2026

Probing 3-amino-2H-azaindazoles as allosteric inhibitors of the protein tyrosine phosphatase SHP2.
Amoussa, Machoud, Efrém, Nina-Louisa, Li, Feng, Guo, Ziqiong, Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Frank, Katrin Jana, Pach, Szymon, Wolf, Clemens Alexander, Bo, Feng, Lesina, Marina, Kintzel, Mika, Alsalim, Rana, Zeitz, Victoria, Csorba, Noémi, Radetzki, Silke ORCID: https://orcid.org/0000-0003-2688-2868, Keserű, György M., Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, Algül, Hana, Wolber, Gerhard, Li, Jia and Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330
ChemMedChem 21 (11): e70341. 15 June 2026

2022

Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T. ORCID: https://orcid.org/0000-0002-7181-9369, Lindemann, P. ORCID: https://orcid.org/0000-0002-8224-3764, Welle, A., Trouillet, V., Heißler, S., Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
ChemMedChem 17 (19): e202200346. 6 October 2022

2019

Structure-based screening of tetrazolylhydrazide inhibitors versus KDM4 histone demethylases.
Malecki, P.H. ORCID: https://orcid.org/0000-0003-1499-8310, Rueger, N., Roatsch, M. ORCID: https://orcid.org/0000-0002-9274-1433, Krylova, O., Link, A. ORCID: https://orcid.org/0000-0003-1262-6636, Jung, M. ORCID: https://orcid.org/0000-0002-6361-7716, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Weiss, M.S. ORCID: https://orcid.org/0000-0002-2362-7047
ChemMedChem 14 (21): 1828-1839. 6 November 2019

Probing 2H-indazoles as template for SGK1, Tie2 and SRC kinase inhibitors.
Schoene, J., Gazzi, T., Lindemann, P. ORCID: https://orcid.org/0000-0002-8224-3764, Christmann, M., Volkamer, A. ORCID: https://orcid.org/0000-0002-3760-580X and Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330
ChemMedChem 14 (16): 1514-1527. 20 August 2019

2015

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S., Eckert, C., Arkona, C., Radetzki, S. ORCID: https://orcid.org/0000-0003-2688-2868, Böhm, K., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Wolber, G., von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Rademann, J. ORCID: https://orcid.org/0000-0001-6678-3165
ChemMedChem 10 (5): 815-826. May 2015

2011

Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain.
Saupe, J. ORCID: https://orcid.org/0000-0003-4110-9881, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Schillinger, C., Kamdem, N., Radetzki, S. ORCID: https://orcid.org/0000-0003-2688-2868, Diehl, A., Oschkinat, H., Krause, G., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Rademann, J. ORCID: https://orcid.org/0000-0001-6678-3165
ChemMedChem 6 (8): 1411-1422. 1 August 2011