Browse by Research Team

ACS Chemical Biology

Chemical proteomics reveals ferrochelatase as a common off-target of kinase inhibitors.
Klaeger, S., Gohlke, B., Perrin, J., Gupta, V., Heinzlmeir, S., Helm, D., Qiao, H., Bergamini, G., Handa, H., Savitski, M.M., Bantscheff, M., Medard, G., Preissner, R. and Kuster, B.
ACS Chemical Biology 11 (5): 1245-1254. 20 May 2016

BMC Bioinformatics

2D and 3D similarity landscape analysis identifies PARP as a novel off-target for the drug Vatalanib.
Gohlke, B.O., Overkamp, T., Richter, A., Richter, A., Daniel, P.T., Gillissen, B. and Preissner, R.
BMC Bioinformatics 16 (1): 308. 24 September 2015

BMC Research Notes

DBEndo: a web-based endodontic case management tool.
Preissner, S., Kostka, E., Mokross, M., Kersten, N.V., Blunck, U. and Preissner, R.
BMC Research Notes 8 : 685. 17 November 2015

Biomedicine & Pharmacotherapy

Anti-diabetic effect of the ethyl acetate fraction of Clerodendrum volubile: protocatechuic acid suppresses phagocytic oxidative burst and modulates inflammatory cytokines.
Erukainure, O.L., Hafizur, R.M., Choudhary, M.I., Adhikari, A., Mesaik, A.M., Atolani, O., Banerjee, P., Preissner, R., Muhammad, A. and Islam, M.S.
Biomedicine & Pharmacotherapy 86 : 307-315. February 2017

Clinical Oral Investigations

Volatile organic compounds in the breath of oral candidiasis patients: a pilot study.
Hertel, M., Schuette, E., Kastner, I., Hartwig, S., Schmidt-Westhausen, A.M., Preissner, R., Paris, S. and Preissner, S.
Clinical Oral Investigations 22 (2): 721-731. March 2018

Clinical and Translational Medicine

Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O., Zincke, F., Eckert, A., Kobelt, D., Preissner, S., Liebeskind, J.M., Gunkel, N., Putzker, K., Lewis, J., Preissner, S., Kortüm, B., Walther, W., Mura, K., Bourne, P.E., Stein, U. and Preissner, R.
Clinical and Translational Medicine 12 (2): e726. 20 February 2022

Current Drug Abuse Reviews

Pain-prescription differences - an analysis of 500,000 discharge summaries.
Preissner, S., Siramshetty, V.B., Dunkel, M., Steinborn, P., Luft, F.C. and Preissner, R.
Current Drug Abuse Reviews 11 (1): 58-66. 2019

Drug Discovery Today

Drugs as habitable planets in the space of dark chemical matter.
Siramshetty, V.B. and Preissner, R.
Drug Discovery Today 23 (3): 481-486. March 2018

European Journal of Clinical Microbiology & Infectious Diseases

Detection of signature volatiles for cariogenic microorganisms.
Hertel, M., Preissner, R., Gillissen, B., Schmidt-Westhausen, A.M., Paris, S. and Preissner, S.
European Journal of Clinical Microbiology & Infectious Diseases 35 (2): 235-244. February 2016

Food and Chemical Toxicology

Computational prediction of immune cell cytotoxicity.
Schrey, A.K., Nickel-Seeber, J., Drwal, M.N., Zwicker, P., Schultze, N., Haertel, B. and Preissner, R.
Food and Chemical Toxicology 107 (Part A): 150-166. September 2017

Frontiers in Chemistry

BitterSweetForest: a Random Forest based binary classifier to predict bitterness and sweetness of chemical compounds.
Banerjee, P. and Preissner, R.
Frontiers in Chemistry 6 : 93. April 2018

International Journal of Molecular Sciences

Norditerpenoids with selective anti-cholinesterase activity from the roots of Perovskia atriplicifolia Benth.
Ślusarczyk, S., Senol Deniz, F.S., Abel, R., Pecio, Ł., Pérez-Sánchez, H., Cerón-Carrasco, J.P., den-Haan, H., Banerjee, P., Preissner, R., Krzyżak, E., Oleszek, W., E Orhan, I. and Matkowski, A.
International Journal of Molecular Sciences 21 (12): 4475. 23 June 2020

Journal of Biological Chemistry

Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B., Richter, A., Richter, A., Preissner, R., Schulze-Osthoff, K., Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292 (16): 6478-6492. 21 April 2017

Journal of Cheminformatics

Computational methods for prediction of in vitro effects of new chemical structures.
Banerjee, P., Siramshetty, V.B., Drwal, M.N. and Preissner, R.
Journal of Cheminformatics 8 (1): 51. 29 September 2016

Journal of the American Society of Nephrology

TRPC6 G757D loss-of-function mutation associates with FSGS.
Riehle, M., Büscher, A.K., Gohlke, B.O., Kaßmann, M., Kolatsi-Joannou, M., Bräsen, J.H., Nagel, M., Becker, J.U., Winyard, P., Hoyer, P.F., Preissner, R., Krautwurst, D., Gollasch, M., Weber, S. and Harteneck, C.
Journal of the American Society of Nephrology 27 (9): 2771-2783. September 2016

Mycoses

Identification of signature volatiles to discriminate Candida albicans, glabrata, krusei and tropicalis using gas chromatography and mass spectrometry.
Hertel, M., Hartwig, S., Schuette, E., Gillissen, B., Preissner, R., Schmidt-Westhausen, A.M., Paris, S., Kastner, I. and Preissner, S.
Mycoses 59 (2): 117-126. February 2016

Natural Products and Bioprospecting

Inhibition of DNA-topoisomerase I by acylated triterpene saponins from pittosporum angustifolium Lodd.
Baecker, C., Drwal, M.N., Preissner, R. and Lindequist, U.
Natural Products and Bioprospecting 6 (2): 141-147. April 2016

Nucleic Acids Research

SuperCYPsPred - a web server for the prediction of cytochrome activity.
Banerjee, P., Dunkel, M., Kemmler, E. and Preissner, R.
Nucleic Acids Research 48 (W1): W580-W585. July 2020

ProTox-II: a webserver for the prediction of toxicity of chemicals.
Banerjee, P., Eckert, A.O., Schrey, A.K. and Preissner, R.
Nucleic Acids Research 46 (W1): W257-W263. 2 July 2018

SuperDRUG2: a one stop resource for approved/marketed drugs.
Siramshetty, V.B., Eckert, O.A., Gohlke, B.O., Goede, A., Chen, Q., Devarakonda, P., Preissner, S. and Preissner, R.
Nucleic Acids Research 46 (D1): D1137-D1143. 4 January 2018

mVOC 2.0: a database of microbial volatiles.
Lemfack, M.C., Gohlke, B.O., Toguem, S.M.T., Preissner, S., Piechulla, B. and Preissner, R.
Nucleic Acids Research 46 (D1): D1261-D1265. 4 January 2018

SL2: an interactive webtool for modeling of missing segments in proteins.
Ismer, J., Rose, A.S., Tiemann, J.K.S., Goede, A., Preissner, R. and Hildebrand, P.W.
Nucleic Acids Research 44 (W1): W390-W394. 8 July 2016

CancerResource - updated database of cancer-relevant proteins, mutations and interacting drugs.
Gohlke, B.O., Nickel, J., Otto, R., Dunkel, M. and Preissner, R.
Nucleic Acids Research 44 (D1): D932-D937. 4 January 2016

WITHDRAWN-a resource for withdrawn and discontinued drugs.
Siramshetty, V.B., Nickel, J., Omieczynski, C., Gohlke, B.O., Drwal, M.N. and Preissner, R.
Nucleic Acids Research 44 (D1): D1080-D1086. 4 January 2016

Super natural II -a database of natural products.
Banerjee, P., Erehman, J., Gohlke, B.O., Wilhelm, T., Preissner, R. and Dunkel, M.
Nucleic Acids Research 43 (Database issue): D935-D939. 28 January 2015

The Transformer database: biotransformation of xenobiotics.
Hoffmann, M.F., Preissner, S.C., Nickel, J., Dunkel, M., Preissner, R. and Preissner, S.
Nucleic Acids Research 42 (1): D1113-D1117. 1 January 2014

mVOC: a database of microbial volatiles.
Lemfack, M.C., Nickel, J., Dunkel, M., Preissner, R. and Piechulla, B.
Nucleic Acids Research 42 (1): D744-D748. 1 January 2014

PLoS Biology

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.
Juneja, M., Kobelt, D., Walther, W., Voss, C., Smith, J., Specker, E., Neuenschwander, M., Gohlke, B.O., Dahlmann, M., Radetzki, S., Preissner, R., von Kries, J.P., Schlag, P.M. and Stein, U.
PLoS Biology 15 (6): e2000784. 1 June 2017

PLoS ONE

Acyclovir has low but detectable influence on HLA-B*57:01 specificity without inducing hypersensitivity.
Metushi, I.G., Wriston, A., Banerjee, P., Gohlke, B.O., English, A.M., Lucas, A., Moore, C., Sidney, J., Buus, S., Ostrov, D.A., Mallal, S., Phillips, E., Shabanowitz, J., Hunt, D.F., Preissner, R. and Peters, B.
PLoS ONE 10 (5): e0124878. 29 May 2015

Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy.
Preissner, S.C., Hoffmann, M.F., Preissner, R., Dunkel, M., Gewiess, A. and Preissner, S.
PLoS ONE 8 (12): e82562. 10 December 2013