Browse by Journal Title

2022

Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath, J. and Du, W. and Pruene, A. and Braun, T. and Thommandru, B. and Turk, R. and Sturgeon, M.L. and Kurgan, G.L. and Amini, L. and Stein, M. and Zittel, T. and Martini, S. and Ostendorf, L. and Wilhelm, A. and Akyüz, L. and Rehm, A. and Hoepken, U.E. and Pruß, A. and Künkele, A. and Jacobi, A.M. and Volk, H.D. and Schmueck-Henneresse, M. and Stripecke, R. and Reinke, P. and Wagner, D.L.
Molecular Therapy - Methods and Clinical Development 25 : 311-330. 9 June 2022

Accelerating clinical scale production of BCMA CAR T cells with defined maturation stages.
Joedicke, J.J. and Großkinsky, U. and Gerlach, K. and Künkele, A. and Höpken, U.E. and Rehm, A.
Molecular Therapy - Methods and Clinical Development 24 : 181-198. 10 March 2022

Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors.
Li, C. and Wang, H. and Gil, S. and Germond, A. and Fountain, C. and Baldessari, A. and Kim, J. and Liu, Z. and Georgakopoulou, A. and Radtke, S. and Raskó, T. and Pande, A. and Chiang, C. and Chin, E. and Yannaki, E. and Izsvak, Z. and Papayannopoulou, T. and Kiem, H.P. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 24 : 127-141. 10 March 2022

2021

Characterization and modulation of anti- αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Kierkels, G.J.J. and van Diest, E. and Hernández-López, P. and Scheper, W. and de Bruin, A.C.M. and Frijlink, E. and Aarts-Riemens, T. and van Dooremalen, S.F.J. and Beringer, D.X. and Oostvogels, R. and Kramer, L. and Straetemans, T. and Uckert, W. and Sebestyén, Z. and Kuball, J.
Molecular Therapy - Methods and Clinical Development 22 (10): 388-400. 10 September 2021

2019

Preclinical evaluation of a cell-based gene therapy using the Sleeping Beauty transposon system in choroidal neovascularization.
Hernandez, M. and Recalde, S. and Garcia-Garcia, L. and Bezunartea, J. and Miskey, C. and Johnen, S. and Diarra, S. and Sebe, A. and Rodriguez-Madoz, J.R. and Pouillot, S. and Marie, C. and Izsvák, Z. and Scherman, D. and Kropp, M. and Prosper, F. and Thumann, G. and Ivics, Z. and Garcia-Layana, A. and Fernandez-Robredo, P.
Molecular Therapy - Methods and Clinical Development 15 : 403-417. 13 December 2019

2018

Integrating HDAd5/35++ vectors as a new platform for HSC gene therapy of hemoglobinopathies.
Li, C. and Psatha, N. and Wang, H. and Singh, M. and Samal, H.B. and Zhang, W. and Ehrhardt, A. and Izsvák, Z. and Papayannopoulou, T. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 9 : 142-152. 15 June 2018

A combined in vivo HSC transduction/selection approach results in efficient and stable gene expression in peripheral blood cells in mice.
Wang, H. and Richter, M. and Psatha, N. and Li, C. and Kim, J. and Liu, J. and Ehrhardt, A. and Nilsson, S.K. and Cao, B. and Palmer, D. and Ng, P. and Izsvák, Z. and Haworth, K.G. and Kiem, H.P. and Papayannopoulou, T. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 8 : 52-64. 16 March 2018