2026

Clonal lineage tracing of innate immune cells in human cancer.
Liu, Vincent, Sandor, Katalin, Yan, Patrick K., Miao, Zhuang, Yin, Yajie, Stickels, Robert R., Chen, Andy Y., Hiam-Galvez, Kamir, Gutierrez, Jacob, Zhang, Wenxi, Sajjath, Sairaj M., Valbuena, Raeline, Wang, Steven, Daniel, Bence, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Howitt, Brooke E., Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807 and Satpathy, Ansuman T.
Cancer Cell 4 June 2026 (In Press)

2025

Subclonal immune evasion in non-small cell lung cancer.
Dijkstra, K.K., Vendramin, R., Karagianni, D., Witsen, M., Gálvez-Cancino, F., Hill, M.S., Foster, K.A., Barbè, V., Angelova, M., Hynds, R.E., Pearce, D.R., Martínez-Ruiz, C., Black, J.R.M., Huebner, A., Pich, O., Rowan, A., Augustine, M., Puttick, C., Moore, D.A., Liu, L.L., Saghafinia, S., van de Haar, J., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Bola, S.K., Hiley, C.T., Jamal-Hanjani, M., McGranahan, N., Litchfield, K., Reading, J.L., Chain, B., Quezada, S.A., Voest, E.E. and Swanton, C.
Cancer Cell 43 (10): 1833-1849. 13 October 2025

2023

An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
Griger, J., Widholz, S.A., Jesinghaus, M., de Andrade Krätzig, N., Lange, S., Engleitner, T., Montero, J.J., Zhigalova, E., Öllinger, R., Suresh, V., Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Lier, S., Baranov, O., Trozzo, R., Ben Khaled, N., Chakraborty, S., Yu, J., Konukiewitz, B., Steiger, K., Pfarr, N., Rajput, A., Sailer, D., Keller, G., Schirmacher, P., Röcken, C., Fagerstedt, K.W., Mayerle, J., Schmidt-Supprian, M., Schneider, G., Weichert, W., Calado, D.P. ORCID: https://orcid.org/0000-0001-8239-7184, Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Klöppel, G., Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Saur, D. and Rad, R.
Cancer Cell 41 (7): 1327-1344.e10. 10 July 2023

2022

Dissecting the intracellular pancreatic tumor microbiome at single-cell level.
Schmidt, T.S.B. and Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X
Cancer Cell 40 (10): 1083-1085. 10 October 2022

Cellular hierarchies predict drug response in acute myeloid leukemia.
Raffel, S., Velten, L. and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Cancer Cell 40 (9): 917-919. 12 September 2022

2021

Humoral and cellular immune responses in SARS-CoV-2 mRNA-vaccinated patients with cancer.
Mairhofer, M., Kausche, L., Kaltenbrunner, S., Ghanem, R., Stegemann, M., Klein, K., Pammer, M., Rauscher, I., Salzer, H.J.F., Doppler, S., Habringer, A., Paar, C., Kimeswenger, S., Hoetzenecker, W., Lamprecht, B., Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Cell 39 (9): 1171-1172. 13 September 2021

2019

Age-related gliosis promotes central nervous system lymphoma through CCL19-mediated tumor cell retention.
O'Connor, T., Zhou, X., Kosla, J., Adili, A., Garcia Beccaria, M., Kotsiliti, E., Pfister, D., Johlke, A.L., Sinha, A., Sankowski, R., Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Lewis, R., Dokalis, N., Seubert, B., Höchst, B., Inverso, D., Heide, D., Zhang, W., Weihrich, P., Manske, K., Wohlleber, D., Anton, M., Hoellein, A., Seleznik, G., Bremer, J., Bleul, S., Augustin, H.G., Scherer, F., Koedel, U., Weber, A., Protzer, U., Förster, R., Wirth, T., Aguzzi, A., Meissner, F., Prinz, M., Baumann, B., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Knolle, P.A., von Baumgarten, L., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Heikenwalder, M.
Cancer Cell 36 (3): 250-267. 16 September 2019

2018

Proteomics, post-translational modifications, and integrative analyses reveal molecular heterogeneity within medulloblastoma subgroups.
Archer, T.C., Ehrenberger, T., Mundt, F., Gold, M.P., Krug, K., Mah, C.K., Mahoney, E.L., Daniel, C.J., LeNail, A., Ramamoorthy, D., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Mani, D.R., Zhang, H., Gillette, M.A., Clauser, K., Noble, M., Tang, L.C., Pierre-François, J., Silterra, J., Jensen, J., Tamayo, P., Korshunov, A., Pfister, S.M., Kool, M., Northcott, P.A., Sears, R.C., Lipton, J.O., Carr, S.A., Mesirov, J.P., Pomeroy, S.L. and Fraenkel, E.
Cancer Cell 34 (3): 396-410. 10 September 2018

UnSASPing senescence: unmasking tumor suppression?
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Cell 34 (1): 6-8. 9 July 2018

Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma.
Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Schleich, K., Yue, B., Ji, S., Lohneis, P., Kemper, K., Silvis, M.S., Qutob, N., van Rooijen, E., Werner-Klein, M., Li, L., Dhawan, D., Meierjohann, S., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Elkahloun, A., Treitschke, S., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Speck, C., Mallette, F.A., Zon, L.I., Holmen, S.L., Peeper, D.S., Samuels, Y., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931
Cancer Cell 33 (2): 322-336. 12 February 2018

2017

A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y., Malehmir, M., Healy, M.E., Bettermann, K., Lorentzen, A., Vucur, M., Ahuja, A.K., Böhm, F., Mertens, J.C., Shimizu, Y., Frick, L., Remouchamps, C., Mutreja, K., Kähne, T., Sundaravinayagam, D. ORCID: https://orcid.org/0000-0003-0717-7530, Wolf, M.J., Rehrauer, H., Koppe, C., Speicher, T., Padrissa-Altés, S., Maire, R., Schattenberg, J.M., Jeong, J.S., Liu, Lei, Zwirner, S., Boger, R., Hüser, N., Davis, R.J., Müllhaupt, B., Moch, H., Schulze-Bergkamen, H., Clavien, P.A., Werner, S., Borsig, L., Luther, S.A., Jost, P.J., Weinlich, R., Unger, K., Behrens, A., Hillert, L., Dillon, C., Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793, Wallach, D., Dejardin, E., Zender, L., Naumann, M., Walczak, H., Green, D.R., Lopes, M., Lavrik, I., Luedde, T., Heikenwalder, M. and Weber, A.
Cancer Cell 32 (3): 342-359. 11 September 2017

2016

SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin.
Ferone, G., Song, J.Y., Sutherland, K.D., Bhaskaran, R., Monkhorst, K., Lambooij, J.P., Proost, N., Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251 and Berns, A.
Cancer Cell 30 (4): 519-532. 10 October 2016

Structural decoding of the netrin-1/UNC5 interaction and its therapeutical implications in cancers.
Grandin, M., Meier, M., Delcros, J.G., Nikodemus, D., Reuten, R., Patel, T.R., Goldschneider, D., Orriss, G., Krahn, N., Boussouar, A., Abes, R., Dean, Y., Neves, D., Bernet, A., Depil, S., Schneiders, F., Poole, K. ORCID: https://orcid.org/0000-0003-0879-6093, Dante, R., Koch, M., Mehlen, P. and Stetefeld, J.
Cancer Cell 29 (2): 173-185. 8 February 2016

Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epithelial-mesenchymal transition in non-small-cell lung cancer.
Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658, Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251, Proost, N., Siteur, B., Cesaroni, M., Koppens, M., Xie, H., Sutherland, K.D., Hulsman, D., Citterio, E., Orkin, S., Berns, A. and van Lohuizen, M.
Cancer Cell 29 (1): 17-31. 11 January 2016

2015

A MYC-driven change in mitochondrial dynamics limits YAP/TAZ function in mammary epithelial cells and breast cancer.
von Eyss, B. ORCID: https://orcid.org/0000-0002-4731-6841, Jaenicke, L.A., Kortlever, R.M., Royla, N., Wiese, K.E., Letschert, S., McDuffus, L.A., Sauer, M., Rosenwald, A., Evan, G.I., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Eilers, M.
Cancer Cell 28 (6): 743-757. 14 December 2015

2014

Tumor vessel normalization by chloroquine independent of autophagy.
Maes, H., Kuchnio, A., Peric, A., Moens, S., Nys, K., De Bock, K., Quaegebeur, A., Schoors, S., Georgiadou, M., Wouters, J., Vinckier, S., Vankelecom, H., Garmyn, M., Vion, A.C., Radtke, F., Boulanger, C., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Dejana, E., Dewerchin, M., Ghesquière, B., Annaert, W., Agostinis, P. and Carmeliet, P.
Cancer Cell 26 (2): 190-206. 11 August 2014

2013

Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.
Brockmann, M., Poon, E., Berry, T., Carstensen, A., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Rycak, L., Jamin, Y., Thway, K., Robinson, S.P., Roels, F., Witt, O., Fischer, M., Chesler, L. and Eilers, M.
Cancer Cell 24 (1): 75-89. 8 July 2013

In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.
Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251, Cesaroni, M., Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658, de Vries, N., Hulsman, D., Bruggeman, S.W., Lancini, C. and van Lohuizen, M.
Cancer Cell 23 (5): 660-676. 13 May 2013

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.
Bono, F., De Smet, F., Herbert, C., De Bock, K., Georgiadou, M., Fons, P., Tjwa, M., Alcouffe, C., Ny, A., Bianciotto, M., Jonckx, B., Murakami, M., Lanahan, A.A., Michielsen, C., Sibrac, D., Dol-Gleizes, F., Mazzone, M., Zacchigna, S., Herault, J.P., Fischer, C., Rigon, P., Ruiz de Almodovar, C., Claes, F., Blanc, I., Poesen, K., Zhang, J., Segura, I., Gueguen, G., Bordes, M.F., Lambrechts, D., Broussy, R., van de Wouwer, M., Michaux, C., Shimada, T., Jean, I., Blacher, S., Noel, A., Motte, P., Rom, E., Rakic, J.M., Katsuma, S., Schaeffer, P., Yayon, A., Van Schepdael, A., Schwalbe, H., Gervasio, F.L., Carmeliet, G., Rozensky, J., Dewerchin, M., Simons, M., Christopoulos, A., Herbert, J.M. and Carmeliet, P.
Cancer Cell 23 (4): 477-488. 15 April 2013

It's the peptide-MHC affinity, stupid.
Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141 and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Cancer Cell 23 (4): 429-431. 15 April 2013

2012

Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma.
Kopp, J.L., von Figura, G., Mayes, E., Liu, F.F., Dubois, C.L., Morris, J.P., Pan, F.C., Akiyama, H., Wright, C.V.E., Jensen, K., Hebrok, M. and Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785
Cancer Cell 22 (6): 737-50. 11 December 2012

Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Nagel, D., Spranger, S., Vincendeau, M., Grau, M., Raffegerst, S., Kloo, B., Hlahla, D., Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Hadian, K., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Lenz, P., Lenz, G., Schendel, D.J. and Krappmann, D. ORCID: https://orcid.org/0000-0001-7640-3234
Cancer Cell 22 (6): 825-837. 11 December 2012

Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.
Sander, S. ORCID: https://orcid.org/0000-0003-4645-3366, Calado, D.P. ORCID: https://orcid.org/0000-0001-8239-7184, Srinivasan, L., Köchert, K. ORCID: https://orcid.org/0000-0002-5548-2022, Zhang, B., Rosolowski, M., Rodig, S.J., Holzmann, K., Stilgenbauer, S., Siebert, R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Cancer Cell 22 (2): 167-179. 14 August 2012

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Bywater, M.J., Poortinga, G., Sanij, E., Hein, N., Peck, A., Cullinane, C., Wall, M., Cluse, L., Drygin, D., Anderes, K., Huser, N., Proffitt, C., Bliesath, J., Haddach, M., Schwaebe, M.K., Ryckman, D.M., Rice, W.G., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Lowe, S.W., Johnstone, R.W., Pearson, R.B., McArthur, G.A. and Hannan, R.D.
Cancer Cell 22 (1): 51-65. 10 July 2012

2011

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K. ORCID: https://orcid.org/0000-0002-0429-200X, Buschow, C., Herrmann, A., Milojkovic, A., Loddenkemper, C., Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141, Daniel, P., Yu, H., Charo, J. ORCID: https://orcid.org/0000-0002-5409-9160 and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Cancer Cell 20 (6): 755-767. 13 December 2011

2010

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma.
Calado, D.P. ORCID: https://orcid.org/0000-0001-8239-7184, Zhang, B., Srinivasan, L., Sasaki, Y., Seagal, J., Unitt, C., Rodig, S., Kutok, J., Tarakhovsky, A., Schmidt-Supprian, M. and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Cancer Cell 18 (6): 580-589. 14 December 2010

Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Loddenkemper, C., Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Tabor, V., Aichele, P., Stein, H., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Jenuwein, T. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Cell 17 (3): 262-272. 16 March 2010

2002

Fas ligand breaks tolerance to self-antigens and induces tumor immunity mediated by antibodies.
Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Gallimore, A., Jones, E., Sawitzki, B., Cerundolo, V. and Screaton, G.R.
Cancer Cell 2 (4): 315-22. October 2002

Dissecting p53 tumor suppressor functions in vivo.
Schmitt, C.A., Fridman, J.S., Yang, M., Baranov, E., Hoffman, R.M. and Lowe, S.W.
Cancer Cell 1 (3): 289-298. 1 April 2002