Browse by Journal Title

2023

Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M. and Terkelsen, T. and Bartels, A.S. and Coscia, F. and Doll, S. and Zhao, S. and Zhang, Z. and Brünner, N. and Lindebjerg, J. and Madsen, G.I. and Fang, X. and Mann, M. and Moreira, J.M.A.
Gastroenterology 165 (1): 121-132.e5. July 2023

2022

Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D. and Oshima, M. and Stange, D.E. and Sigal, M.
Gastroenterology 162 (4): 1067-1087. April 2022

2021

Recurrent frameshift neoantigen vaccine elicits protective immunity with reduced tumor burden and improved overall survival in a Lynch syndrome mouse model.
Gebert, J. and Gelincik, O. and Oezcan-Wahlbrink, M. and Marshall, J.D. and Hernandez-Sanchez, A. and Urban, K. and Long, M. and Cortes, E. and Tosti, E. and Katzenmaier, E.M. and Song, Y. and Elsaadi, A. and Deng, N. and Vilar, E. and Fuchs, V. and Nelius, N. and Yuan, Y.P. and Ahadova, A. and Sei, S. and Shoemaker, R.H. and Umar, A. and Wei, L. and Liu, S. and Bork, P. and Edelmann, W. and von Knebel Doeberitz, M. and Lipkin, S.M. and Kloor, M.
Gastroenterology 161 (4): 288-1302.e13. October 2021

Simple sugar and sugar-sweetened beverage intake during adolescence and risk of colorectal cancer precursors: adolescent sugar intake and colorectal polyp.
Joh, H.K. and Lee, D.H. and Hur, J. and Nimptsch, K. and Chang, Y. and Joung, H. and Zhang, X. and Rezende, L.F.M. and Lee, J.E. and Ng, K. and Chen, Y. and Tabung, F.K. and Meyerhardt, J.A. and Chan, A.T. and Pischon, T. and Song, M. and Fuchs, C.S. and Willett, W.C. and Cao, Y. and Ogino, S. and Giovannucci, E. and Wu, K.
Gastroenterology 161 (1): 128-142. July 2021

2020

S100A8 and S100A9 are important for postnatal development of gut microbiota and immune system in mice and infants.
Willers, M. and Ulas, T. and Völlger, L. and Vogl, T. and Heinemann, A.S. and Pirr, S. and Pagel, J. and Fehlhaber, B. and Halle, O. and Schöning, J. and Schreek, S. and Löber, U. and Essex, M. and Hombach, P. and Graspeuntner, S. and Basic, M. and Bleich, A. and Cloppenborg-Schmidt, K. and Künzel, S. and Jonigk, D. and Rupp, J. and Hansen, G. and Förster, R. and Baines, J.F. and Härtel, C. and Schultze, J.L. and Forslund, S.K. and Roth, J. and Viemann, D.
Gastroenterology 159 (6): 2130-2145. December 2020

2019

Combined analysis of metabolomes, proteomes, and transcriptomes of hepatitis C virus-infected cells and liver to identify pathways associated with disease development.
Lupberger, J. and Croonenborghs, T. and Roca Suarez, A.A. and Van Renne, N. and Jühling, F. and Oudot, M.A. and Virzì, A. and Bandiera, S. and Jamey, C. and Meszaros, G. and Brumaru, D. and Mukherji, A. and Durand, S.C. and Heydmann, L. and Verrier, E.R. and El Saghire, H. and Hamdane, N. and Bartenschlager, R. and Fereshetian, S. and Ramberger, E. and Sinha, R. and Nabian, M. and Everaert, C. and Jovanovic, M. and Mertins, P. and Carr, S.A. and Chayama, K. and Dali-Youcef, N. and Ricci, R. and Bardeesy, N.M. and Fujiwara, N. and Gevaert, O. and Zeisel, M.B. and Hoshida, Y. and Pochet, N. and Baumert, T.F.
Gastroenterology 157 (2): 537-551. August 2019

2018

Loss of pten and activation of kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice.
Kopp, J.L. and Dubois, C.L. and Schaeffer, D.F. and Samani, A. and Taghizadeh, F. and Cowan, R.W. and Rhim, A.D. and Stiles, B.L. and Valasek, M. and Sander, M.
Gastroenterology 154 (5): 1509-1523.e5. April 2018

Helicobacter pylori depletes cholesterol in gastric glands to prevent interferon gamma signaling and escape the inflammatory response.
Morey, P. and Pfannkuch, L. and Pang, E. and Boccellato, F. and Sigal, M. and Imai-Matsushima, A. and Dyer, V. and Koch, M. and Mollenkopf, H.J. and Schlaermann, P. and Meyer, T.F.
Gastroenterology 154 (5): 1391-1404. April 2018

2016

Deletion of polycomb repressive complex 2 from mouse intestine causes loss of stem cells.
Koppens, M.A.J. and Bounova, G. and Gargiulo, G. and Tanger, E. and Janssen, H. and Cornelissen-Steijger, P. and Blom, M. and Song, J.Y. and Wessels, L.F.A. and van Lohuizen, M.
Gastroenterology 151 (4): 684-697. October 2016

2015

T cells engineered to express a T-cell receptor specific for glypican-3 recognize and kill hepatoma cells in vitro and in mice.
Dargel, C. and Bassani-Sternberg, M. and Hasreiter, J. and Zani, F. and Bockmann, J.H. and Thiele, F. and Bohne, F. and Wisskirchen, K. and Wilde, S. and Sprinzl, M.F. and Schendel, D.J. and Krackhardt, A.M. and Uckert, W. and Wohlleber, D. and Schiemann, M. and Stemmer, K. and Heikenwälder, M. and Busch, D.H. and Richter, G. and Mann, M. and Protzer, U.
Gastroenterology 149 (4): 1042-1052. October 2015

Helicobacter pylori activates and expands Lgr5(+) stem cells through direct colonization of the gastric glands.
Sigal, M. and Rothenberg, M.E. and Logan, C.Y. and Lee, J.Y. and Honaker, R.W. and Cooper, R.L. and Passarelli, B. and Camorlinga, M. and Bouley, D.M. and Alvarez, G. and Nusse, R. and Torres, J. and Amieva, M.R.
Gastroenterology 148 (7): 1392-1404. June 2015

2014

New insights into the cell lineage of pancreatic ductal adenocarcinoma: evidence for tumor stem cells in premalignant lesions?
Kopp, J.L. and Sander, M.
Gastroenterology 146 (1): 24-6. January 2014

2013

T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelop proteins control virus replication in mice.
Krebs, K. and Böttinger, N. and Huang, L.R. and Chmielewski, M. and Arzberger, S. and Gasteiger, G. and Jäger, C. and Schmitt, E. and Bohne, F. and Aichler, M. and Uckert, W. and Abken, H. and Heikenwalder, M. and Knolle, P. and Protzer, U.
Gastroenterology 145 (2): 456-465. August 2013

2012

CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.
Nakamoto, N. and Ebinuma, H. and Kanai, T. and Chu, P.S. and Ono, Y. and Mikami, Y. and Ojiro, K. and Lipp, M. and Love, P.E. and Saito, H. and Hibi, T.
Gastroenterology 142 (2): 366-376. February 2012

2011

Luminal CD4 + T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation.
Nemoto, Y. and Kanai, T. and Shinohara, T. and Ito, T. and Nakamura, T. and Okamoto, R. and Tsuchiya, K. and Lipp, M. and Eishi, Y. and Watanabe, M.
Gastroenterology 141 (6): 2130-2139.e11. December 2011

BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H. and Wiese, M. and Zatula, N. and Grigoryan, T. and Dai, Y. and Fritzmann, J. and Birchmeier, W.
Gastroenterology 141 (4): 1359-1370. October 2011

Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells.
Carpentier, R. and Suñer, R.E. and van Hul, N. and Kopp, J.L. and Beaudry, J.B. and Cordi, S. and Antoniou, A. and Raynaud, P. and Lepreux, S. and Jacquemin, P. and Leclercq, I.A. and Sander, M. and Lemaigre, F.P.
Gastroenterology 141 (4): 1432-8, 1438.e1-4. October 2011

2009

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J. and Morkel, M. and Besser, D. and Budczies, J. and Kosel, F. and Brembeck, F.H. and Stein, U. and Fichtner, I. and Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice.
Giebeler, A. and Boekschoten, M.V. and Klein, C. and Borowiak, M. and Birchmeier, C. and Gassler, N. and Wasmuth, H.E. and Mueller, M. and Trautwein, C. and Streetz, K.L.
Gastroenterology 137 (1): 297-308. July 2009

2007

Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis.
Nocito, A. and Dahm, F. and Jochum, W. and Jang, J.H. and Georgiev, P. and Bader, M. and Renner, E.L. and Clavien, P.A.
Gastroenterology 133 (2): 608-618. August 2007

2006

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer.
Stein, U. and Arlt, F. and Walther, W. and Smith, J. and Waldman, T. and Harris, E.D. and Mertins, S.D. and Heizmann, C.W. and Allard, D. and Birchmeier, W. and Schlag, P.M. and Shoemaker, R.H.
Gastroenterology 131 (5): 1486-1500. November 2006

Functional analysis of complex hepatitis B virus variants associated with development of liver cirrhosis.
Maerschenz, S. and Endres, A.S. and Brinckmann, A. and Heise, T. and Kristiansen, G. and Nuernberg, P. and Krueger, D.H. and Guenther, S. and Meisel, H.
Gastroenterology 131 (3): 765-780. September 2006

2004

The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.
Page, A.J. and Brierley, S.M. and Martin, C.M. and Martinez-Salgado, C. and Wemmie, J.A. and Brennan, T.J. and Symonds, E. and Omari, T. and Lewin, G.R. and Welsh, M.J. and Blackshaw, L.A.
Gastroenterology 127 (6): 1739-1747. 1 January 2004

2001

SPINK1 mutations in chronic pancreatitis.
Witt, H. and Hennies, H.C. and Becker, M.
Gastroenterology 120 (4): 1060-1061. March 2001

2000

E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice.
Smits, R. and Ruiz, P. and Diaz-Cano, S. and Luz, A. and Jagmohan-Changur, S. and Breukel, C. and Birchmeier, C. and Birchmeier, W. and Fodde, R.
Gastroenterology 119 (4): 1045-1053. 1 October 2000

1999

Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction.
Rose, C. and Butterworth, R.F. and Zayed, J. and Normandin, L. and Todd, K. and Michalak, A. and Spahr, L. and Huet, P.M. and Pomier-Layrargues, G.
Gastroenterology 117 : 640-644. 1 September 1999

1994

Bombesin receptor gene expression in rat pancreatic acinar AR42J cells: transcriptional regulation by glucocorticoids.
Rosewicz, S. and Detjen, K. and Kaiser, A. and Prosenc, N. and Cervos-Navarro, J. and Riecken, E.O. and Haller, H.
Gastroenterology 107 (1): 208-218. July 1994

1993

T-cell receptor variable genes and genetic susceptibility to celiac disease: an association and linkage study.
Roschmann, E. and Wienker, T.F. and Gerok, W. and Volk, B.A.
Gastroenterology 105 : 1790-1796. 1 January 1993

1992

Altered content and distribution of tenascin in colitis, colon adenoma, and colorectal carcinoma.
Riedl, S. and Faissner, A. and Schlag, P.M. and von Herbay, A. and Koretz, K. and Moeller, P.
Gastroenterology 103 : 400-406. 1 January 1992