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2021

Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes.
Pishesha, N. and Harmand, T. and Smeding, L.Y. and Ma, W. and Ludwig, L.S. and Janssen, R. and Islam, A. and Xie, Y.J. and Fang, T. and McCaul, N. and Pinney, W. and Sugito, H.R. and Rossotti, M.A. and Gonzalez-Sapienza, G. and Ploegh, H.L.
Nature Biomedical Engineering 14 June 2021 (In Press)

Longitudinal single-cell dynamics of chromatin accessibility and mitochondrial mutations in chronic lymphocytic leukemia mirror disease history.
Penter, L. and Gohil, S.H. and Lareau, C. and Ludwig, L.S. and Parry, E.M. and Huang, T. and Li, S. and Zhang, W. and Livitz, D. and Leshchiner, I. and Parida, L. and Getz, G. and Rassenti, L.Z. and Kipps, T.J. and Brown, J.R. and Davids, M.S. and Neuberg, D.S. and Livak, K.J. and Sankaran, V.G. and Wu, C.J.
Cancer Discovery 10 June 2021 (In Press)

Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript.
Wahlster, L. and Verboon, J.M. and Ludwig, L.S. and Black, S.C. and Luo, W. and Garg, K. and Voit, R.A. and Collins, R.L. and Garimella, K. and Costello, M. and Chao, K.R. and Goodrich, J.K. and DiTroia, S.P. and O’Donnell-Luria, A. and Talkowski, M.E. and Michelson, A.D. and Cantor, A.B. and Sankaran, V.G.
Journal of Experimental Medicine 218 (6): e20210444. 7 June 2021

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Mimitou, E.P. and Lareau, C.A. and Chen, K.Y. and Zorzetto-Fernandes, A.L. and Hao, Y. and Takeshima, Y. and Luo, W. and Huang, T.S. and Yeung, B.Z. and Papalexi, E. and Thakore, P.I. and Kibayashi, T. and Wing, J.B. and Hata, M. and Satija, R. and Nazor, K.L. and Sakaguchi, S. and Ludwig, L.S. and Sankaran, V.G. and Regev, A. and Smibert, P.
Nature Biotechnology 3 June 2021 (In Press)

Skin-resident innate lymphoid cells converge on a pathogenic effector state.
Bielecki, P. and Riesenfeld, S.J. and Hütter, J.C. and Torlai Triglia, E. and Kowalczyk, M.S. and Ricardo-Gonzalez, R.R. and Lian, M. and Amezcua Vesely, M.C. and Kroehling, L. and Xu, H. and Slyper, M. and Muus, C. and Ludwig, L.S. and Christian, E. and Tao, L. and Kedaigle, A.J. and Steach, H.R. and York, A.G. and Skadow, M.H. and Yaghoubi, P. and Dionne, D. and Jarret, A. and McGee, H.M. and Porter, C.B.M. and Licona-Limón, P. and Bailis, W. and Jackson, R. and Gagliani, N. and Gasteiger, G. and Locksley, R.M. and Regev, A. and Flavell, R.A.
Nature 592 (7852): 128-132. 1 April 2021

Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Lareau, C.A. and Ludwig, L.S. and Muus, C. and Gohil, S.H. and Zhao, T. and Chiang, Z. and Pelka, K. and Verboon, J.M. and Luo, W. and Christian, E. and Rosebrock, D. and Getz, G. and Boland, G.M. and Chen, F. and Buenrostro, J.D. and Hacohen, N. and Wu, C.J. and Aryee, M.J. and Regev, A. and Sankaran, V.G.
Nature Biotechnology 39 (4): 451-461. April 2021

Mitochondrial variant enrichment from high-throughput single-cell RNA-seq resolves clonal populations.
Miller, T.E. and Lareau, C.A. and Verga, J.A. and Ssozi, D. and Ludwig, L.S. and El Farran, C. and Griffin, G.K. and Lane, A.A. and Bernstein, B.E. and Sankaran, V.G. and van Galen, P.
bioRxiv : 2021.03.08.434450. 9 March 2021

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Muus, C. and Luecken, M.D. and Eraslan, G. and Sikkema, L. and Waghray, A. and Heimberg, G. and Kobayashi, Y. and Vaishnav, E.D. and Subramanian, A. and Smillie, C. and Jagadeesh, K.A. and Duong, E.T. and Fiskin, E. and Triglia, E.T. and Ansari, M. and Cai, P. and Lin, B. and Buchanan, J. and Chen, S. and Shu, J. and Haber, A.L. and Chung, H. and Montoro, D.T. and Adams, T. and Aliee, H. and Allon, S.J. and Andrusivova, Z. and Angelidis, I. and Ashenberg, O. and Bassler, K. and Bécavin, C. and Benhar, I. and Bergenstråhle, J. and Bergenstråhle, L. and Bolt, L. and Braun, E. and Bui, L.T. and Callori, S. and Chaffin, M. and Chichelnitskiy, E. and Chiou, J. and Conlon, T.M. and Cuoco, M.S. and Cuomo, A.S.E. and Deprez, M. and Duclos, G. and Fine, D. and Fischer, D.S. and Ghazanfar, S. and Gillich, A. and Giotti, B. and Gould, J. and Guo, M. and Gutierrez, A.J. and Habermann, A.C. and Harvey, T. and He, P. and Hou, X. and Hu, L. and Hu, Y. and Jaiswal, A. and Ji, L. and Jiang, P. and Kapellos, T.S. and Kuo, C.S. and Larsson, L. and Leney-Greene, M.A. and Lim, K. and Litviňuková, M. and Ludwig, L.S. and Lukassen, S. and Luo, W. and Maatz, H. and Madissoon, E. and Mamanova, L. and Manakongtreecheep, K. and Leroy, S. and Mayr, C.H. and Mbano, I.M. and McAdams, A.M. and Nabhan, A.N. and Nyquist, S.K. and Penland, L. and Poirion, O.B. and Poli, S. and Qi, C.C. and Queen, R. and Reichart, D. and Rosas, I. and Schupp, J.C. and Shea, C.V. and Shi, X. and Sinha, R. and Sit, R.V. and Slowikowski, K. and Slyper, M. and Smith, N.P. and Sountoulidis, A. and Strunz, M. and Sullivan, T.B. and Sun, D. and Talavera-López, C. and Tan, P. and Tantivit, J. and Travaglini, K.J. and Tucker, N.R. and Vernon, K.A. and Wadsworth, M.H. and Waldman, J. and Wang, X. and Xu, K. and Yan, W. and Zhao, W. and Ziegler, C.G.K.
Nature Medicine 27 (3): 546-559. 2 March 2021

2020

Purifying selection against pathogenic mitochondrial DNA in human T cells.
Walker, M.A. and Lareau, C.A. and Ludwig, L.S. and Karaa, A. and Sankaran, V.G. and Regev, A. and Mootha, V.K.
New England Journal of Medicine 383 (16): 1556-1563. 15 October 2020

Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features.
Ray, J.P. and de Boer, C.G. and Fulco, C.P. and Lareau, C.A. and Kanai, M. and Ulirsch, J.C. and Tewhey, R. and Ludwig, L.S. and Reilly, S.K. and Bergman, D.T. and Engreitz, J.M. and Issner, R. and Finucane, H.K. and Lander, E.S. and Regev, A. and Hacohen, N.
Nature Communications 11 (1): 1237. 6 March 2020

2019

Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking.
Lareau, C.A. and Ludwig, L.S. and Sankaran, V.G.
Blood Advances 3 (24): 4161-4165. 23 December 2019

Transcriptional states and chromatin accessibility underlying human erythropoiesis.
Ludwig, L.S. and Lareau, C.A. and Bao, E.L. and Nandakumar, S.K. and Muus, C. and Ulirsch, J.C. and Chowdhary, K. and Buenrostro, J.D. and Mohandas, N. and An, X. and Aryee, M.J. and Regev, A. and Sankaran, V.G.
Cell Reports 27 (11): 3228-3240. 11 June 2019

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
Nandakumar, S.K. and McFarland, S.K. and Mateyka, L.M. and Lareau, C.A. and Ulirsch, J.C. and Ludwig, L.S. and Agarwal, G. and Engreitz, J.M. and Przychodzen, B. and McConkey, M. and Cowley, G.S. and Doench, J.G. and Maciejewski, J.P. and Ebert, B.L. and Root, D.E. and Sankaran, V.G.
eLife 8 : e44080. 9 May 2019

Impaired human hematopoiesis due to a cryptic intronic splicing mutation.
Abdulhay, N.J. and Fiorini, C. and Verboon, J.M. and Ludwig, L.S. and Ulirsch, J.C. and Zieger, B. and Lareau, C.A. and Mi, X. and Roy, A. and Obeng, E.A. and Erlacher, M. and Gupta, N. and Gabriel, S.B. and Ebert, B.L. and Niemeyer, C.M. and Khoriaty, R.N. and Ancliff, P. and Gazda, H.T. and Wlodarski, M.W. and Sankaran, V.G.
Journal of Experimental Medicine 216 (5): 1050-1060. 6 May 2019

Interrogation of human hematopoiesis at single-cell and single-variant resolution.
Ulirsch, J.C. and Lareau, C.A. and Bao, E.L. and Ludwig, L.S. and Guo, M.H. and Benner, C. and Satpathy, A.T. and Kartha, V.K. and Salem, R.M. and Hirschhorn, J.N. and Finucane, H.K. and Aryee, M.J. and Buenrostro, J.D. and Sankaran, V.G.
Nature Genetics 51 (4): 683-693. April 2019

Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics.
Ludwig, L.S. and Lareau, C.A. and Ulirsch, J.C. and Christian, E. and Muus, C. and Li, L.H. and Pelka, K. and Ge, W. and Oren, Y. and Brack, A. and Law, T. and Rodman, C. and Chen, J.H. and Boland, G.M. and Hacohen, N. and Rozenblatt-Rosen, O. and Aryee, M.J. and Buenrostro, J.D. and Regev, A. and Sankaran, V.G.
Cell 176 (6): 1325-1339. 7 March 2019

2018

The genetic landscape of diamond-blackfan anemia.
Ulirsch, J.C. and Verboon, J.M. and Kazerounian, S. and Guo, M.H. and Yuan, D. and Ludwig, L.S. and Handsaker, R.E. and Abdulhay, N.J. and Fiorini, C. and Genovese, G. and Lim, E.T. and Cheng, A. and Cummings, B.B. and Chao, K.R. and Beggs, A.H. and Genetti, C.A. and Sieff, C.A. and Newburger, P.E. and Niewiadomska, E. and Matysiak, M. and Vlachos, A. and Lipton, J.M. and Atsidaftos, E. and Glader, B. and Narla, A. and Gleizes, P.E. and O'Donohue, M.F. and Montel-Lehry, N. and Amor, D.J. and McCarroll, S.A. and O'Donnell-Luria, A.H. and Gupta, N. and Gabriel, S.B. and MacArthur, D.G. and Lander, E.S. and Lek, M. and Da Costa, L. and Nathan, D.G. and Korostelev, A.A. and Do, R. and Sankaran, V.G. and Gazda, H.T.
American Journal of Human Genetics 103 (6): 930-947. 6 December 2018

Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis.
Khajuria, R.K. and Munschauer, M. and Ulirsch, J.C. and Fiorini, C. and Ludwig, L.S. and McFarland, S.K. and Abdulhay, N.J. and Specht, H. and Keshishian, H. and Mani, D.R. and Jovanovic, M. and Ellis, S.R. and Fulco, C.P. and Engreitz, J.M. and Schütz, S. and Lian, J. and Gripp, K.W. and Weinberg, O.K. and Pinkus, G.S. and Gehrke, L. and Regev, A. and Lander, E.S. and Gazda, H.T. and Lee, W.Y. and Panse, V.G. and Carr, S.A. and Sankaran, V.G.
Cell 173 (1): 90-103. 22 March 2018

2017

Confounding in ex vivo models of Diamond-Blackfan anemia.
Ulirsch, J.C. and Lareau, C. and Ludwig, L.S. and Mohandas, N. and Nathan, D.G. and Sankaran, V.G.
Blood 130 (9): 1165-1168. 31 August 2017

2016

Emerging cellular and gene therapies for congenital anemias.
Ludwig, L.S. and Khajuria, R.K. and Sankaran, V.G.
American Journal of Medical Genetics C 172C (4): 332-348. 12 December 2016

Einfluss genetischer Varianten auf die humane Erythropoese [Influence of genetic variants on human erythropoiesis].
Ludwig, L.S.
BIOspektrum 22 (7): 768-769. November 2016

Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.
Wakabayashi, A. and Ulirsch, J.C. and Ludwig, L.S. and Fiorini, C. and Yasuda, M. and Choudhuri, A. and McDonel, P. and Zon, L.I. and Sankaran, V.G.
Proceedings of the National Academy of Sciences of the United States of America 113 (16): 4434-4439. 19 April 2016

Targeted application of human genetic variation can improve red blood cell production from stem cells.
Giani, F.C. and Fiorini, C. and Wakabayashi, A. and Ludwig, L.S. and Salem, R.M. and Jobaliya, C.D. and Regan, S.N. and Ulirsch, J.C. and Liang, G. and Steinberg-Shemer, O. and Guo, M.H. and Esko, T. and Tong, W. and Brugnara, C. and Hirschhorn, J.N. and Weiss, M.J. and Zon, L.I. and Chou, S.T. and French, D.L. and Musunuru, K. and Sankaran, V.G.
Cell Stem Cell 18 (1): 73-78. 7 January 2016

2015

Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
Ludwig, L.S. and Cho, H. and Wakabayashi, A. and Eng, J.C. and Ulirsch, J.C. and Fleming, M.D. and Lodish, H.F. and Sankaran, V.G.
American Journal of Hematology 90 (5): 386-91. May 2015

X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation.
Sankaran, V.G. and Ulirsch, J.C. and Tchaikovskii, V. and Ludwig, L.S. and Wakabayashi, A. and Kadirvel, S. and Lindsley, R.C. and Bejar, R. and Shi, J. and Lovitch, S.B. and Bishop, D.F. and Steensma, D.P.
Journal of Clinical Investigation 125 (4): 1665-1669. 1 April 2015

2014

Altered translation of GATA1 in Diamond-Blackfan anemia.
Ludwig, L.S. and Gazda, H.T. and Eng, J.C. and Eichhorn, S.W. and Thiru, P. and Ghazvinian, R. and George, T.I. and Gotlib, J.R. and Beggs, A.H. and Sieff, C.A. and Lodish, H.F. and Lander, E.S. and Sankaran, V.G.
Nature Medicine 20 (7): 748-753. July 2014

2012

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.
Sankaran, V.G. and Ludwig, L.S. and Sicinska, E. and Xu, J. and Bauer, D.E. and Eng, J.C. and Patterson, H.C. and Metcalf, R.A. and Natkunam, Y. and Orkin, S.H. and Sicinski, P. and Lander, E.S. and Lodish, H.F.
Genes & Development 26 (18): 2075-2087. 15 September 2012

2010

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells.
Polansky, J.K. and Schreiber, L. and Thelemann, C. and Ludwig, L. and Krüger, M. and Baumgrass, R. and Cording, S. and Floess, S. and Hamann, A. and Huehn, J.
Journal of Molecular Medicine 88 (10): 1029-1040. October 2010

This list was generated on Fri Sep 17 02:19:59 2021 CEST.
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