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Erdheim-Chester disease and knee pain in a dialysis patient

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Item Type:Article
Title:Erdheim-Chester disease and knee pain in a dialysis patient
Creators Name:Rademacher, S. and Anagnostopoulos, J. and Luft, F.C. and Kettritz, R.
Abstract:Erdheim–Chester disease is a rare inflammatory condition characterized by a non-Langerhans histiocytic infiltration, involving the skeleton, nervous system, viscera, retroperitoneum and elsewhere. The aetiology is unknown. Positron emission tomography shows areas of involvement. We managed a dialysis patient with knee pain; a bone marrow specimen showed typical CD68 positive, but CD1a negative cells. We initiated interferon-α therapy although other options remain open. In our patient, the simultaneous presence of secondary hyperparathyroidism with tumorous calcifications provided an interesting additional differential diagnostic possibility regarding skeletal pain.
Keywords:Calcification, Dialysis, Erdheim-Chester, Histiocytosis
Source:Clinical Kidney Journal
ISSN:2048-8505
Publisher:Oxford University Press (U.K.)
Volume:7
Number:4
Page Range:402-405
Date:August 2014
Official Publication:https://doi.org/10.1093/ckj/sfu031
PubMed:View item in PubMed

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