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Reproducibility assessment of biventricular strain derived from long-axis feature tracking in travelling volunteers - a study in the Berlin research network for cardiovascular magnetic resonance (BER-CMR)

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Item Type:Article
Title:Reproducibility assessment of biventricular strain derived from long-axis feature tracking in travelling volunteers - a study in the Berlin research network for cardiovascular magnetic resonance (BER-CMR)
Creators Name:Ammann, Clemens, Trauzeddel, Ralf Felix, Müller, Maximilian, Grassow, Leonhard, Hadler, Thomas, Viezzer, Darian, Hickstein, Richard, Zange, Leonora, Blaszczyk, Edyta, Daud, Elias, Schulz-Menger, Jeanette and Gröschel, Jan
Abstract:PURPOSE: To evaluate the reproducibility of biventricular global longitudinal strain (GLS) assessment using cardiovascular magnetic resonance in a multicenter study of travelling volunteers. METHODS: Twenty travelling volunteers were prospectively scanned at four sites with same-vendor scanners at 3.0T (sites I, II, III) and 1.5T (site IV). Cine imaging in three long-axis views was performed using a segmented balanced steady-state free precession sequence with 30 cardiac phases except site II with 25 phases. RESULTS: Imaging and post-processing were carried out successfully for 18 volunteers in a core lab setting. Pairwise comparisons revealed significant differences in left ventricular (LV) GLS between sites I and II (p < 0.001) and sites II and IV (p = 0.013), as well as in right ventricular (RV) GLS between sites I and IV (p = 0.027). RV GLS values were significantly higher at 3.0T (p = 0.024), whereas field strength had no significant impact on LV GLS (p = 0.153). Conversely, the use of 25 cardiac phases at site II was associated with significantly lower LV GLS values (p < 0.001), while RV GLS remained unaffected (p = 0.825). CONCLUSION: When applying feature tracking-based strain in a multicenter study, careful consideration should be given to the temporal resolution for LV longitudinal strain and to magnetic field strength for RV longitudinal strain.
Keywords:Cardiovascular Magnetic Resonance, Strain Imaging, Feature Tracking, Myocardial Function, Travelling Volunteers
Source:International Journal of Cardiovascular Imaging
ISSN:1569-5794
Publisher:Springer
Date:17 October 2025
Official Publication:https://doi.org/10.1007/s10554-025-03540-5
PubMed:View item in PubMed

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