Browse by Research Team

2024

β(2)-integrins control HIF1α activation in human neutrophils.
Kling, L., Eulenberg-Gustavus, C., Jerke, U., Rousselle, A., Eckardt, K.U., Schreiber, A. and Kettritz, R.
Frontiers in Immunology 15 : 1406967. 14 October 2024

Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange.
Kühne, L., Knöbl, P., Eller, K., Thaler, J., Sperr, W.R., Gleixner, K., Osterholt, T., Kaufeld, J., Menne, J., Buxhofer-Ausch, V., Mühlfeld, A., Seelow, E., Schreiber, A., Todorova, P., Cukoski, S., Jabs, W.J., Özcan, F., Gäckler, A., Schönfelder, K., Seibert, F.S., Westhoff, T., Schwenger, V., Eichenauer, D.A., Völker, L.A. and Brinkkoetter, P.T.
Blood 144 (14): 1486-1495. 3 October 2024

Avacopan in anti-neutrophil cytoplasmic autoantibodies–associated vasculitis in a real-world setting.
Zimmermann, J., Sonnemann, J., Jabs, W.J., Schönermarck, U., Vielhauer, V., Bieringer, M., Schneider, U., Kettritz, R. and Schreiber, A.
Kidney International Reports 9 (9): 2803-2808. September 2024

Die Herausforderung der Lupusnephritis: aktuelle Erkenntnisse und Behandlungsansätze.
Zimmermann, J. and Schreiber, A.
Nephrologie aktuell 28 (6): 248-256. July 2024

Imlifidase – ein innovativer Therapieansatz in der Nephrologie [Imlifidase - an innovative treatment approach in nephrology].
Mestekemper, A.N. and Schreiber, A.
Nephrologie 19 : 248–251. July 2024

Urinary CD4(+) T cells predict renal relapse in ANCA-associated vasculitis: results of the PRE-FLARED study.
Prskalo, L., Skopnik, C.M., Goerlich, N., Freund, P., Wagner, L., Grothgar, E., Mirkheshti, P., Klocke, J., Sonnemann, J., Metzke, D., Schneider, U., Hiepe, F., Eckardt, K.U., Salama, A.D., Bieringer, M., Schreiber, A. and Enghard, P.
Journal of the American Society of Nephrology 35 (4): 483-494. April 2024

CD19-targeting CAR T cells protect from ANCA-induced acute kidney injury.
Lodka, D., Zschummel, M., Bunse, M., Rousselle, A., Sonnemann, J., Kettritz, R., Höpken, U.E. and Schreiber, A.
Annals of the Rheumatic Diseases 83 (4): 499-507. 12 March 2024

2023

Urinary T cells identify renal antineutrophil cytoplasmic antibody-associated vasculitis and predict prognosis: a proof of concept study.
Sonnemann, J., Klocke, J., Bieringer, M., Rousselle, A., Eckardt, K.U., Elitok, S., Popovic, S., Bachmann, S., Kettritz, R., Salama, A.D., Enghard, P. and Schreiber, A.
Kidney International Reports 8 (4): 871-883. April 2023

Impact of first-line use of caplacizumab on treatment outcomes in immune thrombotic thrombocytopenic purpura.
Völker, L.A., Kaufeld, J., Balduin, G., Merkel, L., Kühne, L., Eichenauer, D.A., Osterholt, T., Hägele, H., Kann, M., Grundmann, F., Kolbrink, B., Schulte, K., Gäckler, A., Kribben, A., Boss, K., Potthoff, S.A., Rump, L.C., Schmidt, T., Mühlfeld, A.S., Schulmann, K., Hermann, M., Gaedeke, J., Sauerland, K., Bramstedt, J., Hinkel, U.P., Miesbach, W., Bauer, F., Westhoff, T.H., Bruck, H., Buxhofer-Ausch, V., Müller, T.J., Wendt, R., Harth, A., Schreiber, A., Seelow, E., Tölle, M., Gohlisch, C., Bieringer, M., Geuther, G., Jabs, W.J., Fischereder, M., von Bergwelt-Baildon, A., Schönermarck, U., Knoebl, P., Menne, J. and Brinkkoetter, P.T.
Journal of Thrombosis and Haemostasis 21 (3): 559-572. March 2023

Daratumumab for the treatment of refractory ANCA-associated vasculitis.
Ostendorf, L., Burns, M., Wagner, D.L., Enghard, P., Amann, K., Mei, H., Eckardt, K.U., Seelow, E. and Schreiber, A.
RMD Open 9 (1): e002742. 10 January 2023

2022

Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
Ebert, M.J., Jerke, U., Eulenberg-Gustavus, C., Kling, L., Jenne, D.E., Kirchner, M., Mertins, P., Bieringer, M., Elitok, S., Eckardt, K.U., Schreiber, A., Salama, A.D. and Kettritz, R.
Journal of Clinical Investigation 132 (23): e160089. 1 December 2022

Complement is complimentary in membranous nephropathy.
Kettritz, R. and Schreiber, A.
Journal of the American Society of Nephrology 33 (9): 1631-1633. September 2022

CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Rousselle, A., Sonnemann, J., Amann, K., Mildner, A., Lodka, D., Kling, L., Bieringer, M., Schneider, U., Leutz, A., Enghard, P., Kettritz, R. and Schreiber, A.
Annals of the Rheumatic Diseases 81 (8): 1162-1172. August 2022

Targeting cathepsin C in PR3-ANCA vasculitis.
Jerke, U., Eulenberg-Gustavus, C., Rousselle, A., Nicklin, P., Kreideweiss, S., Grundl, M.A., Eickholz, P., Nickles, K., Schreiber, A., Korkmaz, B. and Kettritz, R.
Journal of the American Society of Nephrology 33 (5): 936-947. May 2022

2021

First diagnosis of thrombotic thrombocytopenic purpura after SARS-CoV-2 vaccine - case report.
Osmanodja, B., Schreiber, A., Schrezenmeier, E. and Seelow, E.
BMC Nephrology 22 (1): 411. 11 December 2021

Imlifidase as novel treatment strategy in anti-neutrophil cytoplasmic antibody–induced pulmonary-renal syndrome.
Enghard, P., Zickler, D., Sonnemann, J., Schneider, W., Lurje, G., Elezkurtaj, S., Eckardt, K.U. and Schreiber, A.
Kidney International 100 (6): 1344-1345. December 2021

Hemophagocytic lymphohistiocytosis and thrombotic microangiopathy after parvovirus B19 infection and renal transplantation: a case report.
Steffen, C.J., Koch, N., Eckardt, K.U., Amann, K., Seelow, E. and Schreiber, A.
BMC Nephrology 22 (1): 337. 12 October 2021

Recurrent early filter clotting during continuous veno-venous hemodialysis with regional citrate anticoagulation is linked to systemic thrombin generation and heparin induced thrombocytopenia type II: a retrospective analysis.
Khadzhynov, D., Slowinski, T., Schreiber, A., Lieker, I., Halleck, F., Lehner, L.J., Kindgen-Milles, D., Eckardt, K.U., Budde, K. and Staeck, O.
Austin Critical Care Case Reports 5 (3): 1032. 30 September 2021

Hypoxia-inducible factors not only regulate but also are myeloid-cell treatment targets.
Kling, L., Schreiber, A., Eckardt, K.U. and Kettritz, R.
Journal of Leukocyte Biology 110 : 61-75. July 2021

Genetic background but not intestinal microbiota after co-housing determines hyperoxaluria-related nephrocalcinosis in common inbred mouse strains.
Ma, Q., Grigorescu, M., Schreiber, A., Kettritz, R., Lindenmeyer, M., Anders, H.J. and Steiger, S.
Frontiers in Immunology 12 : 673423. 21 April 2021

Novichok nerve agent poisoning.
Steindl, D., Boehmerle, W., Körner, R., Praeger, D., Haug, M., Nee, J., Schreiber, A., Scheibe, F., Demin, K., Jacoby, P., Tauber, R., Hartwig, S., Endres, M. and Eckardt, K.U.
Lancet 397 (10270): 249-252. 16 January 2021

Fluorine ((19)F) MRI for assessing inflammatory cells in the kidney: experimental protocol.
Ku, M.C., Schreiber, A., Delgado, P.R., Boehm-Sturm, P., Kettritz, R., Niendorf, T., Pohlmann, A. and Waiczies, S.
Methods in Molecular Biology 2216 : 495-507. 2021

2020

Caplacizumab: frequent local skin reactions.
Kaufeld, J., Brinkkoetter, P.T., Schreiber, A., Jabs, W.J., Bieringer, M., Bruck, H., Menne, J. and Völker, L.A.
Annals of Hematology 100 (12): 3051-3052. December 2020

67-Jährige Patientin mit Sinusitis, Hautvaskulitis und Nierenversagen [67-year-old female patient with sinusitis, skin vasculitis and kidney failure].
Seelow, E., Rudolph, B., Schreiber, A. and Kettritz, R.
Nephrologe 15 (6): 363-365. November 2020

ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP.
Völker, L.A., Kaufeld, J., Miesbach, W., Brähler, S., Reinhardt, M., Kühne, L., Mühlfeld, A., Schreiber, A., Gaedeke, J., Tölle, M., Jabs, W.J., Özcan, F., Markau, S., Girndt, M., Bauer, F., Westhoff, T.H., Felten, H., Hausberg, M., Brand, M., Gerth, J., Bieringer, M., Bommer, M., Zschiedrich, S., Schneider, J., Elitok, S., Gawlik, A., Gäckler, A., Kribben, A., Schwenger, V., Schoenermarck, U., Roeder, M., Radermacher, J., Bramstedt, J., Morgner, A., Herbst, R., Harth, A., Potthoff, S.A., von Auer, C., Wendt, R., Christ, H., Brinkkoetter, P.T. and Menne, J.
Blood Advances 4 (13): 3093-3101. 14 July 2020

Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura.
Völker, L.A., Kaufeld, J., Miesbach, W., Brähler, S., Reinhardt, M., Kühne, L., Mühlfeld, A., Schreiber, A., Gaedeke, J., Tölle, M., Jabs, W.J., Özcan, F., Markau, S., Girndt, M.., Bauer, F., Westhoff, T.H., Felten, H., Hausberg, M., Brand, M., Gerth, J., Bieringer, M., Bommer, M., Zschiedrich, S., Schneider, J., Elitok, S., Gawlik, A., Gäckler, A., Kribben, A., Schwenger, V., Schoenermarck, U., Roeder, M., Radermacher, J., Bramstedt, J., Morgner, A., Herbst, R., Harth, A., Potthoff, S.A., von Auer, C., Wendt, R., Christ, H., Brinkkoetter, P.T. and Menne, J.
Blood Advances 4 (13): 3085-3092. 14 July 2020

Neutrophil gelatinase-associated lipocalin protects from ANCA-induced GN by inhibiting T(H)17 immunity.
Schreiber, A., Rousselle, A., Klocke, J., Bachmann, S., Popovic, S., Bontscho, J., Schmidt-Ott, K.M., Siffrin, V., Jerke, U., Ashraf, M.I., Panzer, U. and Kettritz, R.
Journal of the American Society of Nephrology 31 (7): 1569-1584. July 2020

Clonal hematopoiesis in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis.
Arends, C.M., Weiss, M., Christen, F., Eulenberg-Gustavus, C., Rousselle, A., Kettritz, R., Eckardt, K.U., Chan, W., Hoyer, K., Frick, M., Bullinger, L., Bieringer, M., Schreiber, A. and Damm, F.
Haematologica 105 (6): e264-e267. June 2020

2019

Akutes pulmorenales Syndrom auf der Intensivstation: Rationale Diagnostik und Therapie [Acute pulmonary-renal syndrome in the intensive care unit: rational diagnostics and treatment].
Enghard, P., Erley, C. and Schreiber, A.
Nephrologe 14 : 438-445. 2 October 2019

2018

Therapeutic targeting of cathepsin C: from pathophysiology to treatment.
Korkmaz, B., Caughey, G.H., Chapple, I., Gauthier, F., Hirschfeld, J., Jenne, D.E., Kettritz, R., Lalmanach, G., Lamort, A.S., Lauritzen, C., Legowska, M., Lesner, A., Marchand-Adam, S., McKaig, S.J., Moss, C., Pedersen, J., Roberts, H., Schreiber, A., Seren, S. and Thakkar, N.S.
Pharmacology & Therapeutics 190 : 202-236. October 2018

Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.
Arends, C.M., Galan-Sousa, J., Hoyer, K., Chan, W., Jäger, M., Yoshida, K., Seemann, R., Noerenberg, D., Waldhueter, N., Fleischer-Notter, H., Christen, F., Schmitt, C.A., Dörken, B., Pelzer, U., Sinn, M., Zemojtel, T., Ogawa, S., Märdian, S., Schreiber, A., Kunitz, A., Krüger, U., Bullinger, L., Mylonas, E., Frick, M. and Damm, F.
Leukemia 32 (9): 1908-1919. September 2018

Neuro-Behcet's disease in a patient with thrombotic thrombocytopenic purpura.
Karaivanov, S., Krueger, A., Bethke, N., Radbruch, H., Eckardt, K.U. and Schreiber, A.
Rheumatology 57 (6): 1117-1118. 1 June 2018

Nekroptose und ANCA-assoziierte Vaskulitis [Necroptosis and ANCA-associated vasculitis].
Sonnemann, J., Rousselle, A. and Schreiber, A.
Nephrologe 13 (1): 45-47. January 2018

2017

Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis.
Schreiber, A., Rousselle, A., Becker, J.U., von Mässenhausen, A., Linkermann, A. and Kettritz, R.
Proceedings of the National Academy of Sciences of the United States of America 114 (45): E9618-E9625. 7 November 2017

Endothelial NF-κB blockade abrogates ANCA-induced GN.
Choi, M., Schreiber, A., Eulenberg-Gustavus, C., Scheidereit, C., Kamps, J. and Kettritz, R.
Journal of the American Society of Nephrology 28 (11): 3191-3204. November 2017

Monocytes promote crescent formation in anti-myeloperoxidase antibody-induced glomerulonephritis.
Rousselle, A., Kettritz, R. and Schreiber, A.
American Journal of Pathology 187 (9): 1908-1915. September 2017

2016

Therapeutic complement targeting in ANCA-associated vasculitides and thrombotic microangiopathy.
Novikov, P., Kozlovskaya, N., Moiseev, S., Shilov, E., Bobkova, I., Schreiber, A., Tsvetkov, D., Gollasch, M., Mah, N., El Amrani, K. and Kurtz, A.
Biomedicine Hub 1 (3): 453106. 13 December 2016

Lessons from a double-transgenic neutrophil approach to induce antiproteinase 3 antibody-mediated vasculitis in mice.
Schreiber, A., Eulenberg-Gustavus, C., Bergmann, A., Jerke, U. and Kettritz, R.
Journal of Leukocyte Biology 100 (6): 1443-1452. December 2016

ANCA-associated vasculitis and the mechanisms of tissue injury.
Schreiber, A. and Choi, M.
In: Systemic Vasculitides: Current Status and Perspectives. Springer, Cham, 141-158. ISBN 978-3-319-40134-8 14 October 2016

2015

Advancing cardiovascular, neurovascular, and renal magnetic resonance imaging in small rodents using cryogenic radiofrequency coil technology.
Niendorf, T., Pohlmann, A., Reimann, H.M., Waiczies, H., Peper, E., Huelnhagen, T., Seeliger, E., Schreiber, A., Kettritz, R., Strobel, K., Ku, M.C. and Waiczies, S.
Frontiers in Pharmacology 6 : 255. 12 November 2015

Akutes Nierenversagen bei einem lebertransplantierten Patienten [Acute renal failure in a patient with a liver transplant].
Schreiber, A., Rudolph, B., Kahl, A. and Kettritz, R.
Nephrologe 10 (5): 416-418. September 2015

The case : a 48-year-old man with pulmonary-renal syndrome.
Schreiber, A., Schindler, R., Adcock Funk, D.M. and Kahl, A.
Kidney International 87 (3): 667-668. March 2015

Phagocyte NADPH oxidase restrains the inflammasome in ANCA-induced GN.
Schreiber, A., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 26 (2): 411-424. February 2015

The role of neutrophils in causing antineutrophil cytoplasmic autoantibody-associated vasculitis.
Schreiber, A. and Choi, M.
Current Opinion in Hematology 22 (1): 60-66. January 2015

CD177/NB1 receptor expression is dynamically regulated in sepsis patients.
Schreiber, A., Jannerjahn, A. and Kettritz, R.
Immunohematology 31 (3): 128-129. 2015

2013

The neutrophil in antineutrophil cytoplasmic autoantibody-associated vasculitis.
Schreiber, A. and Kettritz, R.
Journal of Leukocyte Biology 94 (4): 623-631. October 2013

Animal models of ANCA-associated vasculitis: Effector mechanisms and experimental therapies.
Schreiber, A.
Presse Medicale 42 (4 Pt 2): 520-523. April 2013

2012

ANCA-assoziierte Vaskulitiden: Neuere Aspekte der Entstehung [Antineutrophil cytoplasmic antibody-associated vasculitis: novel aspects in the pathogenesis].
Schreiber, A., Choi, M. and Kettritz, R.
Nephrologe 7 (3): 192-199. May 2012

Neutrophil serine proteases promote IL-1beta generation and injury in necrotizing crescentic glomerulonephritis.
Schreiber, A., Pham, C.T., Hu, Y., Schneider, W., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 23 (3): 470-482. March 2012

2011

Myeloperoxidase-specific plasma cell depletion by bortezomib protects from anti-neutrophil cytoplasmic autoantibodies-induced glomerulonephritis.
Bontscho, J., Schreiber, A., Manz, R.A., Schneider, W., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 22 (2): 336-348. February 2011

2010

Phosphoinositol 3-kinase-gamma mediates antineutrophil cytoplasmic autoantibody-induced glomerulonephritis.
Schreiber, A., Rolle, S., Peripelittchenko, L., Rademann, J., Schneider, W., Luft, F.C. and Kettritz, R.
Kidney International 77 (2): 118-128. 2 January 2010

2009

C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis.
Schreiber, A., Xiao, H., Jennette, J.C., Schneider, W., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 20 (2): 289-298. February 2009

2007

Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies.
Xiao, H., Schreiber, A., Heeringa, P., Falk, R.J. and Jennette, J.C.
American Journal of Pathology 170 (1): 52-64. January 2007

2006

Bone marrow-derived cells are sufficient and necessary targets to mediate glomerulonephritis and vasculitis induced by anti-myeloperoxidase antibodies.
Schreiber, A., Xiao, H., Falk, R.J. and Jennette, J.C.
Journal of the American Society of Nephrology 17 (12): 3355-3364. December 2006

2005

Membrane proteinase 3 and Wegener's granulomatosis.
von Vietinghoff, S., Schreiber, A., Otto, B., Choi, M., Goebel, U. and Kettritz, R.
Clinical Nephrology 64 (6): 453-459. 1 January 2005

Membrane proteinase 3 expression in patients with Wegener's granulomatosis and in human hematopoietic stem cell-derived neutrophils.
Schreiber, A., Otto, B., Ju, X., Zenke, M., Goebel, U., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 16 : 2216-2224. 1 January 2005

2004

Pathogenesis of pulmonary vasculitis.
Heeringa, P., Schreiber, A., Falk, R. J. and Jennette, J.C.
Seminars in Respiratory and Critical Care Medicine 25 (5): 465-474. October 2004

Membrane proteinase 3 expression and ANCA-induced neutrophil activation.
Schreiber, A., Luft, F.C. and Kettritz, R.
Kidney International 65 (6): 2172-2183. 1 June 2004

A woman with postoperative hyponatremia related to desmopressin acetate.
Schreiber, A., Kubitza, S. and Luft, F.C.
American Journal of Kidney Diseases 44 (1): E3-E6. 1 January 2004

2003

Solving electrolyte disturbances with the Ehrlich reagent.
Schreiber, A., Elitok, S. and Kettritz, R.
Nephrology Dialysis Transplantation 18 (6): 1217-1219. June 2003

Membrane expression of proteinase 3 is genetically determined.
Schreiber, A., Busjahn, A., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 14 (1): 68-75. 1 January 2003

2001

Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies.
Kettritz, R., Schreiber, A., Luft, F.C. and Haller, H.
Journal of the American Society of Nephrology 12 (1): 37-46. January 2001