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Article

Titin's cardiac-specific N2B element is critical to mechanotransduction during volume overload of the heart.
Strom, J. and Bull, M. and Gohlke, J. and Saripalli, C. and Methawasin, M. and Gotthardt, M. and Granzier, H.
Journal of Molecular and Cellular Cardiology 10 April 2024 (In Press)

Nonsense mediated decay factor UPF3B is associated with cMyBP-C haploinsufficiency in hypertrophic cardiomyopathy patients.
Burkart, V. and Kowalski, K. and Disch, A. and Hilfiker-Kleiner, D. and Lal, S. and Dos Remedios, C. and Perrot, A. and Zeug, A. and Ponimaskin, E. and Kosanke, M. and Dittrich-Breiholz, O. and Kraft, T. and Montag, J.
Journal of Molecular and Cellular Cardiology 185 : 26-37. December 2023

Remodeling of substrate consumption in the murine sTAC model of heart failure.
Turer, A. and Altamirano, F. and Schiattarella, G. and May, H. and Gillette, T.G. and Malloy, C.R. and Merritt, M.E.
Journal of Molecular and Cellular Cardiology 134 : 144-153. September 2019

Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N. and Perret, M.F. and Glaser, S.F. and Seeger, T. and Heumüller, A.W. and Chen, W. and John, D. and Kokot, K.E. and Katus, H.A. and Haas, J. and Lackner, M.K. and Kayvanpour, E. and Grabe, N. and Dieterich, C. and von Haehling, S. and Ebner, N. and Hünecke, S. and Leuschner, F. and Fichtlscherer, S. and Meder, B. and Zeiher, A.M. and Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126 : 13-22. January 2019

Polycystin-2-dependent control of cardiomyocyte autophagy.
Criollo, A. and Altamirano, F. and Pedrozo, Z. and Schiattarella, G.G. and Li, D.L. and Rivera-Mejías, P. and Sotomayor-Flores, C. and Parra, V. and Villalobos, E. and Battiprolu, P.K. and Jiang, N. and May, H.I. and Morselli, E. and Somlo, S. and de Smedt, H. and Gillette, T.G. and Lavandero, S. and Hill, J.A.
Journal of Molecular and Cellular Cardiology 118 : 110-121. May 2018

Long noncoding RNA lISPR1 is required for S1P signaling and endothelial cell function.
Josipovic, I. and Pflueger, B. and Fork, C. and Vasconez, A.E. and Oo, J.A. and Hitzel, J. and Seredinski, S. and Gamen, E. and Heringdorf, D.M.Z. and Chen, W. and Looso, M. and Pullamsetti, S.S. and Brandes, R.P. and Leisegang, M.S.
Journal of Molecular and Cellular Cardiology 116 : 57-68. March 2018

Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Streckfuss-Boemeke, K. and Tiburcy, M. and Fomin, A. and Luo, X. and Li, W. and Fischer, C. and Oezcelik, C. and Perrot, A. and Sossalla, S. and Haas, J. and Vidal, R.O. and Rebs, S. and Khadjeh, S. and Meder, B. and Bonn, S. and Linke, W.A. and Zimmermann, W.H. and Hasenfuss, G. and Guan, K.
Journal of Molecular and Cellular Cardiology 113 : 9-21. December 2017

Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.
Siede, D. and Rapti, K. and Gorska, A.A. and Katus, H.A. and Altmüller, J. and Boeckel, J.N. and Meder, B. and Maack, C. and Völkers, M. and Müller, O.J. and Backs, J. and Dieterich, C.
Journal of Molecular and Cellular Cardiology 109 : 48-56. August 2017

Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Magarin, M. and Pohl, T. and Lill, A. and Schulz, H. and Blaschke, F. and Heuser, A. and Thierfelder, L. and Donath, S. and Drenckhahn, J.D.
Journal of Molecular and Cellular Cardiology 97 : 1-14. August 2016

Nuclear translocation of the cardiac L-type calcium channel C-terminus is regulated by sex and 17β-estradiol.
Mahmoodzadeh, S. and Haase, H. and Sporbert, A. and Rharass, T. and Panáková, D. and Morano, I.
Journal of Molecular and Cellular Cardiology 97 : 226-234. August 2016

Therapeutic targeting of autophagy in cardiovascular disease.
Schiattarella, G.G. and Hill, J.A.
Journal of Molecular and Cellular Cardiology 95 : 86-93. June 2016

Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation.
Hirt, M.N. and Boeddinghaus, J. and Mitchell, A. and Schaaf, S. and Boernchen, C. and Müller, C. and Schulz, H. and Hubner, N. and Stenzig, J. and Stoehr, A. and Neuber, C. and Eder, A. and Luther, P.K. and Hansen, A. and Eschenhagen, T.
Journal of Molecular and Cellular Cardiology 74 : 151-161. September 2014

Titin based viscosity in ventricular physiology: An integrative investigation of PEVK-actin interactions.
Chung, C.S. and Methawasin, M. and Nelson, O.L. and Radke, M.H. and Hidalgo, C.G. and Gotthardt, M. and Granzier, H.L.
Journal of Molecular and Cellular Cardiology 51 (3): 428-434. September 2011

Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region deficient mice.
Lee, E.J. and Peng, J. and Radke, M. and Gotthardt, M. and Granzier, H.L.
Journal of Molecular and Cellular Cardiology 49 (3): 449-458. September 2010

Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffness.
Hudson, B.D. and Hidalgo, C.G. and Gotthardt, M. and Granzier, H.L.
Journal of Molecular and Cellular Cardiology 48 (5): 972-978. May 2010

Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease.
Gramlich, M. and Michely, B. and Krohne, C. and Heuser, A. and Erdmann, B. and Klaassen, S. and Hudson, B. and Magarin, M. and Kirchner, F. and Todiras, M. and Granzier, H. and Labeit, S. and Thierfelder, L. and Gerull, B.
Journal of Molecular and Cellular Cardiology 47 (3): 352-358. September 2009

Interaction between autoantibodies against the beta(1)-adrenoceptor and isoprenaline in enhancing L-type Ca(2+) current in rat ventricular myocytes.
Christ, T. and Schindelhauer, S. and Wettwer, E. and Wallukat, G. and Ravens, U.
Journal of Molecular and Cellular Cardiology 41 (4): 716-723. October 2006

Prevention of cardiac remodeling after myocardial infarction in transgenic rats deficient in brain angiotensinogen.
Lal, A. and Veinot, J.P. and Ganten, D. and Leenen, F.H.H.
Journal of Molecular and Cellular Cardiology 39 (3): 521-529. 1 January 2005

Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3beta and transcription factor beta-catenin.
Bergmann, M.W. and Rechner, C. and Freund, C. and Baurand, A. and El Jamali, A. and Dietz, R.
Journal of Molecular and Cellular Cardiology 37 (3): 681-690. 1 January 2004

The L-type Ca2+ channel subunits alpha1c and beta2 are not downregulated in atrial myocardium of patients with chronic atrial fibrillation.
Schotten, U. and Haase, H. and Frechen, D. and Greiser, M. and Stellbrink, C. and Vazguez-Jimenez, J.F. and Morano, I. and Allessie, M.A. and Hanrath, P.
Journal of Molecular and Cellular Cardiology 35 (5): 437-443. May 2003

Role of the local renin-angiotensin system in cardiac damage: a minireview focussing on transgenic animal models.
Bader, M.
Journal of Molecular and Cellular Cardiology 34 (11): 1455-1462. November 2002

Evidence for calcineurin-mediated regulation of SERCA 2a activity in human myocardium.
Muench, G. and Boelck, B. and Karczewski, P. and Schwinger, R.H.G.
Journal of Molecular and Cellular Cardiology 34 (3): 321-334. 1 January 2002

Effect of NF-kappa B inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes.
Bergmann, M.W. and Loeser, P. and Dietz, R. and von Harsdorf, R.
Journal of Molecular and Cellular Cardiology 33 : 1223-1232. 1 January 2001

Autoantibodies against the beta 1-adrenoceptor from patients with dilated cardiomyopathy prolong action potential duration and enhance contractility in isolated cardiomyocytes.
Christ, T. and Wettwer, E. and Dobrev, D. and Adolph, E. and Knaut, M. and Wallukat, G. and Ravens, U.
Journal of Molecular and Cellular Cardiology 33 (8): 1515-1525. 1 January 2001

Professor Albert Wollenberger - In memoriam.
Krause, E.G. and Schulze, W. and Wallukat, G.
Journal of Molecular and Cellular Cardiology 33 : 1-2. 1 January 2001

Phosphorylation of phospholamban at threonine-17 in the absence and presence of beta-adrenergic stimulation in neonatal rat cardiomyocytes.
Bartel, S. and Vetter, D. and Schlegel, W.P. and Wallukat, G. and Krause, E.G. and Karczewski, P.
Journal of Molecular and Cellular Cardiology 32 (12): 2173-2185. 1 January 2000

Reduced Ca2+-sensitivity of SERCA 2a in failing human myocardium due to reduced serin-16 phospholamban phosphorylation.
Schwinger, R.H.G. and Muench, G. and Boelck, B. and Karczewski, P. and Krause, E.G. and Erdmann, E.
Journal of Molecular and Cellular Cardiology 31 (3): 479-491. 1 March 1999

Decreased susceptibility of contractile function to hypoxia/reoxygenation in chronic infarcted rat hearts.
Wagner, K.D. and Geil, D. and Schimke, I. and Stauss, H.M. and Lammerich, A. and Theres, H. and Pfitzer, G. and Vetter, R. and Guenther, J.
Journal of Molecular and Cellular Cardiology 30 : 2341-2353. 1 November 1998

Immunocytochemical localization of the G-protein sub-unit, Goalpha in rat heart. Implications for a role of Goalpha in secretion of cardiac hormones.
Wolf, W.P. and Spicher, K. and Haase, H. and Schulze, W.
Journal of Molecular and Cellular Cardiology 30 : 1149-1162. 1 January 1998

Changes in essential myosin light chain isoform expression provide a molecular basis for isometric force regulation in the failing human heart.
Morano, I. and Haedicke, K. and Haase, H. and Boehm, M. and Erdmann, E. and Schaub, M.C.
Journal of Molecular and Cellular Cardiology 29 (4): 1177-1187. April 1997

Altered expression of PDE1 and PDE4 cyclic nucleotide phosphodiesterase isoforms in 7-oxo-prostacyclin-preconditioned rat heart.
Kostic, M.M. and Erdogan, S. and Rena, G. and Borchert, G. and Hoch, B. and Bartel, S. and Scotland, G. and Huston, E. and Houslay, M. and Krause, E.G.
Journal of Molecular and Cellular Cardiology 29 : 3135-3146. 1 January 1997

Expression of sense and naturally occurring antisense mrna of myosin heavy chain in rat heart tissue and cultivated cardiomyocytes.
Luther, H.P. and Morwinski, R. and Wallukat, G. and Haase, H. and Morano, I.
Journal of Molecular and Cellular Cardiology 29 : 27-35. 1 January 1997

Reciprocal changes in the postnatal expression of the sarcolemmal Na+-Ca2+-exchanger and SERCA2 in rat heart.
Vetter, R. and Studer, R. and Reinecke, H. and Kolar, F. and Ostadalova, I. and Drexler, H.
Journal of Molecular and Cellular Cardiology 27 (8): 1689-1701. 1 August 1995

Functional epitope analysis of the second extracellular loop of the human heart muscarinic acetylcholine receptor.
Fu, M.L.X. and Schulze, W. and Wallukat, G. and Hjalmarson, A. and Hoebeke, J.
Journal of Molecular and Cellular Cardiology 27 : 427-436. 1 January 1995

Interaction of beta-adrenoceptor and adenosine receptor agonists on phosphorylation. Identification of target proteins in mammalian ventricles.
Neumann, J. and Gupta, R.C. and Jones, L.R. and Bodor, G.S. and Bartel, S. and Krause, E.G. and Pask, H.T. and Schmitz, W. and Scholz, H. and Watanabe, A.M.
Journal of Molecular and Cellular Cardiology 27 (8): 1655-1667. 1 January 1995

Localization of muscarinic receptors in human heart biopsies using rabbit anti-peptide antibodies.
Schulze, W. and Fu, M.L.X. and Hoebeke, J. and Hjalmarson, A.
Journal of Molecular and Cellular Cardiology 27 : 1757-1764. 1 January 1995

Anti-beta1-adrenoceptor autoantibodies with chronotropic activity from the serum of patients with dilated cardiomyopathy: mapping ofepitopes in the first and second extracellular loops.
Wallukat, G. and Wollenberger, A. and Morwinski, R. and Pitschner, H.F.
Journal of Molecular and Cellular Cardiology 27 (1): 397-406. 1 January 1995

Titin, myosin light chains, and c-protein in the developing and failing human heart.
Morano, I. and Haedicke, K. and Grom, S. and Koch, A. and Schwinger, R.H.G. and Boehm, M. and Bartel, S. and Erdmann, E. and Krause, E.G.
Journal of Molecular and Cellular Cardiology 26 (3): 361-368. 1 March 1994

Cardiac troponin I and tension generation of skinned fibres in the developing rat heart.
Bartel, S. and Morano, I. and Hunger, H.D. and Katus, H. and Pask, H. and Karczewski, P. and Krause, E.G.
Journal of Molecular and Cellular Cardiology 26 : 1123-1131. 1 January 1994

Selective activation of cardiac angiotensinogen gene expression in post-infarction ventricular remodeling in the rat.
Lindpaintner, K. and Lu, W. and Niedermaier, N. and Schieffer, B. and Just, H. and Ganten, D. and Drexler, H.
Journal of Molecular and Cellular Cardiology 25 (2): 133-143. February 1993

Correlation of myosin heavy chain expression in the rat with cAMP in different models of hypertension-induced cardiac hypertrophy.
Morano, I. and Adler, K. and Weismann, K. and Knorr, A. and Erdmann, E. and Boehm, M.
Journal of Molecular and Cellular Cardiology 25 : 387-394. 1 January 1993

Letter

Up next: the dawn of systems biology in HFpEF research.
Bode, D. and Sotomayor-Flores, C. and Schiattarella, G.G.
Journal of Molecular and Cellular Cardiology 168 : 96-97. July 2022

"MLP: A Stress Sensor Goes Nuclear" By Sylvia Gunkel, Joerg Heineke, Denise Hilfiker-Kleiner, Ralph Knoell, J Mol Cell Cardiol. 2009;47(4):423-5.
Gehmlich, K. and Ehler, E. and Perrot, A. and Fuerst, D.O. and Geier, C.
Journal of Molecular and Cellular Cardiology 48 (2): 424-425. February 2010

Editorial

Metabolism and inflammation in cardiovascular health and diseases: mechanisms to therapies.
Schiattarella, G.G. and Wang, Y. and Tian, R. and Hill, J.A.
Journal of Molecular and Cellular Cardiology 157 : 113-114. August 2021

"To erb-B or not to erb-B..." Neuregulin-1/ErbB signaling in heart development and function.
Garratt, A.N.
Journal of Molecular and Cellular Cardiology 41 (2): 215-218. August 2006