Article

Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD.
Gonzalez-Acera, Miguel, Patankar, Jay V. ORCID: https://orcid.org/0000-0002-1884-7424, Erkert, Lena, Cineus, Roodline, Gamez-Belmonte, Reyes, Leupold, Tamara, Bubeck, Marvin, Bao, Li-Li, Dinkel, Martin, Wang, Ru, Schickedanz, Laura, Limberger, Heidi, Stolzer, Iris, Gerlach, Katharina, Diemand, Leonard, Mascia, Fabrizio, Gupta, Pooja, Naschberger, Elisabeth ORCID: https://orcid.org/0000-0003-1291-622X, Koop, Kristina ORCID: https://orcid.org/0000-0002-1672-7234, Plattner, Christina, Sturm, Gregor, Weigmann, Benno ORCID: https://orcid.org/0000-0002-2398-0844, Günther, Claudia ORCID: https://orcid.org/0000-0001-8360-3525, Wirtz, Stefan, Stürzl, Michael ORCID: https://orcid.org/0000-0002-9276-2824, Hildner, Kai, Kühl, Anja A., Siegmund, Britta ORCID: https://orcid.org/0000-0002-0055-958X, Gießl, Andreas, Atreya, Raja ORCID: https://orcid.org/0000-0002-8556-8433, Hegazy, Ahmed N., Trajanoski, Zlatko, Neurath, Markus F. ORCID: https://orcid.org/0000-0003-4344-1474 and Becker, Christoph ORCID: https://orcid.org/0000-0002-1388-1041
Gut 74 (10): 1602-1615. 8 September 2025

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
Belda, E., Voland, L., Tremaroli, V., Falony, G. ORCID: https://orcid.org/0000-0003-2450-0782, Adriouch, S., Assmann, K.E., Prifiti, E., Aron-Wisnewsky, J., Debédat, J. ORCID: https://orcid.org/0000-0002-8377-5965, Le Roy, T. ORCID: https://orcid.org/0000-0002-0874-1490, Nielsen, T. ORCID: https://orcid.org/0000-0002-2066-7895, Amouyal, C., André, S., Andreelli, F., Blüher, M., Chakaroun, R. ORCID: https://orcid.org/0000-0001-9901-1815, Chilloux, J., Coelho, L.P., Dao, M.C., Das, P., Fellahi, S., Forslund, S. ORCID: https://orcid.org/0000-0003-4285-6993, Galleron, N., Hansen, T.H. ORCID: https://orcid.org/0000-0001-8748-3831, Holmes, B., Ji, B., Krogh Pedersen, H., Le, P., Le Chatelier, E., Lewinter, C., Mannerås-Holm, L., Marquet, F., Myridakis, A., Pelloux, V., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J.E., Sokolovska, N., Søndertoft, N.B., Touch, S., Vieira-Silva, S., Galan, P., Holst, J., Gøtze, J.P., Køber, L., Vestergaard, H., Hansen, T., Hercberg, S., Oppert, J.M., Nielsen, J., Letunic, I., Dumas, M.E. ORCID: https://orcid.org/0000-0001-9523-7024, Stumvoll, M., Pedersen, O.B., Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X, Ehrlich, S.D., Zucker, J.D., Bäckhed, F. ORCID: https://orcid.org/0000-0002-4871-8818, Raes, J. and Clément, K. ORCID: https://orcid.org/0000-0002-2489-3355
Gut 71 (12): 2463-2480. 7 November 2022

A faecal microbiota signature with high specificity for pancreatic cancer.
Kartal, E. ORCID: https://orcid.org/0000-0002-7720-455X, Schmidt, T.S.B. ORCID: https://orcid.org/0000-0001-8587-4177, Molina-Montes, E. ORCID: https://orcid.org/0000-0002-0428-2426, Rodríguez-Perales, S. ORCID: https://orcid.org/0000-0001-7221-3636, Wirbel, J. ORCID: https://orcid.org/0000-0002-4073-3562, Maistrenko, O.M. ORCID: https://orcid.org/0000-0003-1961-7548, Akanni, W.A. ORCID: https://orcid.org/0000-0002-2075-2387, Alashkar Alhamwe, B. ORCID: https://orcid.org/0000-0002-7120-0013, Alves, R.J. ORCID: https://orcid.org/0000-0002-7212-0234, Carrato, A. ORCID: https://orcid.org/0000-0001-7749-8140, Erasmus, H.P., Estudillo, L. ORCID: https://orcid.org/0000-0003-3891-3713, Finkelmeier, F., Fullam, A. ORCID: https://orcid.org/0000-0002-0884-8124, Glazek, A.M., Gómez-Rubio, P., Hercog, R., Jung, F. ORCID: https://orcid.org/0000-0002-5534-7832, Kandels, S. ORCID: https://orcid.org/0000-0002-4194-4927, Kersting, S. ORCID: https://orcid.org/0000-0002-2124-3103, Langheinrich, M. ORCID: https://orcid.org/0000-0002-0120-9135, Márquez, M., Molero, X., Orakov, A. ORCID: https://orcid.org/0000-0001-6823-5269, Van Rossum, T. ORCID: https://orcid.org/0000-0002-3598-5001, Torres-Ruiz, R. ORCID: https://orcid.org/0000-0001-9606-0398, Telzerow, A. ORCID: https://orcid.org/0000-0001-9855-0809, Zych, K. ORCID: https://orcid.org/0000-0001-7426-0516, Benes, V. ORCID: https://orcid.org/0000-0002-0352-2547, Zeller, G. ORCID: https://orcid.org/0000-0003-1429-7485, Trebicka, J. ORCID: https://orcid.org/0000-0002-7028-3881, Real, F.X. ORCID: https://orcid.org/0000-0001-9501-498X, Malats, N. ORCID: https://orcid.org/0000-0003-2538-3784 and Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X
Gut 71 (7): 1359-1372. 7 June 2022

Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women.
Hur, J. ORCID: https://orcid.org/0000-0003-0968-208X, Otegbeye, E. ORCID: https://orcid.org/0000-0001-5403-3615, Joh, H.K., Nimptsch, K. ORCID: https://orcid.org/0000-0001-7877-205X, Ng, K., Ogino, S. ORCID: https://orcid.org/0000-0002-3909-2323, Meyerhardt, J.A., Chan, A.T., Willett, W.C., Wu, K., Giovannucci, E. ORCID: https://orcid.org/0000-0002-6123-0219 and Cao, Y. ORCID: https://orcid.org/0000-0001-9835-7662
Gut 70 (12): 2330-2336. December 2021

Human and preclinical studies of the host-gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health.
Brial, F., Chilloux, J., Nielsen, T., Vieira-Silva, S., Falony, G., Andrikopoulos, P., Olanipekun, M., Hoyles, L., Djouadi, F., Neves, A.L., Rodriguez-Martinez, A., Mouawad, G.I., Pons, N., Forslund, S. ORCID: https://orcid.org/0000-0003-4285-6993, Le-Chatelier, E., Le Lay, A., Nicholson, J., Hansen, T., Hyötyläinen, T., Clément, K., Oresic, M., Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X, Ehrlich, S.D., Raes, J., Pedersen, O.B., Gauguier, D. and Dumas, M.E. ORCID: https://orcid.org/0000-0001-9523-7024
Gut 70 (11): 2105-2114. 7 October 2021

SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
Biederstädt, A., Hassan, Z., Schneeweis, C., Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Schneider, L., Muckenhuber, A., Hong, Y., Siegers, G., Nilsson, L., Wirth, M., Dantes, Z., Steiger, K., Schunck, K., Langston, S., Lenhof, H.P., Coluccio, A., Orben, F., Slawska, J., Scherger, A., Saur, D., Müller, S., Rad, R., Weichert, W., Nilsson, J., Reichert, M. ORCID: https://orcid.org/0000-0002-8611-5639, Schneider, G. ORCID: https://orcid.org/0000-0003-1840-4508 and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Gut 69 (8): 1472-1482. August 2020

Antibiotics-induced monodominance of a novel gut bacterial order.
Hildebrand, F. ORCID: https://orcid.org/0000-0002-0078-8948, Moitinho-Silva, L., Blasche, S., Jahn, M.T.T. ORCID: https://orcid.org/0000-0001-8322-9334, Gossmann, T.I., Heuerta Cepas, J., Hercog, R., Luetge, M., Bahram, M., Pryszlak, A., Alves, R.J., Waszak, S.M., Zhu, A., Ye, L., Costea, P.I., Aalvink, S., Belzer, C., Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Sunagawa, S., Hentschel, U., Merten, C., Patil, K.R., Benes, V. and Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X
Gut 68 (10): 1781-1790. 9 September 2019

Population-level analysis of Blastocystis subtype prevalence and variation in the human gut microbiota.
Tito, R.Y., Chaffron, S., Caenepeel, C., Lima-Mendez, G., Wang, J., Vieira-Silva, S., Falony, G., Hildebrand, F., Darzi, Y., Rymenans, L., Verspecht, C., Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X, Vermeire, S., Joossens, M. and Raes, J.
Gut 68 (7): 1180-1189. 7 June 2019

Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma.
Lee, A.Y.L., Dubois, C.L., Sarai, K., Zarei, S., Schaeffer, D.F., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Kopp, J. L.
Gut 68 (3): 487-498. March 2019

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Qi, J., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Akilli Öztürk, Ö., Holland, J.D., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Fritzmann, J., Wulf-Goldenberg, A., Eckert, K., Fichtner, I. and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Gut 65 (10): 1690-1701. October 2016

Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α.
Brooke, M.A., Longhurst, H.J., Plagnol, V., Kirkby, N.S., Mitchell, J.A., Rüschendorf, F. ORCID: https://orcid.org/0000-0001-5640-810X, Warner, T.D., Kelsell, D.P. and MacDonald, T.T.
Gut 63 (1): 96-104. January 2014

Blood lipid and lipoprotein concentrations and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition.
van Duijnhoven, F.J., Bueno-De-Mesquita, H.B., Calligaro, M., Jenab, M., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Jansen, E.H., Frohlich, J., Ayyobi, A., Overvad, K., Toft-Petersen, A.P., Tjonneland, A., Hansen, L., Boutron-Ruault, M.C., Clavel-Chapelon, F., Cottet, V., Palli, D., Tagliabue, G., Panico, S., Tumino, R., Vineis, P., Kaaks, R., Teucher, B., Boeing, H., Drogan, D., Trichopoulou, A., Lagiou, P., Dilis, V., Peeters, P.H., Siersema, P.D., Rodriguez, L., Gonzalez, C.A., Molina-Montes, E., Dorronsoro, M., Tormo, M.J., Barricarte, A., Palmqvist, R., Hallmans, G., Khaw, K.T., Tsilidis, K.K., Crowe, F.L., Chajes, V., Fedirko, V., Rinaldi, S., Norat, T. and Riboli, E.
Gut 60 (8): 1094-1102. August 2011

Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogeneic stem cell transplantation.
le Coutre, P., Meisel, H., Hofmann, J., Roecken, C., Vuong, G.L., Neuburger, S., Hemmati, P.G., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Arnold, R.
Gut 58 (5): 699-702. May 2009

Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder.
Andre, E., Gazzieri, D., Bardella, E., Ferreira, J., Mori, M.A., Saul, V.V., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Calixto, J.B., De Giorgio, R., Corinaldesi, R., Geppetti, P. and Trevisani, M.
Gut 57 (5): 628-633. May 2008

Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Petretti, T., Kemmner, W. ORCID: https://orcid.org/0000-0002-1494-7225, Schulze, B. and Schlag, P.M.
Gut 46 (3): 359-366. March 2000

Letter

Faecal microbiota composition associates with abdominal pain in the general population.
Hadizadeh, F., Bonfiglio, F., Belheouane, M., Vallier, M., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Bang, C., Bujanda, L., Andreasson, A., Agreus, L., Engstrand, L., Talley, N.J., Rafter, J., Baines, J.F., Walter, S., Franke, A. and D'Amato, M.
Gut 67 (4): 778-779. 8 March 2018