2026
Unpaired data as a first-order challenge in single-cell and spatial proteomics.
Koutrouli, Mikaela, Finotello, Francesca, Schoof, Erwin M. 
ORCID: https://orcid.org/0000-0002-3117-7832 and Roussos, Panos ORCID: https://orcid.org/0000-0002-4640-6239
Nature Biotechnology 44
(6): 891-892.
June 2026
Spatial single-cell proteomics reveals molecular trajectories of tangle-bearing neurons in Alzheimer’s disease.
Foiani, M.S. ORCID: https://orcid.org/0000-0003-4157-2606, Bourdenx, M. ORCID: https://orcid.org/0000-0002-9799-9222, Kraller, L. ORCID: https://orcid.org/0009-0006-9785-3596, Nirujogi, R.S. ORCID: https://orcid.org/0000-0002-3177-8566, Yiu, A., Davies, H., Patel, S., Damoc, L.S., Mitchener, L., Jaunmuktane, Z. ORCID: https://orcid.org/0000-0001-7738-8881, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081 and Duff, K.E. ORCID: https://orcid.org/0000-0002-6177-868X
bioRxiv
: 2026.04.26.720932.
29 April 2026
Deep visual proteomics uncovers nociceptor diversity and pain targets.
Chakrabarti, Sampurna ORCID: https://orcid.org/0000-0002-2750-3877, Makhmut, Anuar ORCID: https://orcid.org/0009-0009-6913-4289, Mohammadi, Atena, Luo, Wenhan ORCID: https://orcid.org/0000-0001-5202-8855, Wang, Lin ORCID: https://orcid.org/0000-0002-8395-6184, Lewin, Gary R. ORCID: https://orcid.org/0000-0002-2890-6352 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
Nature Communications 17
(1): 3437.
13 April 2026
Deep visual proteomics uncovers nociceptor diversity and pain targets.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
10 April 2026
Lipid nanoparticle-based non-viral in situ gene editing of congenital ichthyosis-causing mutations in human skin models.
Apaydin, Dilem Ceren, Sadhnani, Gaurav ORCID: https://orcid.org/0009-0000-9803-410X, Carlaw, Tiffany, Renziehausen, Jan, Lizunova, Elena, Filor, Viviane, Hiller, Anna, Brumhard, Sophia, Halim, Vincent, Brüning, Ulrike ORCID: https://orcid.org/0000-0003-0112-4032, Bischof, Johannes, Marodin, Rafaela Horbach, Kurek, Daniel Z., Rhiel, Manuel, Ammann, Sandra, Cornu, Tatjana I., Cathomen, Toni, Sander, Leif Erik, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Kirwan, Jennifer ORCID: https://orcid.org/0000-0002-5423-1651, Koller, Ulrich, Gruber, Achim D., Bäumer, Wolfgang and Hedtrich, Sarah ORCID: https://orcid.org/0000-0001-6770-3657
Cell Stem Cell 33
(2): 233-252.e12.
5 February 2026
Non-viral in situ gene editing effectively and safely rescues congenital ichthyosis-causing mutations in human skin.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
23 January 2026
The IBEX knowledge-base a community resource enabling adoption and development of immunofluorescence imaging methods.
Yaniv, Ziv, Anidi, Ifeanyichukwu U., Arakkal, Leanne, Arroyo-Mejías, Armando J., Beuschel, Rebecca T., Börner, Katy, Chu, Colin J., Clark, Beatrice, Clatworthy, Menna R., Colautti, Jake, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Croteau, Joshua, Denha, Saven, Dever, Rose, Dutra, Walderez O., Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Fullam, Spencer, Gerner, Michael Y., Gola, Anita, Gollob, Kenneth J., Hernandez, Jonathan M., Hor, Jyh Liang, Ichise, Hiroshi, Jing, Zhixin, Jonigk, Danny, Kandov, Evelyn, Kastenmüller, Wolfgang, Koenig, Joshua F.E., Kothurkar, Aanandita, Kortekaas, Rosa K., Kreins, Alexandra Y., Lamborn, Ian T., Lin, Yuri, Morais, Katia Luciano Pereira, Lunich, Aleksandra, Luz, Jean C.S., MacDonald, Ryan B., Makranz, Chen, Maltez, Vivien I., McDonough, John E., Moriarty, Ryan V., Ocampo-Godinez, Juan M., Olyntho, Vitoria M., Oxenius, Annette, Padhan, Kartika, Remmert, Kirsten, Richoz, Nathan, Schrom, Edward C., Shang, Wanjing, Shi, Lihong, Shih, Rochelle M., Speranza, Emily, Stierli, Salome, Teichmann, Sarah A., Veres, Tibor Z., Vierhout, Megan, Wachter, Brianna T., Wade-Vallance, Adam K., Williams, Margaret, Zangger, Nathan, Germain, Ronald N. and Radtke, Andrea J.
eLife 14
: RP105737.
23 January 2026
OpenDVP: an experimental and computational framework for community-empowered deep visual proteomics.
Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799, Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Valdes, Daniela S. ORCID: https://orcid.org/0000-0002-1309-5147, Trinh, Minh Tien ORCID: https://orcid.org/0009-0000-2727-8449, Pentimalli, Tancredi ORCID: https://orcid.org/0000-0002-8461-7918, Klingeberg, Melissa ORCID: https://orcid.org/0009-0002-4778-2874, Schallenberg, Simon ORCID: https://orcid.org/0000-0002-7897-7116, Klauschen, Frederick ORCID: https://orcid.org/0000-0002-9131-2389, Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134, Florian, Stefan ORCID: https://orcid.org/0000-0002-0193-1320, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
bioRxiv
: 2025.07.13.662099v2.
15 January 2026
Design of combination therapeutics from protein response to drugs in ovarian cancer cells.
Franz, A., Shen, C., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Munroe, K., Charaoui, L., Korkut, A. ORCID: https://orcid.org/0000-0001-8072-9026, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799, Luna, A. ORCID: https://orcid.org/0000-0001-5709-371X and Sander, C. ORCID: https://orcid.org/0000-0001-6059-6270
bioRxiv
: 2025.04.28.651139.
8 January 2026
An ultrasensitive spatial tissue proteomics workflow exceeding 100 proteomes per day.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
5 January 2026
Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Makhmut, Anuar ORCID: https://orcid.org/0009-0009-6913-4289, Dragomir, Mihnea P., Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Moebs, Markus ORCID: https://orcid.org/0000-0002-1502-3032, Schmitt, Wolfgang D. ORCID: https://orcid.org/0000-0002-7870-138X, Taube, Eliane T. ORCID: https://orcid.org/0000-0003-3041-694X and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
Molecular Systems Biology 22
(1): 7-41.
2 January 2026
An ultrasensitive spatial tissue proteomics workflow exceeding 100 proteomes per day.
Klingeberg, Melissa ORCID: https://orcid.org/0009-0002-4778-2874, Krisp, Christoph ORCID: https://orcid.org/0000-0002-4689-1967, Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Schallenberg, Simon, Hornburg, Daniel ORCID: https://orcid.org/0000-0002-6618-7774 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
Molecular & Cellular Proteomics 25
(1): 101489.
January 2026
Immunofluorescence imaging-guided laser microdissection for ultralow input spatial tissue proteomics.
Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
Methods in Molecular Biology 3015
: 83-94.
2026
2025
Functional landscape of ubiquitin linkages couples K29-linked ubiquitylation to epigenome integrity.
Arroyo-Gomez, Javier ORCID: https://orcid.org/0009-0003-7751-1853, Murray, Matthew J. ORCID: https://orcid.org/0000-0002-0379-7161, Guérillon, Claire ORCID: https://orcid.org/0000-0002-1982-6596, Wang, Juanjuan, Isaakova, Ekaterina, Reverón-Gómez, Nazaret ORCID: https://orcid.org/0000-0001-7347-781X, Koutrouli, Mikaela, Suryo Rahmanto, Aldwin, Mitrofanov, Katrine ORCID: https://orcid.org/0009-0009-2181-5552, Ingham, Andreas, Schovsbo, Sofie, Weischenfeldt, Katrine, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Typas, Dimitris, Völker-Albert, Moritz, Solis, Victor, Jensen, Lars Juhl ORCID: https://orcid.org/0000-0001-7885-715X, Groth, Anja, Mund, Andreas ORCID: https://orcid.org/0000-0002-7843-5341, Beli, Petra, Shearer, Robert F. ORCID: https://orcid.org/0000-0003-3012-8788 and Mailand, Niels ORCID: https://orcid.org/0000-0002-6623-709X
EMBO Journal 44
(23): 6944-6978.
December 2025
Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Makhmut, Anuar ORCID: https://orcid.org/0009-0009-6913-4289, Mihnea, Paul Dragomir, Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Möbs, Markus, Schmitt, Wolfgang Daniel, Taube, Eliane Tabea and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
5 November 2025
Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
19 October 2025
Functional landscape of ubiquitin linkages connects K29-linked ubiquitylation to epigenome integrity.
Arroyo-Gomez, J., Murray, M.J., Guérillon, C., Wang, J., Isaakova, E., Reveron-Gome, N., Koutrouli, M., Rahmanto, A.S., Mitrofanov, K., Ingham, A., Schovsbo, S., Weischenfeldt, K., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Typas, D., Völker-Albert, M., Solis, V., Jensen, L.J. ORCID: https://orcid.org/0000-0001-7885-715X, Groth, A., Mund, A., Beli, P., Shearer, R.F. and Mailand, N.
[Dataset]
17 October 2025
Unravelling drug resistant proteotypes through phenotype-resolved proteomics of single-cell derived colonies.
Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Das, Ridhima ORCID: https://orcid.org/0009-0007-0238-5935, Schallenberg, Simon ORCID: https://orcid.org/0000-0002-7897-7116, Riecken, Kristoffer ORCID: https://orcid.org/0000-0001-9050-6766, Tinhofer, Ingeborg ORCID: https://orcid.org/0000-0002-0512-549X and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
bioRxiv
: 2025.10.11.681009v2.
14 October 2025
Extrachromosomal DNA-driven oncogene dosage heterogeneity promotes rapid adaptation to therapy in MYCN-amplified cancers.
Montuori, Giulia, Tu, Fengyu, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Schmargon, Rachel ORCID: https://orcid.org/0009-0009-3535-7185, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Helmsauer, Konstantin ORCID: https://orcid.org/0000-0003-0773-4114, Hui, Hui, Mandal, Susmita, Purshouse, Karin, Fankhänel, Lara, Bosco, Bartolomeo ORCID: https://orcid.org/0000-0002-3069-714X, Spanjaard, Bastiaan ORCID: https://orcid.org/0000-0003-1309-8839, Seyboldt, Hannah, Grunewald, Laura, Schmitt, Matthias Jürgen ORCID: https://orcid.org/0000-0001-8296-5858, Gürgen, Dennis, Buck, Viktoria, Rosenfeldt, Mathias T, Dubois, Frank P.B. ORCID: https://orcid.org/0000-0002-7654-6208, Schallenberg, Simon, Lehmann, Annika, Theißen, Jessica, Taschner-Mandl, Sabine, Koch, Arend, Hundsdoerfer, Patrick, Künkele, Annette, Eggert, Angelika, Fischer, Matthias, Gargiulo, Gaetano ORCID: https://orcid.org/0000-0001-5414-4251, Krieger, Teresa G, Chavez, Lukas, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Werner, Benjamin, Huang, Weini, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Dörr, Jan R. ORCID: https://orcid.org/0000-0002-4927-6548
Cancer Discovery 15
(10): 2054-2077.
6 October 2025
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set.
Distler, Ute ORCID: https://orcid.org/0000-0002-8031-6384, Yoo, Han Byul, Kardell, Oliver, Hein, Dana, Sielaff, Malte, Scherer, Marian, Jozefowicz, Anna M., Leps, Christian, Gomez-Zepeda, David ORCID: https://orcid.org/0000-0002-9467-1213, von Toerne, Christine ORCID: https://orcid.org/0000-0002-4132-4322, Merl-Pham, Juliane ORCID: https://orcid.org/0000-0002-3422-4083, Barth, Teresa K., Tüshaus, Johanna ORCID: https://orcid.org/0000-0001-9206-8093, Giesbertz, Pieter ORCID: https://orcid.org/0000-0001-7461-8602, Müller, Torsten, Kliewer, Georg, Aljakouch, Karim, Helm, Barbara, Unger, Henry ORCID: https://orcid.org/0009-0001-1798-4347, Frey, Dario L. ORCID: https://orcid.org/0000-0001-9572-9686, Helm, Dominic ORCID: https://orcid.org/0000-0001-9321-2069, Schwarzmüller, Luisa ORCID: https://orcid.org/0000-0002-7151-9913, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Wudy, Susanne I. ORCID: https://orcid.org/0009-0001-6333-5233, Sinn, Ludwig Roman ORCID: https://orcid.org/0000-0003-4692-0681, Mergner, Julia ORCID: https://orcid.org/0000-0002-4332-1280, Ludwig, Christina ORCID: https://orcid.org/0000-0002-6131-7322, Imhof, Axel ORCID: https://orcid.org/0000-0003-2993-8249, Kuster, Bernhard ORCID: https://orcid.org/0000-0002-9094-1677, Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575, Krijgsveld, Jeroen, Klingmüller, Ursula, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Ralser, Markus ORCID: https://orcid.org/0000-0001-9535-7413, Mülleder, Michael ORCID: https://orcid.org/0000-0001-9792-3861, Hauck, Stefanie M. ORCID: https://orcid.org/0000-0002-1630-6827 and Tenzer, Stefan ORCID: https://orcid.org/0000-0003-3034-0017
Nature Communications 16
(1): 8774.
2 October 2025
Spatial multiomics of acute myocardial infarction reveals immune cell infiltration through the endocardium.
Wünnemann, Florian, Sicklinger, Florian ORCID: https://orcid.org/0009-0004-6707-1695, Bestak, Kresimir ORCID: https://orcid.org/0009-0009-8245-9846, Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799, Thiemann, Tobias ORCID: https://orcid.org/0009-0003-7284-2127, Amrute, Junedh M ORCID: https://orcid.org/0000-0002-6851-0168, Nordbeck, Mathias ORCID: https://orcid.org/0009-0003-0392-6685, Hartmann, Niklas ORCID: https://orcid.org/0009-0009-1799-7162, Ibarra-Arellano, Miguel A ORCID: https://orcid.org/0000-0001-8411-4854, Tanevski, Jovan ORCID: https://orcid.org/0000-0001-7177-1003, Chazotte, Margot ORCID: https://orcid.org/0009-0007-4901-5173, Heine, Clara ORCID: https://orcid.org/0009-0001-3506-2119, Frey, Norbert, Lavine, Kory J ORCID: https://orcid.org/0000-0003-1948-9945, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Saez-Rodriguez, Julio ORCID: https://orcid.org/0000-0002-8552-8976, Leuschner, Florian ORCID: https://orcid.org/0000-0003-1157-474X and Schapiro, Denis ORCID: https://orcid.org/0000-0002-9391-5722
Nature Cardiovascular Research 4
(10): 1345-1362.
October 2025
Iterative Bleaching Extends Multiplexity (IBEX) Knowledge-Base.
Yaniv, Ziv ORCID: https://orcid.org/0000-0003-0315-7727, Anidi, Ifeanyichukwu ORCID: https://orcid.org/0000-0002-2692-1225, Arakkal, Leanne ORCID: https://orcid.org/0000-0001-9189-7172, Arroyo-Mejias, Armando ORCID: https://orcid.org/0000-0002-0835-911X, Beuschel, Rebecca T. ORCID: https://orcid.org/0000-0002-3882-457X, Börner, Katy ORCID: https://orcid.org/0000-0002-3321-6137, Chu, Colin J. ORCID: https://orcid.org/0000-0003-2088-8310, Clark, Beatrice ORCID: https://orcid.org/0009-0003-9817-7874, Clatworthy, Menna ORCID: https://orcid.org/0000-0002-3340-9828, Colautti, Jake ORCID: https://orcid.org/0000-0002-1461-0999, Croteau, Joshua ORCID: https://orcid.org/0000-0002-8142-0482, Denha, Saven ORCID: https://orcid.org/0009-0004-8162-409X, Dever, Rose ORCID: https://orcid.org/0009-0004-2746-8743, Dutra, Walderez ORCID: https://orcid.org/0000-0002-7586-9996, Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Fullam, Spencer ORCID: https://orcid.org/0000-0001-9012-3802, Gerner, Michael ORCID: https://orcid.org/0000-0001-5406-8308, Gola, Anita ORCID: https://orcid.org/0000-0003-1431-1398, Gollob, Kenneth J. ORCID: https://orcid.org/0000-0003-4184-3867, Ichise, Hiroshi ORCID: https://orcid.org/0000-0002-5187-810X, Jing, Zhixin ORCID: https://orcid.org/0000-0003-1118-7432, Jonigk, Danny ORCID: https://orcid.org/0000-0002-5251-2281, Kandov, Evelyn ORCID: https://orcid.org/0000-0001-7071-9916, Kastenmüller, Wolfgang ORCID: https://orcid.org/0000-0002-3835-1485, Koenig, Joshua F.E. ORCID: https://orcid.org/0000-0002-8909-5039, Kortekaas, Rosa K. ORCID: https://orcid.org/0000-0002-8728-1735, Kothurkar, Aanandita ORCID: https://orcid.org/0009-0000-2047-4228, Krzywańska, Aleksandra ORCID: https://orcid.org/0009-0006-4918-5749, Lamborn, Ian ORCID: https://orcid.org/0009-0006-1490-3667, Lin, Yuri ORCID: https://orcid.org/0009-0006-9784-2694, Luz, Jean Carlos Dos Santos ORCID: https://orcid.org/0000-0001-5088-7808, Makranz, Chen ORCID: https://orcid.org/0000-0002-6944-6997, McNamara, George ORCID: https://orcid.org/0000-0003-4155-0976, Moriarty, Ryan V. ORCID: https://orcid.org/0000-0001-7100-1906, Murakami Olyntho, Vitoria ORCID: https://orcid.org/0000-0003-2634-6838, Padhan, Kartika ORCID: https://orcid.org/0000-0001-9561-4256, Richoz, Nathan ORCID: https://orcid.org/0000-0002-7422-3237, Shang, Wanjing ORCID: https://orcid.org/0009-0007-0646-7946, Shi, Lihong ORCID: https://orcid.org/0000-0002-6604-2065, Shih, Rochelle ORCID: https://orcid.org/0000-0002-3218-4479, Speranza, Emily ORCID: https://orcid.org/0000-0003-0666-4804, Teichmann, Sarah ORCID: https://orcid.org/0000-0002-6294-6366, Veres, Tibor Z. ORCID: https://orcid.org/0000-0002-6980-8900, Vierhout, Megan ORCID: https://orcid.org/0000-0001-5813-2581, Wachter, Brianna ORCID: https://orcid.org/0000-0002-2950-2683, Wade-Vallance, Adam K. ORCID: https://orcid.org/0000-0002-6863-1461, Williams, Margaret ORCID: https://orcid.org/0000-0003-3697-5726, Zangger, Nathan ORCID: https://orcid.org/0000-0003-1130-1899, Germain, Ronald N. ORCID: https://orcid.org/0000-0003-1495-9143 and Radtke, Andrea J. ORCID: https://orcid.org/0000-0003-4379-8967
[Dataset]
26 September 2025
Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Makhmut, Anuar ORCID: https://orcid.org/0009-0009-6913-4289 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
26 September 2025
Slice-PASEF: maximising ion utilisation in LC-MS proteomics.
Sinn, Ludwig R. ORCID: https://orcid.org/0000-0003-4692-0681, Szyrwiel, Lukasz ORCID: https://orcid.org/0000-0003-1983-2950, Grossmann, Justus, Lau, Kate, Faisst, Katharina, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Mutschler, Florian ORCID: https://orcid.org/0009-0002-0992-7171, Khoury, Luke ORCID: https://orcid.org/0000-0001-7794-6812, Leduc, Andrew ORCID: https://orcid.org/0000-0001-6234-0623, Ralser, Markus ORCID: https://orcid.org/0000-0001-9535-7413, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Slavov, Nikolai ORCID: https://orcid.org/0000-0003-2035-1820, Nagaraj, Nagarjuna, Steger, Martin ORCID: https://orcid.org/0000-0003-1637-8190 and Demichev, Vadim ORCID: https://orcid.org/0000-0002-2424-9412
bioRxiv
: 2022.10.31.514544v3.
2 September 2025
Spatial omics of acute myocardial infarction reveals a novel mode of immune cell infiltration.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
16 August 2025
Spatial omics of acute myocardial infarction reveals a novel mode of immune cell infiltration.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
16 August 2025
OpenDVP: an experimental and computational framework for community-empowered deep visual proteomics.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081 and Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799
[Dataset]
22 July 2025
(Submitted)
Design of combination therapeutics from protein response to drugs in ovarian cancer cells.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
19 July 2025
Maternal smoking in early pregnancy disrupts placental function through syncytiotrophoblast and macrophage dysregulation.
Valdes, Daniela S. ORCID: https://orcid.org/0000-0002-1309-5147, Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799, Nonn, Olivia ORCID: https://orcid.org/0000-0001-6385-2866, Ulrich, Juliane, Forstner, Désirée ORCID: https://orcid.org/0000-0001-5451-7580, Haider, Sandra ORCID: https://orcid.org/0000-0003-2409-1317, Ressler, Miriam ORCID: https://orcid.org/0000-0002-8669-9451, Pignitter, Marc ORCID: https://orcid.org/0000-0002-5793-8572, Müller, Dominik N. ORCID: https://orcid.org/0000-0003-3650-5644, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Gauster, Martin ORCID: https://orcid.org/0000-0003-0386-6857, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081 and Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134
bioRxiv
: 2025.07.10.664172.
15 July 2025
openDVP tutorial dataset.
Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534 and Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799
[Dataset]
7 July 2025
Extrachromosomal DNA-driven oncogene dosage heterogeneity promotes rapid adaptation to therapy in MYCN-amplified cancers.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
5 July 2025
A proteogenomic view of synchronous endometrioid endometrial and ovarian cancer.
Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Nielsen, A.B. ORCID: https://orcid.org/0009-0005-2855-208X, Weigert, M. ORCID: https://orcid.org/0009-0005-2855-208X, Watters, K. ORCID: https://orcid.org/0000-0002-8260-0098, Javellana, M. ORCID: https://orcid.org/0000-0002-1361-8761, Anglesio, M. ORCID: https://orcid.org/0000-0003-1639-5003, Yamada, S.D. ORCID: https://orcid.org/0000-0001-7922-4784, Lastra, R.R. ORCID: https://orcid.org/0000-0003-0691-5685, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799 and Lengyel, E. ORCID: https://orcid.org/0000-0001-8624-1507
Clinical Cancer Research 31
(11): 2230-2240.
3 June 2025
Spatial proteomics in translational and clinical research.
Horvath, P. ORCID: https://orcid.org/0000-0002-4492-1798 and Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081
Molecular Systems Biology 21
(6): 526-530.
June 2025
Combining spatial transcriptomics and ECM imaging in 3D for mapping cellular interactions in the tumor microenvironment.
Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Schallenberg, S., León-Periñán, D. ORCID: https://orcid.org/0000-0002-7970-0362, Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Theurillat, I. ORCID: https://orcid.org/0000-0002-1125-1951, Thomas, G., Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Ruff, L., Dernbach, G., Jurmeister, P., Murphy, S., Gregory, M.T., Liang, Y., Cordenonsi, M., Piccolo, S., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Klauschen, F. and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Cell Systems 16
(5): 101261.
21 May 2025
openDVP multiplex immunofluorescence demo.
Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799 and Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534
[Dataset]
13 May 2025
Senescent syncytiotrophoblast secretion during early onset preeclampsia.
Nonn, O. ORCID: https://orcid.org/0000-0001-6385-2866, Debnath, O. ORCID: https://orcid.org/0009-0009-2845-055X, Valdes, D.S. ORCID: https://orcid.org/0000-0002-1309-5147, Sallinger, K., Secener, A.K. ORCID: https://orcid.org/0000-0003-4806-2852, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Tiesmeyer, S. ORCID: https://orcid.org/0000-0002-0492-1523, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Kuenzer, T. ORCID: https://orcid.org/0000-0001-6882-1217, Ulrich, J., Maxian, T. ORCID: https://orcid.org/0000-0002-8009-8479, Knöfler, M., Karau, P. ORCID: https://orcid.org/0000-0001-6590-1975, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Kroneis, T. ORCID: https://orcid.org/0000-0002-4761-9340, Frolova, A. ORCID: https://orcid.org/0000-0001-5469-7366, Neuper, L., Haase, N. ORCID: https://orcid.org/0000-0003-0727-1738, Malt, A. ORCID: https://orcid.org/0009-0005-4049-0846, Müller-Bötticher, N. ORCID: https://orcid.org/0000-0001-5103-7282, Kräker, K. ORCID: https://orcid.org/0000-0002-4032-5382, Kedziora, S. ORCID: https://orcid.org/0000-0003-0124-2557, Forstner, D. ORCID: https://orcid.org/0000-0001-5451-7580, Eils, R., Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Haider, S. ORCID: https://orcid.org/0000-0003-2409-1317, Verlohren, S. ORCID: https://orcid.org/0000-0003-3507-8636, Stern, C. ORCID: https://orcid.org/0000-0002-6330-1236, Sugulle, M. ORCID: https://orcid.org/0000-0003-4160-3978, Jones, S. ORCID: https://orcid.org/0000-0002-3106-6155, Thilaganathan, B. ORCID: https://orcid.org/0000-0002-5531-4301, Kaitu'u-Lino, T.J. ORCID: https://orcid.org/0000-0001-6233-9737, Tong, S., Huppertz, B. ORCID: https://orcid.org/0000-0003-4814-2158, El-Heliebi, A. ORCID: https://orcid.org/0000-0002-7679-6856, Staff, A.C. ORCID: https://orcid.org/0000-0001-9247-5721, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Gauster, M. ORCID: https://orcid.org/0000-0003-0386-6857, Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X and Herse, F. ORCID: https://orcid.org/0000-0002-9305-8134
Hypertension 82
(5): 787-799.
May 2025
The IBEX Knowledge-Base: a central resource for multiplexed imaging techniques.
Radtke, A.J. ORCID: https://orcid.org/0000-0003-4379-8967, Anidi, I.U., Arakkal, L., Arroyo-Mejias, A.J., Beuschel, R.T., Börner, K., Chu, C.J., Clark, B., Clatworthy, M.R., Colautti, J., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Croteau, J., Denha, S., Dever, R., Dutra, W.O., Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534, Fullam, S., Gerner, M.Y., Gola, A., Gollob, K.J., Hernandez, J.M., Hor, J.L., Ichise, H., Jing, Z., Jonigk, D., Kandov, E., Kastenmüller, W., Koenig, J.F.E., Kortekaas, R.K., Kothurkar, A., Kreins, A.Y., Lamborn, I.T., Lin, Y., Morais, K.L.P., Lunich, A., Luz, J.C.S., MacDonald, R.B., Makranz, C., Maltez, V.I., McDonough, J.E., Moriarty, R.V., Ocampo-Godinez, J.M., Olyntho, V.M., Oxenius, A., Padhan, K., Remmert, K., Richoz, N., Schrom, E.C., Shang, W., Shi, L., Shih, R.M., Speranza, E., Stierli, S., Teichmann, S.A., Veres, T.Z., Vierhout, M., Wachter, B.T., Wade-Vallance, A.K., Williams, M., Zangger, N., Germain, R.N. and Yaniv, Zi.
PLoS Biology 23
(3): e3003070.
19 March 2025
Multicenter longitudinal quality assessment of MS-based proteomics in plasma and serum.
Kardell, O. ORCID: https://orcid.org/0000-0002-6703-7997, Gronauer, T., von Toerne, C., Merl-Pham, J., König, A.C., Barth, T.K., Mergner, J., Ludwig, C. ORCID: https://orcid.org/0000-0002-6131-7322, Tüshaus, J., Giesbertz, P., Breimann, S. ORCID: https://orcid.org/0000-0002-0305-3373, Schweizer, L., Müller, T., Kliewer, G., Distler, U. ORCID: https://orcid.org/0000-0002-8031-6384, Gomez-Zepeda, D. ORCID: https://orcid.org/0000-0002-9467-1213, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Qin, D. ORCID: https://orcid.org/0000-0002-9730-4072, Teupser, D., Cox, J. ORCID: https://orcid.org/0000-0001-8597-205X, Imhof, A. ORCID: https://orcid.org/0000-0003-2993-8249, Küster, B. ORCID: https://orcid.org/0000-0002-9094-1677, Lichtenthaler, S.F., Krijgsveld, J., Tenzer, S. ORCID: https://orcid.org/0000-0003-3034-0017, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081 and Hauck, S.M. ORCID: https://orcid.org/0000-0002-1630-6827
Journal of Proteome Research 24
(3): 1017-1029.
7 March 2025
Multicenter longitudinal quality assessment of MS-based proteomics in plasma and serum.
Kardell, Oliver, Gronauer, Thomas, von Toerne, Christine, Merl-Pham, Juliane, König, Ann-Christine, Barth, Teresa K., Mergner, Julia, Ludwig, Christina, Tüshaus, Johanna, Giesbertz, Pieter, Breimann, Stephan, Schweizer, Lisa, Müller, Torsten, Kliewer, Georg, Distler, Ute, Gomez-Zepeda, David, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Qin, Di, Teupser, Daniel, Cox, Jürgen, Imhof, Axel, Küster, Bernhard, Lichtenthaler, Stefan F., Krijgsveld, Jeroen, Tenzer, Stefan, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081 and Hauck, Stefanie M.
[Dataset]
7 February 2025
Identification of TTLL8, POTEE, and PKMYT1 as immunogenic cancer-associated antigens and potential immunotherapy targets in ovarian cancer.
Bassoy, E.Y., Raja, R., Rubino, T.E., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Goergen, K., Magtibay, P., Butler, K., Schmitt, A., Oberg, A.L. and Curtis, M. ORCID: https://orcid.org/0000-0002-7152-6929
OncoImmunology 14
(1): 2460276.
31 January 2025
2024
Iterative Bleaching Extends Multiplexity (IBEX) Knowledge-Base.
Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534
[Dataset]
29 July 2024
AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication.
Monjé, N., Dragomir, M.P., Sinn, B.V., Hoffmann, I., Makhmut, A. ORCID: https://orcid.org/0009-0009-6913-4289, Simon, T., Kunze, C.A., Ihlow, J., Schmitt, W.D., Pohl, J., Piwonski, I., Marchenko, S., Keunecke, C., Calina, T.G., Tiso, F., Kulbe, H., Kreuzinger, C., Cacsire Castillo-Tong, D., Sehouli, J., Braicu, E.I. ORCID: https://orcid.org/0000-0001-5357-6001, Denkert, C., Darb-Esfahani, S., Kübler, K., Capper, D. ORCID: https://orcid.org/0000-0003-1945-497X, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Horst, D. ORCID: https://orcid.org/0000-0003-4755-5743, Sers, C. and Taube, E.T. ORCID: https://orcid.org/0000-0003-3041-694X
British Journal of Cancer 13
(8): 1249-1260.
3 May 2024
An automated and fast sample preparation workflow for laser microdissection guided ultrasensitive proteomics.
Makhmut, A. ORCID: https://orcid.org/0009-0009-6913-4289, Qin, D. ORCID: https://orcid.org/0000-0002-9730-4072, Hartlmayr, D., Seth, A. and Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081
Molecular & Cellular Proteomics 23
(5): 100750.
May 2024
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions.
Garvanska, D.H., Alvarado, R.E. ORCID: https://orcid.org/0000-0002-1450-4854, Mundt, F.O., Lindqvist, R., Duel, J.K., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Nilsson, E. ORCID: https://orcid.org/0000-0001-8123-3292, Lokugamage, K., Johnson, B.A., Plante, J.A., Morris, D.R., Vu, M.N., Estes, L.K., McLeland, A.M., Walker, J., Crocquet-Valdes, P.A. ORCID: https://orcid.org/0000-0002-2079-0076, Mendez, B.L. ORCID: https://orcid.org/0000-0001-8541-4904, Plante, K.S., Walker, D.H., Weisser, M.B., Överby, A.K. ORCID: https://orcid.org/0000-0001-6553-0940, Mann, M., Menachery, V.D. and Nilsson, J. ORCID: https://orcid.org/0000-0003-4100-1125
EMBO Reports 25
(2): 902-926.
13 February 2024
2023
A framework for ultra-low-input spatial tissue proteomics.
Makhmut, A. ORCID: https://orcid.org/0009-0009-6913-4289, Qin, D. ORCID: https://orcid.org/0000-0002-9730-4072, Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, König, J. and Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081
Cell Systems 14
(11): 1002-1014.
15 November 2023
What do you most hope spatial molecular profiling will help us understand? Part 2.
Yanai, I., Fertig, E.J., Li, M., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Klughammer, J., Nie, Q., Chen, J. and Coskun, A.F.
Cell Systems 14
(7): 543-546.
19 July 2023
Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M., Terkelsen, T., Bartels, A.S., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G.I., Fang, X., Mann, M. and Moreira, J.M.A.
Gastroenterology 165
(1): 121-132.e5.
July 2023
High-resolution molecular atlas of a lung tumor in 3D.
Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Schallenberg, Simon, León-Periñán, D. ORCID: https://orcid.org/0000-0002-7970-0362, Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Theurillat, I. ORCID: https://orcid.org/0000-0002-1125-1951, Thomas, G., Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Ruff, L., Dernbach, G., Jurmeister, P., Murphy, S., Gregory, M., Liang, Y., Cordenonsi, M., Piccolo, S., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Klauschen, F. and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
bioRxiv
: 2023.05.10.539644.
10 May 2023
Iterative Bleaching Extends Multiplexity (IBEX) Knowledge-Base.
Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534
[Dataset]
3 March 2023
2022
The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G., Vanzo, R., Amitash, S., Martín-Doncel, E., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Mund, A., Lerdrup, M., Benada, J., Boos, D. and Toledo, L.
Molecular Cell 82
(18): 3350-3365.
15 September 2022
Deep Visual Proteomics defines single-cell identity and heterogeneity.
Mund, A. ORCID: https://orcid.org/0000-0002-7843-5341, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Kriston, A., Hollandi, R., Kovács, F., Brunner, A.D., Migh, E., Schweizer, L., Santos, A., Bzorek, M., Naimy, S., Rahbek-Gjerdrum, L.M. ORCID: https://orcid.org/0000-0003-4377-3209, Dyring-Andersen, B., Bulkescher, J., Lukas, C. ORCID: https://orcid.org/0000-0001-7169-6883, Eckert, M.A., Lengyel, E., Gnann, C., Lundberg, E. ORCID: https://orcid.org/0000-0001-7034-0850, Horvath, P. and Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799
Nature Biotechnology 40
(8): 1231-1240.
August 2022
Identification of early neurodegenerative pathways in progressive multiple sclerosis.
Kaufmann, M. ORCID: https://orcid.org/0000-0002-1954-4425, Schaupp, A.L., Sun, R. ORCID: https://orcid.org/0000-0002-4979-1574, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Dendrou, C.A., Cortes, A., Kaur, G. ORCID: https://orcid.org/0000-0001-7722-3956, Evans, H.G., Mollbrink, A., Navarro, J.F. ORCID: https://orcid.org/0000-0002-4035-5258, Sonner, J.K. ORCID: https://orcid.org/0000-0002-4700-272X, Mayer, C., DeLuca, G.C. ORCID: https://orcid.org/0000-0003-0342-5197, Lundeberg, J. ORCID: https://orcid.org/0000-0003-4313-1601, Matthews, P.M. ORCID: https://orcid.org/0000-0002-1619-8328, Attfield, K.E., Friese, M.A. ORCID: https://orcid.org/0000-0001-6380-2420, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799 and Fugger, L. ORCID: https://orcid.org/0000-0003-2883-3226
Nature Neuroscience 25
(7): 944-955.
July 2022
A knowledge graph to interpret clinical proteomics data.
Santos, A. ORCID: https://orcid.org/0000-0002-9163-7730, Colaço, A.R., Nielsen, A.B., Niu, L., Strauss, M., Geyer, P.E., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Albrechtsen, N.J.W. ORCID: https://orcid.org/0000-0003-4230-5753, Mundt, F., Jensen, L.J. ORCID: https://orcid.org/0000-0001-7885-715X and Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799
Nature Biotechnology 40
(5): 692-702.
22 May 2022
K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.
Shearer, R.F. ORCID: https://orcid.org/0000-0003-3012-8788, Typas, D. ORCID: https://orcid.org/0000-0002-8737-1319, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Schovsbo, S. ORCID: https://orcid.org/0000-0002-7173-0911, Kruse, T. ORCID: https://orcid.org/0000-0002-2619-7388, Mund, A. ORCID: https://orcid.org/0000-0002-7843-5341 and Mailand, N. ORCID: https://orcid.org/0000-0002-6623-709X
EMBO Journal 41
(9): e110145.
2 May 2022
Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation.
Brunner, A.D. ORCID: https://orcid.org/0000-0002-2733-7899, Thielert, M., Vasilopoulou, C., Ammar, C. ORCID: https://orcid.org/0000-0003-4310-6908, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Mund, A. ORCID: https://orcid.org/0000-0002-7843-5341, Hoerning, O.B., Bache, N., Apalategui, A., Lubeck, M., Richter, S. ORCID: https://orcid.org/0000-0001-6101-2783, Fischer, D.S. ORCID: https://orcid.org/0000-0002-1293-7656, Raether, O., Park, M.A., Meier, F. ORCID: https://orcid.org/0000-0003-4729-175X, Theis, F.J. ORCID: https://orcid.org/0000-0002-2419-1943 and Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799
Molecular Systems Biology 18
(3): e10798.
1 March 2022
2021
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Kruse, T., Benz, C. ORCID: https://orcid.org/0000-0002-5166-3598, Garvanska, D.H., Lindqvist, R., Mihalic, F., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Inturi, R. ORCID: https://orcid.org/0000-0003-1344-3962, Sayadi, A., Simonetti, L. ORCID: https://orcid.org/0000-0003-1283-9770, Nilsson, E., Ali, M. ORCID: https://orcid.org/0000-0002-8858-6776, Kliche, J., Moliner Morro, A., Mund, A. ORCID: https://orcid.org/0000-0002-7843-5341, Andersson, E., McInerney, G. ORCID: https://orcid.org/0000-0003-2257-7241, Mann, M., Jemth, P. ORCID: https://orcid.org/0000-0003-1516-7228, Davey, N.E., Överby, A.K. ORCID: https://orcid.org/0000-0001-6553-0940, Nilsson, J. ORCID: https://orcid.org/0000-0003-4100-1125 and Ivarsson, Y. ORCID: https://orcid.org/0000-0002-7081-3846
Nature Communications 12
(1): 6761.
19 November 2021
Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics.
Franz, A., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Shen, C., Charaoui, L., Mann, M. and Sander, C. ORCID: https://orcid.org/0000-0001-6059-6270
Journal of Ovarian Research 14
(1): 140.
22 October 2021
Homology-directed repair protects the replicating genome from metabolic assaults.
Somyajit, K., Spies, J., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Kirik, U., Rask, M.B., Lee, J.H., Neelsen, K.J., Mund, A., Jensen, L.J. ORCID: https://orcid.org/0000-0001-7885-715X, Paull, T.T., Mann, M. and Lukas, J.
Developmental Cell 56
(4): 461-477.
22 February 2021
2020
Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin.
Dyring-Andersen, B., Løvendorf, M.B., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Santos, A., Møller, L.B.P., Colaço, A.R., Niu, L., Bzorek, M., Doll, S., Andersen, J.L., Clark, R.A., Skov, L. ORCID: https://orcid.org/0000-0002-4784-9680, Teunissen, M.B.M. ORCID: https://orcid.org/0000-0003-1119-6662 and Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799
Nature Communications 11
(1): 5587.
5 November 2020
FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease.
Hoffmann, S., Pentakota, S., Mund, A., Haahr, P., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Gallo, M., Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799, Taylor, N.M. ORCID: https://orcid.org/0000-0003-0761-4921 and Mailand, N. ORCID: https://orcid.org/0000-0002-6623-709X
EMBO Reports 21
(10): e50662.
5 October 2020
A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis.
Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Doll, S., Bech, J.M., Schweizer, L., Mund, A., Lengyel, E., Lindebjerg, J., Madsen, G.I., Moreira, J.M. and Mann, M.
Journal of Pathology 251
(1): 100-112.
May 2020
2019
Mesothelial cell HIF1α expression is metabolically downregulated by metformin to prevent oncogenic tumor-stromal crosstalk.
Hart, P.C., Kenny, H.A., Grassl, N., Watters, K.M., Litchfield, L.M., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Blaženović, I., Ploetzky, L., Fiehn, O., Mann, M., Lengyel, E. and Romero, I.L.
Cell Reports 29
(12): 4086-4098.
17 December 2019
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts.
Eckert, M.A., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Chryplewicz, A., Chang, J.W., Hernandez, K.M., Pan, S., Tienda, S.M., Nahotko, D.A., Li, G., Blaženović, I., Lastra, R.R., Curtis, M., Yamada, S.D., Perets, R., McGregor, S.M., Andrade, J., Fiehn, O., Moellering, R.E., Mann, M. and Lengyel, E.
Nature 569
(7758): 723-728.
30 May 2019
Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex.
Zhang, G. ORCID: https://orcid.org/0000-0001-7697-7203, Kruse, T., Guasch Boldú, C., Garvanska, D.H., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799, Barisic, M. and Nilsson, J. ORCID: https://orcid.org/0000-0003-4100-1125
EMBO Journal 38
(7): e100977.
1 April 2019
2018
Multi-level proteomics identifies CT45 as a chemosensitivity mediator and immunotherapy target in ovarian cancer.
Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S.D., López-Méndez, B., Nilsson, J., Mund, A., Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799 and Curtis, M.
Cell 175
(1): 159-170.
20 September 2018
Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient.
Doll, S., Kriegmair, M.C., Santos, A., Wierer, M., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Neil, H.M., Porubsky, S., Geyer, P.E., Mund, A., Nuhn, P. and Mann, M.
Molecular Oncology 12
(8): 1296-1307.
August 2018
2016
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Watters, K.M., Curtis, M., Eckert, M.A., Chiang, C.Y., Tyanova, S., Montag, A., Lastra, R.R., Lengyel, E. and Mann, M.
Nature Communications 7
: 12645.
26 August 2016
2013
Regulated intramembrane proteolysis and degradation of murine epithelial cell adhesion molecule mEpCAM.
Hachmeister, M., Bobowski, K.D., Hogl, S., Dislich, B., Fukumori, A., Eggert, C., Mack, B., Kremling, H., Sarrach, S., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Zimmermann, W., Steiner, H., Lichtenthaler, S.F. and Gires, O.
PLoS ONE 8
(8): e71836.
29 August 2013
2011
A novel inhibitory domain of Helicobacter pylori protein CagA reduces CagA effects on host cell biology.
Pelz, C., Steininger, S., Weiss, C., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081 and Vogelmann, R.
Journal of Biological Chemistry 286
(11): 8999-9008.
18 March 2011
This list was generated on Mon Jun 22 23:24:45 2026 UTC.
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