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Quantitative spectroscopy of single molecule interaction times.
Boltz, H.H. and Sirbu, A. and Stelzer, N. and Lohse, M.J. and Schütte, C. and Annibale, P.
Optics Letters 46 (7): 1538-1541. 1 April 2021

Atypical antipsychotics and metabolic syndrome: from molecular mechanisms to clinical differences.
Carli, M. and Kolachalam, S. and Longoni, B. and Pintaudi, A. and Baldini, M. and Aringhieri, S. and Fasciani, I. and Annibale, P. and Maggio, R. and Scarselli, M.
Pharmaceuticals 14 (3): 238. 8 March 2021

Determination of G-protein-coupled receptor oligomerization by molecular brightness analyses in single cells.
Işbilir, A. and Serfling, R. and Möller, J. and Thomas, R. and De Faveri, C. and Zabel, U. and Scarselli, M. and Beck-Sickinger, A.G. and Bock, A. and Coin, I. and Lohse, M.J. and Annibale, P.
Nature Protocols 16 (3): 1419-1451. March 2021

Allosteric coupling and biased agonism in G protein-coupled receptors.
Bock, A. and Bermudez, M.
FEBS Journal 23 February 2021 (In Press)

Structural and functional characterization of allatostatin receptor type-C of Thaumetopoea pityocampa, a potential target for next-generation pest control agents.
Shahraki, A. and Işbilir, A. and Dogan, B. and Lohse, M.J. and Durdagi, S. and Birgul-Iyison, N.
Journal of Chemical Information and Modeling 61 (2): 715-728. 22 February 2021

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors.
Thibado, J. and Tano, J.Y. and Lee, J. and Salas-Estrada, L. and Provasi, D. and Strauss, A. and Lamim Ribeiro, J.M. and Xiang, G. and Broichhagen, J. and Filizola, M. and Lohse, M. and Levitz, J.
bioRxiv : 2021.02.04.429701. 6 February 2021


Pharmacological characterization of the stick insect Carausius morosus allatostatin-C receptor with its endogenous agonist.
Işbilir, A. and Duan Sahbaz, B. and Tuncgenc, G. and Bünemann, M. and Lohse, M.J. and Birgül-Iyison, N.
ACS Omega 5 (50): 32183-32194. 22 December 2020

The role of orthosteric building blocks of bitopic ligands for muscarinic M1 receptors.
Volpato, D. and Kauk, M. and Messerer, R. and Bermudez, M. and Wolber, G. and Bock, A. and Hoffmann, C. and Holzgrabe, U.
ACS Omega 5 (49): 31706-31715. 15 December 2020

Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists.
Işbilir, A. and Möller, J. and Arimont, M. and Bobkov, V. and Perpiñá-Viciano, C. and Hoffmann, C. and Inoue, A. and Heukers, R. and de Graaf, C. and Smit, M.J. and Annibale, P. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 117 (46): 29144-29154. 17 November 2020

Ligand-specific allosteric coupling controls G-protein-coupled receptor signaling.
Holze, J. and Bermudez, M. and Pfeil, E.M. and Kauk, M. and Bödefeld, T. and Irmen, M. and Matera, C. and Dallanoce, C. and De Amici, M. and Holzgrabe, U. and König, G.M. and Tränkle, C. and Wolber, G. and Schrage, R. and Mohr, K. and Hoffmann, C. and Kostenis, E. and Bock, A.
ACS Pharmacology & Translational Science 3 (5): 859-867. 9 October 2020

Optical mapping of cAMP signaling at the nanometer scale.
Bock, A. and Annibale, P. and Konrad, C. and Hannawacker, A. and Anton, S.E. and Maiellaro, I. and Zabel, U. and Sivaramakrishnan, S. and Falcke, M. and Lohse, M.J.
Cell 182 (6): 1519-1530. 17 September 2020

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors.
Möller, J. and Isbilir, A. and Sungkaworn, T. and Osberg, B. and Karathanasis, C. and Sunkara, V. and Grushevskyi, E.O. and Bock, A. and Annibale, P. and Heilemann, M. and Schütte, C. and Lohse, M.J.
Nature Chemical Biology 16 (9): 946-954. September 2020

Establishing a sensitive fluorescence-based quantification method for cyclic nucleotides.
Gruteser, N. and Kohlhas, V. and Balfanz, S. and Franzen, A. and Günther, A. and Offenhäusser, A. and Müller, F. and Nikolaev, V. and Lohse, M.J. and Baumann, A.
BMC Biotechnology 20 (1): 47. 27 August 2020

Kinetic analysis of the early signaling steps of the human chemokine receptor CXCR4.
Perpina-Viciano, C. and Isbilir, A. and Zarca, A. and Caspar, B. and Kilpatrick, L.E. and Hill, S.J. and Smit, M.J. and Lohse, M.J. and Hoffmann, C.
Molecular Pharmacology 98 (2): 72-87. August 2020

Unmasking features of the auto-epitope essential for β(1)-adrenoceptor activation by autoantibodies in chronic heart failure.
Wölfel, A. and Sättele, M. and Zechmeister, C. and Nikolaev, V.O. and Lohse, M.J. and Boege, F. and Jahns, R. and Boivin-Jahns, V.
ESC Heart Failure 7 (4): 1830-1841. August 2020

Structural and functional characterization of allatostatin receptor type-C of Thaumetopoea pityocampa revealed the importance of Q271(6.55) residue in G protein-dependent activation pathway.
Shahraki, A. and Isbilir, A. and Dogan, B. and Lohse, M.J. and Durdagi, S. and Birgul-Iyison, N.
bioRxiv : 2020.07.01.174037. 2 July 2020

Development of a conformational histamine H(3) receptor biosensor for the synchronous screening of agonists and inverse agonists.
Schihada, H. and Ma, X. and Zabel, U. and Vischer, H.F. and Schulte, G. and Leurs, R. and Pockes, S. and Lohse, M.J.
ACS Sensors 5 (6): 1734-1742. 26 June 2020

Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques.
Uroda, T. and Chillón, I. and Annibale, P. and Teulon, J.M. and Pessey, O. and Karuppasamy, M. and Pellequer, J.L. and Marcia, M.
Nature Protocols 15 (6): 2107-2139. June 2020

Linescan microscopy data to extract diffusion coefficient of a fluorescent species using a commercial confocal microscope.
Bathe-Peters, M. and Gmach, P. and Annibale, P. and Lohse, M.J.
Data in Brief 29 : 105063. April 2020

Spatial heterogeneity in molecular brightness.
Annibale, P. and Lohse, M.J.
Nature Methods 17 (3): 273-275. March 2020

Differential signaling profiles of MC4R mutations with three different ligands.
Paisdzior, S. and Dimitriou, I.M. and Schöpe, P.C. and Annibale, P. and Scheerer, P. and Krude, H. and Lohse, M.J. and Biebermann, H. and Kühnen, P.
International Journal of Molecular Sciences 21 (4): 1224. 12 February 2020

Hypnotika und Sedativa.
Lohse, M.J.
In: Arzneiverordnungs-Report 2020 : Aktuelle Daten, Kosten, Trends und Kommentare. Springer, Berlin, Heidelberg, 571-582. ISBN 978-3-662-62167-7 2020

Lohse, M.J.
In: Arzneiverordnungs-Report 2020 : Aktuelle Daten, Kosten, Trends und Kommentare. Springer, Berlin, Heidelberg, 733-758. ISBN 978-3-662-62168-4 2020

Lohse, M.J.
In: Arzneiverordnungs-Report 2020 : Aktuelle Daten, Kosten, Trends und Kommentare. Springer, Berlin, Heidelberg, 781-814. ISBN 978-3-662-62168-4 2020


Context-dependent signaling of CXC chemokine receptor 4 and atypical chemokine receptor 3.
Heuninck, J. and Perpina Viciano, C. and Işbilir, A. and Caspar, B. and Capoferri, D. and Briddon, S.J. and Durroux, T. and Hill, S.J. and Lohse, M.J. and Milligan, G. and Pin, J.P. and Hoffmann, C.
Molecular Pharmacology 96 (6): 778-793. December 2019

Vibrational spectroscopy as a powerful tool for follow-up immunoadsorption therapy treatment of dilated cardiomyopathy - a case report.
Huang, J. and Ramoji, A. and Guo, S. and Bocklitz, T. and Boivin-Jahns, V. and Möller, J. and Kiehntopf, M. and Noutsias, M. and Popp, J. and Neugebauer, U.
Analyst 145 (2): 486-496. 15 November 2019

Conserved pseudoknots in lncRNA MEG3 are essential for stimulation of the p53 pathway.
Uroda, T. and Anastasakou, E. and Rossi, A. and Teulon, J.M. and Pellequer, J.L. and Annibale, P. and Pessey, O. and Inga, A. and Chillón, I. and Marcia, M.
Molecular Cell 75 (5): 982-995. 5 September 2019

Quantitative single-residue bioorthogonal labeling of G protein-coupled receptors in live cells.
Serfling, R. and Seidel, L. and Bock, A. and Lohse, M.J. and Annibale, P. and Coin, I.
ACS Chemical Biology 14 (6): 1141-1149. 21 June 2019

Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement.
Grushevskyi, E.O. and Kukaj, T. and Schmauder, R. and Bock, A. and Zabel, U. and Schwabe, T. and Benndorf, K. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 116 (20): 10150-10155. 14 May 2019

Does divergent binding pocket closure drive ligand bias for class A GPCRs?
Bermudez, M. and Bock, A.
Trends in Pharmacological Sciences 40 (4): 236-239. April 2019

All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics.
Bathe-Peters, M. and Gmach, P. and Annibale, P. and Lohse, M.J.
In: Imaging and Applied Optics Congress 2019 (COSI, IS, MATH, pcAOP), 24-27 Jun 2019, Munich, Germany. 2019


A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety.
Hommers, L.G. and Richter, J. and Yang, Y. and Raab, A. and Baumann, C. and Lang, K. and Schiele, M.A. and Weber, H. and Wittmann, A. and Wolf, C. and Alpers, G.W. and Arolt, V. and Domschke, K. and Fehm, L. and Fydrich, T. and Gerlach, A. and Gloster, A.T. and Hamm, A.O. and Helbig-Lang, S. and Kircher, T. and Lang, T. and Pané-Farré, C.A. and Pauli, P. and Pfleiderer, B. and Reif, A. and Romanos, M. and Straube, B. and Ströhle, A. and Wittchen, H.U. and Frantz, S. and Ertl, G. and Lohse, M.J. and Lueken, U. and Deckert, J.
Translational Psychiatry 8 (1): 226. 19 October 2018

A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics.
Schihada, H. and Vandenabeele, S. and Zabel, U. and Frank, M. and Lohse, M.J. and Maiellaro, I.
Communications Biology 1 : 105. 7 August 2018

Allosteric modulators targeting CNS muscarinic receptors.
Bock, A. and Schrage, R. and Mohr, K.
Neuropharmacology 136 (Part C): 427-437. 1 July 2018

A panoramic view on GPCRs: the 1st Berlin Symposium for Interdisciplinary GPCR research.
Bock, A. and Bermudez, M.
Naunyn-Schmiedeberg's Archives of Pharmacology 391 (7): 769-771. July 2018

Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations.
Meral, D. and Provasi, D. and Prada-Gracia, D. and Möller, J. and Marino, K. and Lohse, M.J. and Filizola, M.
Scientific Reports 8 (1): 7705. 16 May 2018

Increased fear learning, spatial learning as well as neophobia in Rgs2(-/-) mice.
Raab, A. and Popp, S. and Lesch, K.P. and Lohse, M.J. and Fischer, M. and Deckert, J. and Hommers, L.
Genes Brain and Behavior 17 (4): e12420. April 2018

All-optical microscope autofocus based on an electrically tunable lens and a totally internally reflected IR laser.
Bathe-Peters, M. and Annibale, P. and Lohse, M.J.
Optics Express 26 (3): 2359-2368. 5 February 2018

Related GPCRs couple differently to G(s): preassociation between G protein and 5-HT(7) serotonin receptor reveals movement of Gα(s) upon receptor activation.
Andressen, K.W. and Ulsund, A.H. and Krobert, K.A. and Lohse, M.J. and Buenemann, M. and Levy, F.O.
FASEB Journal 32 (2): 1059-1069. 5 February 2018


Visualization of class A GPCR oligomerization by image-based fluorescence fluctuation spectroscopy.
Isbilir, A. and Moeller, J. and Bock, A. and Zabel, U. and Annibale, P. and Lohse, M.J.
bioRxiv : 240903. 29 December 2017

Evolutionary action and structural basis of the allosteric switch controlling β(2)AR functional selectivity.
Schönegge, A.M. and Gallion, J. and Picard, L.P. and Wilkins, A.D. and Le Gouill, C. and Audet, M. and Stallaert, W. and Lohse, M.J. and Kimmel, M. and Lichtarge, O. and Bouvier, M.
Nature Communications 8 (1): 2169. 18 December 2017

Single-molecule imaging reveals receptor-G protein interactions at cell surface hot spots.
Sungkaworn, T. and Jobin, M.L. and Burnecki, K. and Weron, A. and Lohse, M.J. and Calebiro, D.
Nature 550 (7677): 543-547. 26 October 2017

Mapping the dynamics of the glucocorticoid receptor within the nuclear landscape.
Stortz, M. and Presman, D.M. and Bruno, L. and Annibale, P. and Dansey, M.V. and Burton, G. and Gratton, E. and Pecci, A. and Levi, V.
Scientific Reports 7 (1): 6219. 24 July 2017

Ligand-specific restriction of extracellular conformational dynamics constrains signaling of the M(2) muscarinic receptor.
Bermudez, M. and Bock, A. and Krebs, F. and Holzgrabe, U. and Mohr, K. and Lohse, M.J. and Wolber, G.
ACS Chemical Biology 12 (7): 1743-1748. 21 July 2017

Is signaling specificity encoded in arrestin conformation?
Hoffmann, C. and Lohse, M.J. and Luttrell, L.M.
In: The Structural Basis of Arrestin Functions. Springer, Cham, Switzerland, 235-253. ISBN 978-3-319-57552-0 25 May 2017

Was ist in der Medizin moeglich: Neue Therapien.
Lohse, M.
In: Medizin 4.0 - Zur Zukunft der digitalisierten Welt. IV. Interdisziplinaerer Kongress Berlin 2016 mit der Heinz Nixdorf-Stiftung - gemeinsam mit der Charite - Universitaetsmedizin Berlin, 1-2 June 2016, Berlin, Germany. 2017

This list was generated on Sat Apr 17 02:19:16 2021 CEST.
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