2022

Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath, J., Du, W., Pruene, A., Braun, T., Thommandru, B., Turk, R., Sturgeon, M.L., Kurgan, G.L., Amini, L., Stein, M., Zittel, T., Martini, S., Ostendorf, L., Wilhelm, A., Akyüz, L., Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950, Hoepken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Pruß, A., Künkele, A., Jacobi, A.M., Volk, H.D., Schmueck-Henneresse, M., Stripecke, R., Reinke, P. and Wagner, D.L.
Molecular Therapy - Methods and Clinical Development 25 : 311-330. 9 June 2022

Accelerating clinical scale production of BCMA CAR T cells with defined maturation stages.
Joedicke, J.J. ORCID: https://orcid.org/0000-0002-4708-3216, Großkinsky, U., Gerlach, K., Künkele, A., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Molecular Therapy - Methods and Clinical Development 24 : 181-198. 10 March 2022

Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors.
Li, C., Wang, H., Gil, S., Germond, A., Fountain, C., Baldessari, A., Kim, J. ORCID: https://orcid.org/0000-0001-5301-8130, Liu, Z., Georgakopoulou, A. ORCID: https://orcid.org/0000-0003-1541-7549, Radtke, S., Raskó, T., Pande, A. ORCID: https://orcid.org/0009-0008-0826-973X, Chiang, C., Chin, E. ORCID: https://orcid.org/0000-0003-0888-5213, Yannaki, E. ORCID: https://orcid.org/0000-0002-9849-1279, Izsvak, Z. ORCID: https://orcid.org/0000-0002-2053-2384, Papayannopoulou, T. ORCID: https://orcid.org/0000-0002-4523-1393, Kiem, H.P. ORCID: https://orcid.org/0000-0001-5949-4947 and Lieber, A. ORCID: https://orcid.org/0000-0001-6742-6266
Molecular Therapy - Methods and Clinical Development 24 : 127-141. 10 March 2022

2021

Characterization and modulation of anti- αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Kierkels, G.J.J., van Diest, E., Hernández-López, P., Scheper, W., de Bruin, A.C.M., Frijlink, E., Aarts-Riemens, T., van Dooremalen, S.F.J., Beringer, D.X., Oostvogels, R., Kramer, L., Straetemans, T., Uckert, W., Sebestyén, Z. and Kuball, J.
Molecular Therapy - Methods and Clinical Development 22 (10): 388-400. 10 September 2021

2019

Preclinical evaluation of a cell-based gene therapy using the Sleeping Beauty transposon system in choroidal neovascularization.
Hernandez, M., Recalde, S., Garcia-Garcia, L., Bezunartea, J., Miskey, C. ORCID: https://orcid.org/0000-0002-7566-9556, Johnen, S., Diarra, S., Sebe, A., Rodriguez-Madoz, J.R., Pouillot, S., Marie, C., Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384, Scherman, D., Kropp, M., Prosper, F., Thumann, G., Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658, Garcia-Layana, A. and Fernandez-Robredo, P.
Molecular Therapy - Methods and Clinical Development 15 : 403-417. 13 December 2019

2018

Integrating HDAd5/35++ vectors as a new platform for HSC gene therapy of hemoglobinopathies.
Li, C., Psatha, N., Wang, H., Singh, M. ORCID: https://orcid.org/0000-0002-8626-5418, Samal, H.B., Zhang, W., Ehrhardt, A., Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384, Papayannopoulou, T. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 9 : 142-152. 15 June 2018

A combined in vivo HSC transduction/selection approach results in efficient and stable gene expression in peripheral blood cells in mice.
Wang, H., Richter, M., Psatha, N., Li, C., Kim, J., Liu, J., Ehrhardt, A., Nilsson, S.K., Cao, B., Palmer, D., Ng, P., Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384, Haworth, K.G., Kiem, H.P., Papayannopoulou, T. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 8 : 52-64. 16 March 2018