Browse by Journal Title

Article

Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4(+) T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease.
Horn, V., Cancino, C.A., Steinheuer, L.M., Obermayer, B., Fritz, K., Nguyen, A.L., Juhran, K.S., Plattner, C., Bösel, D., Oldenburg, L., Burns, M., Schulz, A.R., Saliutina, M., Mantzivi, E., Lissner, D., Conrad, T., Mashreghi, M.F., Zundler, S., Sonnenberg, E., Schumann, M., Haag, L.M., Beule, D., Flatz, L., Trjanoski, Z., D'Haens, G., Weidinger, C., Mei, H.E., Siegmund, B., Thurley, K. and Hegazy, A.N.
Gastroenterology 28 September 2024 (In Press)

Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M., Terkelsen, T., Bartels, A.S., Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G.I., Fang, X., Mann, M. and Moreira, J.M.A.
Gastroenterology 165 (1): 121-132.e5. July 2023

Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D., Oshima, M., Stange, D.E. and Sigal, M.
Gastroenterology 162 (4): 1067-1087. April 2022

Recurrent frameshift neoantigen vaccine elicits protective immunity with reduced tumor burden and improved overall survival in a Lynch syndrome mouse model.
Gebert, J., Gelincik, O., Oezcan-Wahlbrink, M., Marshall, J.D., Hernandez-Sanchez, A., Urban, K., Long, M., Cortes, E., Tosti, E., Katzenmaier, E.M., Song, Y., Elsaadi, A., Deng, N., Vilar, E., Fuchs, V., Nelius, N., Yuan, Y.P., Ahadova, A., Sei, S., Shoemaker, R.H., Umar, A., Wei, L., Liu, S., Bork, P., Edelmann, W., von Knebel Doeberitz, M., Lipkin, S.M. and Kloor, M.
Gastroenterology 161 (4): 288-1302.e13. October 2021

Simple sugar and sugar-sweetened beverage intake during adolescence and risk of colorectal cancer precursors: adolescent sugar intake and colorectal polyp.
Joh, H.K., Lee, D.H., Hur, J., Nimptsch, K., Chang, Y., Joung, H., Zhang, X., Rezende, L.F.M., Lee, J.E., Ng, K., Chen, Y., Tabung, F.K., Meyerhardt, J.A., Chan, A.T., Pischon, T., Song, M., Fuchs, C.S., Willett, W.C., Cao, Y., Ogino, S., Giovannucci, E. and Wu, K.
Gastroenterology 161 (1): 128-142. July 2021

S100A8 and S100A9 are important for postnatal development of gut microbiota and immune system in mice and infants.
Willers, M., Ulas, T., Völlger, L., Vogl, T., Heinemann, A.S., Pirr, S., Pagel, J., Fehlhaber, B., Halle, O., Schöning, J., Schreek, S., Löber, U., Essex, M., Hombach, P., Graspeuntner, S., Basic, M., Bleich, A., Cloppenborg-Schmidt, K., Künzel, S., Jonigk, D., Rupp, J., Hansen, G., Förster, R., Baines, J.F., Härtel, C., Schultze, J.L., Forslund, S.K., Roth, J. and Viemann, D.
Gastroenterology 159 (6): 2130-2145. December 2020

Combined analysis of metabolomes, proteomes, and transcriptomes of hepatitis C virus-infected cells and liver to identify pathways associated with disease development.
Lupberger, J., Croonenborghs, T., Roca Suarez, A.A., Van Renne, N., Jühling, F., Oudot, M.A., Virzì, A., Bandiera, S., Jamey, C., Meszaros, G., Brumaru, D., Mukherji, A., Durand, S.C., Heydmann, L., Verrier, E.R., El Saghire, H., Hamdane, N., Bartenschlager, R., Fereshetian, S., Ramberger, E., Sinha, R., Nabian, M., Everaert, C., Jovanovic, M., Mertins, P., Carr, S.A., Chayama, K., Dali-Youcef, N., Ricci, R., Bardeesy, N.M., Fujiwara, N., Gevaert, O., Zeisel, M.B., Hoshida, Y., Pochet, N. and Baumert, T.F.
Gastroenterology 157 (2): 537-551. August 2019

Loss of pten and activation of kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice.
Kopp, J.L., Dubois, C.L., Schaeffer, D.F., Samani, A., Taghizadeh, F., Cowan, R.W., Rhim, A.D., Stiles, B.L., Valasek, M. and Sander, M.
Gastroenterology 154 (5): 1509-1523.e5. April 2018

Helicobacter pylori depletes cholesterol in gastric glands to prevent interferon gamma signaling and escape the inflammatory response.
Morey, P., Pfannkuch, L., Pang, E., Boccellato, F., Sigal, M., Imai-Matsushima, A., Dyer, V., Koch, M., Mollenkopf, H.J., Schlaermann, P. and Meyer, T.F.
Gastroenterology 154 (5): 1391-1404. April 2018

Deletion of polycomb repressive complex 2 from mouse intestine causes loss of stem cells.
Koppens, M.A.J., Bounova, G., Gargiulo, G., Tanger, E., Janssen, H., Cornelissen-Steijger, P., Blom, M., Song, J.Y., Wessels, L.F.A. and van Lohuizen, M.
Gastroenterology 151 (4): 684-697. October 2016

T cells engineered to express a T-cell receptor specific for glypican-3 recognize and kill hepatoma cells in vitro and in mice.
Dargel, C., Bassani-Sternberg, M., Hasreiter, J., Zani, F., Bockmann, J.H., Thiele, F., Bohne, F., Wisskirchen, K., Wilde, S., Sprinzl, M.F., Schendel, D.J., Krackhardt, A.M., Uckert, W., Wohlleber, D., Schiemann, M., Stemmer, K., Heikenwälder, M., Busch, D.H., Richter, G., Mann, M. and Protzer, U.
Gastroenterology 149 (4): 1042-1052. October 2015

Helicobacter pylori activates and expands Lgr5(+) stem cells through direct colonization of the gastric glands.
Sigal, M., Rothenberg, M.E., Logan, C.Y., Lee, J.Y., Honaker, R.W., Cooper, R.L., Passarelli, B., Camorlinga, M., Bouley, D.M., Alvarez, G., Nusse, R., Torres, J. and Amieva, M.R.
Gastroenterology 148 (7): 1392-1404. June 2015

T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelop proteins control virus replication in mice.
Krebs, K., Böttinger, N., Huang, L.R., Chmielewski, M., Arzberger, S., Gasteiger, G., Jäger, C., Schmitt, E., Bohne, F., Aichler, M., Uckert, W., Abken, H., Heikenwalder, M., Knolle, P. and Protzer, U.
Gastroenterology 145 (2): 456-465. August 2013

CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.
Nakamoto, N., Ebinuma, H., Kanai, T., Chu, P.S., Ono, Y., Mikami, Y., Ojiro, K., Lipp, M., Love, P.E., Saito, H. and Hibi, T.
Gastroenterology 142 (2): 366-376. February 2012

Luminal CD4 + T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation.
Nemoto, Y., Kanai, T., Shinohara, T., Ito, T., Nakamura, T., Okamoto, R., Tsuchiya, K., Lipp, M., Eishi, Y. and Watanabe, M.
Gastroenterology 141 (6): 2130-2139.e11. December 2011

BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H., Wiese, M., Zatula, N., Grigoryan, T., Dai, Y., Fritzmann, J. and Birchmeier, W.
Gastroenterology 141 (4): 1359-1370. October 2011

Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells.
Carpentier, R., Suñer, R.E., van Hul, N., Kopp, J.L., Beaudry, J.B., Cordi, S., Antoniou, A., Raynaud, P., Lepreux, S., Jacquemin, P., Leclercq, I.A., Sander, M. and Lemaigre, F.P.
Gastroenterology 141 (4): 1432-8, 1438.e1-4. October 2011

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J., Morkel, M., Besser, D., Budczies, J., Kosel, F., Brembeck, F.H., Stein, U., Fichtner, I., Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice.
Giebeler, A., Boekschoten, M.V., Klein, C., Borowiak, M., Birchmeier, C., Gassler, N., Wasmuth, H.E., Mueller, M., Trautwein, C. and Streetz, K.L.
Gastroenterology 137 (1): 297-308. July 2009

Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis.
Nocito, A., Dahm, F., Jochum, W., Jang, J.H., Georgiev, P., Bader, M., Renner, E.L. and Clavien, P.A.
Gastroenterology 133 (2): 608-618. August 2007

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer.
Stein, U., Arlt, F., Walther, W., Smith, J., Waldman, T., Harris, E.D., Mertins, S.D., Heizmann, C.W., Allard, D., Birchmeier, W., Schlag, P.M. and Shoemaker, R.H.
Gastroenterology 131 (5): 1486-1500. November 2006

Functional analysis of complex hepatitis B virus variants associated with development of liver cirrhosis.
Maerschenz, S., Endres, A.S., Brinckmann, A., Heise, T., Kristiansen, G., Nuernberg, P., Krueger, D.H., Guenther, S. and Meisel, H.
Gastroenterology 131 (3): 765-780. September 2006

The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.
Page, A.J., Brierley, S.M., Martin, C.M., Martinez-Salgado, C., Wemmie, J.A., Brennan, T.J., Symonds, E., Omari, T., Lewin, G.R., Welsh, M.J. and Blackshaw, L.A.
Gastroenterology 127 (6): 1739-1747. 1 January 2004

E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice.
Smits, R., Ruiz, P., Diaz-Cano, S., Luz, A., Jagmohan-Changur, S., Breukel, C., Birchmeier, C., Birchmeier, W. and Fodde, R.
Gastroenterology 119 (4): 1045-1053. 1 October 2000

Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction.
Rose, C., Butterworth, R.F., Zayed, J., Normandin, L., Todd, K., Michalak, A., Spahr, L., Huet, P.M. and Pomier-Layrargues, G.
Gastroenterology 117 : 640-644. 1 September 1999

Bombesin receptor gene expression in rat pancreatic acinar AR42J cells: transcriptional regulation by glucocorticoids.
Rosewicz, S., Detjen, K., Kaiser, A., Prosenc, N., Cervos-Navarro, J., Riecken, E.O. and Haller, H.
Gastroenterology 107 (1): 208-218. July 1994

T-cell receptor variable genes and genetic susceptibility to celiac disease: an association and linkage study.
Roschmann, E., Wienker, T.F., Gerok, W. and Volk, B.A.
Gastroenterology 105 : 1790-1796. 1 January 1993

Altered content and distribution of tenascin in colitis, colon adenoma, and colorectal carcinoma.
Riedl, S., Faissner, A., Schlag, P.M., von Herbay, A., Koretz, K. and Moeller, P.
Gastroenterology 103 : 400-406. 1 January 1992

Letter

SPINK1 mutations in chronic pancreatitis.
Witt, H., Hennies, H.C. and Becker, M.
Gastroenterology 120 (4): 1060-1061. March 2001

Editorial

New insights into the cell lineage of pancreatic ductal adenocarcinoma: evidence for tumor stem cells in premalignant lesions?
Kopp, J.L. and Sander, M.
Gastroenterology 146 (1): 24-6. January 2014