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Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase in B cell lymphomas.
Lopez, C. and Schleussner, N. and Bernhart, S.H. and Kleinheinz, K. and Sungalee, S. and Sczakiel, H.L. and Kretzmer, H. and Toprak, U.H. and Glaser, S. and Wagener, R. and Ammerpohl, O. and Bens, S. and Giefing, M. and Sanchez, J.C.G. and Apic, G. and Hubschmann, D. and Janz, M. and Kreuz, M. and Mottok, A. and Müller, J.M. and Seufert, J. and Hoffmann, S. and Korbel, J.O. and Russell, R.B. and Schule, R. and Trumper, L. and Klapper, W. and Radlwimmer, B. and Lichter, P. and Kuppers, R. and Schlesner, M. and Mathas, S. and Siebert, R.
Haematologica 28 April 2022 (In Press)

CHIP-related epigenetic age acceleration correlates with CHIP clone size in patients with high morbidity.
Feldkamp, J.D. and Vetter, V.M. and Arends, C.M. and Lang, T.J.L. and Bullinger, L. and Damm, F. and Demuth, I. and Frick, M.
Haematologica 3 March 2022 (In Press)

B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
Schmid, V.K. and Khadour, A. and Ahmed, N. and Brandl, C. and Nitschke, L. and Rajewsky, K. and Jumaa, H. and Hobeika, E.
Haematologica 13 January 2022 (In Press)

Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways.
Braun, T. and Glass, M. and Wahnschaffe, L. and Otte, M. and Mayer, P. and Franitza, M. and Altmüller, J. and Hallek, M. and Hüttelmaier, S. and Schrader, A. and Herling, M.
Haematologica 107 (1): 187-200. January 2022


The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S. and Cabantog, A. and MacPhee, L. and Im, J. and Ruess, C. and Demir, B. and Sperb, N. and Rücker, F.G. and Döhner, K. and Herold, T. and Pollack, J.R. and Bullinger, L. and Rouhi, A. and Kuchenbauer, F.
Haematologica 2 December 2021 (In Press)

Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide - an international collaborative study.
Kayser, S. and Schlenk, R.F. and Lebon, D. and Carre, M. and Götze, K.S. and Stölzel, F. and Berceanu, A. and Schäfer-Eckart, K. and Peterlin, P. and Hicheri, Y. and Rahme, R. and Raffoux, E. and Chermat, F. and Krause, S.W. and Aulitzky, W.E. and Rigaudeau, S. and Noppeney, R. and Berthon, C. and Görner, M. and Jost, E. and Carassou, P. and Keller, U. and Orvain, C. and Braun, T. and Saillard, C. and Arar, A. and Kunzmann, V. and Wemeau, M. and De Wit, M. and Niemann, D. and Bonmati, C. and Schwänen, C. and Abraham, J. and Aljijakli, A. and Haiat, S. and Krämer, A. and Reichle, A. and Gnadler, M. and Willekens, C. and Spiekermann, K. and Hiddemann, W. and Müller-Tidow, C. and Thiede, C. and Röllig, C. and Serve, H. and Bornhäuser, M. and Baldus, C.D. and Lengfelder, E. and Fenaux, P. and Platzbecker, U. and Adès, L.
Haematologica 106 (12): 3100-3106. December 2021

Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow, J. and Gross, S. and Busack, L. and Flörcken, A. and Jesse, J. and Schwarz, M. and Neuendorff, N.R. and von Brünneck, A.C. and Anagnostopoulos, I. and Türkmen, S. and Blau, I.W. and Burmeister, T. and Horst, D. and Bullinger, L. and Westermann, J.
Haematologica 11 November 2021 (In Press)


A CD205-directed antibody drug conjugate - lymphoma precision oncology or sophisticated chemotherapy?
Rieke, D.T. and Keller, U.
Haematologica 105 (11): 2504-2506. 1 November 2020

Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.
Tausch, E. and Beck, P. and Schlenk, R.F. and Jebaraj, B.M.C. and Dolnik, A. and Yosifov, D.Y. and Hillmen, P. and Offner, F. and Janssens, A. and Babu, K.G. and Grosicki, S. and Mayer, J. and Panagiotidis, P. and McKeown, A. and Gupta, I.V. and Skorupa, A. and Pallaud, C. and Bullinger, L. and Mertens, D. and Döhner, H. and Stilgenbauer, S.
Haematologica 105 (10): 2440-2447. October 2020

Endothelial damage and dysfunction in acute graft-versus-host disease.
Cordes, S. and Mokhtari, Z. and Bartosova, M. and Mertlitz, S. and Riesner, K. and Shi, Y. and Mengwasser, J. and Kalupa, M. and McGeary, A. and Schleifenbaum, J. and Schrezenmeier, J. and Bullinger, L. and Diaz-Ricart, M. and Palomo, M. and Carrreras, E. and Beutel, G. and Schmitt, C.P. and Beilhack, A. and Penack, O.
Haematologica 106 (8): 2147-2160. 1 August 2020

Clonal hematopoiesis in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis.
Arends, C.M. and Weiss, M. and Christen, F. and Eulenberg-Gustavus, C. and Rousselle, A. and Kettritz, R. and Eckardt, K.U. and Chan, W. and Hoyer, K. and Frick, M. and Bullinger, L. and Bieringer, M. and Schreiber, A. and Damm, F.
Haematologica 105 (6): e264-e267. June 2020

Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.
Jiang, S. and Penack, O. and Terzer, T. and Schult, D. and Majer-Lauterbach, J. and Radujkovic, A. and Blau, I.W. and Bullinger, L. and Müller-Tidow, C. and Dreger, P. and Luft, T.
Haematologica 106 (2): 446-453. February 2020


IFNα-mediated remodeling of endothelial cells in the bone marrow niche.
Prendergast, Á.M. and Kuck, A. and van Essen, M. and Haas, S. and Blaszkiewicz, S. and Essers, M.A.G.
Haematologica 102 (3): 445-453. March 2017


Organ siderosis and hemophagocytosis during acute graft-versus-host disease.
Nogai, A. and Shi, Y. and Perez-Hernandez, D. and Cordes, S. and Mengwasser, J. and Mertlitz, S. and Riesner, K. and Kalupa, M. and Erdmann, J.H. and Ziebig, R. and Dittmar, G. and Penack, O.
Haematologica 101 (8): e344-e346. August 2016

The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A. and Balduini, C. and Brand, A. and Coiffier, B. and Cordonnier, C. and Doehner, H. and Duyvene' de Wit, T. and Eichinger, S. and Fibbe, W. and Green, T. and de Haas, F. and Iolascon, A. and Jaffredo, T. and Rodeghiero, F. and Salles, G. and Schuringa, J.J.
Haematologica 101 (2): 115-208. February 2016


Rabbit antithymocyte globulin (Thymoglobulin(R)) impairs the thymic output of both conventional and regulatory CD4(+) T cells after allogeneic hematopoietic stem cell transplantation in adult patients.
Na, I.K. and Wittenbecher, F. and Dziubianau, M. and Herholz, A. and Mensen, A. and Kunkel, D. and Blau, O. and Blau, I. and Thiel, E. and Uharek, L. and Scheibenbogen, C. and Rieger, K. and Thiel, A.
Haematologica 98 (1): 23-30. January 2013


Clinical cardiac safety profile of nilotinib.
Kim, T.D. and le Coutre, P. and Schwarz, M. and Grille, P. and Levitin, M. and Fateh-Moghadam, S. and Giles, F.J. and Doerken, B. and Haverkamp, W. and Koehncke, C.
Haematologica 97 (6): 883-889. June 2012


Eukaryotic initiation factor 2α phosphorylation is required for B cell maturation and function in mice.
Mielke, N. and Schwarzer, R. and Calkhoven, C.F. and Kaufman, R. and Doerken, B. and Leutz, A. and Jundt, F.
Haematologica 96 (9): 1261-1268. September 2011


Common clonal origin of an acute B lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity.
Ratei, R. and Hummel, M. and Anagnostopoulos, I. and Jaehne, D. and Arnold, R. and Doerken, B. and Mathas, S. and Thomas, B. and Dudeck, O. and Ludwig, W.D. and Stein, H.
Haematologica 95 (9): 1461-1466. September 2010

A modified EBMT risk score and the hematopoietic cell transplantation-specific comorbidity index for pre-transplant risk assessment in adult acute lymphoblastic leukemia.
Terwey, T.H. and Hemmati, P.G. and Martus, P. and Dietz, E. and Vuong, L.G. and Massenkeil, G. and Doerken, B. and Arnold, R.
Haematologica 95 (5): 810-818. May 2010

Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D. and Tuerkmen, S. and Schwarz, M. and Koca, G. and Nogai, H. and Bommer, C. and Doerken, B. and Daniel, P. and le Coutre, P.
Haematologica 95 (4): 582-588. April 2010


Angiotensin-(1-7) stimulates hematopoietic progenitor cells in vitro and in vivo.
Heringer-Walther, S. and Eckert, K. and Schumacher, S.M. and Uharek, L. and Wulf-Goldenberg, A. and Gembardt, F. and Fichtner, I. and Schultheiss, H.P. and Rodgers, K. and Walther, T.
Haematologica 94 (6): 857-860. June 2009


Anthropometric characteristics and non-Hodgkin's lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Britton, J.A. and Khan, A.E. and Rohrmann, S. and Becker, N. and Linseisen, J. and Nieters, A. and Kaaks, R. and Tjonneland, A. and Halkjaer, J. and Severinsen, M.T. and Overvad, K. and Pischon, T. and Boeing, H. and Trichopoulou, A. and Kalapothaki, V. and Trichopoulos, D. and Mattiello, A. and Tagliabue, G. and Sacerdote, C. and Peeters, P.H. and Bueno-de-Mesquita, H.B. and Ardanaz, E. and Navarro, C. and Jakszyn, P. and Altzibar, J.M. and Hallmans, G. and Malmer, B. and Berglund, G. and Manjer, J. and Allen, N. and Key, T. and Bingham, S. and Besson, H. and Ferrari, P. and Jenab, M. and Boffetta, P. and Vineis, P. and Riboli, E.
Haematologica 93 (11): 1666-1677. November 2008

The pathogenesis of classical Hodgkin's lymphoma: what can we learn from analyses of genomic alterations in Hodgkin and Reed-Sternberg cells?
Janz, M. and Mathas, S.
Haematologica 93 (9): 1292-1295. September 2008


Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.
Wuchter, C. and Richter, S. and Oltersdorf, D. and Karawajew, L. and Ludwig, W.D. and Tamm, I.
Haematologica 89 : 363-364. 1 March 2004


Detection of minimal residual disease in unselected patients with acute myeloid leukemia using multiparameter flow cytometry for definition of leukemia-associated immunophenotypes and determination of their frequencies in normal bone marrow.
Kern, W. and Danhauser-Riedl, S. and Ratei, R. and Schnittger, S. and Schoch, C. and Kolb, H.J. and Ludwig, W.D. and Hiddemann, W. and Haferlach, T.
Haematologica 88 : 646-653. 1 June 2003


Quantification of human cells in NOD/SCID mice by duplex real-time polymerase reaction.
Nitsche, A. and Becker, M. and Junghahn, I. and Aumann, J. and Landt, O. and Fichtner, I. and Wittig, B. and Siegert, W.
Haematologica 86 : 693-699. 1 January 2001

Impact of CD133 (AC133) and CD90 expression analysis for acute leukemia immunophenotyping.
Wuchter, C. and Ratei, R. and Spahn, G. and Schoch, C. and Harbott, J. and Schnittger, S. and Haferlach, T. and Creutzig, U. and Sperling, C. and Karawajew, L. and Ludwig, W.D.
Haematologica 86 : 154-161. 1 January 2001


Clinical significance of P-glycoprotein expression and function for response to induction chemotherapy, relapse rate and overall survival in acute leukemia.
Wuchter, C. and Karawajew, L. and Ruppert, V. and Schrappe, M. and Buechner, T. and Schoch, C. and Haferlach, T. and Harbott, J.N. and Ratei, R. and Doerken, B. and Ludwig, W.D.
Haematologica 85 : 711-721. 1 July 2000


Impact of immunophenotyping on management of acute leukemias.
Bene, M.C. and Bernier, M. and Castoldi, G. and Faure, G.C. and Knapp, W. and Ludwig, W.D. and Matutes, E. and Orfao, A. and van't Veer, M.
Haematologica 84 : 1024-1034. 1 November 1999


Expression of the stem cell factor receptor c-kit (CD117) in acute leukemias.
Sperling, C. and Schwartz, S. and Buechner, T. and Thiel, E. and Ludwig, W.D.
Haematologica 82 : 617-621. 1 January 1997

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