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Generation of two human induced Pluripotent Stem Cell lines derived from myoblasts (MDCi014-A) and from peripheral blood mononuclear cells (MDCi014-B) from the same donor

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Item Type:Article
Title:Generation of two human induced Pluripotent Stem Cell lines derived from myoblasts (MDCi014-A) and from peripheral blood mononuclear cells (MDCi014-B) from the same donor
Creators Name:Metzler, E. and Telugu, N. and Diecke, S. and Spuler, S. and Escobar, H.
Abstract:We describe the generation and characterization of two human induced pluripotent stem cell (hiPSCs) lines reprogrammed from myoblasts and from peripheral blood mononuclear cells (PBMCs) from the same donor. The donor was free of neuromuscular disorders, male and 18 years of age. For reprogramming we used Sendai-virus delivery of the four Yamanaka factors. The pluripotent identity of the hiPSC lines was confirmed by the expression of pluripotency markers and their capacity to differentiate into all three germ layers. These hiPSCs constitute a tool to study tissue of origin specific differences in the identity of hiPSCs.
Keywords:Animals, Mice
Source:Stem Cell Research
ISSN:1873-5061
Publisher:Elsevier
Volume:48
Page Range:101998
Date:October 2020
Official Publication:https://doi.org/10.1016/j.scr.2020.101998
PubMed:View item in PubMed

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