Browse by Journal Title

2022

EBAG9 controls CD8(+) T cell memory formation responding to tumor challenge in mice.
Rehm, A. and Wirges, A. and Hoser, D. and Fischer, C. and Herda, S. and Gerlach, K. and Sauer, S. and Willimsky, G. and Hoepken, U.E.
JCI Insight 7 (11): e155534. 8 June 2022

2021

Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.
Kaiser, R. and Leunig, A. and Pekayvaz, K. and Popp, O. and Joppich, M. and Polewka, V. and Escaig, R. and Anjum, A. and Hoffknecht, M.L. and Gold, C. and Brambs, S. and Engel, A. and Stockhausen, S. and Knottenberg, V. and Titova, A. and Haji, M. and Scherer, C. and Muenchhoff, M. and Hellmuth, J.C. and Saar, K. and Schubert, B. and Hilgendorff, A. and Schulz, C. and Kääb, S. and Zimmer, R. and Hübner, N. and Massberg, S. and Mertins, P. and Nicolai, L. and Stark, K.
JCI Insight 6 (18): e150862. 22 September 2021

Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis.
Cruz-Herranz, A. and Oertel, F.C. and Kim, K. and Cantó, E. and Timmons, G. and Sin, J.H. and Devereux, M. and Baker, N. and Michel, B. and Schubert, R.D. and Rani, L. and Cordano, C. and Baranzini, S.E. and Green, A.J.
JCI Insight 6 (11): e149228. 8 June 2021

Base editing repairs an SGCA mutation in human primary muscle stem cells.
Escobar, H. and Krause, A. and Keiper, S. and Kieshauer, J. and Müthel, S. and García de Paredes, M. and Metzler, E. and Kühn, R. and Heyd, F. and Spuler, S.
JCI Insight 6 (10): e145994. 24 May 2021

The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
Willmes, D.M. and Daniels, M. and Kurzbach, A. and Lieske, S. and Bechmann, N. and Schumann, T. and Henke, C. and El-Agroudy, N.N. and Da Costa Goncalves, A.C. and Peitzsch, M. and Hofmann, A. and Kanczkowski, W. and Kräker, K. and Müller, D.N. and Morawietz, H. and Deussen, A. and Wagner, M. and El-Armouche, A. and Helfand, S.L. and Bornstein, S.R. and de Cabo, R. and Bernier, M. and Eisenhofer, G. and Tank, J. and Jordan, J. and Birkenfeld, A.L.
JCI Insight 6 (2): 136083. 25 January 2021

2020

Transient enlargement of brain ventricles during relapsing-remitting multiple sclerosis and experimental autoimmune encephalomyelitis.
Millward, J.M. and Delgado, P.R. and Smorodchenko, A. and Boehmert, L. and Periquito, J. and Reimann, H.M. and Prinz, C. and Els, A. and Scheel, M. and Bellmann-Strobl, J. and Waiczies, H. and Wuerfel, J. and Infante-Duarte, C. and Chien, C. and Kuchling, J. and Pohlmann, A. and Zipp, F. and Paul, F. and Niendorf, T. and Waiczies, S.
JCI Insight 5 (21): e140040. 5 November 2020

Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements.
Wang, H. and Georgakopoulou, A. and Li, C. and Liu, Z. and Gil, S. and Bashyam, A. and Yannaki, E. and Anagnostopoulos, A. and Pande, A. and Izsvák, Z. and Papayannopoulou, T. and Lieber, A.
JCI Insight 5 (16): e139538. 20 August 2020

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P. and Newman, A.G. and Singh, M. and Hinz, M. and Szczepek, M. and Krüger, C. and Adalbert, R. and Dzaye, O. and Trimbuch, T. and Wallach, T. and Kleinau, G. and Derkow, K. and Richard, B.C. and Schipke, C. and Scheidereit, C. and Stachelscheid, H. and Golenbock, D. and Peters, O. and Coleman, M. and Heppner, F.L. and Scheerer, P. and Tarabykin, V. and Ruprecht, K. and Izsvák, Z. and Mayer, J. and Lehnardt, S.
JCI Insight 5 (7): e131093. 9 April 2020

2019

Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Vidal, R. and Wagner, J.U.G. and Braeuning, C. and Fischer, C. and Patrick, R. and Tombor, L. and Muhly-Reinholz, M. and John, D. and Kliem, M. and Conrad, T. and Guimarães-Camboa, N. and Harvey, R. and Dimmeler, S. and Sauer, S.
JCI Insight 4 (22): e131092. 14 November 2019

Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
Huang, A. and Shinde, P.V. and Huang, J. and Senff, T. and Xu, H.C. and Margotta, C. and Häussinger, D. and Willnow, T.E. and Zhang, J. and Pandyra, A.A. and Timm, J. and Weggen, S. and Lang, K.S. and Lang, P.A.
JCI Insight 4 (17): e129856. 5 September 2019

Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
Ortiz, M.V. and Ahmed, S. and Burns, M. and Henssen, A.G. and Hollmann, T.J. and MacArthur, I. and Gunasekera, S. and Gaewsky, L. and Bradwin, G. and Ryan, J. and Letai, A. and He, Y. and Naranjo, A. and Chi, Y.Y. and LaQuaglia, M. and Heaton, T. and Cifani, P. and Dome, J.S. and Gadd, S. and Perlman, E. and Mullen, E. and Steen, H. and Kentsis, A.
JCI Insight 4 (15): e127098. 8 August 2019

Prohibitin promotes dedifferentiation and is a potential therapeutic target in neuroblastoma.
MacArthur, I.C. and Bei, Y. and Garcia, H.D. and Ortiz, M.V. and Toedling, J. and Klironomos, F. and Rolff, J. and Eggert, A. and Schulte, J.H. and Kentsis, A. and Henssen, A.G.
JCI Insight 4 (10): e127130. 16 May 2019

2018

Emerging functions of DNA transposases and oncogenic mutators in childhood cancer development.
Henssen, A.G. and Kentsis, A.
JCI Insight 3 (20): 123172. 18 October 2018

Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.
Wilck, N. and Markó, L. and Balogh, A. and Kräker, K. and Herse, F. and Bartolomaeus, H. and Szijártó, I.A. and Gollasch, M. and Reichhart, N. and Strauss, O. and Heuser, A. and Brockschnieder, D. and Kretschmer, A. and Lesche, R. and Sohler, F. and Stasch, J.P. and Sandner, P. and Luft, F. and Müller, D.N. and Dechend, R. and Haase, N.
JCI Insight 3 (4): e96006. 22 February 2018