

2019

Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Vidal, R., Wagner, J.U.G., Braeuning, C., Fischer, C., Patrick, R., Tombor, L., Muhly-Reinholz, M., John, D., Kliem, M., Conrad, T., Guimarães-Camboa, N., Harvey, R., Dimmeler, S. and Sauer, S.
JCI Insight 4 (22): e131092. 14 November 2019

Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
Huang, A., Shinde, P.V., Huang, J., Senff, T., Xu, H.C., Margotta, C., Häussinger, D., Willnow, T.E., Zhang, J., Pandyra, A.A., Timm, J., Weggen, S., Lang, K.S. and Lang, P.A.
JCI Insight 4 (17): e129856. 5 September 2019

Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
Ortiz, M.V., Ahmed, S., Burns, M., Henssen, A.G., Hollmann, T.J., MacArthur, I., Gunasekera, S., Gaewsky, L., Bradwin, G., Ryan, J., Letai, A., He, Y., Naranjo, A., Chi, Y.Y., LaQuaglia, M., Heaton, T., Cifani, P., Dome, J.S., Gadd, S., Perlman, E., Mullen, E., Steen, H. and Kentsis, A.
JCI Insight 4 (15): e127098. 8 August 2019

Prohibitin promotes dedifferentiation and is a potential therapeutic target in neuroblastoma.
MacArthur, I.C., Bei, Y., Garcia, H.D., Ortiz, M.V., Toedling, J., Klironomos, F., Rolff, J., Eggert, A., Schulte, J.H., Kentsis, A. and Henssen, A.G.
JCI Insight 4 (10): e127130. 16 May 2019

2018

Emerging functions of DNA transposases and oncogenic mutators in childhood cancer development.
Henssen, A.G. and Kentsis, A.
JCI Insight 3 (20): 123172. 18 October 2018

Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.
Wilck, N., Markó, L., Balogh, A., Kräker, K., Herse, F., Bartolomaeus, H., Szijártó, I.A., Gollasch, M., Reichhart, N., Strauss, O., Heuser, A., Brockschnieder, D., Kretschmer, A., Lesche, R., Sohler, F., Stasch, J.P., Sandner, P., Luft, F., Müller, D.N., Dechend, R. and Haase, N.
JCI Insight 3 (4): e96006. 22 February 2018