Browse by Journal Title

2024

HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation.
Welters, C. and Welters, M.L. and Stadler, S. and Bullinger, L. and Strobel, J. and Hackstein, H. and Dhamodaran, A. and Blankenstein, T. and Hansmann, L.
Haematologica 109 (4): 1121-1127. April 2024

Update and European consensus on a patient-centered core outcome set for multiple myeloma in clinical practice and research.
Oerlemans, S. and De Rooij, B.H. and Bennink, C. and Bullinger, L. and Broijl, A. and D'Agostino, M. and Laane, E. and Lupo-Stanghellini, M.T. and Perrot, A. and Wester, R. and Cursaru, V. and Scheurer, H. and Vesseur, J. and Dalal, M. and Sen, R. and Stamm, T. and Ludwig, H. and Sonneveld, P.
Haematologica 1 February 2024 (In Press)

Frequent, high density expression of surface CD38 as a potential therapeutic target in adult T-lineage acute lymphoblastic leukemia.
Koslowski, S. and Glauben, R. and Habringer, S. and Burmeister, T. and Keller, U. and Brüggemann, M. and Gökbuget, N. and Schwartz, S.
Haematologica 109 (2): 661-665. February 2024

2023

Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia.
Kayser, S. and Martínez-Cuadrón, D. and Rodriguez-Veiga, R. and Hänel, M. and Tormo, M. and Schäfer-Eckart, K. and Botella, C. and Stölzel, F. and Del Castillo, T.B. and Keller, U. and Rodriguez-Medina, C. and Held, G. and Amigo, M.L. and Schliemann, C. and Colorado, M. and Kaufmann, M. and Garcia, M.B. and Krause, S.W. and Görner, M. and Jost, E. and Steffen, B. and Zukunft, S. and Platzbecker, U. and Ho, A.D. and Baldus, C.D. and Serve, H. and Müller-Tidow, C. and Thiede, C. and Bornhäuser, M. and Montesinos, P. and Röllig, C. and Schlenk, R.F.
Haematologica 108 (8): 2059-2066. August 2023

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas.
Lopez, C. and Schleussner, N. and Bernhart, S.H. and Kleinheinz, K. and Sungalee, S. and Sczakiel, H.L. and Kretzmer, H. and Toprak, U.H. and Glaser, S. and Wagener, R. and Ammerpohl, O. and Bens, S. and Giefing, M. and Sanchez, J.C.G. and Apic, G. and Hubschmann, D. and Janz, M. and Kreuz, M. and Mottok, A. and Müller, J.M. and Seufert, J. and Hoffmann, S. and Korbel, J.O. and Russell, R.B. and Schule, R. and Trumper, L. and Klapper, W. and Radlwimmer, B. and Lichter, P. and Kuppers, R. and Schlesner, M. and Mathas, S. and Siebert, R.
Haematologica 108 (2): 543-554. 1 February 2023

Small molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy.
Demel, U.M. and Wirth, M. and Yousefian, S. and Zhang, L. and Isaakidis, K. and Dönig, J. and Böger, M. and Singh, N. and Köse, H. and Haas, S. and Müller, S. and Schick, M. and Keller, U.
Haematologica 108 (2): 555-567. February 2023

Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B cell impairment and increases the risk for infections - a retrospective matched cohort study.
Launspach, M. and Temel, D. and Ohlendorf, E. and Zirngibl, F. and Materne, B. and Oevermann, L. and Deubzer, H.E. and Henssen, A.G. and Künkele, A. and Hundsdörfer, P. and von Bernuth, H. and Pruß, A. and Eggert, A. and von Stackelberg, A. and Lang, P. and Schulte, J.H.
Haematologica 108 (1): 267-272. January 2023

2022

The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S. and Cabantog, A. and MacPhee, L. and Im, J. and Ruess, C. and Demir, B. and Sperb, N. and Rücker, F.G. and Döhner, K. and Herold, T. and Pollack, J.R. and Bullinger, L. and Rouhi, A. and Kuchenbauer, F.
Haematologica 107 (8): 1758-1772. August 2022

Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow, J. and Gross, S. and Busack, L. and Flörcken, A. and Jesse, J. and Schwarz, M. and Neuendorff, N.R. and von Brünneck, A.C. and Anagnostopoulos, I. and Türkmen, S. and Blau, I.W. and Burmeister, T. and Horst, D. and Bullinger, L. and Westermann, J.
Haematologica 107 (8): 1773-1785. August 2022

B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
Schmid, V.K. and Khadour, A. and Ahmed, N. and Brandl, C. and Nitschke, L. and Rajewsky, K. and Jumaa, H. and Hobeika, E.
Haematologica 107 (8): 1796-1814. August 2022

Clonal hematopoiesis of indeterminate potential-related epigenetic age acceleration correlates with clonal hematopoiesis of indeterminate potential clone size in patients with high morbidity.
Feldkamp, J.D. and Vetter, V.M. and Arends, C.M. and Lang, T.J.L. and Bullinger, L. and Damm, F. and Demuth, I. and Frick, M.
Haematologica 107 (7): 1703-1708. July 2022

Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways.
Braun, T. and Glass, M. and Wahnschaffe, L. and Otte, M. and Mayer, P. and Franitza, M. and Altmüller, J. and Hallek, M. and Hüttelmaier, S. and Schrader, A. and Herling, M.
Haematologica 107 (1): 187-200. January 2022

2021

Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide - an international collaborative study.
Kayser, S. and Schlenk, R.F. and Lebon, D. and Carre, M. and Götze, K.S. and Stölzel, F. and Berceanu, A. and Schäfer-Eckart, K. and Peterlin, P. and Hicheri, Y. and Rahme, R. and Raffoux, E. and Chermat, F. and Krause, S.W. and Aulitzky, W.E. and Rigaudeau, S. and Noppeney, R. and Berthon, C. and Görner, M. and Jost, E. and Carassou, P. and Keller, U. and Orvain, C. and Braun, T. and Saillard, C. and Arar, A. and Kunzmann, V. and Wemeau, M. and De Wit, M. and Niemann, D. and Bonmati, C. and Schwänen, C. and Abraham, J. and Aljijakli, A. and Haiat, S. and Krämer, A. and Reichle, A. and Gnadler, M. and Willekens, C. and Spiekermann, K. and Hiddemann, W. and Müller-Tidow, C. and Thiede, C. and Röllig, C. and Serve, H. and Bornhäuser, M. and Baldus, C.D. and Lengfelder, E. and Fenaux, P. and Platzbecker, U. and Adès, L.
Haematologica 106 (12): 3100-3106. December 2021

2020

A CD205-directed antibody drug conjugate - lymphoma precision oncology or sophisticated chemotherapy?
Rieke, D.T. and Keller, U.
Haematologica 105 (11): 2504-2506. 1 November 2020

Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.
Tausch, E. and Beck, P. and Schlenk, R.F. and Jebaraj, B.M.C. and Dolnik, A. and Yosifov, D.Y. and Hillmen, P. and Offner, F. and Janssens, A. and Babu, K.G. and Grosicki, S. and Mayer, J. and Panagiotidis, P. and McKeown, A. and Gupta, I.V. and Skorupa, A. and Pallaud, C. and Bullinger, L. and Mertens, D. and Döhner, H. and Stilgenbauer, S.
Haematologica 105 (10): 2440-2447. October 2020

Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia.
In't Hout, F.E.M. and Gerritsen, M. and Bullinger, L. and Van der Reijden, B.A. and Huls, G. and Vellenga, E. and Jansen, J.H.
Haematologica 105 (9): e454-457. 1 September 2020

The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Grasedieck, S. and Ruess, C. and Krowiorz, K. and Lux, S. and Pochert, N. and Schwarzer, A. and Klusmann, J.H. and Jongen-Lavrencic, M. and Herold, T. and Bullinger, L. and Pollack, J.R. and Rouhi, A. and Kuchenbauer, F.
Haematologica 105 (9): e448-e453. September 2020

Endothelial damage and dysfunction in acute graft-versus-host disease.
Cordes, S. and Mokhtari, Z. and Bartosova, M. and Mertlitz, S. and Riesner, K. and Shi, Y. and Mengwasser, J. and Kalupa, M. and McGeary, A. and Schleifenbaum, J. and Schrezenmeier, J. and Bullinger, L. and Diaz-Ricart, M. and Palomo, M. and Carrreras, E. and Beutel, G. and Schmitt, C.P. and Beilhack, A. and Penack, O.
Haematologica 106 (8): 2147-2160. 1 August 2020

Clonal hematopoiesis in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis.
Arends, C.M. and Weiss, M. and Christen, F. and Eulenberg-Gustavus, C. and Rousselle, A. and Kettritz, R. and Eckardt, K.U. and Chan, W. and Hoyer, K. and Frick, M. and Bullinger, L. and Bieringer, M. and Schreiber, A. and Damm, F.
Haematologica 105 (6): e264-e267. June 2020

Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Edelmann, J. and Holzmann, K. and Tausch, E. and Saunderson, E.A. and Jebaraj, B.M.C. and Steinbrecher, D. and Dolnik, A. and Blätte, T.J. and Landau, D.A. and Saub, J. and Estenfelder, S. and Ibach, S. and Cymbalista, F. and Leblond, V. and Delmer, A. and Bahlo, J. and Robrecht, S. and Fischer, K. and Goede, V. and Bullinger, L. and Wu, C.J. and Mertens, D. and Ficz, G. and Gribben, J.G. and Hallek, M. and Döhner, H. and Stilgenbauer, S.
Haematologica 105 (5): 1379-1390. May 2020

Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.
Jiang, S. and Penack, O. and Terzer, T. and Schult, D. and Majer-Lauterbach, J. and Radujkovic, A. and Blau, I.W. and Bullinger, L. and Müller-Tidow, C. and Dreger, P. and Luft, T.
Haematologica 106 (2): 446-453. February 2020

2019

Venetoclax resistance and acquired mutations in chronic lymphocytic leukemia.
Tausch, E. and Close, W. and Dolnik, A. and Bloehdorn, J. and Chyla, B. and Bullinger, L. and Döhner, H. and Mertens, D. and Stilgenbauer, S.
Haematologica 104 (9): e434-e437. September 2019

2018

Micro-ribonucleic acid-155 is a direct target of Meis1, but not a driver in acute myeloid leukemia.
Schneider, E. and Staffas, A. and Röhner, L. and Malmberg, E.D. and Ashouri, A. and Krowiorz, K. and Pochert, N. and Miller, C. and Wei, S.Y. and Arabanian, L. and Buske, C. and Döhner, H. and Bullinger, L. and Fogelstrand, L. and Heuser, M. and Döhner, K. and Xiang, P. and Ruschmann, J. and Petriv, O.I. and Heravi-Moussavi, A. and Hansen, C.L. and Hirst, M. and Humphries, R.K. and Rouhi, A. and Palmqvist, L. and Kuchenbauer, F.
Haematologica 103 (2): 246-255. February 2018

Chromothripsis is linked to alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype.
Rücker, F.G. and Dolnik, A. and Blätte, T.J. and Teleanu, V. and Ernst, A. and Thol, F. and Heuser, M. and Ganser, A. and Döhner, H. and Döhner, K. and Bullinger, L.
Haematologica 103 (1): e17-e20. January 2018

2017

Acute myeloid leukemia with mutated nucleophosmin 1: an immunogenic acute myeloid leukemia subtype and potential candidate for immune checkpoint inhibition.
Greiner, J. and Hofmann, S. and Schmitt, M. and Götz, M. and Wiesneth, M. and Schrezenmeier, H. and Bunjes, D. and Döhner, H. and Bullinger, L.
Haematologica 102 (12): e499-e501. December 2017

Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia.
Hirsch, S. and Blätte, T.J. and Grasedieck, S. and Cocciardi, S. and Rouhi, A. and Jongen-Lavrencic, M. and Paschka, P. and Krönke, J. and Gaidzik, V.I. and Döhner, H. and Schlenk, R.F. and Kuchenbauer, F. and Döhner, K. and Dolnik, A. and Bullinger, L.
Haematologica 102 (12): 2039-2047. December 2017

IFNα-mediated remodeling of endothelial cells in the bone marrow niche.
Prendergast, Á.M. and Kuck, A. and van Essen, M. and Haas, S. and Blaszkiewicz, S. and Essers, M.A.G.
Haematologica 102 (3): 445-453. March 2017

2016

MicroRNA expression-based outcome prediction in acute myeloid leukemia: novel insights through cross-platform integrative analyses.
Shivarov, V. and Dolnik, A. and Lang, K.M. and Krönke, J. and Kuchenbauer, F. and Paschka, P. and Gaidzik, V.I. and Döhner, H. and Schlenk, R.F. and Döhner, K. and Bullinger, L.
Haematologica 101 (11): e454-e456. November 2016

Organ siderosis and hemophagocytosis during acute graft-versus-host disease.
Nogai, A. and Shi, Y. and Perez-Hernandez, D. and Cordes, S. and Mengwasser, J. and Mertlitz, S. and Riesner, K. and Kalupa, M. and Erdmann, J.H. and Ziebig, R. and Dittmar, G. and Penack, O.
Haematologica 101 (8): e344-e346. August 2016

The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A. and Balduini, C. and Brand, A. and Coiffier, B. and Cordonnier, C. and Doehner, H. and Duyvene' de Wit, T. and Eichinger, S. and Fibbe, W. and Green, T. and de Haas, F. and Iolascon, A. and Jaffredo, T. and Rodeghiero, F. and Salles, G. and Schuringa, J.J.
Haematologica 101 (2): 115-208. February 2016

2015

ASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study Group.
Paschka, P. and Schlenk, R.F. and Gaidzik, V.I. and Herzig, J.K. and Aulitzky, T. and Bullinger, L. and Späth, D. and Teleanu, V. and Kündgen, A. and Köhne, C.H. and Brossart, P. and Held, G. and Horst, H.A. and Ringhoffer, M. and Götze, K. and Nachbaur, D. and Kindler, T. and Heuser, M. and Thol, F. and Ganser, A. and Döhner, H. and Döhner, K.
Haematologica 100 (3): 324-330. March 2015

2013

HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy.
Dickson, G.J. and Liberante, F.G. and Kettyle, L.M. and O'Hagan, K.A. and Finnegan, D.P.J. and Bullinger, L. and Geerts, D. and McMullin, M.F. and Lappin, T.R.J. and Mills, K.I. and Thompson, A.
Haematologica 98 (8): 1216-25. August 2013

Rabbit antithymocyte globulin (Thymoglobulin(R)) impairs the thymic output of both conventional and regulatory CD4(+) T cells after allogeneic hematopoietic stem cell transplantation in adult patients.
Na, I.K. and Wittenbecher, F. and Dziubianau, M. and Herholz, A. and Mensen, A. and Kunkel, D. and Blau, O. and Blau, I. and Thiel, E. and Uharek, L. and Scheibenbogen, C. and Rieger, K. and Thiel, A.
Haematologica 98 (1): 23-30. January 2013

2012

Clinical cardiac safety profile of nilotinib.
Kim, T.D. and le Coutre, P. and Schwarz, M. and Grille, P. and Levitin, M. and Fateh-Moghadam, S. and Giles, F.J. and Doerken, B. and Haverkamp, W. and Koehncke, C.
Haematologica 97 (6): 883-889. June 2012

2011

Eukaryotic initiation factor 2α phosphorylation is required for B cell maturation and function in mice.
Mielke, N. and Schwarzer, R. and Calkhoven, C.F. and Kaufman, R. and Doerken, B. and Leutz, A. and Jundt, F.
Haematologica 96 (9): 1261-1268. September 2011

2010

Common clonal origin of an acute B lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity.
Ratei, R. and Hummel, M. and Anagnostopoulos, I. and Jaehne, D. and Arnold, R. and Doerken, B. and Mathas, S. and Thomas, B. and Dudeck, O. and Ludwig, W.D. and Stein, H.
Haematologica 95 (9): 1461-1466. September 2010

A modified EBMT risk score and the hematopoietic cell transplantation-specific comorbidity index for pre-transplant risk assessment in adult acute lymphoblastic leukemia.
Terwey, T.H. and Hemmati, P.G. and Martus, P. and Dietz, E. and Vuong, L.G. and Massenkeil, G. and Doerken, B. and Arnold, R.
Haematologica 95 (5): 810-818. May 2010

Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D. and Tuerkmen, S. and Schwarz, M. and Koca, G. and Nogai, H. and Bommer, C. and Doerken, B. and Daniel, P. and le Coutre, P.
Haematologica 95 (4): 582-588. April 2010

2009

Angiotensin-(1-7) stimulates hematopoietic progenitor cells in vitro and in vivo.
Heringer-Walther, S. and Eckert, K. and Schumacher, S.M. and Uharek, L. and Wulf-Goldenberg, A. and Gembardt, F. and Fichtner, I. and Schultheiss, H.P. and Rodgers, K. and Walther, T.
Haematologica 94 (6): 857-860. June 2009

2008

Anthropometric characteristics and non-Hodgkin's lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Britton, J.A. and Khan, A.E. and Rohrmann, S. and Becker, N. and Linseisen, J. and Nieters, A. and Kaaks, R. and Tjonneland, A. and Halkjaer, J. and Severinsen, M.T. and Overvad, K. and Pischon, T. and Boeing, H. and Trichopoulou, A. and Kalapothaki, V. and Trichopoulos, D. and Mattiello, A. and Tagliabue, G. and Sacerdote, C. and Peeters, P.H. and Bueno-de-Mesquita, H.B. and Ardanaz, E. and Navarro, C. and Jakszyn, P. and Altzibar, J.M. and Hallmans, G. and Malmer, B. and Berglund, G. and Manjer, J. and Allen, N. and Key, T. and Bingham, S. and Besson, H. and Ferrari, P. and Jenab, M. and Boffetta, P. and Vineis, P. and Riboli, E.
Haematologica 93 (11): 1666-1677. November 2008

The pathogenesis of classical Hodgkin's lymphoma: what can we learn from analyses of genomic alterations in Hodgkin and Reed-Sternberg cells?
Janz, M. and Mathas, S.
Haematologica 93 (9): 1292-1295. September 2008

2004

Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.
Wuchter, C. and Richter, S. and Oltersdorf, D. and Karawajew, L. and Ludwig, W.D. and Tamm, I.
Haematologica 89 : 363-364. 1 March 2004

2003

Detection of minimal residual disease in unselected patients with acute myeloid leukemia using multiparameter flow cytometry for definition of leukemia-associated immunophenotypes and determination of their frequencies in normal bone marrow.
Kern, W. and Danhauser-Riedl, S. and Ratei, R. and Schnittger, S. and Schoch, C. and Kolb, H.J. and Ludwig, W.D. and Hiddemann, W. and Haferlach, T.
Haematologica 88 : 646-653. 1 June 2003

2001

Quantification of human cells in NOD/SCID mice by duplex real-time polymerase reaction.
Nitsche, A. and Becker, M. and Junghahn, I. and Aumann, J. and Landt, O. and Fichtner, I. and Wittig, B. and Siegert, W.
Haematologica 86 : 693-699. 1 January 2001

Impact of CD133 (AC133) and CD90 expression analysis for acute leukemia immunophenotyping.
Wuchter, C. and Ratei, R. and Spahn, G. and Schoch, C. and Harbott, J. and Schnittger, S. and Haferlach, T. and Creutzig, U. and Sperling, C. and Karawajew, L. and Ludwig, W.D.
Haematologica 86 : 154-161. 1 January 2001

2000

Clinical significance of P-glycoprotein expression and function for response to induction chemotherapy, relapse rate and overall survival in acute leukemia.
Wuchter, C. and Karawajew, L. and Ruppert, V. and Schrappe, M. and Buechner, T. and Schoch, C. and Haferlach, T. and Harbott, J.N. and Ratei, R. and Doerken, B. and Ludwig, W.D.
Haematologica 85 : 711-721. 1 July 2000

1999

Impact of immunophenotyping on management of acute leukemias.
Bene, M.C. and Bernier, M. and Castoldi, G. and Faure, G.C. and Knapp, W. and Ludwig, W.D. and Matutes, E. and Orfao, A. and van't Veer, M.
Haematologica 84 : 1024-1034. 1 November 1999

1997

Expression of the stem cell factor receptor c-kit (CD117) in acute leukemias.
Sperling, C. and Schwartz, S. and Buechner, T. and Thiel, E. and Ludwig, W.D.
Haematologica 82 : 617-621. 1 January 1997