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2024

Cell-mediated exon skipping normalizes dystrophin expression and muscle function in a new mouse model of Duchenne Muscular Dystrophy.
Galli, F. and Bragg, L. and Rossi, M. and Proietti, D. and Perani, L. and Bagicaluppi, M. and Tonlorenzi, R. and Sibanda, T. and Caffarini, M. and Talapatra, A. and Santoleri, S. and Meregalli, M. and Bano-Otalora, B. and Bigot, A. and Bozzoni, I. and Bonini, C. and Mouly, V. and Torrente, Y. and Cossu, G.
EMBO Molecular Medicine 4 March 2024 (In Press)

2023

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma.
Finotto, L. and Cole, B. and Giese, W. and Baumann, E. and Claeys, A. and Vanmechelen, M. and Decraene, B. and Derweduwe, M. and Dubroja Lakic, N. and Shankar, G. and Nagathihalli Kantharaju, M. and Albrecht, J.P. and Geudens, I. and Stanchi, F. and Ligon, K.L. and Boeckx, B. and Lambrechts, D. and Harrington, K. and Van Den Bosch, L. and De Vleeschouwer, S. and De Smet, F. and Gerhardt, H.
EMBO Molecular Medicine 15 (11): e18144. 8 November 2023

Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
Zhang, L. and Wirth, M. and Patra, U. and Stroh, J. and Isaakidis, K. and Rieger, L. and Kossatz, S. and Milanovic, M. and Zang, C. and Demel, U. and Keiten-Schmitz, J. and Wagner, K. and Steiger, K. and Rad, R. and Bassermann, F. and Müller, S. and Keller, U. and Schick, M.
EMBO Molecular Medicine 15 (9): e16431. September 2023

Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy.
Kalkan, H. and Pagano, E. and Paris, D. and Panza, E. and Cuozzo, M. and Moriello, C. and Piscitelli, F. and Abolghasemi, A. and Gazzerro, E. and Silvestri, C. and Capasso, R. and Motta, A. and Russo, R. and Di Marzo, V. and Iannotti, F.A.
EMBO Molecular Medicine 15 (3): e16225. 8 March 2023

2022

Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M. and Wang, Y.H. and Kaufmann, U. and Gerbeth, L. and Sand, A. and Brunkhorst, M. and Weidner, P. and Ziegler, J.F. and Böttcher, C. and Schlickeiser, S. and Fernández, C. and Yamashita, M. and Stauderman, K. and Sun, K. and Kunkel, D. and Prakriya, M. and Sanders, A.D. and Siegmund, B. and Feske, S. and Weidinger, C.
EMBO Molecular Medicine : e15687. 2 August 2022

2021

Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.
Uhlitz, F. and Bischoff, P. and Peidli, S. and Sieber, A. and Trinks, A. and Lüthen, M. and Obermayer, B. and Blanc, E. and Ruchiy, Y. and Sell, T. and Mamlouk, S. and Arsie, R. and Wei, T.T. and Klotz-Noack, K. and Schwarz, R.F. and Sawitzki, B. and Kamphues, C. and Beule, D. and Landthaler, M. and Sers, C. and Horst, D. and Blüthgen, N. and Morkel, M.
EMBO Molecular Medicine 13 (10): e14123. 7 October 2021

Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy.
Sommariva, E. and Stadiotti, I. and Casella, M. and Catto, V. and Dello Russo, A. and Carbucicchio, C. and Arnaboldi, L. and De Metrio, S. and Milano, G. and Scopece, A. and Casaburo, M. and Andreini, D. and Mushtaq, S. and Conte, E. and Chiesa, M. and Birchmeier, W. and Cogliati, E. and Paolin, A. and König, E. and Meraviglia, V. and De Musso, M. and Volani, C. and Cattelan, G. and Rauhe, W. and Turnu, L. and Porro, B. and Pedrazzini, M. and Camera, M. and Corsini, A. and Tondo, C. and Rossini, A. and Pompilio, G.
EMBO Molecular Medicine 13 (9): e14365. 7 September 2021

Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19.
Theobald, S.J. and Simonis, A. and Georgomanolis, T. and Kreer, C. and Zehner, M. and Eisfeld, H.S. and Albert, M.C. and Chhen, J. and Motameny, S. and Erger, F. and Fischer, J. and Malin, J.J. and Gräb, J. and Winter, S. and Pouikli, A. and David, F. and Böll, B. and Koehler, P. and Vanshylla, K. and Gruell, H. and Suárez, I. and Hallek, M. and Fätkenheuer, G. and Jung, N. and Cornely, O.A. and Lehmann, C. and Tessarz, P. and Altmüller, J. and Nürnberg, P. and Kashkar, H. and Klein, F. and Koch, M. and Rybniker, J.
EMBO Molecular Medicine 13 (8): e14150. 9 August 2021

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation.
Cuello, F. and Knaust, A.E. and Saleem, U. and Loos, M. and Raabe, J. and Mosqueira, D. and Laufer, S. and Schweizer, M. and Kraak, P. and Flenner, F. and Ulmer, B.M and Braren, I. and Yin, X. and Theofilatos, K. and Ruiz-Orera, J. and Patone, G. and Klampe, B. and Schulze, T. and Piasecki, A. and Pinto, Y. and Vink, A. and Hübner, N. and Harding, S. and Mayr, M. and Denning, C. and Eschenhagen, T. and Hansen, A.
EMBO Molecular Medicine 13 (6): e13074. 7 June 2021

Epithelial response to IFN-γ promotes SARS-CoV-2 infection.
Heuberger, J. and Trimpert, J. and Vladimirova, D. and Goosmann, C. and Lin, M. and Schmuck, R. and Mollenkopf, H.J. and Brinkmann, V. and Tacke, F. and Osterrieder, N. and Sigal, M.
EMBO Molecular Medicine 13 (4): e13191. 9 April 2021

2020

Sarcoma treatment in the era of molecular medicine.
Grünewald, T.G.P. and Alonso, M. and Avnet, S. and Banito, A. and Burdach, S. and Cidre-Aranaz, F. and Di Pompo, G. and Distel, M. and Dorado-Garcia, H. and Garcia-Castro, J. and González-González, L. and Grigoriadis, A.E. and Kasan, M. and Koelsche, C. and Krumbholz, M. and Lecanda, F. and Lemma, S. and Longo, D.L. and Madrigal-Esquivel, C. and Morales-Molina, Á. and Musa, J. and Ohmura, S. and Ory, B. and Pereira-Silva, M. and Perut, F. and Rodriguez, R. and Seeling, C. and Al Shaaili, N. and Shaabani, S. and Shiavone, K. and Sinha, S. and Tomazou, E.M. and Trautmann, M. and Vela, M. and Versleijen-Jonkers, Y.M.H. and Visgauss, J. and Zalacain, M. and Schober, S.J. and Lissat, A. and English, W.R. and Baldini, Ni. and Heymann, D.
EMBO Molecular Medicine 12 : e11131. 6 November 2020

Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity.
Koch, C. and Kuske, A. and Joosse, S.A. and Yigit, G. and Sflomos, G. and Thaler, S. and Smit, D.J. and Werner, S. and Borgmann, K. and Gärtner, S. and Mossahebi Mohammadi, P. and Battista, L. and Cayrefourcq, L. and Altmüller, J. and Salinas-Riester, G. and Raithatha, K. and Zibat, A. and Goy, Y. and Ott, L. and Bartkowiak, K. and Tan, T.Z. and Zhou, Q. and Speicher, M.R. and Müller, V. and Gorges, T.M. and Jücker, M. and Thiery, J.P. and Brisken, C. and Riethdorf, S. and Alix-Panabières, C. and Pantel, K.
EMBO Molecular Medicine 12 (9): e11908. 7 September 2020

"Designer cytokines" targeting the tumor vasculature - think global and act local.
Kammertoens, T. and Kemna, J. and Leisegang, M.
EMBO Molecular Medicine 12 (2): e11801. 7 February 2020

2019

TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.
Grund, A. and Szaroszyk, M. and Korf-Klingebiel, M. and Malek Mohammadi, M. and Trogisch, F.A. and Schrameck, U. and Gigina, A. and Tiedje, C. and Gaestel, M. and Kraft, T. and Hegermann, J. and Batkai, S. and Thum, T. and Perrot, A. and Remedios, C.D. and Riechert, E. and Völkers, M. and Doroudgar, S. and Jungmann, A. and Bauer, R. and Yin, X. and Mayr, M. and Wollert, K.C. and Pich, A. and Xiao, H. and Katus, H.A. and Bauersachs, J. and Müller, O.J. and Heineke, J.
EMBO Molecular Medicine 11 (10): e10018. 1 October 2019

2018

Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations.
Otten, C. and Knox, J. and Boulday, G. and Eymery, M. and Haniszewski, M. and Neuenschwander, M. and Radetzki, S. and Vogt, I. and Hähn, K. and De Luca, C. and Cardoso, C. and Hamad, S. and Igual Gil, C. and Roy, P. and Albiges‐Rizo, C. and Faurobert, E. and von Kries, J.P. and Campillos, M. and Tournier‐Lasserve, E. and Derry, W.B. and Abdelilah-Seyfried, S.
EMBO Molecular Medicine 10 (10): e9155. 1 October 2018

The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.
Althof, N. and Goetzke, C.C. and Kespohl, M. and Voss, K. and Heuser, A. and Pinkert, S. and Kaya, Z. and Klingel, K. and Beling, A.
EMBO Molecular Medicine 10 (2): 200-218. 1 February 2018

2017

Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
Mathivet, T. and Bouleti, C. and Van Woensel, M. and Stanchi, F. and Verschuere, T. and Phng, L.K. and Dejaegher, J. and Balcer, M. and Matsumoto, K. and Georgieva, P.B. and Belmans, J. and Sciot, R. and Stockmann, C. and Mazzone, M. and De Vleeschouwer, S. and Gerhardt, H.
EMBO Molecular Medicine 9 (12): 1629-1645. 1 December 2017

2016

The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment.
Schloss, M.J. and Horckmans, M. and Nitz, K. and Duchene, J. and Drechsler, M. and Bidzhekov, K. and Scheiermann, C. and Weber, C. and Soehnlein, O. and Steffens, S.
EMBO Molecular Medicine 8 (8): 937-948. 1 August 2016

2015

Mutant Cullin causes cardiovascular compromise.
Luft, F.C.
EMBO Molecular Medicine 7 (10): 1254-1256. 1 October 2015

Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?
Ebert, A.D. and Diecke, S. and Chen, I.Y. and Wu, J.C.
EMBO Molecular Medicine 7 (9): 1090-1103. 16 July 2015

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma.
Philipp-Abbrederis, K. and Herrmann, K. and Knop, S. and Schottelius, M. and Eiber, M. and Lückerath, K. and Pietschmann, E. and Habringer, S. and Gerngroß, C. and Franke, K. and Rudelius, M. and Schirbel, A. and Lapa, C. and Schwamborn, K. and Steidle, S. and Hartmann, E. and Rosenwald, A. and Kropf, S. and Beer, A.J. and Peschel, C. and Einsele, H. and Buck, An.K. and Schwaiger, M. and Götze, K. and Wester, H.J. and Keller, U.
EMBO Molecular Medicine 7 (4): 477-487. 1 April 2015

Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy.
Gramlich, M. and Pane, L.S. and Zhou, Q. and Chen, Z. and Murgia, M. and Schoetterl, S. and Goedel, A. and Metzger, K. and Brade, T. and Parrotta, E. and Schaller, M. and Gerull, B. and Thierfelder, L. and Aartsma-Rus, A. and Labeit, S. and Atherton, J.J. and McGaughran, J. and Harvey, R.P. and Sinnecker, D. and Mann, M. and Laugwitz, K.L. and Gawaz, M.P. and Moretti, A.
EMBO Molecular Medicine 7 (5): 562-576. 10 March 2015

2013

Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation.
Wang, Y. and Gogol-Döring, A. and Hu, H. and Fröhler, S. and Ma, Y. and Jens, M. and Maaskola, J. and Murakawa, Y. and Quedenau, C. and Landthaler, M. and Kalscheuer, V. and Wieczorek, D. and Wang, Y. and Hu, Y. and Chen, W.
EMBO Molecular Medicine 5 (9): 1431-1442. September 2013

Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia.
Regalo, G. and Leutz, A.
EMBO Molecular Medicine 5 (8): 1154-1164. August 2013

2012

A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule.
Hennings, J.C. and Picard, N. and Huebner, A.K. and Stauber, T. and Maier, H. and Brown, D. and Jentsch, T.J. and Vargas-Poussou, R. and Eladari, D. and Huebner, C.A.
EMBO Molecular Medicine 4 (10): 1057-1071. October 2012

Krueppel-like factor 15 regulates Wnt/beta-catenin transcription and controls cardiac progenitor cell fate in the postnatal heart.
Noack, C. and Zafiriou, M.P. and Schaeffer, H.J. and Renger, A. and Pavlova, E. and Dietz, R. and Zimmermann, W.H. and Bergmann, M.W. and Zelarayan, L.C.
EMBO Molecular Medicine 4 (9): 992-1007. September 2012

Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers.
Kaden, D. and Harmeier, A. and Weise, C. and Munter, L.M. and Althoff, V. and Rost, B.R. and Hildebrand, P.W. and Schmitz, D. and Schaefer, M. and Lurz, R. and Skodda, S. and Yamamoto, R. and Arlt, S. and Finckh, U. and Multhaup, G.
EMBO Molecular Medicine 4 (7): 647-659. July 2012

This list was generated on Wed Apr 17 02:34:32 2024 CEST.
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