Browse by Research Team

2009

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H., Paul, F.E., Cheret, C., Garratt, A.N., Zurborg, S., Feinberg, K., Besser, D., Schulz, H., Peles, E., Selbach, M., Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

2008

Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4.
Caubit, X., Lye, C.M., Martin, E., Core, N., Long, D.A., Vola, C., Jenkins, D., Garratt, A.N., Skaer, H., Woolf, A.S. and Fasano, L.
Development 135 (19): 3301-3310. October 2008

2007

Notch signaling is essential for ventricular chamber development.
Grego-Bessa, J., Luna-Zurita, L., del Monte, G., Bolos, V., Melgar, P., Arandilla, A., Garratt, A.N., Zang, H., Mukouyama, Y.S., Chen, H., Shou, W., Ballestar, E., Esteller, M., Rojas, A., Perez-Pomares, J.M. and de la Pompa, J.L.
Developmental Cell 12 (3): 415-429. March 2007

2006

Control of peripheral nerve myelination by the β-secretase BACE1.
Willem, M., Garratt, A.N., Novak, B., Citron, M., Kaufmann, S., Rittger, A., Destrooper, B., Saftig, P., Birchmeier, C. and Haass, C.
Science 314 (5799): 664-666. 27 October 2006

"To erb-B or not to erb-B..." Neuregulin-1/ErbB signaling in heart development and function.
Garratt, A.N.
Journal of Molecular and Cellular Cardiology 41 (2): 215-218. August 2006

Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation.
Lopez-Bendito, G., Cautinat, A., Sanchez, J.A., Bielle, F., Flames, N., Garratt, A.N., Talmage, D.A., Role, L.W., Charnay, P., Marin, O. and Garel, S.
Cell 125 (1): 127-142. 7 April 2006

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.
Atanasoski, S., Scherer, S.S., Sirkowski, E., Leone, D., Garratt, A.N., Birchmeier, C. and Suter, U.
Journal of Neuroscience 26 (7): 2124-2131. 15 February 2006

2005

Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors.
Humphries, J.D., Schofield, N.R., Mostafavi-Pour, Z., Green, L.J., Garratt, A.N., Mould, A.P. and Humphries, M.J.
Journal of Biological Chemistry 280 (11): 10234-10243. 18 March 2005

2004

Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1.
Flames, N., Long, J.E., Garratt, A.N., Fischer, T.M., Gassmann, M., Birchmeier, C., Lai, C., Rubenstein, J.L. and Marin, O.
Neuron 44 (2): 251-261. 14 October 2004

Met provides essential signals for liver regeneration.
Borowiak, M., Garratt, A.N., Wuestefeld, T., Strehle, M., Trautwein, C. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 101 (29): 10608-10613. 1 January 2004

2003

ErbB2 pathways in heart and neural diseases.
Garratt, A.N., Ozcelik, C. and Birchmeier, C.
Trends in Cardiovascular Medicine 13 (2): 80-86. February 2003

2002

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S., Hübner, N., Chien, K.R., Birchmeier, C. and Garratt, A.N.
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Trastuzumab cardiotoxicity: Speculations regarding pathophysiology and targets for further study.
Schneider, J.W., Chang, A.Y. and Garratt, A.
Seminars in Oncology 29 (3): 22-28. June 2002

2000

A dual role of erbB2 in myelination and in expansion of the Schwann cell precursor pool.
Garratt, A.N., Voiculescu, O., Topilko, P., Charnay, P. and Birchmeier, C.
Journal of Cell Biology 148 (5): 1035-1046. 6 March 2000