Acta Neuropathologica

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion.
Mitchell, J.C., McGoldrick, P., Vance, C., Hortobagyi, T., Sreedharan, J., Rogelj, B., Tudor, E.L., Smith, B.N., Klasen, C., Miller, C.C.J., Cooper, J.D., Greensmith, L. and Shaw, C.E.
Acta Neuropathologica 125 (2): 273-288. February 2013

Biological Chemistry

Differential regulation of c-Jun and JunD by ubiquitin-dependent protein degradation.
Musti, A.M., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Peverali, F.A. and Bohmann, D.
Biological Chemistry 377 (10): 619-624. October 1996

Cancer Immunology Immunotherapy

Targeting of MYCN by means of DNA vaccination is effective against neuroblastoma in mice.
Stermann, A., Huebener, N., Seidel, D., Fest, S., Eschenburg, G., Stauder, M., Schramm, A., Eggert, A. and Lode, H.N.
Cancer Immunology Immunotherapy 64 (10): 1215-1227. October 2015

Disialoganglioside-specific human natural killer cells are effective against drug-resistant neuroblastoma.
Seidel, D., Shibina, A., Siebert, N., Wels, W.S., Reynolds, C.P., Huebener, N. and Lode, H.N.
Cancer Immunology Immunotherapy 64 (5): 621-634. May 2015

Cell

Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation.
Uhlenhaut, N.H. ORCID: https://orcid.org/0000-0002-4220-4779, Jakob, S., Anlag, K., Eisenberger, T., Sekido, R., Kress, J., Treier, A.C. ORCID: https://orcid.org/0000-0003-1309-6446, Klugmann, C., Klasen, C., Holter, N.I., Riethmacher, D., Schütz, G., Cooney, A.J., Lovell-Badge, R. and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Cell 139 (6): 1130-1142. 11 December 2009

Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types.
Dasen, J.S., O'Connell, S.M., Flynn, S.E., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Gleiberman, A.S., Szeto, D.P., Hooshmand, F., Aggarwal, A.K. and Rosenfeld, M.G.
Cell 97 (5): 587-598. 28 May 1999

JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye.
Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Bohmann, D. and Mlodzik, M.
Cell 83 (5): 753-760. 1 December 1995

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain.
Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Staszewski, L.M. and Bohmann, D.
Cell 78 (5): 787-798. 9 September 1994

Cell Metabolism

A role for brain-specific homeobox factor Bsx in the control of hyperphagia and locomotory behavior.
Sakkou, M., Wiedmer, P., Anlag, K., Hamm, A., Seuntjens, E., Ettwiller, L., Tschöp, M.H. and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Cell Metabolism 5 (6): 450-463. 6 June 2007

Current Opinion in Cell Biology

The hypothalamic-pituitary axis: co-development of two organs.
Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Rosenfeld, M.G.
Current Opinion in Cell Biology 8 (6): 833-843. December 1996

Development

The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei.
Storm, R., Cholewa-Waclaw, J. ORCID: https://orcid.org/0000-0001-8625-8528, Reuter, K., Broehl, D., Sieber, M. ORCID: https://orcid.org/0000-0002-6098-5564, Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Mueller, T. ORCID: https://orcid.org/0000-0001-8096-1853 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Development 136 (2): 295-305. January 2009

Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells.
Gut, P., Huber, K., Lohr, J., Brühl, B., Oberle, S., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Ernsberger, U., Kalcheim, C. and Unsicker, K.
Development 132 (20): 4611-4619. October 2005

The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance.
Schmidt, D., Ovitt, C.E., Anlag, K., Fehsenfeld, S., Gredsted, L., Treier, A.C. and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Development 131 (4): 933-942. 15 February 2004

Hedgehog signaling is required for pituitary gland development.
Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, O'Connell, S., Gleiberman, A., Price, J., Szeto, D.P., Burgess, R., Chuang, P.T., McMahon, A.P. and Rosenfeld, M.G.
Development 128 (3): 377-386. 1 February 2001

Developmental Biology

Transient development of ovotestes in XX Sox9 transgenic mice.
Gregoire, E.P., Lavery, R., Chassot, A.A., Akiyama, H., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Behringer, R.R. and Chaboissier, M.C.
Developmental Biology 349 (1): 65-77. 1 January 2011

Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Zechner, D. ORCID: https://orcid.org/0000-0002-2075-7540, Muller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Walther, I., Taketo, M.M., Crenshaw, E.B., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Developmental Biology 303 (1): 181-190. 1 March 2007

EMBO Journal

Intramolecular signal transduction in c-Jun.
Papavassiliou, A.G., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Bohmann, D.
EMBO Journal 14 (9): 2014-2019. 1 May 1995

Drosophila UbcD1 encodes a highly conserved ubiquitin‐conjugating enzyme involved in selective protein degradation.
Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Seufert, W. and Jentsch, S.
EMBO Journal 11 (1): 367-372. January 1992

Comparison of the gap segmentation gene hunchback between Drosophila melanogaster and Drosophila virilis reveals novel modes of evolutionary change.
Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Pfeifle, C. and Tautz, D.
EMBO Journal 8 (5): 1517-1525. May 1989

EMBO Reports

MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
Kozlowski, M., Corujo, D., Hothorn, M., Guberovic, I., Mandemaker, I.K., Blessing, C., Sporn, J., Gutierrez-Triana, A., Smith, R., Portmann, T., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Scheffzek, K., Huet, S., Timinszky, G., Buschbeck, M. and Ladurner, A.G.
EMBO Reports 19 (10): e44445. 1 October 2018

Endocrinology

Novel candidate regulators and developmental trajectory of pituitary thyrotropes.
Cheung, L.Y.M. ORCID: https://orcid.org/0000-0002-0912-9594, Menage, L., Rizzoti, K., Hamilton, G., Dumontet, T., Basham, K., Daly, A.Z., Brinkmeier, M.L., Masser, B.E., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Cobb, J., Delogu, A., Lovell-Badge, R., Hammer, G.D. and Camper, S.A. ORCID: https://orcid.org/0000-0001-8556-3379
Endocrinology 164 (6): bqad076. June 2023

MicroRNA-7a2 regulates prolactin in developing lactotrophs and prolactinoma cells.
LaPierre, M.P., Godbersen, S., Esteban, M.T., Schad, A.N., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Ghoshdastider, U. and Stoffel, M.
Endocrinology 162 (2): bqaa220. February 2021

Human follicle-stimulating hormone β subunit expression depends on FOXL2 and SMAD4.
Ongaro, L., Schang, G., Zhou, Z., Kumar, T.R., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Deng, C.X., Boehm, U. and Bernard, D.J.
Endocrinology 161 (5): bqaa045. May 2020

Conditional deletion of FOXL2 and SMAD4 in gonadotropes of adult mice causes isolated FSH deficiency.
Li, Y., Schang, G., Wang, Y., Zhou, X., Levasseur, A., Boyer, A., Deng, C.X., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Boehm, U., Boerboom, D. and Bernard, D.J.
Endocrinology 159 (7): 2641-2655. 1 July 2018

Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability.
Nogueiras, R., López, M., Lage, R., Perez-Tilve, D., Pfluger, P., Mendieta-Zerón, H., Sakkou, M., Wiedmer, P., Benoit, S.C., Datta, R., Dong, J.Z., Culler, M., Sleeman, M., Vidal-Puig, A., Horvath, T., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Diéguez, C. and Tschöp, M.H.
Endocrinology 149 (6): 3009-3015. 1 June 2008

FASEB Journal

Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2.
Fortin, J., Boehm, U., Deng, C.X., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Bernard, D.J.
FASEB Journal 28 (8): 3396-3410. August 2014

Genes & Development

The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord.
Muller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Anlag, K., Wildner, H., Britsch, S. ORCID: https://orcid.org/0000-0003-4379-3322, Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 19 (6): 733-743. 1 January 2005

Multistep signaling requirements for pituitary organogenesis in vivo.
Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Gleiberman, A.S., O'Connell, S.M., Szeto, D.P., McMahon, J.A., McMahon, A.P. and Rosenfeld, M.G.
Genes & Development 12 (11): 1691-1704. 1 June 1998

Human Molecular Genetics

Role of Foxl2 in uterine maturation and function.
Bellessort, B., Bachelot, A., Heude, É., Alfama, G., Fontaine, A., Le Cardinal, M., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Levi, G.
Human Molecular Genetics 24 (11): 3092-3103. 1 June 2015

Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis, and epicanthus inversus syndrome.
Heude, É., Bellessort, B., Fontaine, A., Hamazaki, M., Treier, A.C. ORCID: https://orcid.org/0000-0003-1309-6446, Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Levi, G. and Narboux-Neme, N.
Human Molecular Genetics 24 (6): 1670-1681. 15 March 2015

Journal of Biological Chemistry

Identification of a novel family of ubiquitin-conjugating enzymes with distinct amino-terminal extensions.
Matuschewski, K., Hauser, H.P., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Jentsch, S.
Journal of Biological Chemistry 271 (5): 2789-2794. 2 February 1996

Repression of AP-1-stimulated transcription by c-Ets-1.
Goldberg, Y., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Ghysdael, J. and Bohmann, D.
Journal of Biological Chemistry 269 (24): 16566-16573. 17 June 1994

Journal of Comparative Neurology

Characterization of progenitor domains in the developing mouse thalamus.
Vue, T.Y., Aaker, J., Taniguchi, A., Kazemzadeh, C., Skidmore, J.M., Martin, D.M., Martin, J.F., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Nakagawa, Y.
Journal of Comparative Neurology 505 (1): 73-91. 1 November 2007

Journal of Molecular Medicine

Fenretinide sensitizes multidrug-resistant human neuroblastoma cells to antibody-independent and ch14.18-mediated NK cell cytotoxicity.
Shibina, A., Seidel, D., Somanchi, S.S., Lee, D.A., Stermann, A., Maurer, B.J., Lode, H.N., Reynolds, C.P. and Huebener, N.
Journal of Molecular Medicine 91 (4): 459-472. April 2013

Molecular Endocrinology

Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice.
Tran, S., Zhou, X., Lafleur, C., Calderon, M.J., Ellsworth, B.S., Kimmins, S., Boehm, U., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Boerboom, D. and Bernard, D.J.
Molecular Endocrinology 27 (3): 407-421. March 2013

Molecular Genetics and Metabolism

Foxl2 function in ovarian development.
Uhlenhaut, N.H. ORCID: https://orcid.org/0000-0002-4220-4779 and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Molecular Genetics and Metabolism 88 (3): 225-234. July 2006

Nature Communications

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.
Diener, J. ORCID: https://orcid.org/0000-0002-7733-5904, Baggiolini, A. ORCID: https://orcid.org/0000-0002-2476-561X, Pernebrink, M. ORCID: https://orcid.org/0000-0001-5528-3405, Dalcher, D., Lerra, L., Cheng, P.F. ORCID: https://orcid.org/0000-0003-2940-006X, Varum, S., Häusel, J., Stierli, S. ORCID: https://orcid.org/0000-0002-4981-4107, Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Studer, L. ORCID: https://orcid.org/0000-0003-0741-7987, Basler, K., Levesque, M.P., Dummer, R. ORCID: https://orcid.org/0000-0002-2279-6906, Santoro, R. ORCID: https://orcid.org/0000-0001-9894-2896, Cantù, C. ORCID: https://orcid.org/0000-0003-1547-5415 and Sommer, L. ORCID: https://orcid.org/0000-0002-1143-7908
Nature Communications 12 (1): 5056. 20 August 2021

Nature Genetics

Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis.
Attanasio, M., Uhlenhaut, N.H. ORCID: https://orcid.org/0000-0002-4220-4779, Sousa, V.H., O'Toole, J.F., Otto, E., Anlag, K., Klugmann, C., Treier, A.C. ORCID: https://orcid.org/0000-0003-1309-6446, Helou, J., Sayer, J.A., Seelow, D. ORCID: https://orcid.org/0000-0002-9746-4412, Nürnberg, G., Becker, C., Chudley, A.E., Nürnberg, P., Hildebrandt, F. and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Nature Genetics 39 (8): 1018-1024. August 2007

Nature Metabolism

Functional identity of hypothalamic melanocortin neurons depends on Tbx3.
Quarta, C., Fisette, A., Xu, Y., Colldén, G., Legutko, B., Tseng, Y.T., Reim, A., Wierer, M., De Rosa, M.C., Klaus, V., Rausch, R., Thaker, V.V. ORCID: https://orcid.org/0000-0002-3537-2782, Graf, E., Strom, T.M., Poher, A.L., Gruber, T., Le Thuc, O., Cebrian-Serrano, A., Kabra, D., Bellocchio, L., Woods, S.C., Pflugfelder, G.O., Nogueiras, R. ORCID: https://orcid.org/0000-0002-9976-9930, Zeltser, L., Grunwald Kadow, I.C., Moon, A., García-Cáceres, C., Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799, Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Doege, C.A. and Tschöp, M.H. ORCID: https://orcid.org/0000-0002-4744-371X
Nature Metabolism 1 (2): 222-235. February 2019

Nature Methods

BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples.
Hörl, D. ORCID: https://orcid.org/0000-0003-1710-1708, Rojas Rusak, F. ORCID: https://orcid.org/0000-0002-0637-9467, Preusser, F. ORCID: https://orcid.org/0000-0001-8231-2195, Tillberg, P. ORCID: https://orcid.org/0000-0002-2568-2365, Randel, N. ORCID: https://orcid.org/0000-0002-7817-4137, Chhetri, R.K. ORCID: https://orcid.org/0000-0001-6039-4505, Cardona, A. ORCID: https://orcid.org/0000-0001-6039-4505, Keller, P.J. ORCID: https://orcid.org/0000-0003-2896-4920, Harz, H., Leonhardt, H. ORCID: https://orcid.org/0000-0002-5086-6449, Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Preibisch, S. ORCID: https://orcid.org/0000-0002-0276-494X
Nature Methods 16 (9): 870-874. September 2019

Neurogenetics

Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome).
Coldren, C.D., Lai, Z., Shragg, P., Rossi, E., Glidewell, S.C., Zuffardi, O., Mattina, T., Ivy, D.D., Curfs, L.M., Mattson, S.N., Riley, E.P., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Grossfeld, P.D.
Neurogenetics 10 (2): 89-95. April 2009

PLoS ONE

Sexual dimorphic regulation of body weight dynamics and adipose tissue lipolysis.
Benz, V., Bloch, M., Wardat, S., Boehm, C., Maurer, L., Mahmoodzadeh, S. ORCID: https://orcid.org/0000-0002-3094-7874, Wiedmer, P., Spranger, J., Foryst-Ludwig, A. and Kintscher, U.
PLoS ONE 7 (5): e37794. 25 May 2012

Proceedings of the National Academy of Sciences of the United States of America

Murine inner cell mass-derived lineages depend on Sall4 function.
Elling, U., Klasen, C., Eisenberger, T., Anlag, K. and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Proceedings of the National Academy of Sciences of the United States of America 103 (44): 16319-16324. 31 October 2006

Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development.
Kioussi, C., O'Connell, S., St-Onge, L., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Gleiberman, A.S., Gruss, P. and Rosenfeld, M.G.
Proceedings of the National Academy of Sciences of the United States of America 96 (25): 14378-14382. 7 December 1999

Recent Progress in Hormone Research

Multistep signaling and transcriptional requirements for pituitary organogenesis in vivo.
Rosenfeld, M.G., Briata, P., Dasen, J., Gleiberman, A.S., Kioussi, C., Lin, C., O'Connell, S.M., Ryan, A., Szeto, D.P. and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Recent Progress in Hormone Research 55 : 1-13; discussion 13-14. 2000

Reproduction

Forkhead transcription factors in ovarian function.
Uhlenhaut, N.H. ORCID: https://orcid.org/0000-0002-4220-4779 and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Reproduction 142 (4): 489-495. October 2011

Science

Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases.
Musti, A.M., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246 and Bohmann, D.
Science 275 (5298): 400-402. 17 January 1997

Targeted degradation of c-Fos, but not v-Fos, by a phosphorylation-dependent signal on c-Jun.
Papavassiliou, A.G., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Chavrier, C. and Bohmann, D.
Science 258 (5090): 1941-1944. 18 December 1992

Seminars in Cell & Developmental Biology

Molecular mechanisms in renal degenerative disease.
Vasyutina, E. and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Seminars in Cell & Developmental Biology 21 (8): 831-837. October 2010

Sexual Development

Loss of R-spondin1 and Foxl2 amplifies female-to-male sex reversal in XX mice.
Auguste, A., Chassot, A.A., Gregoire, E.P., Renault, L., Pannetier, M., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Pailhoux, E. and Chaboissier, M.C.
Sexual Development 5 (6): 304-317. 22 November 2011

Trends in Genetics

Transcriptional regulators in kidney disease: gatekeepers of renal homeostasis.
Uhlenhaut, N.H. ORCID: https://orcid.org/0000-0002-4220-4779 and Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246
Trends in Genetics 24 (7): 361-371. July 2008

bioRxiv

A human missense variant in BSX decouples circadian behaviour from metabolic rhythmicity while preserving lifespan in mice.
Treier, Anna-Corina ORCID: https://orcid.org/0000-0003-1309-6446, Klasen, Christian, Kramer, Madlen, Schmidt, Deborah ORCID: https://orcid.org/0000-0002-8621-9438, Block, Franziska, Gebhardt, Janine, Rusak, Fabio Rojas ORCID: https://orcid.org/0000-0002-0637-9467, Farooqi, I. Sadaf ORCID: https://orcid.org/0000-0001-7609-3504 and Treier, Mathias ORCID: https://orcid.org/0000-0002-8751-1246
bioRxiv : 2025.12.05.692520. 9 December 2025

eLife

NOTCH activity differentially affects alternative cell fate acquisition and maintenance.
Cheung, L. ORCID: https://orcid.org/0000-0002-0912-9594, Le Tissier, P., Goldsmith, S.G., Treier, M. ORCID: https://orcid.org/0000-0002-8751-1246, Lovell-Badge, R. and Rizzoti, K. ORCID: https://orcid.org/0000-0003-0711-5452
eLife 7 : e33318. 26 March 2018