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Integrated left ventricular multi-omics landscape of human cardiometabolic HFpEF.
Capone, Federico 
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Cardiovascular Research 122
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May 2026
Supplementation with short-chain fatty acids and a prebiotic improves clinical outcome in Parkinson’s disease: a randomized double-blind prospective study.
Hegelmaier, Tobias, Duscha, Alexander, Desel, Christiane, Fuchs, Sabrina, Shapira, Michal, Amidror, Sivan, Shan, Qihao, Stangl, Gabriele I., Hirche, Frank, Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299, Maifeld, András ORCID: https://orcid.org/0000-0001-8756-747X, Würtele, Lisa-Marie, Peplinski, Jana, Jauk, Diana, Naim, Gitali, Shidlovsky, Nuphar, Cohen, Adva, Bennet, Yifat, Paschold, Lisa, Dumitru, Claudia A., Obermüller-Jevic, Ute, Hustvedt, Svein-Olaf, Timmesfeld, Nina, Gold, Ralf, Zapf, Antonia, Binder, Mascha, Sandalcioglu, Ibrahim E., Mostaghim, Sanaz, Przuntek, Horst, Segal, Eran, Yissachar, Nissan and Haghikia, Aiden
Scientific Reports 16
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5 January 2026
Extensive folding variability between homologous chromosomes in mammalian cells.
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Molecular Systems Biology 21
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2 July 2025
Extrusion of BMP2+ surface colonocytes promotes stromal remodeling and tissue regeneration.
Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Liu, L., Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, van den Heuvel, J., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Müllerke, S., Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725, de Jonge, H. ORCID: https://orcid.org/0000-0003-2777-4084, Gherardi, E. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 16
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3 May 2025
Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface.
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Cardiovascular Research 121
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April 2025
Novel high-throughput screen identified S100A4 inhibitors for anti-metastatic therapy.
Schöpe, Paul Curtis ORCID: https://orcid.org/0000-0002-5512-8832, Heisterkamp, Nina, Schütz, Devin, Mastrobuoni, Guido ORCID: https://orcid.org/0000-0003-4509-1295, Putzker, Kerstin, Uhrig, Ulrike, Walther, Wolfgang ORCID: https://orcid.org/0000-0003-2360-1370, Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299, Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330, Kobelt, Dennis ORCID: https://orcid.org/0000-0002-9373-0648 and Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X
International Journal of Biological Sciences 21
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2025
Metformin modulates microbiota and improves blood pressure and cardiac remodeling in a rat model of hypertension.
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Acta Physiologica 240
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November 2024
p53 terminates the regenerative fetal-like state after colitis-associated injury.
Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Bayram, Ş. ORCID: https://orcid.org/0009-0009-5245-5473, Wetzel, A., Harnack, C., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Liu, L. ORCID: https://orcid.org/0000-0002-9553-5475, Beccacec, G. ORCID: https://orcid.org/0000-0002-6453-3725, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Monteiro, B.J.E. ORCID: https://orcid.org/0000-0001-9718-2776, Macino, M. ORCID: https://orcid.org/0000-0002-8730-9005, Flores, R.E. ORCID: https://orcid.org/0000-0001-6500-8407, Engelmann, C., Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Schupp, M. ORCID: https://orcid.org/0000-0003-3720-1052, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Science Advances 10
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25 October 2024
Multilayer nanocarrier for the codelivery of interferons: a promising strategy for biocompatible and long-acting antiviral treatment.
Ramos, T.I., Villacis-Aguirre, C.A. ORCID: https://orcid.org/0000-0002-3276-5150, Sandoval, F.S., Martin-Solano, S. ORCID: https://orcid.org/0000-0001-8468-6924, Manrique-Suárez, V., Rodríguez, H. ORCID: https://orcid.org/0000-0001-6910-5685, Santiago-Padilla, L. ORCID: https://orcid.org/0000-0002-0873-7205, Debut, A. ORCID: https://orcid.org/0000-0002-8269-7619, Gómez-Gaete, C., Arias, M.T. ORCID: https://orcid.org/0000-0002-3902-5083, Montesino, R. ORCID: https://orcid.org/0000-0002-4767-7110, Lamazares, E., Cabezas, I. ORCID: https://orcid.org/0000-0001-8118-2579, Hugues, F. ORCID: https://orcid.org/0000-0002-2283-6269, Parra, N.C. ORCID: https://orcid.org/0000-0003-0034-480X, Altamirano, C. ORCID: https://orcid.org/0000-0002-6389-086X, Ramos, O.S. ORCID: https://orcid.org/0000-0002-9744-8674, Santiago-Vispo, N. ORCID: https://orcid.org/0000-0002-4081-3984 and Toledo, J.R.
Pharmaceutics 16
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22 October 2024
Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia.
Mochmann, L.H., Treue, D., Bockmayr, M., Silva, P., Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Jurmeister, P., Liebig, S. ORCID: https://orcid.org/0000-0002-5494-8476, Blau, O., Schleich, K., Splettstoesser, B., Nordmann, T.M., von der Heide, E.K., Isaakidis, K., Schulze, V., Busch, C. ORCID: https://orcid.org/0000-0001-5608-2218, Siddiq, H., Schlee, C., Hester, S., Fransecky, L., Neumann, M., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Klauschen, F. and Baldus, C.D.
Cancer Gene Therapy 31
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September 2024
The effects of hypoxia on the immune-metabolic interplay in liver cancer.
He, Y., Xu, H., Liu, Y., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Vechiatto, C., Schmidt, R. ORCID: https://orcid.org/0000-0003-0012-2799, Yilmaz, E.Y. ORCID: https://orcid.org/0009-0004-1789-6488, Heidemann, L., Schnorr, J. ORCID: https://orcid.org/0000-0002-9819-3060, Metzkow, S., Schellenberger, E. ORCID: https://orcid.org/0000-0003-4096-6865, Häckel, A., Patzak, A. ORCID: https://orcid.org/0000-0002-1088-6875, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644 and Savic, L.J. ORCID: https://orcid.org/0000-0003-2115-6728
Biomolecules 14
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17 August 2024
L-glyceraldehyde inhibits neuroblastoma cell growth via a
multi-modal mechanism on metabolism and Signaling.
Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Kempa, R., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Rayman, L., Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Arlt, B. ORCID: https://orcid.org/0000-0002-6665-4037, Spruessel, A., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Cancers 16
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May 2024
Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.
Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Baumgardt, M., Langner, C., Fischer, M., Maria Adler, J., Bushe, J., Firsching, T.C., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Grobe, J., Hoenzke, K., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Gruber, A.D., Hocke, A.C., Trimpert, J., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
BMJ Open Respiratory Research 11
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29 February 2024
Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Emmenegger, L. ORCID: https://orcid.org/0000-0003-2165-7944, Zappulo, A., Rybak-Wolf, A. ORCID: https://orcid.org/0000-0002-1192-5290, Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Oliveras Martinez, A. ORCID: https://orcid.org/0000-0002-5880-5245, Cerda Jara, C. ORCID: https://orcid.org/0000-0003-1783-5533, Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Hessler, T., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Zinzen, R. ORCID: https://orcid.org/0000-0002-8638-5102, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313 and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Nature Methods 20
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October 2023
Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G. ORCID: https://orcid.org/0000-0002-9094-1423, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Rauch, A. ORCID: https://orcid.org/0000-0002-5152-5830, Chen, C.Y. ORCID: https://orcid.org/0000-0003-1765-7132, N'Diaye, G., Löber, U. ORCID: https://orcid.org/0000-0001-7468-9531, Bartolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Fritsche-Guenther, R. ORCID: https://orcid.org/0000-0002-6965-0226, Rodrigues, A.F. ORCID: https://orcid.org/0000-0002-7219-6896, Yarritu, A. ORCID: https://orcid.org/0000-0002-1724-0559, Zhong, C., Fei, L., Tsvetkov, D. ORCID: https://orcid.org/0000-0002-6472-971X, Todiras, M. ORCID: https://orcid.org/0000-0002-9373-4753, Park, J.K., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, Maifeld, A. ORCID: https://orcid.org/0000-0001-8756-747X, Patzak, A., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Kirwan, J.A. ORCID: https://orcid.org/0000-0002-5423-1651, Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644 and Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364
Cardiovascular Research 119
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May 2023
A comprehensive molecular profiling approach reveals metabolic alterations that steer bone tissue regeneration.
Löffler, J., Noom, A., Ellinghaus, A., Dienelt, A., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Duda, G.N. ORCID: https://orcid.org/0000-0001-7605-3908
Communications Biology 6
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27 March 2023
Advancements in pulsed stable isotope-resolved metabolomics.
Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Handbook of Experimental Pharmacology 277
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3 March 2023
Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.
Côrte-Real, B.F., Hamad, I., Arroyo Hornero, R., Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Roels, J., Van Zeebroeck, L., Dyczko, A., van Gisbergen, M.W., Kurniawan, H., Wagner, A., Yosef, N., Weiss, S.N.Y., Schmetterer, K.G., Schröder, A., Krampert, L., Haase, S., Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Hellings, N., Saeys, Y., Dubois, L.J., Brenner, D., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Hafler, D.A., Stegbauer, J., Linker, R.A., Jantsch, J., Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644 and Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149
Cell Metabolism 35
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7 February 2023
Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla, T. ORCID: https://orcid.org/0000-0001-9527-8061, Gollasch, B., Kuich, P.H.J.L., Klug, L., Rahn, G., Busjahn, A. ORCID: https://orcid.org/0000-0001-9650-6919, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Boschmann, M. ORCID: https://orcid.org/0000-0002-0114-7114, Kirwan, J.A. ORCID: https://orcid.org/0000-0002-5423-1651, Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Frontiers in Molecular Biosciences 9
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21 December 2022
Inflammation in children with chronic kidney disease linked to gut dysbiosis and metabolite imbalance.
Holle, J. ORCID: https://orcid.org/0000-0001-8032-4096, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Löber, U. ORCID: https://orcid.org/0000-0001-7468-9531, Behrens, F. ORCID: https://orcid.org/0000-0002-6841-4192, Bartolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Anandakumar, H. ORCID: https://orcid.org/0009-0000-3326-5126, Wimmer, M. ORCID: https://orcid.org/0009-0004-5793-0249, Vu, D.L., Kuhring, M. ORCID: https://orcid.org/0000-0002-3287-0313, Brüning, U. ORCID: https://orcid.org/0000-0003-0112-4032, Maifeld, A. ORCID: https://orcid.org/0000-0001-8756-747X, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Schumacher, F., Kleuser, B., Bufler, P., Querfeld, U., Kitschke, S., Engler, D., Kuhrt, L.D. ORCID: https://orcid.org/0000-0001-7157-6988, Drechsel, O., Eckardt, K.U., Forslund, S. ORCID: https://orcid.org/0000-0003-4285-6993, Thürmer, A., McParland, V. ORCID: https://orcid.org/0000-0003-0731-3272, Kirwan, J. ORCID: https://orcid.org/0000-0002-5423-1651, Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364 and Mueller, D.
Journal of the American Society of Nephrology 33
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December 2022
Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics.
Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Razzaque, Y.S., Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Fürst, S., Vechiatto, C., Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Frontiers in Molecular Biosciences 9
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12 August 2022
Renal deletion of LRRC8/VRAC channels induces proximal tubulopathy.
López-Cayuqueo, K.I. ORCID: https://orcid.org/0000-0001-8409-7345, Planells-Cases, R. ORCID: https://orcid.org/0000-0002-9841-8434, Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Oliveras, A. ORCID: https://orcid.org/0000-0002-5880-5245, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Bachmann, S. and Jentsch, T.J. ORCID: https://orcid.org/0000-0002-3509-2553
Journal of the American Society of Nephrology 33
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August 2022
HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U. ORCID: https://orcid.org/0000-0002-0782-7751, Milek, M. ORCID: https://orcid.org/0000-0002-0803-8439, Minia, I. ORCID: https://orcid.org/0000-0003-1012-3373, Vieira-Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507, Müller, S., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Hazapis, O.G., Del Giudice, S. ORCID: https://orcid.org/0000-0003-0194-3767, Schwefel, D. ORCID: https://orcid.org/0000-0002-2945-0908, Bley, N., Voigt, F., Chao, J.A. ORCID: https://orcid.org/0000-0002-5895-9156, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Hüttelmaier, S. ORCID: https://orcid.org/0000-0001-9335-4227, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
Nature Communications 13
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18 May 2022
Optimized workflow for on-line derivatization for targeted metabolomics approach by gas chromatography-mass spectrometry.
Fritsche-Guenther, R. ORCID: https://orcid.org/0000-0002-6965-0226, Gloaguen, Y. ORCID: https://orcid.org/0000-0003-0493-8592, Bauer, A., Opialla, T. ORCID: https://orcid.org/0000-0001-9527-8061, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Fleming, C.A., Redmond, H.P. and Kirwan, J.A. ORCID: https://orcid.org/0000-0002-5423-1651
Metabolites 11
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18 December 2021
Salt transiently inhibits mitochondrial energetics in mononuclear phagocytes.
Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Neubert, P., Willebrand, R., Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Bartolomaeus, T., McParland, V. ORCID: https://orcid.org/0000-0003-0731-3272, Swinnen, D. ORCID: https://orcid.org/0000-0003-0082-2226, Geuzens, A. ORCID: https://orcid.org/0000-0001-5928-6953, Maifeld, A. ORCID: https://orcid.org/0000-0001-8756-747X, Krampert, L., Vogl, M., Mähler, A. ORCID: https://orcid.org/0000-0002-3904-5789, Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364, Marko, L. ORCID: https://orcid.org/0000-0003-1888-5575, Tilic, E. ORCID: https://orcid.org/0000-0003-0463-322X, Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Binger, K.J. ORCID: https://orcid.org/0000-0003-1139-3308, Stegbauer, J. ORCID: https://orcid.org/0000-0001-8994-8102, Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149, Jantsch, J., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644
Circulation 144
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13 July 2021
Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect.
Arlt, B. ORCID: https://orcid.org/0000-0002-6665-4037, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Wuenschel, J., Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Journal of Enzyme Inhibition and Medicinal Chemistry 36
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30 June 2021
Maternal angiotensin increases placental leptin in early gestation via an alternative renin-angiotensin system pathway: suggesting a link to preeclampsia.
Nonn, O. ORCID: https://orcid.org/0000-0001-6385-2866, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, El-Heliebi, A., Kroneis, T. ORCID: https://orcid.org/0000-0002-4761-9340, Forstner, D., Desoye, G., Staff, A.C. ORCID: https://orcid.org/0000-0001-9247-5721, Sugulle, M., Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Pecks, U. ORCID: https://orcid.org/0000-0002-0784-1262, Kollmann, M., Stern, C., Cartwright, J.E., Whitley, G.S., Thilaganathan, B. ORCID: https://orcid.org/0000-0002-5531-4301, Wadsack, C., Huppertz, B. ORCID: https://orcid.org/0000-0003-4814-2158, Herse, F. ORCID: https://orcid.org/0000-0002-9305-8134 and Gauster, M. ORCID: https://orcid.org/0000-0003-0386-6857
Hypertension 77
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May 2021
Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy.
Mitra, D., Vega-Rubin-de-Celis, S. ORCID: https://orcid.org/0000-0002-4196-8996, Royla, N., Bernhardt, S., Wilhelm, H., Tarade, N., Poschet, G., Buettner, M., Binenbaum, I., Borgoni, S., Vetter, M., Kantelhardt, E.J., Thomssen, C., Chatziioannou, A., Hell, R., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Müller-Decker, K. and Wiemann, S. ORCID: https://orcid.org/0000-0003-4683-3174
International Journal of Cancer 148
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15 April 2021
Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt, B. ORCID: https://orcid.org/0000-0002-6665-4037, Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Wuenschel, J., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Lodrini, M., Astrahantseff, K., Winkler, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Finkler, S., Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Hundsdoerfer, P., Guergen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Hoffmann, J., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Eggert, A., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
International Journal of Cancer 148
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1 March 2021
Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex.
Weigt, M., Gao, Q. ORCID: https://orcid.org/0000-0002-9930-8499, Ban, H., He, H., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627 and Li, F. ORCID: https://orcid.org/0000-0002-1206-9684
Epigenetics & Chromatin 14
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19 January 2021
Towards a more reliable identification of isomeric metabolites using pattern guided retention validation.
Opialla, T. ORCID: https://orcid.org/0000-0001-9527-8061, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511
Metabolites 10
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12 November 2020
Integrative functional genomics decodes herpes simplex virus 1.
Whisnant, A.W. ORCID: https://orcid.org/0000-0003-2039-2809, Jürges, C.S. ORCID: https://orcid.org/0000-0001-5617-6601, Hennig, T., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Prusty, B. ORCID: https://orcid.org/0000-0001-7051-4670, Rutkowski, A.J., L'hernault, A., Djakovic, L. ORCID: https://orcid.org/0000-0002-9368-9403, Göbel, M., Döring, K., Menegatti, J., Antrobus, R., Matheson, N.J. ORCID: https://orcid.org/0000-0002-3318-1851, Künzig, F.W.H. ORCID: https://orcid.org/0000-0003-3730-3905, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Bielow, C. ORCID: https://orcid.org/0000-0001-5756-3988, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Liang, C. ORCID: https://orcid.org/0000-0002-0305-2522, Dandekar, T. ORCID: https://orcid.org/0000-0003-1886-7625, Zimmer, R., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Grässer, F., Lehner, P.J., Friedel, C.C. ORCID: https://orcid.org/0000-0003-3569-4877, Erhard, F. ORCID: https://orcid.org/0000-0002-3574-6983 and Dölken, L. ORCID: https://orcid.org/0000-0002-4651-3544
Nature Communications 11
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27 April 2020
Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription.
Cossa, G., Roeschert, I., Prinz, F., Baluapuri, A., Silveira Vidal, R., Schülein-Völk, C., Chang, Y.C., Ade, C.P., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Girard, C., Kumar, A., Wortmann, L., Walz, S., Lührmann, R., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Kuster, B., Wolf, E., Mumberg, D. and Eilers, M.
Molecular Cell 77
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19 March 2020
Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism.
Duscha, A., Gisevius, B., Hirschberg, S., Yissachar, N., Stangl, G.I., Eilers, E., Bader, V., Haase, S., Kaisler, J., David, C., Schneider, R., Troisi, R., Zent, D., Hegelmaier, T., Dokalis, N., Gerstein, S., Del Mare-Roumani, S., Amidror, S., Staszewski, O., Poschmann, G., Stühler, K., Hirche, F., Balogh, A. ORCID: https://orcid.org/0000-0001-8756-747X, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Träger, P., Zaiss, M.M., Holm, J.B., Massa, M.G., Nielsen, H.B., Faissner, A., Lukas, C., Gatermann, S.G., Scholz, M., Przuntek, H., Prinz, M., Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Winklhofer, K.F., Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Linker, R.A., Gold, R. and Haghikia, A.
Cell 180
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19 March 2020
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates.
Langer, H.T. ORCID: https://orcid.org/0000-0003-1838-4279, Afzal, S. ORCID: https://orcid.org/0009-0009-5490-6098, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
Scientific Reports 10
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5 February 2020
Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer.
Berndt, N., Egners, A., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Vvedenskaya, O. ORCID: https://orcid.org/0000-0001-7808-269X, Fragoulis, A., Dugourd, A., Bulik, S., Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Bielow, C. ORCID: https://orcid.org/0000-0001-5756-3988, van Gassel, R., Olde Damink, S.W., Erdem, M., Saez-Rodriguez, J., Holzhütter, H.G., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Cramer, T.
British Journal of Cancer 122
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21 January 2020
Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A. ORCID: https://orcid.org/0000-0002-3455-2992, Sengul, T.G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M.H. ORCID: https://orcid.org/0000-0003-0112-9917, Ofenbauer, A. ORCID: https://orcid.org/0000-0003-0379-9105, Gesell-Salazar, M., Balogh, A. ORCID: https://orcid.org/0000-0001-8756-747X, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629, Robbins, C.T., Völker, U., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Nelson, L. and Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172
Scientific Reports 9
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27 December 2019
The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S. ORCID: https://orcid.org/0000-0002-3525-8859, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, He, M., Krause, A. ORCID: https://orcid.org/0000-0001-9515-2477, Vitrinel, B. ORCID: https://orcid.org/0000-0002-5049-6572, Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629
Aging Cell 18
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December 2019
Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi, V. ORCID: https://orcid.org/0000-0001-7538-1520, Peng, S., Klironomos, F., Munschauer, M. ORCID: https://orcid.org/0000-0001-6143-4548, Kastelic, N., Chakraborty, T., Schoeler, K., Derudder, E. ORCID: https://orcid.org/0000-0003-1421-4045, Martella, M., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X, Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Quintanilla-Martinez de Fend, L., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Genes & Development 33
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7 November 2019
WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N., Gloaguen, Y. ORCID: https://orcid.org/0000-0003-0493-8592, Opialla, T. ORCID: https://orcid.org/0000-0001-9527-8061, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Sicard, E., Royer, A.L., Le Bizec, B. ORCID: https://orcid.org/0000-0002-0600-5895, Durand, S., Migné, C., Pétéra, M., Pujos-Guillot, E., Giacomoni, F. ORCID: https://orcid.org/0000-0001-6063-4214, Guitton, Y. ORCID: https://orcid.org/0000-0002-4479-0636, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Kirwan, J. ORCID: https://orcid.org/0000-0002-5423-1651
Metabolites 9
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21 August 2019
Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.
Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K.T., Fragoulis, At., Kühl, A.A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Apostolova, I., Gerling, M., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Hughes, R., Lewis, C.E., Brenner, W., Malinowski, M.B., Stockmann, M., Schomburg, L. ORCID: https://orcid.org/0000-0001-9445-1555, Faller, W. ORCID: https://orcid.org/0000-0002-0738-2254, Sansom, O.J. ORCID: https://orcid.org/0000-0001-9540-3010, Tacke, F., Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999 and Cramer, T. ORCID: https://orcid.org/0000-0002-6462-239X
Oncogene 38
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11 July 2019
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.
Ackermann, T. ORCID: https://orcid.org/0000-0002-9982-8697, Hartleben, G., Müller, C. ORCID: https://orcid.org/0000-0003-1974-4053, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Groth, M. ORCID: https://orcid.org/0000-0002-9199-8990, Sterken, B.A. ORCID: https://orcid.org/0000-0003-1327-1734, Zaini, M.A., Youssef, S.A. ORCID: https://orcid.org/0000-0002-6402-9975, Zuidhof, H.R. ORCID: https://orcid.org/0000-0002-4893-633X, Krauss, S.R., Kortman, G., de Haan, G. ORCID: https://orcid.org/0000-0001-9706-0138, de Bruin, A. ORCID: https://orcid.org/0000-0001-8579-2649, Wang, Z.Q., Platzer, M. ORCID: https://orcid.org/0000-0003-0596-8582, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Calkhoven, C.F. ORCID: https://orcid.org/0000-0001-6318-7210
Communications Biology 2
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14 June 2019
Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Balogh, A. ORCID: https://orcid.org/0000-0001-8756-747X, Yakoub, M., Homann, S., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, Höges, S., Tsvetkov, D. ORCID: https://orcid.org/0000-0002-6472-971X, Krannich, A. ORCID: https://orcid.org/0000-0002-4025-6495, Wundersitz, S., Avery, E.G. ORCID: https://orcid.org/0000-0002-9094-1423, Haase, N. ORCID: https://orcid.org/0000-0003-0727-1738, Kräker, K. ORCID: https://orcid.org/0000-0002-4032-5382, Hering, L., Maase, M., Kusche-Vihrog, K., Grandoch, M., Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934, Zhumadilov, Z., Kozhakhmetov, S., Kushugulova, A., Eckardt, K.U., Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Rump, L.C., Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Stegbauer, J. and Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364
Circulation 139
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12 March 2019
Stage-specific metabolic features of differentiating neurons: implications for toxicant sensitivity.
Delp, J., Gutbier, S., Cerff, M., Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Niedenführ, S., Zhao, L., Smirnova, L., Hartung, T., Borlinghaus, H., Schreiber, F., Bergemann, J., Gätgens, J., Beyss, M., Azzouzi, S., Waldmann, T., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Nöh, K. and Leist, M.
Toxicology and Applied Pharmacology 354
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1 September 2018
Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates.
Langer, H.T. ORCID: https://orcid.org/0000-0003-1838-4279, Senden, J.M.G., Gijsen, A.P., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, van Loon, Luc J. C. and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
Frontiers in Physiology 9
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31 August 2018
Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Fritsche-Guenther, R. ORCID: https://orcid.org/0000-0002-6965-0226, Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Royla, N., Rainer, R., Roßner, F., Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Klipp, E. ORCID: https://orcid.org/0000-0002-0567-7075, Sers, C. and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Scientific Reports 8
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15 June 2018
Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: a comprehensive examination of the potential carriers for semiochemicals.
Iovinella, I., McAfee, A., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Foster, L.J., Pelosi, P. and Dani, F.R.
Journal of Proteomics 181
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15 June 2018
Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M. ORCID: https://orcid.org/0000-0002-6863-841X, Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Walcher, J., Kühnemund, J., Cheret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 32
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10 May 2018
Combined human genome-wide RNAi and metabolite analyses identify IMPDH as a host-directed target against Chlamydia infection.
Rother, M., Gonzalez, E., Teixeira da Costa, A.R., Wask, L., Gravenstein, I., Pardo, M., Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Gurumurthy, R.K., Angermann, J., Laudeley, R., Glage, S., Meyer, M., Chumduri, C., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Dinkel, K., Unger, A., Klebl, B., Klos, A. and Meyer, T.F.
Cell Host & Microbe 23
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(7): 1193-1200.
July 2011
Odorant-binding proteins and chemosensory proteins in pheromone detection and release in the silkmoth Bombyx mori.
Dani, F.R., Michelucci, E., Francese, S., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Cappellozza, S., La Marca, G., Niccolini, A., Felicioli, A., Moneti, G. and Pelosi, P.
Chemical Senses 36
(4): 335-344.
May 2011
Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(III) compounds studied with combined mass spectrometry and biochemical assays.
Gabbiani, C., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Sorrentino, F., Dani, B., Rigobello, M.P., Bindoli, A., Cinellu, M.A., Pieraccini, G., Messori, L. and Casini, A.
MedChemComm 2
(1): 50-54.
January 2011
Targeted proteomics for Chlamydomonas reinhardtii combined with rapid subcellular protein fractionation, metabolomics and metabolic flux analyses.
Wienkoop, S., Weiss, J., May, P., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Irgang, S., Recuenco-Munoz, L., Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Schwemmer, T., Rupprecht, J., Egelhofer, V. and Weckwerth, W.
Molecular BioSystems 6
(6): 1018-1031.
18 June 2010
An integrative approach towards completing genome-scale metabolic networks.
Christian, N., May, P., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Handorf, T. and Ebenhoeh, O.
Molecular BioSystems 5
(12): 1889-1903.
December 2009
Carbon metabolism and bacteroid functioning are involved in the regulation of nitrogen fixation in Medicago truncatula under drought and recovery.
Larrainzar, E., Wienkoop, S., Scherling, C., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Ladrera, R., Arrese-Igor, C., Weckwerth, W. and Gonzalez, E.M.
Molecular Plant-Microbe Interactions 22
(12): 1565-1576.
December 2009
ChlamyCyc: an integrative systems biology database and web-portal for Chlamydomonas reinhardtii.
May, P., Christian, J.O., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Walther, D.
BMC Genomics 10
: 209.
4 May 2009
An automated GCxGC-TOF-MS protocol for batch-wise extraction and alignment of mass isotopomer matrixes from differential 13C-labelling experiments: a case study for photoautotrophic-mixotrophic grown Chlamydomonas reinhardtii cells.
Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Hummel, J., Schwemmer, T., Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Strehmel, N., Wienkoop, S., Kopka, J. and Weckwerth, W.
Journal of Basic Microbiology 49
(1): 82-91.
February 2009
A central role of abscisic acid in stress-regulated carbohydrate metabolism.
Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Krasensky, J., Dal Santo, S., Kopka, J. and Jonak, C.
PLoS ONE 3
(12): e3935.
12 December 2008
Metabolomics- and proteomics-assisted genome annotation and analysis of the draft metabolic network of Chlamydomonas reinhardtii.
May, P., Wienkoop, S., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Usadel, B., Christian, N., Rupprecht, J., Weiss, J., Recuenco-Munoz, L., Ebenhoeh, O., Weckwerth, W. and Walther, D.J.
Genetics 179
(1): 157-166.
1 May 2008
A plastid-localized glycogen synthase kinase 3 modulates stress tolerance and carbohydrate metabolism.
Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Rozhon, W., Samaj, J., Erban, A., Baluska, F., Becker, T., Haselmayer, J., Schleiff, E., Kopka, J., Hirt, H. and Jonak, C.
Plant Journal 49
(6): 1076-1090.
March 2007
Towards dissecting nutrient metabolism in plants: a systems biology case study on sulphur metabolism.
Nikiforova, V.J., Gakiere, B., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Adamik, M., Willmitzer, L., Hesse, H. and Hoefgen, R.
Journal of Experimental Botany 55
(404): 1861-1870.
August 2004
Muscle-type creatine kinase interacts with central domains of the M-band proteins myomesin and M-protein.
Hornemann, T., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Himmel, M., Hayess, K., Fuerst, D.O. and Wallimann, T.
Journal of Molecular Biology 332
(4): 877-887.
26 September 2003
Transcriptome analysis of sulfur depletion in Arabidopsis thaliana: interlacing of biosynthetic pathways provides response specificity.
Nikiforova, V., Freitag, J., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Adamik, M., Hesse, H. and Hoefgen, R.
Plant Journal 33
(4): 633-650.
February 2003
Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.
van der Ven, P.F., Wiesner, S., Salmikangas, P., Auerbach, D., Himmel, M., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Hayess, K., Pacholsky, D., Taivainen, A., Schroeder, R., Carpen, O. and Fuerst, D.O.
Journal of Cell Biology 151
(2): 235-248.
16 October 2000
Book Section
Systems biology approach to study cancer metabolism.
Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Royla, N.
In:
Encyclopedia of Cancer.
Elsevier / Academic Press, 426-428.
ISBN 978-0-12-812485-7
2019
Genome-Scale Metabolic Network Inference.
Ebenhöh, O. and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
In:
Encyclopedia of Systems Biology.
Springer New York, New York, NY, 832-833.
ISBN 978-1-4419-9862-0
8 July 2014
Metabolic and signaling networks.
Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
In:
Encyclopedia of Systems Biology.
Springer, New York, NY, 1228-1229.
ISBN 978-1-4419-9862-0
5 June 2013
Review
Sodium as an important regulator of immunometabolism.
Miyauchi, H. ORCID: https://orcid.org/0000-0003-0961-7130, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199, Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364, Stegbauer, J. ORCID: https://orcid.org/0000-0001-8994-8102, Wiig, H. ORCID: https://orcid.org/0000-0002-7740-8210, Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Jantsch, J., Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Mueller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644
Hypertension 81
(3): 426-435.
March 2024
Wie Kochsalz Mitochondrien beeinflusst.
Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312
BIOspektrum 28
(4): 387-389.
June 2022
Analysing central metabolism in ultra-high resolution: at the crossroads of carbon and nitrogen.
Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Fürst, S., Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Molecular Metabolism 33
: 38-47.
19 March 2020
Pulsed stable isotope-resolved metabolomic studies of cancer cells.
Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Methods in Enzymology 543
: 179-198.
9 June 2014
The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.
Rohwer, N., Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Cramer, T.
Oncogene 32
(31): 3569-3576.
1 August 2013
Effect of sulfur availability on the integrity of amino acid biosynthesis in plants.
Nikiforova, V.J., Bielecka, M., Gakiere, B., Krueger, S., Rinder, J., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Morcuende, R., Scheible, W.R., Hesse, H. and Hoefgen, R.
Amino Acids 30
(2): 173-183.
March 2006
Engineering of cysteine and methionine biosynthesis in potato.
Nikiforova, V., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Zeh, M., Maimann, S., Kreft, O., Casazza, A.P., Riedel, K., Tauberger, E., Hoefgen, R. and Hesse, H.
Amino Acids 22
(3): 259-278.
April 2002
Editorial
Targeting HFpEF: unlocking the potential of glucagon receptor blockade.
Santiago Padilla, L. ORCID: https://orcid.org/0000-0002-0873-7205 and Schiattarella, G.G. ORCID: https://orcid.org/0000-0002-7582-7171
Circulation Research 135
(5): 629-631.
16 August 2024
Salt sensitivity includes effects on immune cell signalling and metabolism.
Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149 and Jantsch, J.
Nature Reviews Immunology 23
(6): 341-342.
June 2023
Preprint
Integrating UHPLC-MS and MALDI-MSI for spatial nucleoside profiling in FFPE breast cancer: a multimodal molecular pathology framework.
Wu, Jierong ORCID: https://orcid.org/0000-0002-2413-0411, Geisberger, Sabrina Y. ORCID: https://orcid.org/0000-0001-6477-1312, Mastrobuoni, Guido ORCID: https://orcid.org/0000-0003-4509-1295, Lisek, Kamil ORCID: https://orcid.org/0000-0002-2406-8830, Raimundo, Sandra ORCID: https://orcid.org/0009-0000-3353-5456, Nebrich, Grit, Grzeski, Marta, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Klauschen, Frederick ORCID: https://orcid.org/0000-0002-9131-2389, Klein, Oliver ORCID: https://orcid.org/0000-0001-7984-7607 and Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299
bioRxiv
: 2026.01.28.701949.
30 January 2026
Butyrate rescues cardiac metabolic dysfunction in hypertensive heart failure with preserved ejection fraction.
Kedziora, Sarah M. ORCID: https://orcid.org/0000-0003-0124-2557, Geisberger, Sabrina Y. ORCID: https://orcid.org/0000-0001-6477-1312, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Frolova, Alina ORCID: https://orcid.org/0000-0001-5469-7366, Uhrbach, Alisa, Kräker, Kristin ORCID: https://orcid.org/0000-0002-4032-5382, Tagiyeva, Nurana ORCID: https://orcid.org/0009-0006-7918-1220, Kelm, Marcus, Berndt, Nikolaus, Zhang, Yiming D. ORCID: https://orcid.org/0009-0003-9465-2033, Mastrobuoni, Guido ORCID: https://orcid.org/0000-0003-4509-1295, Escrihuela-Branz, Raquel, Bartolomaeus, Theda U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Pixner, Lorenz, Fahjen, Pauline ORCID: https://orcid.org/0000-0002-5015-0643, Kaufhold, Gelsomina N. ORCID: https://orcid.org/0009-0009-0868-3284, Parakkat, Pragati ORCID: https://orcid.org/0000-0003-2691-791X, Chitroceanu, Alexandra Maria, Tschöpe, Carsten, Edelmann, Frank, Schiattarella, Gabriele G. ORCID: https://orcid.org/0000-0002-7582-7171, Forslund, Sofia K. ORCID: https://orcid.org/0000-0003-4285-6993, Wilck, Nicola ORCID: https://orcid.org/0000-0003-3189-5364, Gotthardt, Michael ORCID: https://orcid.org/0000-0003-1788-3172, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Sawamiphak, Suphansa ORCID: https://orcid.org/0000-0003-2298-3565, Müller, Dominik N. ORCID: https://orcid.org/0000-0003-3650-5644, Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299 and Haase, Nadine ORCID: https://orcid.org/0000-0003-0727-1738
bioRxiv
: 2025.11.28.690152.
30 November 2025
Sociality shapes mitochondrial adaptations supporting hypoxia tolerance.
Rossi, A. ORCID: https://orcid.org/0000-0002-8819-9813, Ruwolt, M. ORCID: https://orcid.org/0009-0000-7220-406X, Kakouri, P., Kosten, T., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Puchkov, D. ORCID: https://orcid.org/0000-0001-8341-4847, Reznick, J. ORCID: https://orcid.org/0000-0001-7921-5466, Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Omerbašić, D. ORCID: https://orcid.org/0000-0003-1839-4856, Méndez Aranda, D. ORCID: https://orcid.org/0000-0001-9668-941X, Carai, G., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Hart, D.W. ORCID: https://orcid.org/0000-0002-4592-558X, Carraro, M. ORCID: https://orcid.org/0000-0002-4573-9306, Tommasin, L. ORCID: https://orcid.org/0000-0002-6029-0375, Bennett, N.C. ORCID: https://orcid.org/0000-0001-9748-2947, Bégay, V. ORCID: https://orcid.org/0000-0002-9002-4211, Faelber, K., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Bernardi, P. ORCID: https://orcid.org/0000-0001-9187-3736, Park, T.J. ORCID: https://orcid.org/0000-0002-2447-2948, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Liu, F. and Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352
bioRxiv
: 2024.09.30.615914.
2 October 2024
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