Browse by Journal Title

2023

AML with complex karyotype: extreme genomic complexity revealed by combined long-read sequencing and Hi-C technology.
Klever, M.K. and Sträng, E. and Hetzel, S. and Jungnitsch, J. and Dolnik, A. and Schöpflin, R. and Schrezenmeier, J.F.F. and Schick, F. and Blau, O. and Westermann, J. and Rücker, F.G. and Xia, Z. and Döhner, K. and Schrezenmeier, H. and Spielmann, M. and Meissner, A. and Melo, U.S. and Mundlos, S. and Bullinger, L.
Blood Advances 7 (21): 6520-6531. 14 November 2023

Retained functional normal and preleukemic HSCs at diagnosis are associated to good prognosis in DNMT3Amut NPM1mut AMLs.
Donato, E. and Correia, N.C. and Andresen, C. and Karpova, D. and Würth, R. and Klein, C. and Sohn, M. and Przybylla, A. and Zeisberger, P. and Rothfelder, K. and Salih, H.R. and Bonig, H. and Stasik, S. and Röllig, C. and Dolnik, A. and Bullinger, L. and Buchholz, F. and Thiede, C.D. and Hübschmann, D. and Trumpp, A.
Blood Advances 7 (6): 1011-1018. 28 March 2023

SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Heynen, G.J.J.E. and Baumgartner, F. and Heider, M. and Patra, U. and Holz, M. and Braune, J. and Kaiser, M. and Schäffer, I. and Bamopoulos, S.A. and Ramberger, E. and Murgai, A. and Ng, Y.L.D. and Demel, U.M. and Laue, D. and Liebig, S. and Krüger, J. and Janz, M. and Nogai, A. and Schick, M. and Mertins, P. and Müller, S. and Bassermann, F. and Krönke, J. and Keller, U. and Wirth, M.
Blood Advances 7 (4): 469-481. 28 February 2023

Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis.
Kurtova, A.V. and Heinlein, M. and Haas, S. and Velten, L. and Dijkgraaf, G.J.P. and Storm, E.E. and Kljavin, N.M. and Boumahdi, S. and Himmels, P. and Herault, A. and Mancini, A.G. and Koeppen, H. and Dail, M. and Yan, M. and Zhang, J. and Koch, U. and Radtke, F. and Modrusan, Z. and Metcalfe, C. and Piskol, R. and de Sauvage, F.J.
Blood Advances 7 (4): 491-507. 28 February 2023

2022

Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications.
Döhner, H. and Weber, D. and Krzykalla, J. and Fiedler, W. and Wulf, G.G. and Salih, H.R. and Lübbert, M. and Kühn, M. and Schroeder, T. and Salwender, H. and Götze, K.S. and Westermann, J. and Fransecky, L. and Mayer, K. and Hertenstein, B. and Ringhoffer, M. and Tischler, H.J. and Machherndl-Spandl, S. and Schrade, A. and Paschka, P. and Gaidzik, V.I. and Theis, F. and Thol, F.R. and Heuser, M. and Schlenk, R.F. and Bullinger, L. and Saadati, M. and Benner, A. and Larson, R.A. and Stone, R.M. and Döhner, K. and Ganser, A.
Blood Advances 6 (18): 5345-5355. 27 September 2022

A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo.
Demel, U.M. and Lutz, R. and Sujer, S. and Demerdash, Y. and Sood, S. and Grünschläger, F. and Kuck, A. and Werner, P. and Blaszkiewicz, S. and Uckelmann, H.J. and Haas, S. and Essers, M.
Blood Advances 6 (11): 3513-3528. 10 June 2022

MCT1 is a predictive marker for lenalidomide maintenance therapy in multiple myeloma.
Stroh, J. and Seckinger, A. and Heider, M. and Rudelius, M. and Eichner, R. and Schick, M. and Slawska, J. and Emde, M. and Salwender, H. and Bertsch, U. and Goldschmidt, H. and Weisel, K.C. and Scheid, C. and Keller, U. and Hose, D. and Bassermann, F.
Blood Advances 6 (2): 515-520. 25 January 2022

2021

Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas.
Liebers, N. and Duell, J. and Fitzgerald, D. and Kerkhoff, A. and Noerenberg, D. and Kaebisch, E. and Acker, F. and Fuhrmann, S. and Leng, C. and Welslau, M. and Chemnitz, J. and Middeke, J.M. and Weber, T. and Holtick, U. and Trappe, R. and Pfannes, R. and Liersch, R. and Spoer, C. and Fuxius, S. and Gebauer, N. and Caillé, L. and Geer, T. and Koenecke, C. and Keller, U. and Claus, R. and Mougiakakos, D. and Mayer, S. and Huettmann, A. and Pott, C. and Trummer, A. and Wulf, G. and Brunnberg, U. and Bullinger, L. and Hess, G. and Mueller-Tidow, C. and Glass, B. and Lenz, G. and Dreger, P. and Dietrich, S.
Blood Advances 5 (13): 2707-2716. 13 July 2021

Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma.
Bohl, S.R. and Schmalbrock, L.K. and Bauhuf, I. and Meyer, T. and Dolnik, A. and Szyska, M. and Blätte, T.J. and Knödler, S. and Röhner, L. and Miller, D. and Kull, M. and Langer, C. and Döhner, H. and Letai, A. and Damm, F. and Heckl, D. and Bullinger, L. and Krönke, J.
Blood Advances 5 (9): 2391-2402. 11 May 2021

Posttransplantation MRD monitoring in patients with AML by next-generation sequencing using DTA and non-DTA mutations.
Heuser, M. and Heida, B. and Büttner, K. and Wienecke, C.P. and Teich, K. and Funke, C. and Brandes, M. and Klement, P. and Liebich, A. and Wichmann, M. and Neziri, B. and Chaturvedi, A. and Kloos, A. and Mintzas, K. and Gaidzik, V.I. and Paschka, P. and Bullinger, L. and Fiedler, W. and Heim, A. and Puppe, W. and Krauter, J. and Döhner, K. and Döhner, H. and Ganser, A. and Stadler, M. and Hambach, L. and Gabdoulline, R. and Thol, F.
Blood Advances 5 (9): 2294-2304. 11 May 2021

Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice.
Li, C. and Goncalves, K.A. and Raskó, T. and Pande, A. and Gil, S. and Liu, Z. and Izsvák, Z. and Papayannopoulou, T. and Davis, J.C. and Kiem, H.P. and Lieber, A.
Blood Advances 5 (5): 1239-1249. 9 March 2021

Deregulated expression of circular RNAs in acute myeloid leukemia.
Lux, S. and Blätte, T.J. and Gillissen, B. and Richter, A. and Cocciardi, S. and Skambraks, S. and Schwarz, K. and Schrezenmeier, H. and Döhner, H. and Döhner, K. and Dolnik, A. and Bullinger, L.
Blood Advances 5 (5): 1490-1503. 9 March 2021

2020

Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.
Jahn, N. and Terzer, T. and Sträng, E. and Dolnik, A. and Cocciardi, S. and Panina, E. and Corbacioglu, A. and Herzig, J. and Weber, D. and Schrade, A. and Götze, K. and Schröder, T. and Lübbert, M. and Wellnitz, D. and Koller, E. and Schlenk, R.F. and Gaidzik, V.I. and Paschka, P. and Rücker, F.G. and Heuser, M. and Thol, F. and Ganser, A. and Benner, A. and Döhner, H. and Bullinger, L. and Döhner, K.
Blood Advances 4 (24): 6342-6352. 22 December 2020

ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP.
Völker, L.A. and Kaufeld, J. and Miesbach, W. and Brähler, S. and Reinhardt, M. and Kühne, L. and Mühlfeld, A. and Schreiber, A. and Gaedeke, J. and Tölle, M. and Jabs, W.J. and Özcan, F. and Markau, S. and Girndt, M. and Bauer, F. and Westhoff, T.H. and Felten, H. and Hausberg, M. and Brand, M. and Gerth, J. and Bieringer, M. and Bommer, M. and Zschiedrich, S. and Schneider, J. and Elitok, S. and Gawlik, A. and Gäckler, A. and Kribben, A. and Schwenger, V. and Schoenermarck, U. and Roeder, M. and Radermacher, J. and Bramstedt, J. and Morgner, A. and Herbst, R. and Harth, A. and Potthoff, S.A. and von Auer, C. and Wendt, R. and Christ, H. and Brinkkoetter, P.T. and Menne, J.
Blood Advances 4 (13): 3093-3101. 14 July 2020

Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura.
Völker, L.A. and Kaufeld, J. and Miesbach, W. and Brähler, S. and Reinhardt, M. and Kühne, L. and Mühlfeld, A. and Schreiber, A. and Gaedeke, J. and Tölle, M. and Jabs, W.J. and Özcan, F. and Markau, S. and Girndt, M.. and Bauer, F. and Westhoff, T.H. and Felten, H. and Hausberg, M. and Brand, M. and Gerth, J. and Bieringer, M. and Bommer, M. and Zschiedrich, S. and Schneider, J. and Elitok, S. and Gawlik, A. and Gäckler, A. and Kribben, A. and Schwenger, V. and Schoenermarck, U. and Roeder, M. and Radermacher, J. and Bramstedt, J. and Morgner, A. and Herbst, R. and Harth, A. and Potthoff, S.A. and von Auer, C. and Wendt, R. and Christ, H. and Brinkkoetter, P.T. and Menne, J.
Blood Advances 4 (13): 3085-3092. 14 July 2020

2019

Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking.
Lareau, C.A. and Ludwig, L.S. and Sankaran, V.G.
Blood Advances 3 (24): 4161-4165. 23 December 2019

Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response.
Nasri, M. and Mir, P. and Dannenmann, B. and Amend, D. and Skroblyn, T. and Xu, Y. and Schulze-Osthoff, K. and Klimiankou, M. and Welte, K. and Skokowa, J.
Blood Advances 3 (1): 63-71. 8 January 2019