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Bimodal dendritic processing in basket cells drives distinct memory-related oscillations

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Title:Bimodal dendritic processing in basket cells drives distinct memory-related oscillations
Creators Name:Tzilivaki, A., Larkum, M.E. and Schmitz, D.
Abstract:Hippocampal oscillations span from slow to high-frequency bands that are linked to different memory stages and behavioral states. We show that fast spiking basket cells (FSBCs) with bimodal nonlinear dendritic trees modulate these oscillations. Supralinear FSBC dendritic activation enhances high-frequency oscillations, while sublinear activation increases slow oscillatory power, adjusting the Excitation/Inhibition balance in the network. This underscores a new link between FSBCs nonlinear dendritic integration and memory-related oscillations.
Source:bioRxiv
Publisher:Cold Spring Harbor Laboratory Press
Article Number:2024.09.11.612262
Date:14 September 2024
Official Publication:https://doi.org/10.1101/2024.09.11.612262

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