Browse by Journal Title

2023

Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.
Nurminen, A. and Jaatinen, S. and Taavitsainen, S. and Högnäs, G. and Lesluyes, T. and Ansari-Pour, N. and Tolonen, T. and Haase, K. and Koskenalho, A. and Kankainen, M. and Jasu, J. and Rauhala, H. and Kesäniemi, J. and Nikupaavola, T. and Kujala, P. and Rinta-Kiikka, I. and Riikonen, J. and Kaipia, A. and Murtola, T. and Tammela, T.L. and Visakorpi, T. and Nykter, M. and Wedge, D.C. and Van Loo, P. and Bova, G.S.
Genome Medicine 15 (1): 82. 12 October 2023

Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions.
Tschernoster, N. and Erger, F. and Kohl, S. and Reusch, B. and Wenzel, A. and Walsh, S. and Thiele, H. and Becker, C. and Franitza, M. and Bartram, M.P. and Kömhoff, M. and Schumacher, L. and Kukat, C. and Borodina, T. and Quedenau, C. and Nürnberg, P. and Rinschen, M.M. and Driller, J.H. and Pedersen, B.P. and Schlingmann, K.P. and Hüttel, B. and Bockenhauer, D. and Beck, B. and Altmüller, J.
Genome Medicine 15 (1): 62. 23 August 2023

A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A. and Haenig, C. and Neuendorf, N. and Blanc, E. and Ivanov, A. and Kirchner, M. and Schleumann, P. and Bayraktaroğlu, I. and Richter, M. and Molenda, C.M. and Sporbert, A. and Zenkner, M. and Schnoegl, S. and Suenkel, C. and Schneider, L.S. and Rybak-Wolf, A. and Kochnowsky, B. and Byrne, L.M. and Wild, E.J. and Nielsen, J.E. and Dittmar, G. and Peters, O. and Beule, D. and Wanker, E.E.
Genome Medicine 15 (1): 50. 20 July 2023

The gut microbiota in multiple sclerosis varies with disease activity.
Thirion, F. and Sellebjerg, F. and Fan, Y. and Lyu, L. and Hansen, T.H. and Pons, N. and Levenez, F. and Quinquis, B. and Stankevic, E. and Søndergaard, H.B. and Dantoft, T.M. and Poulsen, C.S. and Forslund, S.K. and Vestergaard, H. and Hansen, T. and Brix, S. and Oturai, A. and Sørensen, P.S. and Ehrlich, S.D. and Pedersen, O.
Genome Medicine 15 (1): 1. 5 January 2023

2022

Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury.
Hinze, C. and Kocks, C. and Leiz, J. and Karaiskos, N. and Boltengagen, A. and Cao, S. and Skopnik, C.M. and Klocke, J. and Hardenberg, J.H. and Stockmann, H. and Gotthardt, I. and Obermayer, B. and Haghverdi, L. and Wyler, E. and Landthaler, M. and Bachmann, S. and Hocke, A.C. and Corman, V. and Busch, J. and Schneider, W. and Himmerkus, N. and Bleich, M. and Eckardt, K.U. and Enghard, P. and Rajewsky, N. and Schmidt-Ott, K.M.
Genome Medicine 14 (1): 103. 9 September 2022

2021

Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis.
Bernardo-Faura, M. and Rinas, M. and Wirbel, J. and Pertsovskaya, I. and Pliaka, V. and Messinis, D.E. and Vila, G. and Sakellaropoulos, T. and Faigle, W. and Stridh, P. and Behrens, J.R. and Olsson, T. and Martin, R. and Paul, F. and Alexopoulos, L.G. and Villoslada, P. and Saez-Rodriguez, J.
Genome Medicine 13 (1): 117. 16 July 2021

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C. and Mouktaroudi, M. and Krämer, B. and Oestreich, M. and Antonakos, N. and Nuesch-Germano, M. and Gkizeli, K. and Bonaguro, L. and Reusch, N. and Baßler, K. and Saridaki, M. and Knoll, R. and Pecht, T. and Kapellos, T.S. and Doulou, S. and Kröger, C. and Herbert, M. and Holsten, L. and Horne, A. and Gemünd, I.D. and Rovina, N. and Agrawal, S. and Dahm, K. and van Uelft, M. and Drews, A. and Lenkeit, L. and Bruse, N. and Gerretsen, J. and Gierlich, J. and Becker, M. and Händler, K. and Kraut, M. and Theis, H. and Mengiste, S. and Domenico, E. and Schulte-Schrepping, J. and Seep, L. and Raabe, J. and Hoffmeister, C. and ToVinh, M. and Keitel, V. and Rieke, G. and Talevi, V. and Skowasch, D. and Aziz, N.A. and Pickkers, P. and van de Veerdonk, F.L. and Netea, M.G. and Schultze, J.L. and Kox, M. and Breteler, M.M.B. and Nattermann, J. and Koutsoukou, A. and Giamarellos-Bourboulis, E.J. and Ulas, T.
Genome Medicine 13 (1): 7. 13 January 2021

2020

Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease.
Izarzugaza, J.M.G. and Ellesøe, S.G. and Doganli, C. and Ehlers, N.S. and Dalgaard, M.D. and Audain, E. and Dombrowsky, G. and Banasik, K. and Sifrim, A. and Wilsdon, A. and Thienpont, B. and Breckpot, J. and Gewillig, M. and Brook, J.D. and Hitz, M.P. and Larsen, L.A. and Brunak, S.
Genome Medicine 12 (1): 76. 28 August 2020

cfNOMe - a single assay for comprehensive epigenetic analyses of cell-free DNA.
Erger, F. and Nörling, D. and Borchert, D. and Leenen, E. and Habbig, S. and Wiesener, M.S. and Bartram, M.P. and Wenzel, A. and Becker, C. and Toliat, M.R. and Nürnberg, P. and Beck, B.B. and Altmüller, J.
Genome Medicine 12 (1): 54. 24 June 2020

2017

Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naive Parkinson's disease patients.
Bedarf, J.R. and Hildebrand, F. and Coelho, L.P. and Sunagawa, S. and Bahram, M. and Goeser, F. and Bork, P. and Wuellner, U.
Genome Medicine 9 (1): 39. 28 April 2017

Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells.
Middelkamp, S. and van Heesch, S. and Braat, A.K. and de Ligt, J. and van Iterson, M. and Simonis, M. and van Roosmalen, M.J. and Kelder, M.J.E. and Kruisselbrink, E. and Hochstenbach, R. and Verbeek, N.E. and Ippel, E.F. and Adolfs, Y. and Pasterkamp, R.J. and Kloosterman, W.P. and Kuijk, E.W. and Cuppen, E.
Genome Medicine 9 (1): 9. 26 January 2017

2016

The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.
Czimmerer, Z. and Varga, T. and Kiss, M. and Vazquez, C.O. and Doan-Xuan, Q.M. and Rueckerl, D. and Tattikota, S.G. and Yan, X. and Nagy, Z.S. and Daniel, B. and Poliska, S. and Horvath, A. and Nagy, G. and Varallyay, E. and Poy, M.N. and Allen, J.E. and Bacso, Z. and Abreu-Goodger, C. and Nagy, L.
Genome Medicine 8 (1): 63. 31 May 2016

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P. and Kaergel, E. and Heinig, M. and Fontaine, J.F. and Patone, G. and Muro, E.M. and Mathas, S. and Hummel, M. and Andrade-Navarro, M.A. and Hübner, N. and Scheidereit, C.
Genome Medicine 8 (1): 28. 17 March 2016

2014

Modules, networks and systems medicine for understanding disease and aiding diagnosis.
Gustafsson, M. and Nestor, C.E. and Zhang, H. and Barabási, A.L. and Baranzini, S. and Brunak, S. and Chung, K.F. and Federoff, H.J. and Gavin, A.C. and Meehan, R.R. and Picotti, P. and Pujana, M.À. and Rajewsky, N. and Smith, K.G.C. and Sterk, P.J. and Villoslada, P. and Benson, M.
Genome Medicine 6 (10): 82. 17 October 2014

2013

De novo truncating mutations in ASXL3 are associated with a novel clinical phenotype with similarities to Bohring-Opitz syndrome.
Bainbridge, M.N. and Hu, H. and Muzny, D.M. and Musante, L. and Lupski, J.R. and Graham, B.H. and Chen, W. and Gripp, K.W. and Jenny, K. and Wienker, T.F. and Yang, Y. and Sutton, V.R. and Gibbs, R.A. and Ropers, H.H.
Genome Medicine 5 (2): 11. 5 February 2013

2012

Mining the literature: new methods to exploit keyword profiles.
Andrade-Navarro, M.A.
Genome Medicine 4 (10): 81. 30 October 2012

2009

Linking genes to diseases: it's all in the data.
Tiffin, N. and Andrade-Navarro, M.A. and Perez-Iratxeta, C.
Genome Medicine 1 (8): 77. 7 August 2009

Novel insights into proteomic technologies and their clinical perspective.
Dittmar, G. and Selbach, M.
Genome Medicine 1 (5): 53. 21 May 2009