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Global, regional and national burden of ischemic heart disease attributable to suboptimal diet, 1990–2023: a Global Burden of Disease study.
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April 2026
2025
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Nature Medicine 31
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December 2025
Helmholtz Health task force to strengthen prevention research and its translation globally.
Nature Medicine 31
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May 2025
Rapid brain tumor classification from sparse epigenomic data.
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Nature Medicine 31
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March 2025
Lessons from a negative gene therapy trial for Duchenne muscular dystrophy.
Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Borasio, G.D. and Grittner, U.
Nature Medicine 31
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January 2025
2024
Proteomic signatures improve risk prediction for common and rare diseases.
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Nature Medicine 30
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September 2024
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes.
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Nature Medicine 30
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June 2024
Multiomic spatial landscape of innate immune cells at human central nervous system borders.
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Nature Medicine 30
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2023
Body composition and lung cancer-associated cachexia in TRACERx.
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Nature Medicine 29
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April 2023
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx.
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Nature Medicine 29
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April 2023
2022
Drivers and determinants of strain dynamics following fecal microbiota transplantation.
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Nature Medicine 28
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September 2022
Microbiome and metabolome features of the cardiometabolic disease spectrum.
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Nature Medicine 28
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17 February 2022
Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease.
Talmor-Barkan, Y., Bar, N., Shaul, A.A., Shahaf, N., Godneva, A., Bussi, Y., Lotan-Pompan, M., Weinberger, A., Shechter, A., Chezar-Azerrad, C., Arow, Z., Hammer, Y., Chechi, K., Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Fromentin, S., Dumas, M.E., Ehrlich, S.D., Pedersen, O., Kornowski, R. and Segal, E.
Nature Medicine 28
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February 2022
2021
Reporting guidelines for human microbiome research: the STORMS checklist.
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Nature Medicine 27
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November 2021
Mutations and variants of ONECUT1 in diabetes.
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Nature Medicine 27
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November 2021
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Muus, C. ORCID: https://orcid.org/0000-0003-2779-0893, Luecken, M.D. ORCID: https://orcid.org/0000-0001-7464-7921, Eraslan, G., Sikkema, L. ORCID: https://orcid.org/0000-0001-9686-6295, Waghray, A., Heimberg, G., Kobayashi, Y., Vaishnav, E.D. ORCID: https://orcid.org/0000-0003-3720-8051, Subramanian, A. ORCID: https://orcid.org/0000-0002-4134-7612, Smillie, C., Jagadeesh, K.A., Duong, E.T. ORCID: https://orcid.org/0000-0001-7122-4448, Fiskin, E., Triglia, E.T. ORCID: https://orcid.org/0000-0002-6059-0116, Ansari, M. ORCID: https://orcid.org/0000-0002-8819-7965, Cai, P., Lin, B. ORCID: https://orcid.org/0000-0002-8851-3534, Buchanan, J., Chen, S., Shu, J., Haber, A.L., Chung, H., Montoro, D.T., Adams, T., Aliee, H., Allon, S.J., Andrusivova, Z., Angelidis, I., Ashenberg, O., Bassler, K., Bécavin, C., Benhar, I., Bergenstråhle, J., Bergenstråhle, L., Bolt, L., Braun, E., Bui, L.T., Callori, S., Chaffin, M., Chichelnitskiy, E., Chiou, J., Conlon, T.M., Cuoco, M.S., Cuomo, A.S.E., Deprez, M., Duclos, G., Fine, D., Fischer, D.S., Ghazanfar, S., Gillich, A., Giotti, B., Gould, J., Guo, M., Gutierrez, A.J., Habermann, A.C., Harvey, T., He, P., Hou, X., Hu, L., Hu, Y., Jaiswal, A., Ji, L., Jiang, P., Kapellos, T.S., Kuo, C.S., Larsson, L., Leney-Greene, M.A., Lim, K., Litviňuková, M. ORCID: https://orcid.org/0000-0002-6713-3647, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Lukassen, S., Luo, W., Maatz, H., Madissoon, E., Mamanova, L., Manakongtreecheep, K., Leroy, S., Mayr, C.H., Mbano, I.M., McAdams, A.M., Nabhan, A.N., Nyquist, S.K., Penland, L., Poirion, O.B., Poli, S., Qi, C.C., Queen, R., Reichart, D., Rosas, I., Schupp, J.C., Shea, C.V., Shi, X., Sinha, R., Sit, R.V., Slowikowski, K., Slyper, M., Smith, N.P., Sountoulidis, A., Strunz, M., Sullivan, T.B., Sun, D., Talavera-López, C., Tan, P., Tantivit, J., Travaglini, K.J., Tucker, N.R., Vernon, K.A., Wadsworth, M.H., Waldman, J., Wang, X., Xu, K., Yan, W., Zhao, W. and Ziegler, C.G.K.
Nature Medicine 27
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2 March 2021
2020
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes.
Sungnak, W. ORCID: https://orcid.org/0000-0002-0136-4960, Huang, N., Bécavin, C. ORCID: https://orcid.org/0000-0003-1555-3153, Berg, M., Queen, R., Litvinukova, M. ORCID: https://orcid.org/0000-0002-6713-3647, Talavera-López, C., Maatz, H. ORCID: https://orcid.org/0000-0002-9232-6272, Reichart, D., Sampaziotis, F. ORCID: https://orcid.org/0000-0003-0812-7586, Worlock, K.B., Yoshida, M. ORCID: https://orcid.org/0000-0002-3521-5322 and Barnes, J.L.
Nature Medicine 26
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May 2020
2019
A clonal expression biomarker associates with lung cancer mortality.
Biswas, D., Birkbak, N.J. ORCID: https://orcid.org/0000-0003-1613-9587, Rosenthal, R., Hiley, C.T., Lim, E.L., Papp, K. ORCID: https://orcid.org/0000-0003-0619-8233, Boeing, S., Krzystanek, M., Djureinovic, D., La Fleur, L., Greco, M., Döme, B., Fillinger, J., Brunnström, H. ORCID: https://orcid.org/0000-0001-7402-138X, Wu, Y., Moore, D.A., Skrzypski, M., Abbosh, C., Litchfield, K., Al Bakir, M., Watkins, T.B.K. ORCID: https://orcid.org/0000-0001-7414-737X, Veeriah, S., Wilson, G.A., Jamal-Hanjani, M., Moldvay, J., Botling, J., Chinnaiyan, A.M., Micke, P., Hackshaw, A., Bartek, J., Csabai, I., Szallasi, Z., Herrero, J. ORCID: https://orcid.org/0000-0001-7313-717X, McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045 and Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018
Nature Medicine 25
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October 2019
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
Chemi, F., Rothwell, D.G., McGranahan, N., Gulati, S., Abbosh, C., Pearce, S.P. ORCID: https://orcid.org/0000-0002-1680-5538, Zhou, C., Wilson, G.A., Jamal-Hanjani, M., Birkbak, N., Pierce, J., Kim, C.S., Ferdous, S., Burt, D.J., Slane-Tan, D., Gomes, F., Moore, D., Shah, R., Al Bakir, M., Hiley, C., Veeriah, S., Summers, Y., Crosbie, P., Ward, S., Mesquita, B., Dynowski, M., Biswas, D. ORCID: https://orcid.org/0000-0001-9141-5188, Tugwood, J., Blackhall, F., Miller, C., Hackshaw, A., Brady, G. ORCID: https://orcid.org/0000-0002-5009-8814, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018 and Dive, C. ORCID: https://orcid.org/0000-0002-1726-8850
Nature Medicine 25
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October 2019
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi, K., de Massy, M.R. ORCID: https://orcid.org/0000-0002-3048-1680, Ismail, M., Reading, J.L., Uddin, I. ORCID: https://orcid.org/0000-0003-0736-3149, Woolston, A. ORCID: https://orcid.org/0000-0002-8932-2895, Hatipoglu, E., Oakes, T., Rosenthal, R., Peacock, T. ORCID: https://orcid.org/0000-0001-9385-116X, Ronel, T., Noursadeghi, M. ORCID: https://orcid.org/0000-0002-4774-0853, Turati, V., Furness, A.J.S., Georgiou, A., Wong, Y.N.S., Ben Aissa, A., Sunderland, M.W., Jamal-Hanjani, M., Veeriah, S., Birkbak, N.J., Wilson, G.A., Hiley, C.T., Ghorani, E. ORCID: https://orcid.org/0000-0001-5373-5762, Guerra-Assunção, J.A. ORCID: https://orcid.org/0000-0001-6593-403X, Herrero, J. ORCID: https://orcid.org/0000-0001-7313-717X, Enver, T., Hadrup, S.R. ORCID: https://orcid.org/0000-0002-5937-4344, Hackshaw, A., Peggs, K.S., McGranahan, N., Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018, Quezada, S.A. ORCID: https://orcid.org/0000-0002-9763-1700 and Chain, B. ORCID: https://orcid.org/0000-0002-7417-3970
Nature Medicine 25
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October 2019
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation.
Thomas, A.M. ORCID: https://orcid.org/0000-0001-5789-3354, Manghi, P., Asnicar, F. ORCID: https://orcid.org/0000-0003-3732-1468, Pasolli, E., Armanini, F., Zolfo, M. ORCID: https://orcid.org/0000-0001-6661-4046, Beghini, F. ORCID: https://orcid.org/0000-0002-8105-9607, Manara, S., Karcher, N., Pozzi, C., Gandini, S. ORCID: https://orcid.org/0000-0002-1348-4548, Serrano, D., Tarallo, S. ORCID: https://orcid.org/0000-0003-0887-2607, Francavilla, A. ORCID: https://orcid.org/0000-0003-1594-2837, Gallo, G. ORCID: https://orcid.org/0000-0003-1066-4671, Trompetto, M., Ferrero, G. ORCID: https://orcid.org/0000-0002-4580-0680, Mizutani, S., Shiroma, H., Shiba, S., Shibata, T. ORCID: https://orcid.org/0000-0002-0477-210X, Yachida, S., Yamada, T., Wirbel, J. ORCID: https://orcid.org/0000-0002-4073-3562, Schrotz-King, P. ORCID: https://orcid.org/0000-0003-4339-3492, Ulrich, C.M., Brenner, H., Arumugam, M. ORCID: https://orcid.org/0000-0002-0886-9101, Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X, Zeller, G. ORCID: https://orcid.org/0000-0003-1429-7485, Cordero, F., Dias-Neto, E. ORCID: https://orcid.org/0000-0001-5670-8559, Setubal, J.C., Tett, A., Pardini, B. ORCID: https://orcid.org/0000-0001-9571-4257, Rescigno, M., Waldron, L. ORCID: https://orcid.org/0000-0003-2725-0694, Naccarati, A. ORCID: https://orcid.org/0000-0001-5774-0905 and Segata, N. ORCID: https://orcid.org/0000-0002-1583-5794
Nature Medicine 25
(4): 667-678.
April 2019
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer.
Wirbel, J. ORCID: https://orcid.org/0000-0002-4073-3562, Pyl, P.T. ORCID: https://orcid.org/0000-0002-7651-883X, Kartal, E., Zych, K. ORCID: https://orcid.org/0000-0001-7426-0516, Kashani, A., Milanese, A. ORCID: https://orcid.org/0000-0002-7050-2239, Fleck, J.S., Voigt, A.Y., Palleja, A. ORCID: https://orcid.org/0000-0001-5388-4063, Ponnudurai, R., Sunagawa, S. ORCID: https://orcid.org/0000-0003-3065-0314, Coelho, L.P., Schrotz-King, P. ORCID: https://orcid.org/0000-0003-4339-3492, Vogtmann, E., Habermann, N., Niméus, E., Thomas, A.M. ORCID: https://orcid.org/0000-0001-5789-3354, Manghi, P., Gandini, S. ORCID: https://orcid.org/0000-0002-1348-4548, Serrano, D., Mizutani, S., Shiroma, H., Shiba, S., Shibata, T. ORCID: https://orcid.org/0000-0002-0477-210X, Yachida, S., Yamada, T., Waldron, L. ORCID: https://orcid.org/0000-0003-2725-0694, Naccarati, A. ORCID: https://orcid.org/0000-0001-5774-0905, Segata, N. ORCID: https://orcid.org/0000-0002-1583-5794, Sinha, R., Ulrich, C.M., Brenner, H., Arumugam, M. ORCID: https://orcid.org/0000-0002-0886-9101, Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X and Zeller, G. ORCID: https://orcid.org/0000-0003-1429-7485
Nature Medicine 25
(4): 679-689.
April 2019
2018
Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Ruess, D.A. ORCID: https://orcid.org/0000-0003-4371-2246, Heynen, G.J. ORCID: https://orcid.org/0000-0001-7721-5710, Ciecielski, K.J., Ai, J., Berninger, A., Kabacaoglu, D., Görgülü, K. ORCID: https://orcid.org/0000-0002-1613-1422, Dantes, Z., Wörmann, S.M., Diakopoulos, K.N., Karpathaki, A.F., Kowalska, M., Kaya-Aksoy, E., Song, L., Zeeuw van der Laan, E.A. ORCID: https://orcid.org/0000-0002-2784-5236, López-Alberca, M.P., Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330, Reichert, M., Saur, D., Erkan, M.M., Hopt, U.T., Sainz, B., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Schmid, R.M., Lesina, M. and Algül, H.
Nature Medicine 24
(7): 954-960.
July 2018
Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.
Wong, G.S., Zhou, J., Liu, J.B., Wu, Z., Xu, X., Li, T., Xu, D., Schumacher, S.E., Puschhof, J., McFarland, J., Zou, C., Dulak, A., Henderson, L., Xu, P., O'Day, E., Rendak, R., Liao, W.L., Cecchi, F., Hembrough, T., Schwartz, S., Szeto, C., Rustgi, A.K., Wong, K.K., Diehl, J.A. ORCID: https://orcid.org/0000-0001-9854-5049, Jensen, K., Graziano, F., Ruzzo, A., Fereshetian, S., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Carr, S.A. ORCID: https://orcid.org/0000-0002-7203-4299, Beroukhim, R., Nakamura, K., Oki, E., Watanabe, M., Baba, H., Imamura, Y., Catenacci, D. and Bass, A.J.
Nature Medicine 24
(7): 968-977.
July 2018
2017
A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle.
Awazawa, M., Gabel, P., Tsaousidou, E., Nolte, H., Krüger, M., Schmitz, J., Ackermann, P.J., Brandt, C., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Motameny, S., Wunderlich, F.T., Kornfeld, J.W., Blüher, M. and Brüning, J.C.
Nature Medicine 23
(12): 1466-1473.
1 December 2017
2016
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.
Stellos, K., Gatsiou, A., Stamatelopoulos, K., Perisic Matic, L., John, D., Lunella, F.F., Jae, N., Rossbach, O., Amrhein, C., Sigala, F., Boon, R.A., Fuertig, B., Manavski, Y., You, X., Uchida, S., Keller, T., Boeckel, J.N., Franco-Cereceda, A., Maegdefessel, L., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Schwalbe, H., Bindereif, A., Eriksson, P., Hedin, U., Zeiher, A.M. and Dimmeler, S.
Nature Medicine 22
(10): 1140-1150.
October 2016
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Li, S., Garrett-Bakelman, F.E., Chung, S.S., Sanders, M.A., Hricik, T., Rapaport, F., Patel, J., Dillon, R., Vijay, P., Brown, A.L., Perl, A.E., Cannon, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Luger, S., Becker, M., Lewis, I.D., To, L.B., Delwel, R., Löwenberg, B., Döhner, H., Döhner, K., Guzman, M.L., Hassane, D.C., Roboz, G.J., Grimwade, D., Valk, P.J.M., D'Andrea, R.J., Carroll, M., Park, C.Y., Neuberg, D., Levine, R., Melnick, A.M. and Mason, C.E.
Nature Medicine 22
(7): 792-9.
July 2016
2014
Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.
Cui, Y., Niziolek, P.J., MacDonald, B.T., Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Matthes, S., Jacobsen, C.M., Conlon, R.A., Brommage, R., Powell, D.R., He, X., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Williams, B.O., Warman, M.L. and Robling, A.G.
Nature Medicine 20
(11): 1229-1230.
6 November 2014
Altered translation of GATA1 in Diamond-Blackfan anemia.
Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Gazda, H.T., Eng, J.C., Eichhorn, S.W., Thiru, P., Ghazvinian, R., George, T.I., Gotlib, J.R., Beggs, A.H., Sieff, C.A., Lodish, H.F., Lander, E.S. and Sankaran, V.G.
Nature Medicine 20
(7): 748-753.
July 2014
Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma.
Rahal, R., Frick, M., Romero, R., Korn, J.M., Kridel, R., Chun Chan, F., Meissner, B., Bhang, H.E., Ruddy, D., Kauffmann, A., Farsidjani, A., Derti, A., Rakiec, D., Naylor, T., Pfister, E., Kovats, S., Kim, S., Dietze, K., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Steidl, C., Tzankov, A., Hummel, M., Monahan, J., Morrissey, M.P., Fritsch, C., Sellers, W.R., Cooke, V.G., Gascoyne, R.D., Lenz, G. and Stegmeier, F.
Nature Medicine 20
(1): 87-92.
January 2014
2013
High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann, C., Heemskerk, B., Kvistborg, P., Kluin, R.J.C., Bolotin, D.A., Chen, X. ORCID: https://orcid.org/0000-0002-5614-1406, Bresser, K., Nieuwland, M., Schotte, R., Michels, S., Gomez-Eerland, R., Jahn, L., Hombrink, P., Legrand, N., Shu, C.J., Mamedov, I.Z., Velds, A., Blank, C.U., Haanen, J.B.A.G., Turchaninova, M.A., Kerkhoven, R.M., Spits, H., Hadrup, S.R., Heemskerk, M.H.M., Blankenstein, T., Chudakov, D.M., Bendle, G.M. and Schumacher, T.N.M.
Nature Medicine 19
(11): 1534-1541.
November 2013
Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis.
Noti, M., Wojno, E.D.T., Kim, B.S., Siracusa, M.C., Giacomin, P.R., Nair, M.G., Benitez, A.J., Ruymann, K.R., Muir, A.B., Hill, D.A., Chikwava, K.R., Moghaddam, A.E., Sattentau, Q.J. ORCID: https://orcid.org/0000-0001-7170-1937, Alex, A., Zhou, C., Yearley, J.H., Menard-Katcher, P., Kubo, M., Obata-Ninomiya, K., Karasuyama, H., Comeau, M.R., Brown-Whitehorn, T., de Waal Malefyt, R., Sleiman, P.M., Hakonarson, H., Cianferoni, A., Falk, G.W., Wang, M.L., Spergel, J.M. and Artis, D.
Nature Medicine 19
(8): 1005-1013.
August 2013
2012
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline.
Vom Berg, J., Prokop, S., Miller, K.R., Obst, J., Kaelin, R.E., Lopategui-Cabezas, I., Wegner, A., Mair, F., Schipke, C.G. ORCID: https://orcid.org/0000-0002-1105-1853, Peters, O. ORCID: https://orcid.org/0000-0003-0568-2998, Winter, Y., Becher, B. and Heppner, F.L.
Nature Medicine 18
(12): 1812-1819.
December 2012
Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1.
Stock, K., Kumar, J., Synowitz, M., Petrosino, S., Imperatore, R., Smith, E.S.J. ORCID: https://orcid.org/0000-0002-2699-1979, Wend, P., Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Nuber, U.A., Gurok, U., Matyash, V., Waelzlein, J.H., Chirasani, S.R., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Cravatt, B.F., Momma, S., Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352, Ligresti, A., De Petrocellis, L., Cristino, L., Di Marzo, V., Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Glass, R.
Nature Medicine 18
(8): 1232-1238.
August 2012
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.
Guo, W., Schafer, S., Greaser, M.L., Radke, M.H. ORCID: https://orcid.org/0000-0003-0112-9917, Liss, M. ORCID: https://orcid.org/0000-0002-0585-7850, Govindarajan, T., Maatz, H. ORCID: https://orcid.org/0000-0002-9232-6272, Schulz, H. ORCID: https://orcid.org/0000-0002-0226-964X, Lincoln, S.E., Parrish, A.M., Dauksaite, V. ORCID: https://orcid.org/0000-0002-9399-4731, Vakeel, P., Klaassen, S. ORCID: https://orcid.org/0000-0001-5925-9912, Gerull, B. ORCID: https://orcid.org/0000-0002-1363-8826, Thierfelder, L., Regitz-Zagrosek, V., Hacker, T.A., Saupe, K.W., Dec, G.W., Ellinor, P.T., MacRae, C.A., Spallek, B., Fischer, R. ORCID: https://orcid.org/0000-0002-4828-2882, Perrot, A. ORCID: https://orcid.org/0000-0002-8800-342X, Ozcelik, C., Saar, K. ORCID: https://orcid.org/0000-0002-4483-1557, Hubner, N. ORCID: https://orcid.org/0000-0002-1218-6223 and Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172
Nature Medicine 18
(5): 766-773.
May 2012
2011
Lrp5 functions in bone to regulate bone mass.
Cui, Y., Niziolek, P.J., Macdonald, B.T., Zylstra, C.R., Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Robinson, D.R., Zhong, Z., Matthes, S., Jacobsen, C.M., Conlon, R.A., Brommage, R., Liu, Q., Mseeh, F., Powell, D.R., Yang, Q.M., Zambrowicz, B., Gerrits, H., Gossen, J.A., He, X., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Williams, B.O., Warman, M.L. and Robling, A.G.
Nature Medicine 17
(6): 684-691.
June 2011
The Ngal reporter mouse detects the response of the kidney to injury in real time.
Paragas, N., Qiu, A., Zhang, Q., Samstein, B., Deng, S.X., Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142, Viltard, M., Yu, W., Forster, C.S., Gong, G., Liu, Y., Kulkarni, R., Mori, K., Kalandadze, A., Ratner, A.J., Devarajan, P., Landry, D.W., D'Agati, V., Lin, C.S. and Barasch, J.
Nature Medicine 17
(2): 216-222.
February 2011
2010
Transgenic mice with a diverse human T cell antigen receptor repertoire.
Li, L.P., Lampert, J.C., Chen, X. ORCID: https://orcid.org/0000-0002-5614-1406, Leitao, C., Popovic, J., Mueller, W. and Blankenstein, T.
Nature Medicine 16
(9): 1029-1034.
September 2010
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.
Bendle, G.M., Linnemann, C., Hooijkaas, A.I., Bies, L., de Witte, M.A., Jorritsma, A., Kaiser, A.D.M., Pouw, N., Debets, R., Kieback, E. ORCID: https://orcid.org/0000-0003-3831-2846, Uckert, W., Song, J.Y., Haanen, J.B.A.G. and Schumacher, T.N.M.
Nature Medicine 16
(5): 565-570, 1p following 570.
May 2010
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B., Walter, K., Kreher, S., Kumar, R., Hummel, M., Lenze, D., Koechert, K. ORCID: https://orcid.org/0000-0002-5548-2022, Bouhlel, M.A., Richter, J., Soler, E., Stadhouders, R., Joehrens, K., Wurster, K.D., Callen, D.F., Harte, M.F., Giefing, M., Barlow, R., Stein, H., Anagnostopoulos, I., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Cockerill, P.N., Siebert, R., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Bonifer, C. and Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413
Nature Medicine 16
(5): 571-579, 1p following 579.
May 2010
2009
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis.
Roepke, T.K., King, E.C., Reyna-Neyra, A., Paroder, M., Purtell, K., Koba, W., Fine, E., Lerner, D.J., Carrasco, N. and Abbott, G.W.
Nature Medicine 15
(10): 1186-1194.
October 2009
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system.
Schulze-Topphoff, U., Prat, A., Prozorovski, T., Siffrin, V. ORCID: https://orcid.org/0000-0002-1532-2868, Paterka, M., Herz, J., Bendix, I. ORCID: https://orcid.org/0000-0002-9751-3640, Ifergan, I., Schadock, I., Mori, M.A., Van Horssen, J., Schroeter, F., Smorodchenko, A., Han, M.H., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Steinman, L., Aktas, O. ORCID: https://orcid.org/0000-0002-2020-9210 and Zipp, F. ORCID: https://orcid.org/0000-0002-1231-1928
Nature Medicine 15
(7): 788-793.
July 2009
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
Machnik, A., Neuhofer, W., Jantsch, J., Dahlmann, A., Tammela, T., Machura, K., Park, J.K., Beck, F.X., Mueller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Derer, W., Goss, J., Ziomber, A., Dietsch, P., Wagner, H., van Rooijen, N., Kurtz, A., Hilgers, K.F., Alitalo, K., Eckardt, K.U., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199, Kerjaschki, D. and Titze, J.
Nature Medicine 15
(5): 545-552.
May 2009
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Arlt, F., Schwabe, H., Smith, J., Fichtner, I., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Schlag, P.M.
Nature Medicine 15
(1): 59-67.
January 2009
2008
Angiogenesis factors and preeclampsia.
Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080 and Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199
Nature Medicine 14
(11): 1187-1188.
November 2008
Aggravation of viral hepatitis by platelet-derived serotonin.
Lang, P.A., Contaldo, C., Georgiev, P., El-Badry, A.M., Recher, M., Kurrer, M., Cervantes-Barragan, L., Ludewig, B., Calzascia, T., Bolinger, B., Merkler, D., Odermatt, B., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Graf, R., Clavien, P.A., Hegazy, A.N., Loehning, M., Harris, N.L., Ohashi, P.S., Hengartner, H., Zinkernagel, R.M. and Lang, K.S.
Nature Medicine 14
(7): 756-761.
July 2008
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Jones, C.A., London, N.R., Chen, H. ORCID: https://orcid.org/0000-0003-0676-4610, Park, K.W. ORCID: https://orcid.org/0000-0003-2771-249X, Sauvaget, D., Stockton, R.A., Wythe, J.D., Suh, W., Larrieu-Lahargue, F., Mukouyama, Y.S. ORCID: https://orcid.org/0000-0002-9084-4922, Lindblom, P., Seth, P., Frias, A., Nishiya, N., Ginsberg, M.H., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Zhang, K. and Li, D.Y.
Nature Medicine 14
(4): 448-453.
April 2008
Protein kinase CK2 links extracellular growth factor signaling with the control of p27(Kip1) stability in the heart.
Hauck, L., Harms, C., An, J., Rohne, J., Gertz, K., Endres, M., Dietz, R. and von Harsdorf, R.
Nature Medicine 14
(3): 315-324.
March 2008
2006
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis.
Schuchmann, S., Schmitz, D. ORCID: https://orcid.org/0000-0003-2741-5241, Rivera, C., Vanhatalo, S., Salmen, B., Mackie, K., Sipilae, S.T., Voipio, J. and Kaila, K.
Nature Medicine 12
(7): 817-823.
July 2006
2002
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning.
Faendrich, F., Lin, X., Chai, G.X., Schulze, M., Ganten, D., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Holle, J., Huang, D.S., Parwaresch, R., Zavazava, N. and Binas, B.
Nature Medicine 8
: 171-178.
1 February 2002
2001
Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment.
Priller, J., Fluegel, A., Wehner, T., Boentert, M., Haas, C.A., Prinz, M., Fernandez-Klett, F., Prass, K., Bechmann, I., de Boer, B.A., Frotscher, M., Kreutzberg, G.W., Persons, D.A. and Dirnagl, U.
Nature Medicine 7
(12): 1356-1361.
1 December 2001
Adoptive tumor therapy with T lymphocytes enriched through an IFN-gamma capture assay.
Becker, C., Pohla, H., Frankenberger, B., Schueler, T., Assenmacher, M., Schendel, D.J. and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Nature Medicine 7
(10): 1159-1162.
1 January 2001
2000
Genetic analysis of chemoresistance in primary murine lymphomas.
Schmitt, C.A., Rosenthal, C.T. and Lowe, S.W.
Nature Medicine 6
: 1029-1035.
1 September 2000
1998
B cells inhibit induction of T cell-dependent tumor immunity.
Qin, Z.H., Richter, G., Schueler, T., Ibe, S., Cao, X.T. and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Nature Medicine 4
: 627-630.
1 January 1998
The site-specific correction of genetic defects.
Strauss, M.
Nature Medicine 4
: 274-275.
1 January 1998
1997
Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression.
Bargou, R.C., Juerchott, K., Wagener, C., Bergmann, S., Metzner, S., Bommert, K., Mapara, M.Y., Winzer, K.J., Dietel, M., Doerken, B. and Royer, H.D.
Nature Medicine 3
: 447-450.
1 January 1997
Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death.
Sandig, V., Brand, K., Herwig, S., Lukas, J., Bartek, J. and Strauss, M.
Nature Medicine 3
: 313-319.
1 January 1997
1995
Unrestricted cell cycling and cancer.
Strauss, M., Lukas, J. and Bartek, J.
Nature Medicine 1
(12): 1245-1246.
December 1995
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