2024
CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.
Greensmith, R., Lape, I.T., Riella, C.V., Schubert, A.J., Metzger, J.J., Dighe, A.S., Tan, X., Hemmer, B., Rau, J., Wendlinger, S., Diederich, N., Schütz, A., Riella, L.V. and Kaminski, M.M.
EMBO Molecular Medicine
13 September 2024
(In Press)
Disrupting TSLP-TSLP receptor interactions via putative small molecule inhibitors yields a novel and efficient treatment option for atopic diseases.
Adhikary, P.P., Idowu, T., Tan, Z., Hoang, C., Shanta, S., Dumbani, M., Mappalakayil, L., Awasthi, B., Bermudez, M., Weiner, J., Beule, D., Wolber, G., Page, B.D. and Hedtrich, S.
EMBO Molecular Medicine 16
(7): 1630-1656.
15 July 2024
Cell-mediated exon skipping normalizes dystrophin expression and muscle function in a new mouse model of Duchenne Muscular Dystrophy.
Galli, F., Bragg, L., Rossi, M., Proietti, D., Perani, L., Bacigaluppi, M., Tonlorenzi, R., Sibanda, T., Caffarini, M., Talapatra, A., Santoleri, S., Meregalli, M., Bano-Otalora, B., Bigot, A., Bozzoni, I., Bonini, C., Mouly, V., Torrente, Y. and Cossu, G.
EMBO Molecular Medicine 16
(4): 927-944.
15 April 2024
2023
Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma.
Finotto, L., Cole, B., Giese, W., Baumann, E., Claeys, A., Vanmechelen, M., Decraene, B., Derweduwe, M., Dubroja Lakic, N., Shankar, G., Nagathihalli Kantharaju, M., Albrecht, J.P., Geudens, I., Stanchi, F., Ligon, K.L., Boeckx, B., Lambrechts, D., Harrington, K., Van Den Bosch, L., De Vleeschouwer, S., De Smet, F. and Gerhardt, H.
EMBO Molecular Medicine 15
(11): e18144.
8 November 2023
Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
Zhang, L., Wirth, M., Patra, U., Stroh, J., Isaakidis, K., Rieger, L., Kossatz, S., Milanovic, M., Zang, C., Demel, U., Keiten-Schmitz, J., Wagner, K., Steiger, K., Rad, R., Bassermann, F., Müller, S., Keller, U. and Schick, M.
EMBO Molecular Medicine 15
(9): e16431.
September 2023
Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy.
Kalkan, H., Pagano, E., Paris, D., Panza, E., Cuozzo, M., Moriello, C., Piscitelli, F., Abolghasemi, A., Gazzerro, E., Silvestri, C., Capasso, R., Motta, A., Russo, R., Di Marzo, V. and Iannotti, F.A.
EMBO Molecular Medicine 15
(3): e16225.
8 March 2023
2022
Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M., Wang, Y.H., Kaufmann, U., Gerbeth, L., Sand, A., Brunkhorst, M., Weidner, P., Ziegler, J.F., Böttcher, C., Schlickeiser, S., Fernández, C., Yamashita, M., Stauderman, K., Sun, K., Kunkel, D., Prakriya, M., Sanders, A.D., Siegmund, B., Feske, S. and Weidinger, C.
EMBO Molecular Medicine
: e15687.
2 August 2022
2021
Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.
Uhlitz, F., Bischoff, P., Peidli, S., Sieber, A., Trinks, A., Lüthen, M., Obermayer, B., Blanc, E., Ruchiy, Y., Sell, T., Mamlouk, S., Arsie, R., Wei, T.T., Klotz-Noack, K., Schwarz, R.F., Sawitzki, B., Kamphues, C., Beule, D., Landthaler, M., Sers, C., Horst, D., Blüthgen, N. and Morkel, M.
EMBO Molecular Medicine 13
(10): e14123.
7 October 2021
Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy.
Sommariva, E., Stadiotti, I., Casella, M., Catto, V., Dello Russo, A., Carbucicchio, C., Arnaboldi, L., De Metrio, S., Milano, G., Scopece, A., Casaburo, M., Andreini, D., Mushtaq, S., Conte, E., Chiesa, M., Birchmeier, W., Cogliati, E., Paolin, A., König, E., Meraviglia, V., De Musso, M., Volani, C., Cattelan, G., Rauhe, W., Turnu, L., Porro, B., Pedrazzini, M., Camera, M., Corsini, A., Tondo, C., Rossini, A. and Pompilio, G.
EMBO Molecular Medicine 13
(9): e14365.
7 September 2021
Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19.
Theobald, S.J., Simonis, A., Georgomanolis, T., Kreer, C., Zehner, M., Eisfeld, H.S., Albert, M.C., Chhen, J., Motameny, S., Erger, F., Fischer, J., Malin, J.J., Gräb, J., Winter, S., Pouikli, A., David, F., Böll, B., Koehler, P., Vanshylla, K., Gruell, H., Suárez, I., Hallek, M., Fätkenheuer, G., Jung, N., Cornely, O.A., Lehmann, C., Tessarz, P., Altmüller, J., Nürnberg, P., Kashkar, H., Klein, F., Koch, M. and Rybniker, J.
EMBO Molecular Medicine 13
(8): e14150.
9 August 2021
Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation.
Cuello, F., Knaust, A.E., Saleem, U., Loos, M., Raabe, J., Mosqueira, D., Laufer, S., Schweizer, M., Kraak, P., Flenner, F., Ulmer, B.M, Braren, I., Yin, X., Theofilatos, K., Ruiz-Orera, J., Patone, G., Klampe, B., Schulze, T., Piasecki, A., Pinto, Y., Vink, A., Hübner, N., Harding, S., Mayr, M., Denning, C., Eschenhagen, T. and Hansen, A.
EMBO Molecular Medicine 13
(6): e13074.
7 June 2021
Epithelial response to IFN-γ promotes SARS-CoV-2 infection.
Heuberger, J., Trimpert, J., Vladimirova, D., Goosmann, C., Lin, M., Schmuck, R., Mollenkopf, H.J., Brinkmann, V., Tacke, F., Osterrieder, N. and Sigal, M.
EMBO Molecular Medicine 13
(4): e13191.
9 April 2021
2020
Sarcoma treatment in the era of molecular medicine.
Grünewald, T.G.P., Alonso, M., Avnet, S., Banito, A., Burdach, S., Cidre-Aranaz, F., Di Pompo, G., Distel, M., Dorado-Garcia, H., Garcia-Castro, J., González-González, L., Grigoriadis, A.E., Kasan, M., Koelsche, C., Krumbholz, M., Lecanda, F., Lemma, S., Longo, D.L., Madrigal-Esquivel, C., Morales-Molina, Á., Musa, J., Ohmura, S., Ory, B., Pereira-Silva, M., Perut, F., Rodriguez, R., Seeling, C., Al Shaaili, N., Shaabani, S., Shiavone, K., Sinha, S., Tomazou, E.M., Trautmann, M., Vela, M., Versleijen-Jonkers, Y.M.H., Visgauss, J., Zalacain, M., Schober, S.J., Lissat, A., English, W.R., Baldini, Ni. and Heymann, D.
EMBO Molecular Medicine 12
: e11131.
6 November 2020
Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity.
Koch, C., Kuske, A., Joosse, S.A., Yigit, G., Sflomos, G., Thaler, S., Smit, D.J., Werner, S., Borgmann, K., Gärtner, S., Mossahebi Mohammadi, P., Battista, L., Cayrefourcq, L., Altmüller, J., Salinas-Riester, G., Raithatha, K., Zibat, A., Goy, Y., Ott, L., Bartkowiak, K., Tan, T.Z., Zhou, Q., Speicher, M.R., Müller, V., Gorges, T.M., Jücker, M., Thiery, J.P., Brisken, C., Riethdorf, S., Alix-Panabières, C. and Pantel, K.
EMBO Molecular Medicine 12
(9): e11908.
7 September 2020
"Designer cytokines" targeting the tumor vasculature - think global and act local.
Kammertoens, T., Kemna, J. and Leisegang, M.
EMBO Molecular Medicine 12
(2): e11801.
7 February 2020
2019
TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.
Grund, A., Szaroszyk, M., Korf-Klingebiel, M., Malek Mohammadi, M., Trogisch, F.A., Schrameck, U., Gigina, A., Tiedje, C., Gaestel, M., Kraft, T., Hegermann, J., Batkai, S., Thum, T., Perrot, A., Remedios, C.D., Riechert, E., Völkers, M., Doroudgar, S., Jungmann, A., Bauer, R., Yin, X., Mayr, M., Wollert, K.C., Pich, A., Xiao, H., Katus, H.A., Bauersachs, J., Müller, O.J. and Heineke, J.
EMBO Molecular Medicine 11
(10): e10018.
1 October 2019
2018
Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations.
Otten, C., Knox, J., Boulday, G., Eymery, M., Haniszewski, M., Neuenschwander, M., Radetzki, S., Vogt, I., Hähn, K., De Luca, C., Cardoso, C., Hamad, S., Igual Gil, C., Roy, P., Albiges‐Rizo, C., Faurobert, E., von Kries, J.P., Campillos, M., Tournier‐Lasserve, E., Derry, W.B. and Abdelilah-Seyfried, S.
EMBO Molecular Medicine 10
(10): e9155.
1 October 2018
The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.
Althof, N., Goetzke, C.C., Kespohl, M., Voss, K., Heuser, A., Pinkert, S., Kaya, Z., Klingel, K. and Beling, A.
EMBO Molecular Medicine 10
(2): 200-218.
1 February 2018
2017
Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
Mathivet, T., Bouleti, C., Van Woensel, M., Stanchi, F., Verschuere, T., Phng, L.K., Dejaegher, J., Balcer, M., Matsumoto, K., Georgieva, P.B., Belmans, J., Sciot, R., Stockmann, C., Mazzone, M., De Vleeschouwer, S. and Gerhardt, H.
EMBO Molecular Medicine 9
(12): 1629-1645.
1 December 2017
2016
The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment.
Schloss, M.J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O. and Steffens, S.
EMBO Molecular Medicine 8
(8): 937-948.
1 August 2016
2015
Mutant Cullin causes cardiovascular compromise.
Luft, F.C.
EMBO Molecular Medicine 7
(10): 1254-1256.
1 October 2015
Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?
Ebert, A.D., Diecke, S., Chen, I.Y. and Wu, J.C.
EMBO Molecular Medicine 7
(9): 1090-1103.
16 July 2015
In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma.
Philipp-Abbrederis, K., Herrmann, K., Knop, S., Schottelius, M., Eiber, M., Lückerath, K., Pietschmann, E., Habringer, S., Gerngroß, C., Franke, K., Rudelius, M., Schirbel, A., Lapa, C., Schwamborn, K., Steidle, S., Hartmann, E., Rosenwald, A., Kropf, S., Beer, A.J., Peschel, C., Einsele, H., Buck, An.K., Schwaiger, M., Götze, K., Wester, H.J. and Keller, U.
EMBO Molecular Medicine 7
(4): 477-487.
1 April 2015
Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy.
Gramlich, M., Pane, L.S., Zhou, Q., Chen, Z., Murgia, M., Schoetterl, S., Goedel, A., Metzger, K., Brade, T., Parrotta, E., Schaller, M., Gerull, B., Thierfelder, L., Aartsma-Rus, A., Labeit, S., Atherton, J.J., McGaughran, J., Harvey, R.P., Sinnecker, D., Mann, M., Laugwitz, K.L., Gawaz, M.P. and Moretti, A.
EMBO Molecular Medicine 7
(5): 562-576.
10 March 2015
2013
Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation.
Wang, Y., Gogol-Döring, A., Hu, H., Fröhler, S., Ma, Y., Jens, M., Maaskola, J., Murakawa, Y., Quedenau, C., Landthaler, M., Kalscheuer, V., Wieczorek, D., Wang, Y., Hu, Y. and Chen, W.
EMBO Molecular Medicine 5
(9): 1431-1442.
September 2013
Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia.
Regalo, G. and Leutz, A.
EMBO Molecular Medicine 5
(8): 1154-1164.
August 2013
2012
A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule.
Hennings, J.C., Picard, N., Huebner, A.K., Stauber, T., Maier, H., Brown, D., Jentsch, T.J., Vargas-Poussou, R., Eladari, D. and Huebner, C.A.
EMBO Molecular Medicine 4
(10): 1057-1071.
October 2012
Krueppel-like factor 15 regulates Wnt/beta-catenin transcription and controls cardiac progenitor cell fate in the postnatal heart.
Noack, C., Zafiriou, M.P., Schaeffer, H.J., Renger, A., Pavlova, E., Dietz, R., Zimmermann, W.H., Bergmann, M.W. and Zelarayan, L.C.
EMBO Molecular Medicine 4
(9): 992-1007.
September 2012
Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers.
Kaden, D., Harmeier, A., Weise, C., Munter, L.M., Althoff, V., Rost, B.R., Hildebrand, P.W., Schmitz, D., Schaefer, M., Lurz, R., Skodda, S., Yamamoto, R., Arlt, S., Finckh, U. and Multhaup, G.
EMBO Molecular Medicine 4
(7): 647-659.
July 2012
This list was generated on Wed Oct 9 06:41:55 2024 UTC.