Browse by Journal Title

2022

Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T., Lindemann, P., Welle, A., Trouillet, V., Heißler, S., Nazaré, M. and Selbach, M.
ChemMedChem 17 (19): e202200346. 6 October 2022

2019

Structure-based screening of tetrazolylhydrazide inhibitors versus KDM4 histone demethylases.
Malecki, P.H., Rueger, N., Roatsch, M., Krylova, O., Link, A., Jung, M., Heinemann, U. and Weiss, M.S.
ChemMedChem 14 (21): 1828-1839. 6 November 2019

Probing 2H-indazoles as template for SGK1, Tie2 and SRC kinase inhibitors.
Schoene, J., Gazzi, T., Lindemann, P., Christmann, M., Volkamer, A. and Nazaré, M.
ChemMedChem 14 (16): 1514-1527. 20 August 2019

2015

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S., Eckert, C., Arkona, C., Radetzki, S., Böhm, K., Heinemann, U., Wolber, G., von Kries, J.P., Birchmeier, W. and Rademann, J.
ChemMedChem 10 (5): 815-826. May 2015

2011

Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain.
Saupe, J., Roske, Y., Schillinger, C., Kamdem, N., Radetzki, S., Diehl, A., Oschkinat, H., Krause, G., Heinemann, U. and Rademann, J.
ChemMedChem 6 (8): 1411-1422. 1 August 2011