Browse by Research Team

2023

The C-terminus of α-synuclein regulates its dynamic cellular internalization by Neurexin 1β.
Birol, M. and Douzoglou Muñoz, I.I. and Rhoades, E.
Molecular Biology of the Cell 20 September 2023 (In Press)

2022

Enzyme self-label-bound ATTO700 in single-molecule and super-resolution microscopy.
Trumpp, M. and Oliveras, A. and Gonschior, H. and Ast, J. and Hodson, D.J. and Knaus, P. and Lehmann, M. and Birol, M. and Broichhagen, J.
Chemical Communications 58 (99): 13724-13727. 13 December 2022

RS-FISH: precise, interactive, fast, and scalable FISH spot detection.
Bahry, E. and Breimann, L. and Zouinkhi, M. and Epstein, L. and Kolyvanov, K. and Mamrak, N. and King, B. and Long, Xi and Harrington, K.I.S. and Lionnet, T. and Preibisch, S.
Nature Methods 19 (12): 1563-1567. December 2022

2020

Untangling the conformational polymorphism of disordered proteins associated with neurodegeneration at the single-molecule level.
Birol, M. and Melo, A.M.
Frontiers in Molecular Neuroscience 12 : 309. 10 January 2020

2019

Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein.
Birol, M. and Wojcik, S.P. and Miranker, A.D. and Rhoades, E.
PLoS Biology 17 (6): e3000318. 18 June 2019

2018

Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid.
Birol, M. and Kumar, S. and Rhoades, E. and Miranker, A.D.
Nature Communications 9 (1): 1312. 3 April 2018

IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies.
Fung, H.Y.J. and Birol, M. and Rhoades, E.
Current Opinion in Structural Biology 49 : 36-43. April 2018

Targeting the intrinsically disordered proteome using small-molecule ligands.
Wójcik, S. and Birol, M. and Rhoades, E. and Miranker, A.D. and Levine, Z.A.
Methods in Enzymology 611 : 703-734. 2018

2016

Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin.
Kumar, S. and Birol, M. and Miranker, A.D.
Chemical Communications 52 (38): 6391-6394. 11 May 2016

Foldamer-mediated manipulation of a pre-amyloid toxin.
Kumar, S. and Birol, M. and Schlamadinger, D.E. and Wojcik, S.P. and Rhoades, E. and Miranker, A.D.
Nature Communications 7 : 11412. 25 April 2016

2014

Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer.
Birol, M. and Enchev, R.I. and Padilla, A. and Stengel, F. and Aebersold, R. and Betzi, S. and Yang, Y. and Hoh, F. and Peter, M. and Dumas, C. and Echalier, A.
PLoS ONE 9 (8): e105688. 21 August 2014

Structure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins.
Birol, M. and Echalier, A.
Current Protein & Peptide Science 15 (5): 504-517. 2014

2013

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
Echalier, A. and Pan, Y. and Birol, M. and Tavernier, N. and Pintard, L. and Hoh, F. and Ebel, C. and Galophe, N. and Claret, F.X. and Dumas, C.
Proceedings of the National Academy of Sciences of the United States of America 110 (4): 1273-1278. 22 January 2013