Browse by Research Team

2020

Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in wildtype and cloche/npas4l mutant zebrafish embryos.
McGarvey, A.C. and Kopp, W. and Vučićević, D. and Kempfer, R. and Mattonet, K. and Hirsekorn, A. and Bilić, I. and Trinks, A. and Merks, A.M. and Panáková, D. and Pombo, A. and Akalin, A. and Junker, J.P. and Stainier, D.Y.R. and Garfield, D. and Ohler, U. and Lacadie, S.A.
bioRxiv : 2020.06.26.173377. 26 June 2020

2018

Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
Nature Communications 9 (1): 4472. 26 October 2018

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. and Ofenbauer, A. and Bulut, S.I. and Uyar, B. and Baytek, G. and Sommermeier, A. and Seelk, S. and He, M. and Hirsekorn, A. and Vucicevic, D. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

Redundant regulation.
Lacadie, S.A. and Ohler, U.
Nature Ecology & Evolution 2 (3): 418-419. March 2018

2017

Determinants of transcription initiation directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
bioRxiv : 224642. 24 November 2017

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
Kolundzic, E. and Ofenbauer, A. and Uyar, B. and Sommermeier, A. and Seelk, S. and He, M. and Baytek, G. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
bioRxiv : 185116. 6 September 2017

2015

Human promoters are intrinsically directional.
Duttke, S.H.C. and Lacadie, S.A. and Ibrahim, M.M. and Glass, C.K. and Corcoran, D.L. and Benner, C. and Heinz, S. and Kadonaga, J.T. and Ohler, U.
Molecular Cell 57 (4): 674-684. 19 February 2015

JAMM: a peak finder for joint analysis of NGS replicates.
Ibrahim, M.M. and Lacadie, S.A. and Ohler, U.
Bioinformatics 31 (1): 48-55. 1 January 2015

2013

NextGen speaks.
Lacadie, S.A.
Science 340 (6128): 29. April 2013

2012

The transcriptional landscape of hematopoietic stem cell ontogeny.
McKinney-Freeman, S. and Cahan, P. and Li, H. and Lacadie, S.A. and Huang, H.T. and Curran, M. and Loewer, S. and Naveiras, O. and Kathrein, K.L. and Konantz, M. and Langdon, E.M. and Lengerke, C. and Zon, L.I. and Collins, J.J. and Daley, G.Q.
Cell Stem Cell 11 (5): 701-714. 2 November 2012

Small molecule screening in zebrafish: swimming in potential drug therapies.
Tamplin, O.J. and White, R.M. and Jing, L. and Kaufman, C.K. and Lacadie, S.A. and Li, P. and Taylor, A.M. and Zon, L.I.
Wiley Interdisciplinary Reviews: Developmental Biology 1 (3): 459-468. May 2012

2011

The ERGonomics of hematopoietic stem cell self-renewal.
Lacadie, S.A. and Zon, L.I.
Genes & Development 25 (4): 289-293. 15 February 2011

2006

A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional.
Tardiff, D.F. and Lacadie, S.A. and Rosbash, M.
Molecular Cell 24 (6): 917-929. 28 December 2006

In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants.
Lacadie, S.A. and Tardiff, D.F. and Kadener, S. and Rosbash, M.
Genes & Development 20 (15): 2055-2066. 1 August 2006

2005

Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast.
Lacadie, S.A. and Rosbash, M.
Molecular Cell 19 (1): 65-75. 1 July 2005

2004

Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes.
Abruzzi, K.C. and Lacadie, S. and Rosbash, M.
EMBO Journal 23 (13): 2620-2631. 7 July 2004