Browse by Research Team

2016

Isolation and cultivation of naive-like human pluripotent stem cells based on HERVH expression.
Wang, J. and Singh, M. and Sun, C. and Besser, D. and Prigione, A. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature Protocols 11 (2): 327-346. February 2016

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.
Klawitter, S. and Fuchs, N.V. and Upton, K.R. and Muñoz-Lopez, M. and Shukla, R. and Wang, J. and Garcia-Cañadas, M. and Lopez-Ruiz, C. and Gerhardt, D.J. and Sebe, A. and Grabundzija, I. and Merkert, S. and Gerdes, P. and Pulgarin, J.A. and Bock, A. and Held, U. and Witthuhn, A. and Haase, A. and Sarkadi, B. and Löwer, J. and Wolvetang, E.J. and Martin, U. and Ivics, Z. and Izsvák, Z. and Garcia-Perez, J.L. and Faulkner, G.J. and Schumann, G.G.
Nature Communications 7 : 10286. 8 January 2016

Pluripotency and the endogenous retrovirus HERVH: Conflict or serendipity?
Izsvák, Z. and Wang, J. and Singh, M. and Mager, D.L. and Hurst, L.D.
BioEssays 38 (1): 109-117. January 2016

2014

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. and Xie, G. and Singh, M. and Ghanbarian, A.T. and Raskó, T. and Szvetnik, A. and Cai, H. and Besser, D. and Prigione, A. and Fuchs, N.V. and Schumann, G.G. and Chen, W. and Lorincz, M.C. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Suicidal autointegration of Sleeping Beauty and piggyBac transposons in eukaryotic cells.
Wang, Y. and Wang, J. and Devaraj, A. and Singh, M. and Jimenez Orgaz, A. and Chen, J.X. and Selbach, M. and Ivics, Z. and Izsvák, Z.
PLoS Genetics 10 (3): e1004103. 13 March 2014

2013

Hybrid adeno-associated viral vectors utilizing transposase-mediated somatic integration for stable transgene expression in human cells.
Zhang, W. and Solanki, M. and Müther, N. and Ebel, M. and Wang, J. and Sun, C. and Izsvak, Z. and Ehrhardt, A.
PLoS ONE 8 (10): e76771. 8 October 2013

Integration profile and safety of an adenovirus hybrid-vector utilizing hyperactive Sleeping Beauty transposase for somatic integration.
Zhang, W. and Muck-Hausl, M. and Wang, J. and Sun, C. and Gebbing, M. and Miskey, C. and Ivics, Z. and Izsvak, Z. and Ehrhardt, A.
PLoS ONE 8 (10): e75344. 4 October 2013

Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells.
Grabundzija, I. and Wang, J. and Sebe, A. and Erdei, Z. and Kajdi, R. and Devaraj, A. and Steinemann, D. and Szuhai, K. and Stein, U. and Cantz, T. and Schambach, A. and Baum, C. and Izsvák, Z. and Sarkadi, B. and Ivics, Z.
Nucleic Acids Research 41 (3): 1829-1847. 1 February 2013