Article

Glutamatergic argonaute2 promotes the formation of the neurovascular unit in mice.
Sona, C. ORCID: https://orcid.org/0000-0003-3107-016X, Yeh, Y.T. ORCID: https://orcid.org/0000-0001-7968-6081, Li, Y. ORCID: https://orcid.org/0009-0006-6992-9098, Liu, X., Ghosh, A. ORCID: https://orcid.org/0000-0002-5160-4571, Hinte, L.C. ORCID: https://orcid.org/0000-0002-4226-0009, Ku, M.C. ORCID: https://orcid.org/0000-0003-0963-2461, Rathjen, T., Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Yu, G. ORCID: https://orcid.org/0000-0002-5194-8614, Jia, S. ORCID: https://orcid.org/0000-0001-8595-9314, Kononenko, N.L., Hermann, A. ORCID: https://orcid.org/0000-0002-7364-7791, Luo, J. ORCID: https://orcid.org/0000-0001-5169-3095, Lin, J. ORCID: https://orcid.org/0000-0001-9300-1771, von Meyenn, F. ORCID: https://orcid.org/0000-0001-9920-3075, Yan, X. ORCID: https://orcid.org/0000-0002-9135-7915 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Science Signaling 18 (875): eadl6745. 25 February 2025

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
Yeh, Y.T., Sona, C., Yan, X. ORCID: https://orcid.org/0000-0002-9135-7915, Li, Y., Pathak, A., McDermott, M.I., Xie, Z., Liu, L., Arunagiri, A. ORCID: https://orcid.org/0000-0001-9839-1860, Wang, Y., Cazenave-Gassiot, A. ORCID: https://orcid.org/0000-0002-3050-634X, Ghosh, A. ORCID: https://orcid.org/0000-0002-5160-4571, von Meyenn, F. ORCID: https://orcid.org/0000-0001-9920-3075, Kumarasamy, S., Najjar, S.M., Jia, S. ORCID: https://orcid.org/0000-0001-8595-9314, Wenk, M.R., Traynor-Kaplan, A., Arvan, P. ORCID: https://orcid.org/0000-0002-4007-8799, Barg, S. ORCID: https://orcid.org/0000-0003-4661-5724, Bankaitis, V.A. ORCID: https://orcid.org/0000-0002-1654-6759 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Nature Communications 14 (1): 4250. 17 July 2023

Stimulation of mGluR1/5 improves defective internalization of AMPA receptors in NPC1 mutant mouse.
Feng, X., Yang, F., Rabenstein, M., Wang, Z. ORCID: https://orcid.org/0000-0002-7351-602X, Frech, M.J., Wree, A., Bräuer, A.U., Witt, M., Gläser, A., Hermann, A., Rolfs, A. and Luo, J.
Cerebral Cortex 30 (3): 1465-1480. March 2020

Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J. ORCID: https://orcid.org/0000-0003-1139-3308, Neukam, M., Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533, Qadri, F. ORCID: https://orcid.org/0000-0002-8500-489X, Puchkov, D., Willmes, D.M., Wurmsee, S., Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Raile, K. ORCID: https://orcid.org/0000-0002-0842-1737, Kurth, T., Nguyen, G., Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Solimena, M., Muller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644 and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116 (40): 19983-19988. 1 October 2019

Control of hepatic gluconeogenesis by Argonaute2.
Yan, X. ORCID: https://orcid.org/0000-0002-9135-7915, Wang, Z. ORCID: https://orcid.org/0000-0002-7351-602X, Bishop, C.A. ORCID: https://orcid.org/0000-0003-2247-3602, Weitkunat, K., Feng, X., Tarbier, M., Luo, J., Friedländer, M.R. ORCID: https://orcid.org/0000-0001-6577-4363, Burkhardt, R., Klaus, S., Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Molecular Metabolism 18 : 15-24. December 2018

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.
Subkhangulova, A. ORCID: https://orcid.org/0000-0001-8843-0678, Malik, A.R. ORCID: https://orcid.org/0000-0001-7732-0756, Hermey, G. ORCID: https://orcid.org/0000-0003-4762-5262, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Rathjen, T., Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Stumpf, A., Beed, P.S., Schmitz, D. ORCID: https://orcid.org/0000-0003-2741-5241, Breiderhoff, T. ORCID: https://orcid.org/0000-0002-1676-7498 and Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921
EMBO Reports 19 (4): e44810. 1 April 2018

Neuronal cell adhesion molecule 1 regulates leptin sensitivity and bone mass.
Yan, X. ORCID: https://orcid.org/0000-0002-9135-7915, Kononenko, N.L., Brueel, A. ORCID: https://orcid.org/0000-0003-4833-0888, Thomsen, J.S. ORCID: https://orcid.org/0000-0001-9386-6679 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Calcified Tissue International 102 (3): 329-336. March 2018

Cadm2 regulates body weight and energy homeostasis in mice.
Yan, X. ORCID: https://orcid.org/0000-0002-9135-7915, Wang, Z. ORCID: https://orcid.org/0000-0002-7351-602X, Schmidt, V. ORCID: https://orcid.org/0000-0002-5851-1087, Gauert, A. ORCID: https://orcid.org/0000-0002-3013-5374, Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921, Heinig, M. ORCID: https://orcid.org/0000-0002-5612-1720 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Molecular Metabolism 8 : 180-188. February 2018

The RhoGAP Stard13 controls insulin secretion through F-actin remodeling.
Naumann, H. ORCID: https://orcid.org/0000-0003-3883-0432, Rathjen, T., Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426 and Spagnoli, F.M. ORCID: https://orcid.org/0000-0001-7094-8188
Molecular Metabolism 8 : 96-105. February 2018

microRNA-184 induces a commitment switch to epidermal differentiation.
Nagosa, S., Leesch, F., Putin, D., Bhattacharya, S., Altshuler, A., Serror, L., Amitai-Lange, A., Nasser, W., Aberdam, E., Rouleau, M., Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533, Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Aberdam, D. and Shalom-Feuerstein, R.
Stem Cell Reports 9 (6): 1991-2004. 12 December 2017

Differential impact of glucose administered intravenously and orally on circulating mir-375 levels in human subjects.
Yan, X. ORCID: https://orcid.org/0000-0002-9135-7915, Wang, Z. ORCID: https://orcid.org/0000-0002-7351-602X, Westberg-Rasmussen, S., Tarbier, M., Rathjen, T., Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533, Peck, B.C.E., Kanke, M., Oxvig, C., Frystyk, J., Starup-Linde, J., Sethupathy, P., Friedlaender, M.R. ORCID: https://orcid.org/0000-0001-6577-4363, Gregersen, S. and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Journal of Clinical Endocrinology and Metabolism 102 (10): 3749-3755. 1 October 2017

Pregnancy-associated plasma protein-A2 and anthropometry, lifestyle, and biochemical factors in a human adult population.
Steinbrecher, A. ORCID: https://orcid.org/0000-0001-5640-5742, Janke, J. ORCID: https://orcid.org/0000-0003-0113-4118, Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Oxvig, C. ORCID: https://orcid.org/0000-0002-4715-9719 and Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X
Scientific Reports 7 (1): 10455. 5 September 2017

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.
Rathjen, T., Yan, X. ORCID: https://orcid.org/0000-0002-9135-7915, Kononenko, N.L., Ku, M.C. ORCID: https://orcid.org/0000-0003-0963-2461, Song, K. ORCID: https://orcid.org/0000-0001-6216-8157, Ferrarese, L. ORCID: https://orcid.org/0000-0001-9098-5357, Tarallo, V., Puchkov, D., Kochlamazashvili, G., Brachs, S., Varela, L., Szigeti-Buck, K., Yi, C.X., Schriever, S.C. ORCID: https://orcid.org/0000-0001-5461-3214, Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533, Carlo, A.S., Moroni, M. ORCID: https://orcid.org/0000-0002-2389-3468, Siemens, J., Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, van der Weyden, L., Birkenfeld, A.L. ORCID: https://orcid.org/0000-0003-1407-9023, Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Poulet, J.F.A. ORCID: https://orcid.org/0000-0003-0296-5415, Horvath, T.L., Tschöp, M.H., Heinig, M. ORCID: https://orcid.org/0000-0002-5612-1720, Trajkovski, M., Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Nature Neuroscience 20 (8): 1096-1103. August 2017

MicroRNAs: an adaptive mechanism in the pancreatic β-cell…and beyond?
Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Best Practice & Research Clinical Endocrinology & Metabolism 30 (5): 621-628. October 2016

SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity.
Schmidt, V. ORCID: https://orcid.org/0000-0002-5851-1087, Schulz, N., Yan, X. ORCID: https://orcid.org/0000-0002-9135-7915, Schürmann, A., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Kern, M., Blüher, M., Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Olivecrona, G. and Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921
Journal of Clinical Investigation 126 (7): 2706-2720. 1 July 2016

The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.
Czimmerer, Z., Varga, T., Kiss, M., Vazquez, C.O., Doan-Xuan, Q.M., Rueckerl, D., Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533, Yan, X., Nagy, Z.S., Daniel, B., Poliska, S., Horvath, A., Nagy, G., Varallyay, E., Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Allen, J.E., Bacso, Z., Abreu-Goodger, C. and Nagy, L.
Genome Medicine 8 (1): 63. 31 May 2016

miR-184 regulates pancreatic β-cell function according to glucose metabolism.
Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533, Rathjen, T., Hausser, J., Khedkar, A., Kabra, U.D., Pandey, V.K., Sury, M.D., Wessels, H.H. ORCID: https://orcid.org/0000-0001-5551-404X, Mollet, I.G., Eliasson, L., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Zinzen, R.P. ORCID: https://orcid.org/0000-0002-8638-5102, Zavolan, M., Kadener, S., Tschöp, M., Jastroch, M., Friedländer, M.R. ORCID: https://orcid.org/0000-0001-6577-4363 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Journal of Biological Chemistry 290 (33): 20284-20294. 14 August 2015

Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.
Jia, S. ORCID: https://orcid.org/0000-0001-8595-9314, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Blasevic, D., Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Sun, W. ORCID: https://orcid.org/0000-0001-9607-1361, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
EMBO Journal 34 (10): 1417-1433. 12 May 2015

Argonaute2 mediates compensatory expansion of the pancreatic β cell.
Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533, Rathjen, T., McAnulty, S.J., Wessels, H.H. ORCID: https://orcid.org/0000-0001-5551-404X, Akerman, I., van de Bunt, M., Hausser, J., Esguerra, J.L.S., Musahl, A., Pandey, A.K. ORCID: https://orcid.org/0000-0002-8886-1694, You, X. ORCID: https://orcid.org/0000-0002-1684-7084, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Herrera, P.L., Johnson, P.R., O'Carroll, D., Eliasson, L., Zavolan, M., Gloyn, A.L., Ferrer, J., Shalom-Feuerstein, R., Aberdam, D. and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Cell Metabolism 19 (1): 122-134. 7 January 2014

Argonaute2 regulates the pancreatic β-cell secretome.
Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533, Sury, M.D., Rathjen, T., Wessels, H.H. ORCID: https://orcid.org/0000-0001-5551-404X, Pandey, A.K. ORCID: https://orcid.org/0000-0002-8886-1694, You, X. ORCID: https://orcid.org/0000-0002-1684-7084, Becker, C., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Molecular & Cellular Proteomics 12 (5): 1214-1225. May 2013

Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.
Biton, M., Levin, A., Slyper, M., Alkalay, I., Horwitz, E., Mor, H., Kredo-Russo, S., Avnit-Sagi, T., Cojocaru, G., Zreik, F., Bentwich, Z., Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Artis, D., Walker, M.D., Hornstein, E., Pikarsky, E. and Ben-Neriah, Y.
Nature Immunology 12 (3): 239-246. March 2011

miR-375 maintains normal pancreatic α- and β-cell mass.
Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Hausser, J., Trajkovski, M., Braun, M., Collins, S., Rorsman, P., Zavolan, M. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (14): 5813-5818. 7 April 2009

Editorial

Micro-managing the pancreatic β cell.
Rathjen, T., Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
Cell Cycle 13 (8): 1216-1217. 15 April 2014

Re-dicing the pancreatic beta-cell: do microRNAs define cellular identity?
Tattikota, S.G. ORCID: https://orcid.org/0000-0003-0318-5533 and Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426
EMBO Journal 30 (5): 797-799. 2 March 2011