Article

The baseline examinations of the German National Cohort (NAKO): recruitment protocol, response, and weighting.
Rach, S. ORCID: https://orcid.org/0000-0001-5241-0253, Sand, M., Reineke, A. ORCID: https://orcid.org/0000-0002-0092-4110, Becher, H. ORCID: https://orcid.org/0000-0002-8808-6667, Greiser, K.H., Wolf, K. ORCID: https://orcid.org/0000-0002-4343-201X, Wirkner, K. ORCID: https://orcid.org/0009-0000-1301-7125, Schmidt, C.O., Schipf, S. ORCID: https://orcid.org/0000-0002-2700-5317, Jöckel, K.H. ORCID: https://orcid.org/0000-0002-1987-0255, Krist, L., Ahrens, W. ORCID: https://orcid.org/0000-0003-3777-570X, Brenner, H., Castell, S. ORCID: https://orcid.org/0000-0003-1762-8462, Gastell, S., Harth, V. ORCID: https://orcid.org/0000-0003-4308-223X, Holleczek, B. ORCID: https://orcid.org/0000-0001-8759-4371, Ittermann, T. ORCID: https://orcid.org/0000-0002-0154-7353, Janisch-Fabian, S., Karch, A., Keil, T. ORCID: https://orcid.org/0000-0002-9108-3360, Klett-Tammen, C.J. ORCID: https://orcid.org/0000-0001-9685-5369, Kluttig, A. ORCID: https://orcid.org/0000-0003-4446-9938, Kuß, O. ORCID: https://orcid.org/0000-0003-3301-5869, Leitzmann, M., Lieb, W. ORCID: https://orcid.org/0000-0003-2544-4460, Meinke-Franze, C. ORCID: https://orcid.org/0000-0001-6137-9702, Michels, K.B., Mikolajczyk, R. ORCID: https://orcid.org/0000-0003-1271-7204, Moreno Velásquez, I. ORCID: https://orcid.org/0000-0001-6058-8983, Obi, N. ORCID: https://orcid.org/0000-0002-0903-9142, Övermöhle, C., Peters, A., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Rospleszcz, S. ORCID: https://orcid.org/0000-0002-4788-2341, Schmidt, B., Schulze, M.B. ORCID: https://orcid.org/0000-0002-0830-5277, Stang, A., Teismann, H. ORCID: https://orcid.org/0000-0001-5807-5572, Töpfer, C., Wolff, R. and Günther, K. ORCID: https://orcid.org/0000-0003-3801-4769
European Journal of Epidemiology 40 (4): 475-789. April 2025

Framework and baseline examination of the German National Cohort (NAKO).
Peters, A. ORCID: https://orcid.org/0000-0001-6645-0985, Peters, A., Greiser, K.H., Göttlicher, S., Ahrens, W., Albrecht, M., Bamberg, F., Bärnighausen, T., Becher, H., Berger, K., Beule, A., Boeing, H., Bohn, B., Bohnert, K., Braun, B., Brenner, H., Bülow, R., Castell, S., Damms-Machado, A., Dörr, M., Ebert, N., Ecker, M., Emmel, C., Fischer, B., Franzke, C.W., Gastell, S., Giani, G., Günther, M., Günther, K., Günther, K.P., Haerting, J., Haug, U., Heid, I.M., Heier, M., Heinemeyer, D., Hendel, T., Herbolsheimer, F., Hirsch, J., Hoffmann, W., Holleczek, B., Hölling, H., Hörlein, A., Jöckel, K.H., Kaaks, R., Karch, A., Karrasch, S., Kartschmit, N., Kauczor, H.U., Keil, T., Kemmling, Y., Klee, B., Klüppelholz, B., Kluttig, A., Kofink, L., Köttgen, A., Kraft, D., Krause, G., Kretz, L., Krist, L., Kühnisch, J., Kuß, O., Legath, N., Lehnich, A.T., Leitzmann, M., Lieb, W., Linseisen, J., Loeffler, M., Macdonald, A., Maier-Hein, K.H., Mangold, N., Meinke-Franze, C., Meisinger, C., Melzer, J., Mergarten, B., Michels, K.B., Mikolajczyk, R., Moebus, S., Mueller, U., Nauck, M., Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Nikolaou, K., Obi, N., Ostrzinski, S., Panreck, L., Pigeot, I., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Pschibul-Thamm, I., Rathmann, W., Reineke, A., Roloff, S., Rujescu, D., Rupf, S., Sander, O., Schikowski, T., Schipf, S., Schirmacher, P., Schlett, C.L., Schmidt, B., Schmidt, G., Schmidt, M., Schöne, G., Schulz, H., Schulze, M.B., Schweig, A., Sedlmeier, A.M., Selder, S., Six-Merker, J., Sowade, R., Stang, A., Stegle, O., Steindorf, K., Stübs, G., Swart, E., Teismann, H., Thiele, I., Thierry, S., Ueffing, M., Völzke, H., Waniek, S., Weber, A., Werner, N., Wichmann, H.E., Willich, S.N., Wirkner, K., Wolf, K., Wolff, R., Zeeb, H., Zinkhan, M. and Zschocke, J.
European Journal of Epidemiology 37 (10): 1107-1124. October 2022

Statistical analysis in the German National Cohort (NAKO) - specific aspects and general recommendations.
Kuss, O. ORCID: https://orcid.org/0000-0003-3301-5869, Becher, H., Wienke, A., Ittermann, T., Ostrzinski, S., Schipf, S., Schmidt, C.O., Leitzmann, M., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Krist, L., Roll, S., Sand, M., Pohlabeln, H., Rach, S., Jöckel, K.H., Stang, A., Mueller, U.A., Werdecker, A., Westerman, R., Greiser, K.H. and Michels, K.B.
European Journal of Epidemiology 37 (4): 429-436. April 2022

Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts.
Floegel, A., Kühn, T., Sookthai, D., Johnson, T., Prehn, C., Rolle-Kampczyk, U., Otto, W., Weikert, C., Illig, T., von Bergen, M., Adamski, J., Boeing, H., Kaaks, R. and Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X
European Journal of Epidemiology 33 (1): 55-66. January 2018

Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies.
Nimptsch, K. ORCID: https://orcid.org/0000-0001-7877-205X, Song, M., Aleksandrova, K., Katsoulis, M., Freisling, H., Jenab, M., Gunter, M.J., Tsilidis, K.K., Weiderpass, E., Bueno-De-Mesquita, H.B., Chong, D.Q., Jensen, M.K., Wu, C., Overvad, K., Kühn, T., Barrdahl, M., Melander, O., Jirstrom, K., Peeters, P.H., Sieri, S., Panico, S., Cross, A.J., Riboli, E., Van Guelpen, B., Myte, R., Huerta, J.M., Rodriguez-Barranco, M., Quirós, J.R., Dorronsoro, M., Tjønneland, A., Olsen, A., Travis, R., Boutron-Ruault, M.C., Carbonnel, F., Severi, G., Bonet, C., Palli, D., Janke, J. ORCID: https://orcid.org/0000-0003-0113-4118, Lee, Y.A. ORCID: https://orcid.org/0000-0002-1817-9163, Boeing, H., Giovannucci, E.L., Ogino, S., Fuchs, C.S., Rimm, E., Wu, K., Chan, A.T. and Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X
European Journal of Epidemiology 32 (5): 419-430. May 2017

Biomarker patterns of inflammatory and metabolic pathways are associated with risk of colorectal cancer: results from the European Prospective Investigation into Cancer and Nutrition (EPIC).
Aleksandrova, K., Jenab, M., Bueno-de-Mesquita, H.B., Fedirko, V., Kaaks, R., Lukanova, A., van Duijnhoven, F.J.B., Jansen, E., Rinaldi, S., Romieu, I., Ferrari, P., Murphy, N., Gunter, M.J., Riboli, E., Westhpal, S., Overvad, K., Tjønneland, A., Halkjær, J., Boutron-Ruault, M.C., Dossus, L., Racine, A., Trichopoulou, A., Bamia, C., Orfanos, P., Agnoli, C., Palli, D., Panico, S., Tumino, R., Vineis, P., Peeters, P.H., Duell, E.J., Molina-Montes, E., Quirós, J.R., Dorronsoro, M., Chirlaque, M.D., Barricarte, A., Ljuslinder, I., Palmqvist, R., Travis, R.C., Khaw, K.T., Wareham, N., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X and Boeing, H.
European Journal of Epidemiology 29 (4): 261-275. 1 April 2014

Estimation of the contribution of biomarkers of different metabolic pathways to risk of type 2 diabetes.
Montonen, J., Drogan, D., Joost, H.G., Boeing, H., Fritsche, A., Schleicher, E., Schulze, M.B. and Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X
European Journal of Epidemiology 26 (1): 29-38. January 2011

Association of a diabetes risk score with risk of myocardial infarction, stroke, specific types of cancer, and mortality: a prospective study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam cohort.
Heidemann, C., Boeing, H., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Noethlings, U., Joost, H.G. and Schulze, M.B.
European Journal of Epidemiology 24 (6): 281-288. June 2009

Comparison of relative and attributable risk of myocardial infarction and stroke according to C-reactive protein and low-density lipoprotein cholesterol levels.
Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Moehlig, M., Hoffmann, K., Spranger, J., Weikert, C., Willich, S.N., Pfeiffer, A.F. and Boeing, H.
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EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries.
Danesh, J., Saracci, R., Berglund, G., Feskens, E., Overvad, K., Panico, S., Thompson, S., Fournier, A., Clavel-Chapelon, F., Canonico, M., Kaaks, R., Linseisen, J., Boeing, H., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Weikert, C., Olsen, A., Tjonneland, A., Johnsen, S.P., Jensen, M.K., Quiros, J.R., Svatetz, C.A., Perez, M.J., Larranaga, N., Sanchez, C.N., Iribas, C.M., Bingham, S., Khaw, K.T., Wareham, N., Key, T., Roddam, A., Trichopoulou, A., Benetou, V., Trichopoulos, D., Masala, G., Sieri, S., Tumino, R., Sacerdote, C., Mattiello, A., Verschuren, W.M., Bueno-de-Mesquita, H.B., Grobbee, D.E., van der Schouw, Y.T., Melander, O., Hallmans, G., Wennberg, P., Lund, E., Kumle, M., Skeie, G., Ferrari, P., Slimani, N., Norat, T. and Riboli, E.
European Journal of Epidemiology 22 (2): 129-141. February 2007