Browse by Research Team

Article

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
Yeh, Y.T., Sona, C., Yan, X., Li, Y., Pathak, A., McDermott, M.I., Xie, Z., Liu, L., Arunagiri, A., Wang, Y., Cazenave-Gassiot, A., Ghosh, A., von Meyenn, F., Kumarasamy, S., Najjar, S.M., Jia, S., Wenk, M.R., Traynor-Kaplan, A., Arvan, P., Barg, S., Bankaitis, V.A. and Poy, M.N.
Nature Communications 14 (1): 4250. 17 July 2023

Stimulation of mGluR1/5 improves defective internalization of AMPA receptors in NPC1 mutant mouse.
Feng, X., Yang, F., Rabenstein, M., Wang, Z., Frech, M.J., Wree, A., Bräuer, A.U., Witt, M., Gläser, A., Hermann, A., Rolfs, A. and Luo, J.
Cerebral Cortex 30 (3): 1465-1480. March 2020

Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J., Neukam, M., Tattikota, S.G., Qadri, F., Puchkov, D., Willmes, D.M., Wurmsee, S., Geisberger, S., Dechend, R., Raile, K., Kurth, T., Nguyen, G., Poy, M.N., Solimena, M., Muller, D.N. and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116 (40): 19983-19988. 1 October 2019

Control of hepatic gluconeogenesis by Argonaute2.
Yan, X., Wang, Z., Bishop, C.A., Weitkunat, K., Feng, X., Tarbier, M., Luo, J., Friedländer, M.R., Burkhardt, R., Klaus, S., Willnow, T.E. and Poy, M.N.
Molecular Metabolism 18 : 15-24. December 2018

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.
Subkhangulova, A., Malik, A.R., Hermey, G., Popp, O., Dittmar, G., Rathjen, T., Poy, M.N., Stumpf, A., Beed, P.S., Schmitz, D., Breiderhoff, T. and Willnow, T.E.
EMBO Reports 19 (4): e44810. 1 April 2018

Neuronal cell adhesion molecule 1 regulates leptin sensitivity and bone mass.
Yan, X., Kononenko, N.L., Brueel, A., Thomsen, J.S. and Poy, M.N.
Calcified Tissue International 102 (3): 329-336. March 2018

Cadm2 regulates body weight and energy homeostasis in mice.
Yan, X., Wang, Z., Schmidt, V., Gauert, A., Willnow, T.E., Heinig, M. and Poy, M.N.
Molecular Metabolism 8 : 180-188. February 2018

The RhoGAP Stard13 controls insulin secretion through F-actin remodeling.
Naumann, H., Rathjen, T., Poy, M.N. and Spagnoli, F.M.
Molecular Metabolism 8 : 96-105. February 2018

microRNA-184 induces a commitment switch to epidermal differentiation.
Nagosa, S., Leesch, F., Putin, D., Bhattacharya, S., Altshuler, A., Serror, L., Amitai-Lange, A., Nasser, W., Aberdam, E., Rouleau, M., Tattikota, S.G., Poy, M.N., Aberdam, D. and Shalom-Feuerstein, R.
Stem Cell Reports 9 (6): 1991-2004. 12 December 2017

Differential impact of glucose administered intravenously and orally on circulating mir-375 levels in human subjects.
Yan, X., Wang, Z., Westberg-Rasmussen, S., Tarbier, M., Rathjen, T., Tattikota, S.G., Peck, B.C.E., Kanke, M., Oxvig, C., Frystyk, J., Starup-Linde, J., Sethupathy, P., Friedlaender, M.R., Gregersen, S. and Poy, M.N.
Journal of Clinical Endocrinology and Metabolism 102 (10): 3749-3755. 1 October 2017

Pregnancy-associated plasma protein-A2 and anthropometry, lifestyle, and biochemical factors in a human adult population.
Steinbrecher, A., Janke, J., Poy, M.N., Oxvig, C. and Pischon, T.
Scientific Reports 7 (1): 10455. 5 September 2017

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.
Rathjen, T., Yan, X., Kononenko, N.L., Ku, M.C., Song, K., Ferrarese, L., Tarallo, V., Puchkov, D., Kochlamazashvili, G., Brachs, S., Varela, L., Szigeti-Buck, K., Yi, C.X., Schriever, S.C., Tattikota, S.G., Carlo, A.S., Moroni, M., Siemens, J., Heuser, A., van der Weyden, L., Birkenfeld, A.L., Niendorf, T., Poulet, J.F.A., Horvath, T.L., Tschöp, M.H., Heinig, M., Trajkovski, M., Haucke, V. and Poy, M.N.
Nature Neuroscience 20 (8): 1096-1103. August 2017

MicroRNAs: an adaptive mechanism in the pancreatic β-cell…and beyond?
Poy, M.N.
Best Practice & Research Clinical Endocrinology & Metabolism 30 (5): 621-628. October 2016

SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity.
Schmidt, V., Schulz, N., Yan, X., Schürmann, A., Kempa, S., Kern, M., Blüher, M., Poy, M.N., Olivecrona, G. and Willnow, T.E.
Journal of Clinical Investigation 126 (7): 2706-2720. 1 July 2016

The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.
Czimmerer, Z., Varga, T., Kiss, M., Vazquez, C.O., Doan-Xuan, Q.M., Rueckerl, D., Tattikota, S.G., Yan, X., Nagy, Z.S., Daniel, B., Poliska, S., Horvath, A., Nagy, G., Varallyay, E., Poy, M.N., Allen, J.E., Bacso, Z., Abreu-Goodger, C. and Nagy, L.
Genome Medicine 8 (1): 63. 31 May 2016

miR-184 regulates pancreatic β-cell function according to glucose metabolism.
Tattikota, S.G., Rathjen, T., Hausser, J., Khedkar, A., Kabra, U.D., Pandey, V.K., Sury, M.D., Wessels, H.H., Mollet, I.G., Eliasson, L., Selbach, M., Zinzen, R.P., Zavolan, M., Kadener, S., Tschöp, M., Jastroch, M., Friedländer, M.R. and Poy, M.N.
Journal of Biological Chemistry 290 (33): 20284-20294. 14 August 2015

Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.
Jia, S., Ivanov, A., Blasevic, D., Müller, T., Purfürst, B., Sun, W., Chen, W., Poy, M.N., Rajewsky, N. and Birchmeier, C.
EMBO Journal 34 (10): 1417-1433. 12 May 2015

Argonaute2 mediates compensatory expansion of the pancreatic β cell.
Tattikota, S.G., Rathjen, T., McAnulty, S.J., Wessels, H.H., Akerman, I., van de Bunt, M., Hausser, J., Esguerra, J.L.S., Musahl, A., Pandey, A.K., You, X., Chen, W., Herrera, P.L., Johnson, P.R., O'Carroll, D., Eliasson, L., Zavolan, M., Gloyn, A.L., Ferrer, J., Shalom-Feuerstein, R., Aberdam, D. and Poy, M.N.
Cell Metabolism 19 (1): 122-134. 7 January 2014

Argonaute2 regulates the pancreatic β-cell secretome.
Tattikota, S.G., Sury, M.D., Rathjen, T., Wessels, H.H., Pandey, A.K., You, X., Becker, C., Chen, W., Selbach, M. and Poy, M.N.
Molecular & Cellular Proteomics 12 (5): 1214-1225. May 2013

Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.
Biton, M., Levin, A., Slyper, M., Alkalay, I., Horwitz, E., Mor, H., Kredo-Russo, S., Avnit-Sagi, T., Cojocaru, G., Zreik, F., Bentwich, Z., Poy, M.N., Artis, D., Walker, M.D., Hornstein, E., Pikarsky, E. and Ben-Neriah, Y.
Nature Immunology 12 (3): 239-246. March 2011

miR-375 maintains normal pancreatic α- and β-cell mass.
Poy, M.N., Hausser, J., Trajkovski, M., Braun, M., Collins, S., Rorsman, P., Zavolan, M. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (14): 5813-5818. 7 April 2009

Editorial

Micro-managing the pancreatic β cell.
Rathjen, T., Tattikota, S.G. and Poy, M.N.
Cell Cycle 13 (8): 1216-1217. 15 April 2014

Re-dicing the pancreatic beta-cell: do microRNAs define cellular identity?
Tattikota, S.G. and Poy, M.N.
EMBO Journal 30 (5): 797-799. 2 March 2011