Browse by Research Team

American Journal of Human Genetics

Mutations in TBX18 cause dominant urinary tract malformations via transcriptional dysregulation of ureter development.
Vivante, Asaf, Kleppa, M.J., Schulz, J., Kohl, S., Sharma, A., Chen, J., Shril, S., Hwang, D.Y., Weiss, A.C., Kaminski, M.M., Shukrun, R., Kemper, M.J., Lehnhardt, A., Beetz, R., Sanna-Cherchi, S., Verbitsky, M., Gharavi, A.G., Stuart, H.M., Feather, S.A., Goodship, J.A., Goodship, T.H.J., Woolf, A.S., Westra, S.J., Doody, D.P., Bauer, S.B., Lee, R.S., Adam, R.M., Lu, W., Reutter, H.M., Kehinde, E.O., Mancini, E.J., Lifton, R.P., Tasic, V., Lienkamp, S.S., Jüppner, H., Kispert, A. and Hildebrandt, F.
American Journal of Human Genetics 97 (2): 291-301. 6 August 2015

Biomaterials

Tuning the 3D microenvironment of reprogrammed tubule cells enhances biomimetic modeling of polycystic kidney disease.
Pichler, R., Rizzo, L., Tröndle, K., Bühler, M., Brucker, H., Müller, A.L., Grand, K., Farè, S., Viau, A., Kaminski, M.M., Kuehn, E.W., Koch, F., Zimmermann, S., Koltay, P. and Lienkamp, S.S.
Biomaterials 291 : 121910. December 2022

Cell and Tissue Research

Engineering kidney cells: reprogramming and directed differentiation to renal tissues.
Kaminski, M.M., Tosic, J., Pichler, R., Arnold, S.J. and Lienkamp, S.S.
Cell and Tissue Research 369 (1): 185-197. July 2017

Cells

Impact of diabetic stress conditions on renal cell metabolome.
Lagies, S., Pichler, R., Bork, T., Kaminski, M.M., Troendle, K., Zimmermann, S., Huber, T.B., Walz, G., Lienkamp, S.S. and Kammerer, B.
Cells 8 (10): 1141. 24 September 2019

Development

Deep learning is widely applicable to phenotyping embryonic development and disease.
Naert, T., Çiçek, Ö., Ogar, P., Bürgi, M., Shaidani, N.I., Kaminski, M.M., Xu, Y., Grand, K., Vujanovic, M., Prata, D., Hildebrandt, F., Brox, T., Ronneberger, O., Voigt, F.F., Helmchen, F., Loffing, J., Horb, M.E., Willsey, H.R. and Lienkamp, S.S.
Development 148 (21): dev199664. 1 November 2021

EMBO Molecular Medicine

CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.
Greensmith, R., Lape, I.T., Riella, C.V., Schubert, A.J., Metzger, J.J., Dighe, A.S., Tan, X., Hemmer, B., Rau, J., Wendlinger, S., Diederich, N., Schütz, A., Riella, L.V. and Kaminski, M.M.
EMBO Molecular Medicine 16 (10): 2619-2637. 14 October 2024

Journal of General Virology

Plasmacytoid dendritic cells and Toll-like receptor 7-dependent signalling promote efficient protection of mice against highly virulent influenza A virus.
Kaminski, M.M., Ohnemus, A., Cornitescu, M. and Staeheli, P.
Journal of General Virology 93 (Pt 3): 555-559. March 2012

Journal of Virology

Pandemic 2009 H1N1 influenza A virus carrying a Q136K mutation in the neuraminidase gene is resistant to zanamivir but exhibits reduced fitness in the guinea pig transmission model.
Kaminski, M.M., Ohnemus, A., Staeheli, P. and Rubbenstroth, D.
Journal of Virology 87 (3): 1912-1915. February 2013

Journal of the American Society of Nephrology

HNF1B alters an evolutionarily conserved nephrogenic program of target genes.
Grand, K., Stoltz, M., Rizzo, L., Röck, R., Kaminski, M.M., Salinas, G., Getwan, M., Naert, T., Pichler, R. and Lienkamp, S.S.
Journal of the American Society of Nephrology 34 (3): 412-432. March 2023

A dominant mutation in nuclear receptor interacting protein 1 causes urinary tract malformations via dysregulation of retinoic acid signaling.
Vivante, A., Mann, N., Yonath, H., Weiss, A.C., Getwan, M., Kaminski, M.M., Bohnenpoll, T., Teyssier, C., Chen, J., Shril, S., van der Ven, A.T., Ityel, H., Schmidt, J.M., Widmeier, E., Bauer, S.B., Sanna-Cherchi, S., Gharavi, A.G., Lu, W., Magen, D., Shukrun, R., Lifton, R.P., Tasic, V., Stanescu, H.C., Cavaillès, V., Kleta, R., Anikster, Y., Dekel, B., Kispert, A., Lienkamp, S.S. and Hildebrandt, F.
Journal of the American Society of Nephrology 28 (8): 2364-2376. August 2017

Macromolecular Bioscience

Fabrication of kidney proximal tubule grafts using biofunctionalized electrospun polymer scaffolds.
Jansen, K., Castilho, M., Aarts, S., Kaminski, M.M., Lienkamp, S.S., Pichler, R., Malda, J., Vermonden, T., Jansen, J. and Masereeuw, R.
Macromolecular Bioscience 19 (2): e1800412. February 2019

Nature Biomedical Engineering

CRISPR-based diagnostics.
Kaminski, M.M., Abudayyeh, O.O., Gootenberg, J.S., Zhang, F. and Collins, J.J.
Nature Biomedical Engineering 5 (7): 643-656. July 2021

A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection.
Kaminski, M.M., Alcantar, M.A., Lape, I.T., Greensmith, R., Huske, A.C., Valeri, J.A., Marty, F.M., Klämbt, V., Azzi, J., Akalin, E., Riella, L.V. and Collins, J.J.
Nature Biomedical Engineering 4 (6): 601-609. June 2020

Nature Cell Biology

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Kaminski, M.M., Tosic, J., Kresbach, C., Engel, H., Klockenbusch, J., Müller, A.L., Pichler, R., Grahammer, F., Kretz, O., Huber, T.B., Walz, G., Arnold, S.J. and Lienkamp, S.S.
Nature Cell Biology 18 (12): 1269-1280. December 2016

Nature Nanotechnology

Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs.
Broto, M., Kaminski, M.M., Adrianus, C., Kim, N., Greensmith, R., Dissanayake-Perera, S., Schubert, A.J., Tan, X., Kim, H., Dighe, A.S., Collins, J.J. and Stevens, M.M.
Nature Nanotechnology 17 (10): 1120-1126. October 2022

Nephrology Dialysis Transplantation

Mutations in transcription factor CP2-like 1 may cause a novel syndrome with distal renal tubulopathy in humans.
Klämbt, V., Werth, M., Onuchic-Whitford, A.C., Getwan, M., Kitzler, T.M., Buerger, F., Mao, Y., Deutsch, K., Mann, N., Majmundar, A.J., Kaminski, M.M., Shen, Tian, Schmidt-Ott, K.M., Shalaby, M., El Desoky, S., Kari, J.A., Shril, S., Lienkamp, S.S., Barasch, J. and Hildebrandt, F.
Nephrology Dialysis Transplantation 36 (2): 237-246. February 2021

Science Advances

Synthetic genetic circuits to uncover the OCT4 trajectories of successful reprogramming of human fibroblasts.
Ilia, K., Shakiba, N., Bingham, T., Jones, R.D., Kaminski, M.M., Aravera, E., Bruno, S., Palacios, S., Weiss, R., Collins, J.J., Del Vecchio, D. and Schlaeger, T.M.
Science Advances 9 (48): eadg8495. December 2023

Scientific Reports

Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs).
Lagies, S., Pichler, R., Kaminski, M.M., Schlimpert, M., Walz, G., Lienkamp, S.S. and Kammerer, B.
Scientific Reports 8 (1): 3878. 1 March 2018

bioRxiv

Single-stranded HDR templates with truncated Cas12a binding sequences improve knock-in efficiencies in primary human T cells.
Nitulescu, A.M., Du, W., Glaser, V., Kath, J., Greensmith, R., Mikkelsen, N.S., Stein, M., Bak, R., Kaminski, M.M. and Wagner, D.L.
bioRxiv : 2024.09.11.608426. 11 September 2024