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Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T. and Lindemann, P. and Welle, A. and Trouillet, V. and Heißler, S. and Nazaré, M. and Selbach, M.
ChemMedChem 17 (19): e202200346. 6 October 2022


Structure-based screening of tetrazolylhydrazide inhibitors versus KDM4 histone demethylases.
Malecki, P.H. and Rueger, N. and Roatsch, M. and Krylova, O. and Link, A. and Jung, M. and Heinemann, U. and Weiss, M.S.
ChemMedChem 14 (21): 1828-1839. 6 November 2019

Probing 2H-indazoles as template for SGK1, Tie2 and SRC kinase inhibitors.
Schoene, J. and Gazzi, T. and Lindemann, P. and Christmann, M. and Volkamer, A. and Nazaré, M.
ChemMedChem 14 (16): 1514-1527. 20 August 2019


Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S. and Eckert, C. and Arkona, C. and Radetzki, S. and Böhm, K. and Heinemann, U. and Wolber, G. and von Kries, J.P. and Birchmeier, W. and Rademann, J.
ChemMedChem 10 (5): 815-826. May 2015


Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain.
Saupe, J. and Roske, Y. and Schillinger, C. and Kamdem, N. and Radetzki, S. and Diehl, A. and Oschkinat, H. and Krause, G. and Heinemann, U. and Rademann, J.
ChemMedChem 6 (8): 1411-1422. 1 August 2011

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