Browse by Research Team

Article

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.
Wegener, E., Oeckinghaus, A., Papadopoulou, N., Lavitas, L., Schmidt-Supprian, M., Ferch, U., Mak, T.W., Ruland, J., Heissmeyer, V. and Krappmann, D.
Molecular Cell 23 (1): 13-23. 7 July 2006

Viral targeting of the interferon-beta-inducing Traf family member-associated NF-kappaB activator (TANK)-binding kinase-1.
Unterstab, G., Ludwig, S., Anton, A., Planz, O., Dauber, B., Krappmann, D., Heins, G., Ehrhardt, C. and Wolff, T.
Proceedings of the National Academy of Sciences of the United States of America 102 (38): 13640-13645. 9 September 2005

Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.
Broemer, M., Krappmann, D. and Scheidereit, C.
Oncogene 23 (31): 5378-5386. 8 July 2004

The IκB kinase complex and NF-κB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1.
Krappmann, D., Wegener, E., Sunami, Y., Esen, M., Thiel, A., Mordmueller, B. and Scheidereit, C.
Molecular and Cellular Biology 24 (14): 6488-6500. 1 July 2004

Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappaB signaling.
Scharschmidt, E., Wegener, E., Heissmeyer, V., Rao, A. and Krappmann, D.
Molecular and Cellular Biology 24 (9): 3860-3873. 1 May 2004

Lymphotoxin and lipopolysaccharide induce NF-κB-p52 generation by a co-translational mechanism.
Mordmueller, B., Krappmann, D., Esen, M., Wegener, E. and Scheidereit, C.
EMBO Reports 4 (1): 82-87. 1 January 2003

Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M., Lemke, P., Anagnostopoulos, I., Hacker, C., Krappmann, D., Mathas, S., Doerken, B., Zenke, M., Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196 (5): 605-617. 2 September 2002

Purification and characterization of the human Elongator complex.
Hawkes, N.A., Otero, G., Winkler, G.S., Marshall, N., Dahmus, M.E., Krappmann, D., Scheidereit, C., Thomas, C.L., Schiavo, G., Erdjument-Bromage, H., Tempst, P. and Svejstrup, J.Q.
Journal of Biological Chemistry 277 (4): 3047-3052. 1 January 2002

Book Section

NF-κB pathway.
Scheidereit, C. and Krappmann, D.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1286-1292. ISBN 3-540-44244-8 2006

Review

A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways.
Krappmann, D. and Scheidereit, C.
EMBO Reports 6 (4): 321-326. 1 January 2005