Browse by Research Team

2015

Cross-recognition of a myelin peptide by CD8(+) T cells in the CNS is not sufficient to promote neuronal damage.
Reuter, E. and Gollan, R. and Grohmann, N. and Paterka, M. and Salmon, H. and Birkenstock, J. and Richers, S. and Leuenberger, T. and Brandt, A.U. and Kuhlmann, T. and Zipp, F. and Siffrin, V.
Journal of Neuroscience 35 (12): 4837-4850. 25 March 2015

2014

Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase.
Leuenberger, T. and Pfueller, C.F. and Luessi, F. and Bendix, I. and Paterka, M. and Prozorovski, T. and Treue, D. and Luenstedt, S. and Herz, J. and Siffrin, V. and Infante-Duarte, C. and Zipp, F. and Waiczies, S.
PLoS ONE 9 (7): e100871. 11 July 2014

2013

The role of CD8(+) T cells and their local interaction with CD4(+) T cells in myelin oligodendrocyte glycoprotein(35-55)-induced experimental autoimmune encephalomyelitis.
Leuenberger, T. and Paterka, M. and Reuter, E. and Herz, J. and Niesner, R.A. and Radbruch, H. and Bopp, T. and Zipp, F. and Siffrin, V.
Journal of Immunology 191 (10): 4960-4968. 15 November 2013

A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis.
Mechelli, R. and Umeton, R. and Policano, C. and Annibali, V. and Coarelli, G. and Ricigliano, V.A.G. and Vittori, D. and Fornasiero, A. and Buscarinu, M.C. and Romano, S. and Salvetti, M. and Ristori, G.
PLoS ONE 8 (5): e63300. 16 May 2013

Parallelized TCSPC for dynamic intravital fluorescence lifetime imaging: quantifying neuronal dysfunction in neuroinflammation.
Rinnenthal, J.L. and Börnchen, C. and Radbruch, H. and Andresen, V. and Mossakowski, A. and Siffrin, V. and Seelemann, T. and Spiecker, H. and Moll, I. and Herz, J. and Hauser, A.E. and Zipp, F. and Behne, M.J. and Niesner, R.
PLoS ONE 8 (4): e60100. 16 April 2013

2011

In vivo imaging of lymphocytes in the CNS reveals different behaviour of naive T cells in health and autoimmunity.
Herz, J. and Paterka, M. and Niesner, R.A. and Brandt, A.U. and Siffrin, V. and Leuenberger, T. and Birkenstock, J. and Mossakowski, A. and Glumm, R. and Zipp, F. and Radbruch, H.
Journal of Neuroinflammation 8 (1): 131. 6 October 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Sawcer, S. and Hellenthal, G. and Pirinen, M. and Spencer, C.C. and Patsopoulos, N.A. and Moutsianas, L. and Dilthey, A. and Su, Z. and Freeman, C. and Hunt, S.E. and Edkins, S. and Gray, E. and Booth, D.R. and Potter, S.C. and Goris, A. and Band, G. and Oturai, A.B. and Strange, A. and Saarela, J. and Bellenguez, C. and Fontaine, B. and Gillman, M. and Hemmer, B. and Gwilliam, R. and Zipp, F. and Jayakumar, A. and Martin, R. and Leslie, S. and Hawkins, S. and Giannoulatou, E. and D'alfonso, S. and Blackburn, H. and Boneschi, F.M. and Liddle, J. and Harbo, H.F. and Perez, M.L. and Spurkland, A. and Waller, M.J. and Mycko, M.P. and Ricketts, M. and Comabella, M. and Hammond, N. and Kockum, I. and McCann, O.T. and Ban, M. and Whittaker, P. and Kemppinen, A. and Weston, P. and Hawkins, C. and Widaa, S. and Zajicek, J. and Dronov, S. and Robertson, N. and Bumpstead, S.J. and Barcellos, L.F. and Ravindrarajah, R. and Abraham, R. and Alfredsson, L. and Ardlie, K. and Aubin, C. and Baker, A. and Baker, K. and Baranzini, S.E. and Bergamaschi, L. and Bergamaschi, R. and Bernstein, A. and Berthele, A. and Boggild, M. and Bradfield, J.P. and Brassat, D. and Broadley, S.A. and Buck, D. and Butzkueven, H. and Capra, R. and Carroll, W.M. and Cavalla, P. and Celius, E.G. and Cepok, S. and Chiavacci, R. and Clerget-Darpoux, F. and Clysters, K. and Comi, G. and Cossburn, M. and Cournu-Rebeix, I. and Cox, M.B. and Cozen, W. and Cree, B.A. and Cross, A.H. and Cusi, D. and Daly, M.J. and Davis, E. and de Bakker, P.I. and Debouverie, M. and D'hooghe, M.B. and Dixon, K. and Dobosi, R. and Dubois, B. and Ellinghaus, D. and Elovaara, I. and Esposito, F. and Fontenille, C. and Foote, S. and Franke, A. and Galimberti, D. and Ghezzi, A. and Glessner, J. and Gomez, R. and Gout, O. and Graham, C. and Grant, S.F. and Guerini, F.R. and Hakonarson, H. and Hall, P. and Hamsten, A. and Hartung, H.P. and Heard, R.N. and Heath, S. and Hobart, J. and Hoshi, M. and Infante-Duarte, C. and Ingram, G. and Ingram, W. and Islam, T. and Jagodic, M. and Kabesch, M. and Kermode, A.G. and Kilpatrick, T.J. and Kim, C. and Klopp, N. and Koivisto, K. and Larsson, M. and Lathrop, M. and Lechner-Scott, J.S. and Leone, M.A. and Leppa, V. and Liljedahl, U. and Bomfim, I.L. and Lincoln, R.R. and Link, J. and Liu, J. and Lorentzen, A.R. and Lupoli, S. and Macciardi, F. and Mack, T. and Marriott, M. and Martinelli, V. and Mason, D. and McCauley, J.L. and Mentch, F. and Mero, I.L. and Mihalova, T. and Montalban, X. and Mottershead, J. and Myhr, K.M. and Naldi, P. and Ollier, W. and Page, A. and Palotie, A. and Pelletier, J. and Piccio, L. and Pickersgill, T. and Piehl, F. and Pobywajlo, S. and Quach, H.L. and Ramsay, P.P. and Reunanen, M. and Reynolds, R. and Rioux, J.D. and Rodegher, M. and Roesner, S. and Rubio, J.P. and Ruckert, I.M. and Salvetti, M. and Salvi, E. and Santaniello, A. and Schaefer, C.A. and Schreiber, S. and Schulze, C. and Scott, R.J. and Sellebjerg, F. and Selmaj, K.W. and Sexton, D. and Shen, L. and Simms-Acuna, B. and Skidmore, S. and Sleiman, P.M. and Smestad, C. and Sorensen, P.S. and Sondergaard, H.B. and Stankovich, J. and Strange, R.C. and Sulonen, A.M. and Sundqvist, E. and Syvanen, A.C. and Taddeo, F. and Taylor, B. and Blackwell, J.M. and Tienari, P. and Bramon, E. and Tourbah, A. and Brown, M.A. and Tronczynska, E. and Casas, J.P. and Tubridy, N. and Corvin, A. and Vickery, J. and Jankowski, J. and Villoslada, P. and Markus, H.S. and Wang, K. and Mathew, C.G. and Wason, J. and Palmer, C.N. and Wichmann, H.E. and Plomin, R. and Willoughby, E. and Rautanen, A. and Winkelmann, J. and Wittig, M. and Trembath, R.C. and Yaouanq, J. and Viswanathan, A.C. and Zhang, H. and Wood, N.W. and Zuvich, R. and Deloukas, P. and Langford, C. and Duncanson, A. and Oksenberg, J.R. and Pericak-Vance, M.A. and Haines, J.L. and Olsson, T. and Hillert, J. and Ivinson, A.J. and De Jager, P.L. and Peltonen, L. and Stewart, G.J. and Hafler, D.A. and Hauser, S.L. and McVean, G. and Donnelly, P. and Compston, A.
Nature 476 (7359): 214-219. 10 August 2011

2010

Patterns of retinal nerve fiber layer loss in multiple sclerosis patients with or without optic neuritis and glaucoma patients.
Bock, M. and Brandt, A.U. and Doerr, J. and Kraft, H. and Weinges-Evers, N. and Gaede, G. and Pfueller, C.F. and Herges, K. and Radbruch, H. and Ohlraun, S. and Bellmann-Strobl, J. and Kuchenbecker, J. and Zipp, F. and Paul, F.
Clinical Neurology and Neurosurgery 112 (8): 647-652. October 2010

In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis.
Siffrin, V. and Radbruch, H. and Glumm, R. and Niesner, R. and Paterka, M. and Herz, J. and Leuenberger, T. and Lehmann, S.M. and Luenstedt, S. and Rinnenthal, J.L. and Laube, G. and Luche, H. and Lehnardt, S. and Fehling, H.J. and Griesbeck, O. and Zipp, F.
Immunity 33 (3): 424-436. 24 September 2010

Correlation of self-assessed fatigue and alertness in multiple sclerosis.
Weinges-Evers, N. and Brandt, A.U. and Bock, M. and Pfueller, C.F. and Doerr, J. and Bellmann-Strobl, J. and Scherer, P. and Urbanek, C. and Boers, C. and Ohlraun, S. and Zipp, F. and Paul, F.
Multiple Sclerosis 16 (9): 1134-1140. September 2010

Neurodegeneration in autoimmune CNS inflammation.
Herz, J. and Zipp, F. and Siffrin, V.
Experimental Neurology 225 (1): 9-17. September 2010

MAPK3 deficiency drives autoimmunity via dendritic cell arming.
Bendix, I. and Pfueller, C.F. and Leuenberger, T. and Glezeva, N. and Siffrin, V. and Mueller, Y. and Prozorovski, T. and Hansen, W. and Schulze-Topphoff, U. and Loddenkemper, C. and Zipp, F. and Waiczies, S.
European Journal of Immunology 40 (5): 1486-1495. May 2010

Multiple sclerosis - candidate mechanisms underlying CNS atrophy.
Siffrin, V. and Vogt, J. and Radbruch, H. and Nitsch, R. and Zipp, F.
Trends in Neurosciences 33 (4): 202-210. April 2010

No significant effect of orally administered chemokine receptor 1 antagonist on intercellular adhesion molecule-3 expression in relapsing--remitting multiple sclerosis patients.
Reuss, R. and Schreiber, V. and Klein, A. and Infante-Duarte, C. and Filippi, M. and Pabst, W. and Pohl, C. and Oschmann, P.
Multiple Sclerosis 16 (3): 366-369. March 2010

Expanding two-photon intravital microscopy to the infrared by means of optical parametric oscillator.
Herz, J. and Siffrin, V. and Hauser, A.E. and Brandt, A.U. and Leuenberger, T. and Radbruch, H. and Zipp, F. and Niesner, R.A.
Biophysical Journal 98 (4): 715-723. 17 February 2010

MR-elastography reveals degradation of tissue integrity in multiple sclerosis.
Wuerfel, J. and Paul, F. and Beierbach, B. and Hamhaber, U. and Klatt, D. and Papazoglou, S. and Zipp, F. and Martus, P. and Braun, J. and Sack, I.
NeuroImage 49 (3): 2520-2525. 1 February 2010

Dysregulated Epstein-Barr virus infection in patients with CIDP.
Luenemann, J.D. and Tackenberg, B. and Stein, A. and Wandinger, K.P. and Oertel, W.H. and Wagner, H.J. and Muenz, C. and Meisel, H. and Sommer, N. and Zipp, F.
Journal of Neuroimmunology 218 (1-2): 107-111. 25 January 2010

Attention Network Test reveals alerting network dysfunction in multiple sclerosis.
Urbanek, C. and Weinges-Evers, N. and Bellmann-Strobl, J. and Bock, M. and Doerr, J. and Hahn, E. and Neuhaus, A.H. and Opgen-Rhein, C. and Ta, T.M. and Herges, K. and Pfueller, C.F. and Radbruch, H. and Wernecke, K.D. and Ohlraun, S. and Zipp, F. and Dettling, M. and Paul, F.
Multiple Sclerosis 16 (1): 93-99. January 2010

2009

A woman with acute myelopathy in pregnancy: case outcome.
Reuss, R. and Rommer, P.S. and Brueck, W. and Paul, F. and Bolz, M. and Jarius, S. and Boettcher, T. and Grossmann, A. and Bock, A. and Zipp, F. and Benecke, R. and Zettl, U.K.
British Medical Journal 339 : b4026. 10 December 2009

Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death.
Meuth, S.G. and Herrmann, A.M. and Simon, O.J. and Siffrin, V. and Melzer, N. and Bittner, S. and Meuth, P. and Langer, H.F. and Hallermann, S. and Boldakowa, N. and Herz, J. and Munsch, T. and Landgraf, P. and Aktas, O. and Heckmann, M. and Lessmann, V. and Budde, T. and Kieseier, B.C. and Zipp, F. and Wiendl, H.
Journal of Neuroscience 29 (49): 15397-15409. 9 December 2009

Bilateral stroke following pituitary apoplexy.
Lill, C.M. and Hoch, H. and Dieste, F.J. and Vogel, H.P. and Zipp, F. and Paul, F.
Journal of Clinical Neuroscience 16 (12): 1670-1673. December 2009

Encephalopathy, visual disturbance and hearing loss-recognizing the symptoms of Susac syndrome.
Doerr, J. and Radbruch, H. and Bock, M. and Wuerfel, J. and Brueggemann, A. and Wandinger, K.P. and Zeise, D. and Pfueller, C.F. and Zipp, F. and Paul, F.
Nature Reviews Neurology 5 (12): 683-688. December 2009

A woman with acute myelopathy in pregnancy: case progression.
Reuss, R. and Rommer, P.S. and Brueck, W. and Paul, F. and Bolz, M. and Jarius, S. and Boettcher, T. and Grossmann, A. and Bock, A. and Zipp, F. and Benecke, R. and Zettl, U.K.
British Medical Journal 339 : b4025. 19 November 2009

Poor PASAT performance correlates with MRI contrast enhancement in multiple sclerosis.
Bellmann-Strobl, J. and Wuerfel, J. and Aktas, O. and Doerr, J. and Wernecke, K.D. and Zipp, F. and Paul, F.
Neurology 73 (20): 1624-1627. 17 November 2009

A woman with acute myelopathy in pregnancy: case presentation.
Reuss, R. and Rommer, P.S. and Brueck, W. and Paul, F. and Bolz, M. and Jarius, S. and Boettcher, T. and Grossmann, A. and Bock, A. and Zipp, F. and Benecke, R. and Zettl, U.K.
British Medical Journal 339 : b3862. 12 November 2009

Neuromyelitis and more: the unfolding spectrum of aquaporin 4-related neurological diseases.
Aktas, O. and Hartung, H.P.
Journal of Neurology 256 (11): 1906-1908. November 2009

Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment.
Doerr, J. and Bitsch, A. and Schmailzl, K.J. and Chan, A. and von Ahsen, N. and Hummel, M. and Varon, R. and Lill, C.M. and Vogel, H.P. and Zipp, F. and Paul, F.
Neurology 73 (12): 991-993. 22 September 2009

ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis.
Cotte, S. and von Ahsen, N. and Kruse, N. and Huber, B. and Winkelmann, A. and Zettl, U.K. and Starck, M. and Koenig, N. and Tellez, N. and Doerr, J. and Paul, F. and Zipp, F. and Luehder, F. and Koepsell, H. and Pannek, H. and Montalban, X. and Gold, R. and Chan, A.
Brain 132 (Pt 9): 2517-2530. September 2009

Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis.
Vogt, J. and Paul, F.E. and Aktas, O. and Mueller-Wielsch, K. and Doerr, J. and Doerr, S. and Bharathi, B.S. and Glumm, R. and Schmitz, C. and Steinbusch, H. and Raine, C.S. and Tsokos, M. and Nitsch, R. and Zipp, F.
Annals of Neurology 66 (3): 310-322. September 2009

Beyond blood brain barrier breakdown - in vivo detection of occult neuroinflammatory foci by magnetic nanoparticles in high field MRI.
Tysiak, E. and Asbach, P. and Aktas, O. and Waiczies, H. and Smyth, M. and Schnorr, J. and Taupitz, M. and Wuerfel, J.
Journal of Neuroinflammation 6 (1): 20. 6 August 2009

MR spectroscopy (MRS) and magnetisation transfer imaging (MTI), lesion load and clinical scores in early relapsing remitting multiple sclerosis: a combined cross-sectional and longitudinal study.
Bellmann-Strobl, J. and Stiepani, H. and Wuerfel, J. and Bohner, G. and Paul, F. and Warmuth, C. and Aktas, O. and Wandinger, K.P. and Zipp, F. and Klingebiel, R.
European Radiology 19 (8): 2066-2074. August 2009

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in central nervous system inflammation.
Hoffmann, O. and Zipp, F. and Weber, J.R.
Journal of Molecular Medicine 87 (8): 753-763. August 2009

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system.
Schulze-Topphoff, U. and Prat, A. and Prozorovski, T. and Siffrin, V. and Paterka, M. and Herz, J. and Bendix, I. and Ifergan, I. and Schadock, I. and Mori, M.A. and Van Horssen, J. and Schroeter, F. and Smorodchenko, A. and Han, M.H. and Bader, M. and Steinman, L. and Aktas, O. and Zipp, F.
Nature Medicine 15 (7): 788-793. July 2009

Targeting activated microglia in Alzheimer's pathology by intraventricular delivery of a phagocytosable MRI contrast agent in APP23 transgenic mice.
Mundt, A.P. and Winter, C. and Mueller, S. and Wuerfel, J. and Tysiak, E. and Schnorr, J. and Taupitz, M. and Heinz, A. and Juckel, G.
NeuroImage 46 (2): 367-372. June 2009

Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization.
Siffrin, V. and Brandt, A.U. and Radbruch, H. and Herz, J. and Boldakowa, N. and Leuenberger, T. and Werr, J. and Hahner, A. and Schulze-Topphoff, U. and Nitsch, R. and Zipp, F.
Brain 132 (5): 1247-1258. May 2009

United Europeans for development of pharmacogenomics in multiple sclerosis network.
Vandenbroeck, K. and Comabella, M. and Tolosa, E. and Goertsches, R. and Brassat, D. and Hintzen, R. and Infante-Duarte, C. and Favorov, A. and Escorza, S. and Palacios, R. and Oksenberg, J.R. and Villoslada, P.
Pharmacogenomics 10 (5): 885-894. May 2009

A new light source for multimodal multiphoton microscopy including CARS.
Rimke, I. and Siffrin, V. and Niesner, R. and Leuenberger, T. and Zipp, F. and Buttnera, E. and Stibenza, G.
In: Conference on Multiphoton Microscopy in the Biomedical Sciences IX, JAN 25-27, 2009 , San Jose, CA, USA. 13 February 2009

Neuroprotection and enhanced neurogenesis by extract from the tropical plant Knema laurina after inflammatory damage in living brain tissue.
Haeke, I. and Schoenenberger, S. and Neumann, J. and Franke, K. and Paulsen-Merker, K. and Reymann, K. and Ismail, G. and Bin Din, L. and Said, I.M. and Latiff, A. and Wessjohann, L. and Zipp, F. and Ullrich, O.
Journal of Neuroimmunology 206 (1-2): 91-99. 3 January 2009

2008

Therapeutic targeting of chemokine signaling in Multiple Sclerosis.
Hamann, I. and Zipp, F. and Infante-Duarte, C.
Journal of the Neurological Sciences 274 (1-2): 31-38. 15 November 2008

Multiple sclerosis following etanercept treatment for ankylosing spondylitis.
Pfueller, C.F. and Seipelt, E. and Zipp, F. and Paul, F.
Scandinavian Journal of Rheumatology 37 (5): 397-399. September 2008

New developments in understanding and treating neuroinflammation.
Infante-Duarte, C. and Waiczies, S. and Wuerfel, J. and Zipp, F.
Journal of Molecular Medicine 86 (9): 975-985. September 2008

Perivascular spaces - MRI marker of inflammatory activity in the brain?
Wuerfel, J. and Haertle, M. and Waiczies, H. and Tysiak, E. and Bechmann, I. and Wernecke, K.D. and Zipp, F. and Paul, F.
Brain 131 (Pt 9): 2332-2340. September 2008

Autoregulation of Th1-mediated inflammation by twist1.
Niesner, U. and Albrecht, I. and Janke, M. and Doebis, C. and Loddenkemper, C. and Lexberg, M.H. and Eulenburg, K. and Kreher, S. and Koeck, J. and Baumgrass, R. and Bonhagen, K. and Kamradt, T. and Enghard, P. and Humrich, J.Y. and Rutz, S. and Schulze-Topphoff, U. and Aktas, O. and Bartfeld, S. and Radbruch, H. and Hegazy, A.N. and Lohning, M. and Baumgart, D.C. and Duchmann, R. and Rudwaleit, M. and Haupl, T. and Gitelman, I. and Krenn, V. and Gruen, J. and Sieper, J. and Zeitz, M. and Wiedenmann, B. and Zipp, F. and Hamann, A. and Janitz, M. and Scheffold, A. and Burmester, G.R. and Chang, H.D. and Radbruch, A.
Journal of Experimental Medicine 205 (8): 1889-1901. 4 August 2008

Celiac antibodies in the diagnostic workup of white matter lesions.
Paul, F. and Pfueller, C.F. and Wuerfel, J.T. and Egerer, K. and Tanczos, B. and Baumgart, D.C. and Zipp, F.
Neurology 71 (3): 223-225. 15 July 2008

Neues zu Pathogenese, Diagnostik und Therapie der Neuromyelitis optica [Recent findings in pathogenesis, diagnostics and therapy of neuromyelitis optica].
Paul, F. and Jarius, S. and Glumm, R. and Wildemann, B. and Zipp, F. and Aktas, O.
Deutsche Medizinische Wochenschrift 133 (21): 1125-1129. May 2008

Oral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosis.
Paul, F. and Waiczies, S. and Wuerfel, J. and Bellmann-Strobl, J. and Doerr, J. and Waiczies, H. and Haertle, M. and Wernecke, K.D. and Volk, H.D. and Aktas, O. and Zipp, F.
PLoS ONE 3 (4): e1928. 9 April 2008

Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica.
Jarius, S. and Paul, F. and Franciotta, D. and Waters, P. and Zipp, F. and Hohlfeld, R. and Vincent, A. and Wildemann, B.
Nature Clinical Practice Neurology 4 (4): 202-214. April 2008

Sirt1 contributes critically to the redox-dependent fate of neural progenitors.
Prozorovski, T. and Schulze-Topphoff, U. and Glumm, R. and Baumgart, J. and Schroeter, F. and Ninnemann, O. and Siegert, E. and Bendix, I. and Bruestle, O. and Nitsch, R. and Zipp, F. and Aktas, O.
Nature Cell Biology 10 (4): 385-394. April 2008

Treatment-resistant chronic headaches and focal pachymeningitis in a 46-year-old man: a rare presentation of Wegener's granulomatosis.
Doerr, J. and Elitok, S. and Dieste, F.J. and Vogel, H.P. and Schneider, W. and Wuerfel, J. and Zipp, F. and Paul, F.
Lancet Neurology 7 (4): 368-372. April 2008

Geranylgeranylation but not GTP-loading of Rho GTPases determines T cell function.
Waiczies, S. and Bendix, I. and Zipp, F.
Science Signaling 1 (12): pt3. 25 March 2008

Roles of the kallikrein/kinin system in the adaptive immune system.
Schulze-Topphoff, U. and Prat, A. and Bader, M. and Zipp, F. and Aktas, O.
International Immunopharmacology 8 (2): 155-160. February 2008

2007

Neural cell adhesion molecule polysialylation enhances the sensitivity of embryonic stem cell-derived neural precursors to migration guidance cues.
Glaser, T. and Brose, C. and Franceschini, I. and Hamann, K. and Smorodchenko, A. and Zipp, F. and Dubois-Dalcq, M. and Bruestle, O.
Stem Cells 25 (12): 3016-3025. December 2007

Geranylgeranylation but not GTP loading determines rho migratory function in T cells.
Waiczies, S. and Bendix, I. and Prozorovski, T. and Ratner, M. and Nazarenko, I. and Pfueller, C.F. and Brandt, A.U. and Herz, J. and Brocke, S. and Ullrich, O. and Zipp, F.
Journal of Immunology 179 (9): 6024-6032. 1 November 2007

CNS-irrelevant T-cells enter the brain, cause blood-brain barrier disruption but no glial pathology.
Smorodchenko, A. and Wuerfel, J. and Pohl, E.E. and Vogt, J. and Tysiak, E. and Glumm, R. and Hendrix, S. and Nitsch, R. and Zipp, F. and Infante-Duarte, C.
European Journal of Neuroscience 26 (6): 1387-1398. September 2007

Perioperative fluctuations of lamotrigine serum levels in patients undergoing epilepsy surgery.
Paul, F. and Veauthier, C. and Fritz, G. and Lehmann, T.N. and Aktas, O. and Zipp, F. and Meencke, H.J.
Seizure 16 (6): 479-484. September 2007

Cerebral blood perfusion changes in multiple sclerosis.
Wuerfel, J. and Paul, F. and Zipp, F.
Journal of the Neurological Sciences 259 (1-2): 16-20. 15 August 2007

Development of ulcerative colitis in a patient with multiple sclerosis following treatment with interferon beta 1a.
Schott, E. and Paul, F. and Wuerfel, J.T. and Zipp, F. and Rudolph, B. and Wiedenmann, B. and Baumgart, D.C.
World Journal of Gastroenterology 13 (26): 3638-3640. 14 July 2007

TRAIL limits excessive host immune responses in bacterial meningitis.
Hoffmann, O. and Priller, J. and Prozorovski, T. and Schulze-Topphoff, U. and Baeva, N. and Lunemann, J.D. and Aktas, O. and Mahrhofer, C. and Stricker, S. and Zipp, F. and Weber, J.R.
Journal of Clinical Investigation 117 (7): 2004-2013. 2 July 2007

Guillain-Barre-Syndrome: current aspects of pathogenesis, diagnosis, and therapy.
Doerr, J. and Zipp, F.
Nervenheilkunde 26 (7): 560-566. July 2007

Impact of HMG-CoA reductase inhibition on brain pathology.
Zipp, F. and Waiczies, S. and Aktas, O. and Neuhaus, O. and Hemmer, B. and Schraven, B. and Nitsch, R. and Hartung, H.P.
Trends in Pharmacological Sciences 28 (7): 342-349. July 2007

Mouse model mimics multiple sclerosis in the clinico-radiological paradox.
Wuerfel, J. and Tysiak, E. and Prozorovski, T. and Smyth, M. and Mueller, S. and Schnorr, J. and Taupitz, M. and Zipp, F.
European Journal of Neuroscience 26 (1): 190-198. July 2007

Myasthenia gravis - Aktuelle Aspekte der Pathogenese, Diagnostik und Therapie [Myasthenia gravis: current aspects of pathogenesis, diagnosis, and therapy].
Doerr, J. and Zipp, F.
Nervenheilkunde 26 (7): 587-595. July 2007

Classifications and treatment responses in chronic immune-mediated demyelinating polyneuropathy.
Tackenberg, B. and Luenemann, J.D. and Steinbrecher, A. and Rothenfusser-Korber, E. and Sailer, M. and Brueck, W. and Schock, S. and Zschenderlein, R. and Zipp, F. and Sommer, N.
Neurology 68 (19): 1622-1629. 8 May 2007

The role of TRAIL/TRAIL receptors in central nervous system pathology.
Aktas, O. and Schulze-Topphoff, U. and Zipp, F.
Frontiers in Bioscience 12 : 2912-2921. 1 May 2007

Revised diagnostic criteria for neuromyelitis optica - incorporation of NMO-IgG status.
Jarius, S. and Paul, F. and Franciotta, D. and Aktas, O. and Hohlfeld, R. and Zipp, F. and Vincent, A.
Nature Clinical Practice Neurology 3 (5): E1. May 2007

Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica.
Paul, F. and Jarius, S. and Aktas, O. and Bluthner, M. and Bauer, O. and Appelhans, H. and Franciotta, D. and Bergamaschi, R. and Littleton, E. and Palace, J. and Seelig, H.P. and Hohlfeld, R. and Vincent, A. and Zipp, F.
PLoS Medicine 4 (4): e133. April 2007

Tolerogenic effect of fiber tract injury: reduced EAE severity following entorhinal cortex lesion.
Mutlu, L. and Brandt, C. and Kwidzinski, E. and Sawitzki, B. and Gimsa, U. and Mahlo, J. and Aktas, O. and Nitsch, R. and van Zwam, M. and Laman, J.D. and Bechmann, I.
Experimental Brain Research 178 (4): 542-553. April 2007

High-field diffusion tensor imaging of mouse brain in vivo using single-shot STEAM MRI.
Boretius, S. and Wuerfel, J. and Zipp, F. and Frahm, J. and Michaelis, T.
Journal of Neuroscience Methods 161 (1): 112-117. 30 March 2007

Neurodegeneration in autoimmune demyelination: recent mechanistic insights reveal novel therapeutic targets.
Aktas, O. and Waiczies, S. and Zipp, F.
Journal of Neuroimmunology 184 (1-2): 17-26. March 2007

Special issue on inflammation, neurodegeneration and neuroprotection in the central nervous system - Introduction.
Zipp, F. and Trapp, B.D.
Journal of Neuroimmunology 184 (1-2): 1-3. March 2007

Early mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis.
Paul, F. and Doerr, J. and Wuerfel, J. and Vogel, H.P. and Zipp, F.
Journal of Neurology Neurosurgery and Psychiatry 78 (2): 198-200. February 2007

Neuronal damage in brain inflammation.
Aktas, O. and Ullrich, O. and Infante-Duarte, C. and Nitsch, R. and Zipp, F.
Archives of Neurology 64 (2): 185-189. February 2007

Familial effects on the clinical course of multiple sclerosis.
Hensiek, A.E. and Seaman, S.R. and Barcellos, L.F. and Oturai, A. and Eraksoi, M. and Cocco, E. and Vecsei, L. and Stewart, G. and Dubois, B. and Bellman-Strobl, J. and Leone, M. and Andersen, O. and Bencsik, K. and Booth, D. and Celius, E.G. and Harbo, H.F. and Hauser, S.L. and Heard, R. and Hillert, J. and Myhr, K.M. and Marrosu, M.G. and Oksenberg, J.R. and Rajda, C. and Sawcer, S.J. and Sorensen, P.S. and Zipp, F. and Compston, D.A.S.
Neurology 68 (5): 376-383. 30 January 2007

Serum levels of soluble CD95 are not associated with amelioration of multiple sclerosis during pregnancy.
Ehrlich, S. and Haas, J. and Zipp, F. and Infante-Duarte, C.
Journal of the Neurological Sciences 252 (1): 83-87. January 2007

New insights into adaptive immunity in chronic neuroinflammation.
Siffrin, V. and Brandt, A.U. and Herz, J. and Zipp, F.
Advances in Immunology 96 : 1-40. 2007

2006

Blockade of chemokine signaling in patients with multiple sclerosis.
Zipp, F. and Hartung, H.P. and Hillert, J. and Schimrigk, S. and Trebst, C. and Stangel, M. and Infante-Duarte, C. and Jakobs, P. and Wolf, C. and Sandbrink, R. and Pohl, C. and Filippi, M.
Neurology 67 (10): 1880-1883. 28 November 2006

The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases.
Zipp, F. and Aktas, O.
Trends in Neurosciences 29 (9): 518-527. September 2006

2005

Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL.
Aktas, O. and Smorodchenko, A. and Brocke, S. and Infante-Duarte, C. and Schulze Topphoff, U. and Vogt, J. and Prozorovski, T. and Meier, S. and Osmanova, V. and Pohl, E. and Bechmann, I. and Nitsch, R. and Zipp, F.
Neuron 46 (3): 421-432. 5 May 2005